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127 Companies |
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123 Products |
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123 Products |
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59 Mechanisms of Action |
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6 Trials |
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3245 News |
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- | Trial completion, Surgery: The Effect of Sodium Bicarbonate on Postoperative Renal Function in Infective Endocarditis Patients Undergoing Open Heart Surgery (clinicaltrials.gov) - Jul 17, 2018
P4, N=70, Completed, Sponsor: Yonsei University
Recruiting --> Completed
- | Minocin for injection (minocycline intravenous) / Melinta Therap
Trial completion, Adverse events, Real-world evidence, Real-world, Gram negative: A Retrospective Observational Study to Evaluate the Utilization, Outcomes, and Adverse Events in Participants Treated With Minocin (clinicaltrials.gov) - Jul 6, 2018
P=N/A, N=71, Completed, Sponsor: Rempex (a wholly owned subsidiary of Melinta Therapeutics, Inc.)
Recruiting --> Completed Recruiting --> Completed
- | Trial completion, Enrollment change: Simplified GBS Screening and Prevalence of ESBL in Pregnant Women (clinicaltrials.gov) - Jul 3, 2018
P=N/A, N=250, Completed, Sponsor: University Hospital, Basel, Switzerland
Recruiting --> Completed Recruiting --> Completed | N=480 --> 250
- | Trial completion, Enrollment change: Effect of Passive Ultrasonic Irrigation on the Reduction of Bacteria and Endotoxins in Root Canals (clinicaltrials.gov) - Jul 3, 2018
P=N/A, N=66, Completed, Sponsor: University of Sao Paulo
Recruiting --> Completed | N=480 --> 250 Active, not recruiting --> Completed | N=40 --> 66
- | colistin sulphate / Generic mfg.
Trial completion, Enrollment change, Trial completion date, Trial primary completion date: Impact of Plasma Levels of Colistin in Patients With Carbapenem Resistant Acinetobacter Baumannii Infection (clinicaltrials.gov) - Jun 27, 2018
P=N/A, N=30, Completed, Sponsor: DongGuk University
Active, not recruiting --> Completed | N=40 --> 66 Recruiting --> Completed | N=50 --> 30 | Trial completion date: Dec 2016 --> Apr 2018 | Trial primary completion date: Dec 2015 --> Jan 2018
- | Trial completion, Enrollment change, Trial primary completion date: Clarithromycin Triple Therapy Plus Bismuth for Helicobacter Pylori First-line Treatment (clinicaltrials.gov) - Jun 26, 2018
P4, N=66, Completed, Sponsor: Shanghai Jiao Tong University School of Medicine
Recruiting --> Completed | N=50 --> 30 | Trial completion date: Dec 2016 --> Apr 2018 | Trial primary completion date: Dec 2015 --> Jan 2018 Recruiting --> Completed | N=393 --> 66 | Trial primary completion date: Jul 2017 --> Sep 2017
- | Trial primary completion date: CATS-CARE: Combining Opioid Addiction Treatment Services With CARe for Infectious Endocarditis (clinicaltrials.gov) - Jun 18, 2018
P=N/A, N=20, Recruiting, Sponsor: Laura Fanucchi
Recruiting --> Completed | N=393 --> 66 | Trial primary completion date: Jul 2017 --> Sep 2017 Trial primary completion date: Aug 2018 --> Dec 2018
- | Phase classification: Assessment of Antibody Persistence at Eighteen Months After the Completion of the Vaccination Course in Study V72P10 (clinicaltrials.gov) - Jun 15, 2018
P2b, N=817, Completed, Sponsor: Novartis Vaccines
Trial primary completion date: Aug 2018 --> Dec 2018 Phase classification: P2/3 --> P2b
- | Trial completion: Epidemiology of Community - Associated Extended-spectrum Beta-lactamases (ESBL) Producing Escherichia Coli (clinicaltrials.gov) - Jun 14, 2018
P=N/A, N=300, Completed, Sponsor: University of Pittsburgh
Phase classification: P2/3 --> P2b Active, not recruiting --> Completed
- | Clinical data, Trial completion, Trial completion date, Trial primary completion date: Multinational Study of Acinetobacter Bloodstream Infection: Clinical Outcomes and Global Epidemiology-PITT Protocol (clinicaltrials.gov) - Jun 14, 2018
P=N/A, N=100, Completed, Sponsor: University of Pittsburgh
Active, not recruiting --> Completed Recruiting --> Completed | Trial completion date: Dec 2025 --> Dec 2017 | Trial primary completion date: Dec 2025 --> Dec 2017
- | Trial completion, Trial completion date, Trial primary completion date: Risk Factors for Quinolone Resistance Among ESBL Producing Klebsiella Species (clinicaltrials.gov) - Jun 14, 2018
P=N/A, N=500, Completed, Sponsor: University of Pittsburgh
Recruiting --> Completed | Trial completion date: Dec 2025 --> Dec 2017 | Trial primary completion date: Dec 2025 --> Dec 2017 Active, not recruiting --> Completed | Trial completion date: Dec 2025 --> Dec 2017 | Trial primary completion date: Dec 2025 --> Dec 2017
- | piperacillin sodium/tazobactam sodium / Generic mfg.
