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127 Companies |
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123 Products |
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123 Products |
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59 Mechanisms of Action |
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6 Trials |
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3245 News |
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- |||||||||| Solithera (solithromycin) / Melinta Therap, Fujifilm Holdings
New P3 trial: SOLITAIRE-U: Efficacy and Safety Study of Oral Solithromycin Compared to Intramuscular Ceftriaxone Plus Oral Azithromycin in the Treatment of Patients With Gonorrhea (clinicaltrials.gov) - Aug 6, 2014
P3, N=300, Not yet recruiting, Sponsor: Cempra Pharmaceuticals
- Enrollment open, Trial initiation date: NIDIAGDigest: Diagnosis of Neglected Tropical Diseases Among Patients With Persistent Digestive Disorders (clinicaltrials.gov) - Aug 6, 2014
P=N/A, N=4000, Recruiting, Sponsor: Swiss Tropical & Public Health Institute
Not yet recruiting --> Recruiting | Initiation date: Apr 2014 --> Jul 2014
- trimethoprim/sulfamethoxazole / Generic mfg., rifampicin / Generic mfg.
Trial completion: Randomized Clinical Trial to Compare a Regimen of Trimethoprim-sulfamethoxazole Plus Rifampicin With a Regimen of Linezolid in the Treatment of Methicillin-Resistant Staphylococcus Aureus (MRSA) Infection (clinicaltrials.gov) - Aug 5, 2014
P4, N=150, Completed, Sponsor: University Hospital, Geneva
Not yet recruiting --> Recruiting | Initiation date: Apr 2014 --> Jul 2014 Recruiting --> Completed
- || Trial primary completion date: Safety & Efficacy of an Antibacterial Protein Molecule Applied Topically to the Nostrils of Volunteers and Patients (clinicaltrials.gov) - Aug 5, 2014
P1/2, N=64, Recruiting, Sponsor: GangaGen, Inc.
Recruiting --> Completed Trial primary completion date: Dec 2013 --> Dec 2014
- || New P3 trial: RGNOSIS: Ecological Effects of Decolonisation Strategies in Intensive Care (clinicaltrials.gov) - Aug 4, 2014
P3, N=10700, Recruiting, Sponsor: MJM Bonten
- flucloxacillin sodium / Generic mfg.
Enrollment open, Trial initiation date: DANCE: Duration of ANtibiotic Therapy for CEllulitis (clinicaltrials.gov) - Aug 4, 2014
P4, N=396, Recruiting, Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Trial primary completion date: Dec 2013 --> Dec 2014 Not yet recruiting --> Recruiting | Initiation date: Feb 2014 --> Aug 2014
- || Trial primary completion date: BACTOvation™: Efficacy and Safety of Auriclosene (NVC-422) in the Treatment of Bacterial Conjunctivitis (clinicaltrials.gov) - Aug 1, 2014
P2, N=250, Recruiting, Sponsor: NovaBay Pharmaceuticals, Inc.
Not yet recruiting --> Recruiting | Initiation date: Feb 2014 --> Aug 2014 Trial primary completion date: Dec 2013 --> Sep 2014
- PREVNAR 13 (pneumococcal 13-valent conjugate vaccine) / Pfizer
Trial primary completion date: A Phase IIb, Open-Label, Dose Ranging Study of 13-Valent Pneumococcal Conjugate Vaccine in Adults 55 Through 74 Years of Age Previously Vaccinated With 23-Valent Pneumococcal Polysaccharide Vaccine (clinicaltrials.gov) - Aug 1, 2014
P2b, N=882, Recruiting, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Trial primary completion date: Dec 2013 --> Sep 2014 Trial primary completion date: Apr 2014 --> Dec 2014
- ||||||| Trial completion: Randomized Controlled Trial of Killed Oral Cholera Vaccine in Kolkata (clinicaltrials.gov) - Aug 1, 2014
P3, N=69329, Completed, Sponsor: International Vaccine Institute
Trial primary completion date: Apr 2014 --> Dec 2014 Active, not recruiting --> Completed
- Trial completion: Study to Determine the Equivalence of Three Products Containing Metronidazole Benzoate. (clinicaltrials.gov) - Aug 1, 2014
P1, N=6, Completed, Sponsor: Verisfield UK Ltd. Greek Branch
Active, not recruiting --> Completed Not yet recruiting --> Completed
- | Trial completion, Licensing / partnership: Perinatal Infections in Pakistan (clinicaltrials.gov) - Jul 31, 2014
P=N/A, N=1500, Completed, Sponsor: NICHD Global Network for Women's and Children's Health
Not yet recruiting --> Completed Recruiting --> Completed
- || PREVNAR 13 (pneumococcal 13-valent conjugate vaccine) / Pfizer
Trial primary completion date: Safety Surveillance of Pneumococcal 13-valent Conjugate Vaccine Among Filipinos (clinicaltrials.gov) - Jul 30, 2014
P4, N=3000, Recruiting, Sponsor: Pfizer
Recruiting --> Completed Trial primary completion date: Jun 2014 --> Sep 2014
- ||||||| aztreonam / Generic mfg., vancomycin / Generic mfg., ceftaroline fosamil / Generic mfg.