Trial completion, Trial completion date, Trial primary completion date: Piperacillin/Tazobactam for Bacteremia With Organisms Producing Chromosomally-Encoded AmpC Beta-Lactamase (clinicaltrials.gov) - Jun 14, 2018
P=N/A, N=1000, Completed, Sponsor: University of Pittsburgh
Active, not recruiting --> Completed | Trial completion date: Dec 2025 --> Dec 2017 | Trial primary completion date: Dec 2025 --> Dec 2017 Active, not recruiting --> Completed | Trial completion date: Dec 2025 --> Dec 2017 | Trial primary completion date: Dec 2025 --> Dec 2017
- ||| Trial completion, Trial completion date, Trial primary completion date: Clinical and Microbiologic Characteristics of Cephalosporin-Resistant E. Coli-PITT Protocol (clinicaltrials.gov) - Jun 14, 2018
P=N/A, N=150, Completed, Sponsor: University of Pittsburgh
Active, not recruiting --> Completed | Trial completion date: Dec 2025 --> Dec 2017 | Trial primary completion date: Dec 2025 --> Dec 2017 Active, not recruiting --> Completed | Trial completion date: Dec 2025 --> Dec 2017 | Trial primary completion date: Dec 2025 --> Dec 2017
- | piperacillin sodium/tazobactam sodium / Generic mfg.
Trial completion: Risk Factors for Piperacillin/Tazobactam Resistance in Extended-Spectrum Beta-Lactamase (ESBL) Producing Organisms (clinicaltrials.gov) - Jun 12, 2018
P=N/A, N=450, Completed, Sponsor: University of Pittsburgh
Active, not recruiting --> Completed | Trial completion date: Dec 2025 --> Dec 2017 | Trial primary completion date: Dec 2025 --> Dec 2017 Recruiting --> Completed
- | Trial completion: Rapid Strep Testing in Children With Recent Streptococcal Pharyngitis (clinicaltrials.gov) - Jun 7, 2018
P=N/A, N=600, Completed, Sponsor: Georgetown University
Recruiting --> Completed Recruiting --> Completed
- ||||||| Trial completion, Trial completion date, Trial primary completion date: Phase III Clinical Study of Efficacy and Safety of Vaccae (clinicaltrials.gov) - Jun 3, 2018
P3, N=10000, Completed, Sponsor: Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.
Recruiting --> Completed Recruiting --> Completed | Trial completion date: May 2018 --> Nov 2017 | Trial primary completion date: Apr 2018 --> Nov 2017
- ||||||| Solithera (solithromycin) / Melinta Therap, Fujifilm Holdings
Enrollment change, Trial completion date, Trial termination, Trial primary completion date: Safety and Efficacy of Solithromycin in Adolescents and Children With Community-Acquired Bacterial Pneumonia (clinicaltrials.gov) - May 31, 2018
P2/3, N=94, Terminated, Sponsor: Cempra Inc
Recruiting --> Completed | Trial completion date: May 2018 --> Nov 2017 | Trial primary completion date: Apr 2018 --> Nov 2017 N=400 --> 94 | Trial completion date: Dec 2018 --> Mar 2018 | Recruiting --> Terminated | Trial primary completion date: Dec 2018 --> Mar 2018; Development not proceeding
- | Trial completion date: TANDEM: Pulmonary Tuberculosis Patients With Diabetes Mellitus (clinicaltrials.gov) - May 4, 2018
P=N/A, N=350, Active, not recruiting, Sponsor: Universitas Padjadjaran
N=400 --> 94 | Trial completion date: Dec 2018 --> Mar 2018 | Recruiting --> Terminated | Trial primary completion date: Dec 2018 --> Mar 2018; Development not proceeding Trial completion date: Dec 2017 --> Dec 2018
- | lansoprazole / Generic mfg., clarithromycin / Generic mfg., amoxicillin / Generic mfg.
Trial completion, Trial completion date, Trial primary completion date: Intraluminal Therapy for Helicobacter Pylori Infection (clinicaltrials.gov) - May 2, 2018
P4, N=100, Completed, Sponsor: Mackay Memorial Hospital
Trial completion date: Dec 2017 --> Dec 2018 Recruiting --> Completed | Trial completion date: Apr 2019 --> Apr 2018 | Trial primary completion date: Dec 2018 --> Dec 2017
- ||| MTBVAC / Zendal Group
Trial completion, Trial completion date, IO biomarker: MTBVAC-Ph1b: Dose-escalation Safety and Immunogenicity Study to Compare MTBVAC to BCG in Newborns With a Safety Arm in Adults (clinicaltrials.gov) - May 1, 2018
P1/2, N=54, Completed, Sponsor: Biofabri, S.L
Recruiting --> Completed | Trial completion date: Apr 2019 --> Apr 2018 | Trial primary completion date: Dec 2018 --> Dec 2017 Active, not recruiting --> Completed | Trial completion date: Sep 2017 --> Mar 2018
- | Trial completion: PCS: Preventing Congenital Syphilis (clinicaltrials.gov) - Apr 26, 2018
P=N/A, N=60386, Completed, Sponsor: Tulane University School of Public Health and Tropical Medicine
Active, not recruiting --> Completed | Trial completion date: Sep 2017 --> Mar 2018 Active, not recruiting --> Completed
- | Trial completion, Enrollment change, Trial completion date: FemCure: Transmission of Genital and Extra-genital Chlamydia Trachomatis Infections in Women (clinicaltrials.gov) - Apr 26, 2018
P=N/A, N=560, Completed, Sponsor: Maastricht University Medical Center
Active, not recruiting --> Completed Recruiting --> Completed | N=400 --> 560 | Trial completion date: Dec 2019 --> Dec 2017
- | amikacin sulfate / Generic mfg.
Trial completion, Phase classification, Trial completion date, Trial primary completion date, Gram negative: Effect of Additional Nebulized Amikacin in Ventilator-Associated Pneumonia Caused by Gram Negative Bacteria (clinicaltrials.gov) - Apr 26, 2018
P=N/A, N=60, Completed, Sponsor: Thammasat University
Recruiting --> Completed | N=400 --> 560 | Trial completion date: Dec 2019 --> Dec 2017 Recruiting --> Completed | Phase classification: P4 --> PN/A | Trial completion date: Dec 2017 --> Apr 2018 | Trial primary completion date: May 2017 --> Apr 2018
- | Trial completion, Trial primary completion date: Systems Medicine to Study Necrotizing Soft Tissue Infections (NSTIs). (clinicaltrials.gov) - Apr 23, 2018
P=N/A, N=409, Completed, Sponsor: Karolinska Institutet
Recruiting --> Completed | Phase classification: P4 --> PN/A | Trial completion date: Dec 2017 --> Apr 2018 | Trial primary completion date: May 2017 --> Apr 2018 Recruiting --> Completed | Trial primary completion date: Oct 2017 --> Jun 2017
- | OligoG CF-5/20 / AlgiPharma
Trial completion, Trial completion date: A Study of OligoG in Cystic Fibrosis Subjects With Burkholderia Spp. Infection (clinicaltrials.gov) - Apr 19, 2018
P2, N=15, Completed, Sponsor: AlgiPharma AS
Recruiting --> Completed | Trial primary completion date: Oct 2017 --> Jun 2017 Active, not recruiting --> Completed | Trial completion date: May 2017 --> Dec 2017
- |||| VPM1002 / SAKK, Serum Institute of India
Trial completion: Study to Evaluate the Safety and Immunogenicity of VPM1002 in Comparison With BCG in HIV-exposed/-Unexposed Newborn Infants in South Africa (clinicaltrials.gov) - Apr 18, 2018
P2, N=416, Completed, Sponsor: Serum Institute of India Pvt. Ltd.
Active, not recruiting --> Completed | Trial completion date: May 2017 --> Dec 2017 Active, not recruiting --> Completed
- | colistin sulphate / Generic mfg.