Trial completion: Evaluation of Ceftaroline Fosamil Versus Vancomycin Plus Aztreonam in the Treatment of Patients With Skin Infections (clinicaltrials.gov) - Jul 30, 2014
P3, N=801, Completed, Sponsor: AstraZeneca
Trial primary completion date: Jun 2014 --> Sep 2014 Recruiting --> Completed
- Trial completion, Trial primary completion date: Vitamin D Supplementations as Adjunct to Anti-Tuberculosis Drugs in Mongolia (clinicaltrials.gov) - Jul 30, 2014
P=N/A, N=350, Completed, Sponsor: Harvard School of Public Health
Recruiting --> Completed Recruiting --> Completed | Trial primary completion date: Feb 2015 --> May 2014
- |||||||||| aztreonam / Generic mfg., vancomycin / Generic mfg., ceftaroline fosamil / Generic mfg.
New P3 trial: Evaluation of Ceftaroline Fosamil vs Vancomycin Plus Aztreonam in the Treatment of Patients With Skin Infections. (clinicaltrials.gov) - Jul 29, 2014
P3, N=60, Recruiting, Sponsor: AstraZeneca
- ||||| Solithera (solithromycin) / Melinta Therap, Fujifilm Holdings
Trial initiation date: SOLITAIRE-ORAL: Efficacy and Safety Study of Oral Solithromycin (CEM-101) Compared to Oral Moxifloxacin in Treatment of Patients With Community-Acquired Bacterial Pneumonia (clinicaltrials.gov) - Jul 26, 2014
P3, N=860, Ongoing, Sponsor: Cempra Pharmaceuticals, Inc.
Recruiting --> Completed | Trial primary completion date: Feb 2015 --> May 2014 Initiation date: Dec 2012 --> May 2013
- Nontuberculous mycobacteria: A Prospective, Multicenter, Collaborative Study to Determine the Prevalence of Nontuberculous Mycobacteria (NTM) in Pediatric Patients With Cystic Fibrosis in Florida (clinicaltrials.gov) - Jul 23, 2014
P=N/A, N=500, Recruiting, Sponsor: University of Miami
- || Enrollment closed: Safety and Immunogenicity of Nyaditum Resae® Probiotic to Protect From Tuberculosis (clinicaltrials.gov) - Jul 23, 2014
P=N/A, N=51, Active, not recruiting, Sponsor: Manresana de Micobacteriologia, SL
Initiation date: Dec 2012 --> May 2013 Recruiting --> Active, not recruiting
- ||| AMG 108 / AstraZeneca
Enrollment change: Assessment of the Safety, Tolerability and Efficacy of MEDI8968 in Subjects With Moderate to Severe Hidradenitis Suppurativa (clinicaltrials.gov) - Jul 23, 2014
P2a, N=224, Active, not recruiting, Sponsor: AstraZeneca
Recruiting --> Active, not recruiting N=100 --> 224
- ||| Clinical: LUXSOL(TM) Topical Cream for the Treatment of Symptomatic Bacterial Vaginosis; A Proof of Concept Study (clinicaltrials.gov) - Jul 23, 2014
P0, N=60, Recruiting, Sponsor: CDA Research Group, Inc.
- |||| ceftaroline fosamil / Generic mfg.