Trial completion, Enrollment change: Clinical Usefulness of Therapeutic Drug Monitoring of Colistin in Patients Treated With Colistin. (clinicaltrials.gov) - Apr 18, 2018
P=N/A, N=15, Completed, Sponsor: Seoul National University Hospital
Active, not recruiting --> Completed Recruiting --> Completed | N=60 --> 15
- | Trial completion: Optimal Site for Rapid Urease Test in the Stomach (clinicaltrials.gov) - Apr 18, 2018
P=N/A, N=300, Completed, Sponsor: Soonchunhyang University Hospital
Recruiting --> Completed | N=60 --> 15 Recruiting --> Completed
- | Trial completion: Tailored Versus Empiric Therapy for Helicobacter Pylori Treatment (clinicaltrials.gov) - Apr 18, 2018
P4, N=382, Completed, Sponsor: Shanghai Jiao Tong University School of Medicine
Recruiting --> Completed Active, not recruiting --> Completed
- ||||||| Trial completion: Clinical Study of Recombinant Mycobacterium Tuberculosis ESAT6-CFP10 Allergen (clinicaltrials.gov) - Apr 12, 2018
P3, N=1090, Completed, Sponsor: Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.
Active, not recruiting --> Completed Recruiting --> Completed
- ||||||| Trial completion: Clinical Study of Recombinant Mycobacterium Tuberculosis ESAT6-CFP10 Allergen for Children (clinicaltrials.gov) - Apr 12, 2018
P3, N=96, Completed, Sponsor: Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.
Recruiting --> Completed Recruiting --> Completed
- | Enrollment closed: Tailored Versus Empiric Therapy for Helicobacter Pylori Treatment (clinicaltrials.gov) - Apr 12, 2018
P4, N=382, Active, not recruiting, Sponsor: Shanghai Jiao Tong University School of Medicine
Recruiting --> Completed Recruiting --> Active, not recruiting
- | Trial completion date, Trial primary completion date, Surgery: ORAL-ISO: Effect of Oral Preparation on Bacterial Colonization of the Pharyngeal Mucosa in Surgery of Head and Neck Cancer (clinicaltrials.gov) - Apr 11, 2018
P3, N=80, Recruiting, Sponsor: Rennes University Hospital
Recruiting --> Active, not recruiting Trial completion date: Dec 2017 --> Feb 2019 | Trial primary completion date: Nov 2017 --> Nov 2018
- ||| Trial completion, Trial completion date, Trial primary completion date: SF2a-TT15 Conjugate Vaccine in Healthy Adult Volunteers (clinicaltrials.gov) - Apr 11, 2018
P1, N=64, Completed, Sponsor: Institut Pasteur
Trial completion date: Dec 2017 --> Feb 2019 | Trial primary completion date: Nov 2017 --> Nov 2018 Not yet recruiting --> Completed | Trial completion date: May 2017 --> Dec 2017 | Trial primary completion date: Dec 2016 --> Jun 2017
- |||| AERAS-404 / Sanofi
Trial completion: Phase 1/II, Safety and Immunogenicity Study of AERAS-404 in BCG-Primed Infants (clinicaltrials.gov) - Apr 9, 2018
P1/2, N=243, Completed, Sponsor: Aeras
Not yet recruiting --> Completed | Trial completion date: May 2017 --> Dec 2017 | Trial primary completion date: Dec 2016 --> Jun 2017 Active, not recruiting --> Completed
- | Phase classification, Enrollment change, Trial termination: Penicillin Therapeutic Drug Monitoring in the Treatment of Infectious Syphilis. (clinicaltrials.gov) - Apr 6, 2018
P, N=25, Terminated, Sponsor: Ottawa Hospital Research Institute
Active, not recruiting --> Completed Phase classification: P=N/A --> P | N=120 --> 25 | Enrolling by invitation --> Terminated; Low enrollment.
- | Phase classification, Enrollment change: Collection of Tissue Specimens in Mali, West Africa, for HIV and Tuberculosis Research (clinicaltrials.gov) - Apr 6, 2018
P, N=253, Terminated, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Phase classification: P=N/A --> P | N=120 --> 25 | Enrolling by invitation --> Terminated; Low enrollment. Phase classification: P=N/A --> P | N=480 --> 253
- | Phase classification, Enrollment change: Immune Response to Mycobacterium Tuberculosis Infection (clinicaltrials.gov) - Apr 6, 2018
P, N=157, Completed, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Phase classification: P=N/A --> P | N=480 --> 253 Phase classification: P=N/A --> P | N=32 --> 157
- | Phase classification: Streptococcal Infection and Respiratory Distress in Newborns (clinicaltrials.gov) - Apr 6, 2018
P, N=13180, Completed, Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Phase classification: P=N/A --> P | N=32 --> 157 Phase classification: P=N/A --> P
- | Phase classification: Oral Urea Breath Testing for Diagnosis and Treatment Response in Pulmonary Tuberculosis (clinicaltrials.gov) - Apr 6, 2018
P, N=113, Completed, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Phase classification: P=N/A --> P Phase classification: P=N/A --> P
- | Phase classification, Enrollment change: Gene Expression in HIV and Tuberculosis Co-infection (clinicaltrials.gov) - Apr 6, 2018
P, N=96, Completed, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Phase classification: P=N/A --> P Phase classification: P=N/A --> P | N=20 --> 96
- | Phase classification, Enrollment change, IO biomarker: Multi-Drug Resistant Tuberculosis in Korea (clinicaltrials.gov) - Apr 6, 2018
P, N=777, Completed, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Phase classification: P=N/A --> P | N=20 --> 96 Phase classification: P=N/A --> P | N=2040 --> 777
- | Phase classification: Tuberculosis in China (clinicaltrials.gov) - Apr 6, 2018
P, N=199, Completed, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Phase classification: P=N/A --> P | N=2040 --> 777 Phase classification: P=N/A --> P
- | Phase classification, Enrollment change: Utility of MODS for Diagnosis of MDR-TB and Second-Line Antituberculous Drug Susceptibility Testing in Mali (clinicaltrials.gov) - Apr 6, 2018
P, N=34, Terminated, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Phase classification: P=N/A --> P Phase classification: P=N/A --> P | N=340 --> 34
- Trial termination: LUXSOL(TM) Topical Cream for the Treatment of Symptomatic Bacterial Vaginosis; A Proof of Concept Study (clinicaltrials.gov) - Apr 5, 2018
P1, N=50, Terminated, Sponsor: CDA Research Group, Inc.
Phase classification: P=N/A --> P | N=340 --> 34 Suspended --> Terminated; Not for safety reasons
- | Altabax (retapamulin) / GSK, Almirall
Trial completion, Enrollment change: Retapamulin for Reducing MRSA Nasal Carriage (clinicaltrials.gov) - Apr 2, 2018
P4, N=53, Completed, Sponsor: University of California, Irvine
Suspended --> Terminated; Not for safety reasons Active, not recruiting --> Completed | N=150 --> 53
- | Phase classification: Analysis of Lyme Disease Lesions (clinicaltrials.gov) - Mar 30, 2018
P, N=60, Recruiting, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Active, not recruiting --> Completed | N=150 --> 53 Phase classification: P=N/A --> P
- | Trial completion date: TUBOGTEP: Positron Emission Tomography in Extrapulmonary Tuberculosis (clinicaltrials.gov) - Mar 30, 2018
P=N/A, N=55, Completed, Sponsor: Assistance Publique - Hôpitaux de Paris
Phase classification: P=N/A --> P Trial completion date: Dec 2016 --> Mar 2018
- |||| Trial completion, Trial completion date, Trial primary completion date: 10-day Versus 14-day Concomitant PAMC as First-line Treatment Strategy for the Eradication of H. Pylori Infection (clinicaltrials.gov) - Mar 29, 2018
P4, N=364, Completed, Sponsor: Elpen Pharmaceutical Co. Inc.
Trial completion date: Dec 2016 --> Mar 2018 Recruiting --> Completed | Trial completion date: Dec 2018 --> Dec 2017 | Trial primary completion date: Dec 2018 --> Dec 2017
- | Enrollment change, Trial completion date: Tailored Versus Empiric Therapy for Helicobacter Pylori Treatment (clinicaltrials.gov) - Mar 27, 2018
P4, N=322, Recruiting, Sponsor: Shanghai Jiao Tong University School of Medicine
Recruiting --> Completed | Trial completion date: Dec 2018 --> Dec 2017 | Trial primary completion date: Dec 2018 --> Dec 2017 N=500 --> 322 | Trial completion date: Dec 2018 --> May 2018