Trial completion: Safety and Efficacy Study of Ceftaroline in Subjects With Staphylococcus Aureus Bacteremia or With Persistent Methicillin-Resistant Staphylococcus Aureus Bacteremia (clinicaltrials.gov) - Jul 17, 2014
P4, N=56, Completed, Sponsor: Cerexa, Inc.
N=100 --> 224 Active, not recruiting --> Completed
- Gatiflox (gatifloxacin) / Orient Europharma
Enrollment closed, Head-to-Head: Gatifloxacin Versus Ceftriaxone in the Treatment of Enteric Fever (clinicaltrials.gov) - Jul 16, 2014
P4, N=300, Active, not recruiting, Sponsor: Oxford University Clinical Research Unit, Vietnam
Active, not recruiting --> Completed Recruiting --> Active, not recruiting
- ||||||| PREVNAR 13 (pneumococcal 13-valent conjugate vaccine) / Pfizer
Trial completion: A Study Evaluating 13-Valent Pneumococcal Conjugate Vaccine (13vPnC) In Healthy Infants In China (clinicaltrials.gov) - Jul 16, 2014
P3, N=1674, Completed, Sponsor: Pfizer
Recruiting --> Active, not recruiting Active, not recruiting --> Completed
- |||| Trumenba (meningococcal B vaccine) / Pfizer
Trial completion: A Study Evaluating Safety And Immunogenicity Of Meningococcal B Rlp2086 Vaccine In Adolescents (clinicaltrials.gov) - Jul 16, 2014
P2, N=538, Completed, Sponsor: Pfizer
Active, not recruiting --> Completed Active, not recruiting --> Completed
- ||| tigecycline / Generic mfg.
Enrollment closed, Trial primary completion date: Study Evaluating The Safety And Effectiveness In Subjects With Tigecycline Treatment (clinicaltrials.gov) - Jul 15, 2014
P4, N=742, Active, not recruiting, Sponsor: Pfizer
Active, not recruiting --> Completed Completed --> Active, not recruiting | Trial primary completion date: Jul 2013 --> Apr 2015
- | vancomycin / Generic mfg., trimethoprim/sulfamethoxazole / Generic mfg.
Enrollment closed: Cotrimoxazole Versus Vancomycin for Invasive Methicillin-resistant Staphylococcus Aureus Infections (clinicaltrials.gov) - Jul 15, 2014
P3, N=250, Active, not recruiting, Sponsor: Rabin Medical Center
Completed --> Active, not recruiting | Trial primary completion date: Jul 2013 --> Apr 2015 Recruiting --> Active, not recruiting
- ||||||| Quinvaxem (diphtheria, Tetanus, whole-cell pertussis- HiB - HepB) / GSK
Trial completion: A Comparison of the Immunogenicity and Safety of Quinvaxem in Mono-dose Vials and Uniject (clinicaltrials.gov) - Jul 15, 2014
P3, N=400, Completed, Sponsor: Crucell Holland BV
Recruiting --> Active, not recruiting Active, not recruiting --> Completed
- ||||||| Baxdela (delafloxacin) / Menarini, Melinta Therap
Trial completion: Delafloxacin Versus Vancomycin and Aztreonam for the Treatment of Acute Bacterial Skin and Skin Structure Infections (clinicaltrials.gov) - Jul 15, 2014
P3, N=660, Completed, Sponsor: Melinta Therapeutics, Inc.
Active, not recruiting --> Completed Recruiting --> Completed
- | Menveo (meningococcal-groups A, C, W-135 and Y oligosaccharide CRM197 conjugate vaccine) / GSK
Clinical: Safety of One Dose of Meningococcal ACWY Conjugate Vaccine in Subjects From 2 Months to 55 Years of Age in the Republic of South Korea (clinicaltrials.gov) - Jul 15, 2014
P4, N=3300, Recruiting, Sponsor: Novartis Vaccines
Recruiting --> Completed Phase classification: P=N/A --> P4
- Trial primary completion date, HEOR, Cost effectiveness: Cost-effectiveness of Two Forms of DOTS in a Demonstration Area of the DOTS Strategy in Colombia (clinicaltrials.gov) - Jul 14, 2014
P=N/A, N=264, Active, not recruiting, Sponsor: Fundación FES
Phase classification: P=N/A --> P4 Trial primary completion date: Oct 2013 --> Aug 2014
- Enrollment closed, Trial primary completion date: Improving Diagnosis of Tuberculosis in HIV Infected Children in Asia (Cambodia, Vietnam)and Africa (Burkina Faso, Cameroon) (clinicaltrials.gov) - Jul 14, 2014
P=N/A, N=441, Active, not recruiting, Sponsor: French National Institute for Health and Medical Research-French National Agency for Research on AIDS and Viral Hepatitis (Inserm-ANRS)
Trial primary completion date: Oct 2013 --> Aug 2014 Recruiting --> Active, not recruiting | Trial primary completion date: May 2014 --> Dec 2014
- Trial completion, Pneumococcal vaccines: Bacterial Pneumonia Score (BPS) Guided Antibiotic Use in Children With Pneumonia and Pneumococcal Vaccine (clinicaltrials.gov) - Jul 14, 2014
P=N/A, N=60, Completed, Sponsor: Hospital General de Niños Pedro de Elizalde
Recruiting --> Active, not recruiting | Trial primary completion date: May 2014 --> Dec 2014 Recruiting --> Completed
- ||||| Nimenrix (MenACWY-TT) / Pfizer
Enrollment closed: Comparison of GlaxoSmithKline (GSK)134612 in Subjects With Increased Risk for Meningococcal Disease Versus Healthy Subjects (clinicaltrials.gov) - Jul 14, 2014
P3, N=100, Active, not recruiting, Sponsor: GlaxoSmithKline
Recruiting --> Completed Recruiting --> Active, not recruiting
- |||| RotaTeq (Live attenuated pentavalent Rotavirus oral vaccine) / Merck (MSD)
Trial completion: Immunogenicity and Safety of Concomitant Administration of RotaTeq™ (V260) and the Diphtheria, Tetanus, Pertussis and Inactivated Poliovirus Vaccine (DTP-IPV) in Healthy Japanese Infants (V260-060) (clinicaltrials.gov) - Jul 12, 2014
P4, N=190, Completed, Sponsor: Merck Sharp & Dohme Corp.
Recruiting --> Active, not recruiting Active, not recruiting --> Completed
- Trial completion: Impact of Vitamin D Supplementation on Host Immunity to Mycobacterium Tuberculosis and Response to Treatment (clinicaltrials.gov) - Jul 12, 2014
P2, N=199, Completed, Sponsor: Emory University
Active, not recruiting --> Completed Active, not recruiting --> Completed
- | Pneumovax 23 (23-valent pneumococcal polysaccharide) / Merck (MSD), Boostrix (tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccine) / GSK
Trial completion, Pneumococcal vaccines: PneuMum: Pneumococcal Vaccination of Australian Indigenous Mothers (clinicaltrials.gov) - Jul 12, 2014
P3, N=227, Completed, Sponsor: Menzies School of Health Research
Active, not recruiting --> Completed Recruiting --> Completed
- || Enrollment change: Detection of Chlamydia (CT) and Gonorrhea (NG) (clinicaltrials.gov) - Jul 10, 2014
P=N/A, N=700, Recruiting, Sponsor: Meridian Bioscience, Inc.
Recruiting --> Completed N=6600 --> 700
- Enrollment change: A Clinical Challenge Study of BCG in Healthy Volunteers (clinicaltrials.gov) - Jul 10, 2014
P=N/A, N=52, Recruiting, Sponsor: University of Oxford
N=6600 --> 700 N=40 --> 52
- Enrollment closed: Phase I Trial Evaluating Safety and Immunogenicity of MVA85A-IMX313 Compared to MVA85A in BCG Vaccinated Adults (clinicaltrials.gov) - Jul 10, 2014
P1, N=30, Active, not recruiting, Sponsor: University of Oxford
N=40 --> 52 Recruiting --> Active, not recruiting
- Enrollment closed: Safety Study of ChAdOx1 85A Vaccination With and Without MVA85A Boost in Healthy Adults (clinicaltrials.gov) - Jul 10, 2014
P1, N=30, Active, not recruiting, Sponsor: University of Oxford
Recruiting --> Active, not recruiting Recruiting --> Active, not recruiting
- || Trial primary completion date: Assessing Contacts' Decision Making on Reducing the Risk of Pertussis Transmission to Newborns Through Immunisation (clinicaltrials.gov) - Jul 8, 2014
P=N/A, N=700, Not yet recruiting, Sponsor: GlaxoSmithKline
Recruiting --> Active, not recruiting Trial primary completion date: Oct 2014 --> May 2015
- Enrollment open: IFN-gamma-releasing Assay Based Approach in Patients With Suspected Tuberculous Peritonitis (clinicaltrials.gov) - Jul 8, 2014
P=N/A, N=90, Recruiting, Sponsor: Asan Medical Center
Trial primary completion date: Oct 2014 --> May 2015 Not yet recruiting --> Recruiting
- ||||| Adacel (tetanus toxoid/reduced diphtheria toxoid/acellular pertussis vaccine adsorbed) / Sanofi
Enrollment closed: Study of SP306 Given Intramuscularly Compared to DT BIK® Given Subcutaneously in Japanese Adolescents 11 - 12 Years Old (clinicaltrials.gov) - Jul 8, 2014
P3, N=534, Active, not recruiting, Sponsor: Sanofi Pasteur, a Sanofi Company
Not yet recruiting --> Recruiting Recruiting --> Active, not recruiting
- Trial primary completion date: RCT: Triple vs Sequential vs Concomitant Therapy H Pylori (clinicaltrials.gov) - Jul 8, 2014
P4, N=462, Completed, Sponsor: Changi General Hospital
Recruiting --> Active, not recruiting Trial primary completion date: Dec 2014 --> Jun 2014
- ||| AMG 108 / AstraZeneca
Enrollment closed: Assessment of the Safety, Tolerability and Efficacy of MEDI8968 in Subjects With Moderate to Severe Hidradenitis Suppurativa (clinicaltrials.gov) - Jul 8, 2014
P2a, N=100, Active, not recruiting, Sponsor: AstraZeneca
Trial primary completion date: Dec 2014 --> Jun 2014 Recruiting --> Active, not recruiting
- Trial completion, Trial primary completion date: RCT: Triple vs Sequential vs Concomitant Therapy H Pylori (clinicaltrials.gov) - Jul 8, 2014
P4, N=462, Completed, Sponsor: Changi General Hospital
Recruiting --> Active, not recruiting Recruiting --> Completed | Trial primary completion date: Dec 2014 --> Jun 2014
- |||| Trial primary completion date: Immunogenicity and Safety of Meningococcal ACWY Conjugate Vaccine in Healthy Subjects From 2 to 75 Years of Age in India (clinicaltrials.gov) - Jul 7, 2014
P3, N=180, Completed, Sponsor: Novartis
Recruiting --> Completed | Trial primary completion date: Dec 2014 --> Jun 2014 Trial primary completion date: Jul 2014 --> Apr 2014
- ||||||| Trial completion, Trial primary completion date: Immunogenicity and Safety of Meningococcal ACWY Conjugate Vaccine in Healthy Subjects From 2 to 75 Years of Age in India (clinicaltrials.gov) - Jul 7, 2014
P3, N=180, Completed, Sponsor: Novartis
Trial primary completion date: Jul 2014 --> Apr 2014 Active, not recruiting --> Completed | Trial primary completion date: Jul 2014 --> Apr 2014
- Enrollment open: High Dose Amoxicillin Versus Tetracycline as Second-line Treatment of Resistant Helicobacter Pylori Infection (clinicaltrials.gov) - Jul 4, 2014
P4, N=200, Recruiting, Sponsor: Shanghai Jiao Tong University School of Medicine
Active, not recruiting --> Completed | Trial primary completion date: Jul 2014 --> Apr 2014 Not yet recruiting --> Recruiting
- ||||| Humira (adalimumab) / Eisai, AbbVie
Enrollment closed: PIONEER (OLE): Open-label Study of the Safety and Efficacy of Adalimumab in the Treatment of Hidradenitis Suppurativa (clinicaltrials.gov) - Jul 4, 2014
P3, N=540, Active, not recruiting, Sponsor: AbbVie (prior sponsor, Abbott)
Not yet recruiting --> Recruiting Enrolling by invitation --> Active, not recruiting