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127 Companies |
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123 Products |
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123 Products |
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59 Mechanisms of Action |
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6 Trials |
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3245 News |
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- New trial: TROTIC: The Role of Tuberculosis in Chronic Obstructive Lung Disease (clinicaltrials.gov) - May 3, 2016
P=N/A, N=598, Completed, Sponsor: Istanbul Medeniyet University
- cefixime / Generic mfg., azithromycin / Generic mfg.
Enrollment open: Cefixime / Azithromycin pK Study (clinicaltrials.gov) - May 2, 2016
P1, N=8, Recruiting, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Not yet recruiting --> Recruiting
- Trial completion, Enrollment change, Trial primary completion date: Virulence Determinants in S Aureus Bacteremia (clinicaltrials.gov) - Apr 29, 2016
P=N/A, N=1354, Completed, Sponsor: Duke University
Not yet recruiting --> Recruiting Recruiting --> Completed | N=10000 --> 1354 | Trial primary completion date: Dec 2020 --> Aug 2013
- Trial primary completion date: Causes of Fever in Bangladeshi Patients (clinicaltrials.gov) - Apr 28, 2016
P=N/A, N=330, Recruiting, Sponsor: University of Oxford
Recruiting --> Completed | N=10000 --> 1354 | Trial primary completion date: Dec 2020 --> Aug 2013 Trial primary completion date: Oct 2015 --> Dec 2016
- Enrollment open: The Diagnostic Validity of the Urea Breath Test (clinicaltrials.gov) - Apr 28, 2016
P=N/A, N=1200, Recruiting, Sponsor: Seoul National University Bundang Hospital
Trial primary completion date: Oct 2015 --> Dec 2016 Not yet recruiting --> Recruiting
- Trial primary completion date: Peristeen Bowel Irrigation System in Cauda Equina (clinicaltrials.gov) - Apr 28, 2016
P=N/A, N=15, Active, not recruiting, Sponsor: University of Manitoba
Not yet recruiting --> Recruiting Trial primary completion date: Dec 2016 --> Apr 2016
- || New P3 trial, Surgery: ORAL-ISO: Effect of Oral Preparation on Bacterial Colonization of the Pharyngeal Mucosa in Surgery of Head and Neck Cancer (clinicaltrials.gov) - Apr 27, 2016
P3, N=80, Not yet recruiting, Sponsor: Rennes University Hospital
- ||| New P1 trial: A Study to Evaluate Safety, Tolerability and Pharmacokinetics of Ascending Intravenous Single Dose and Repeat Dose of GSK3342830 (clinicaltrials.gov) - Apr 26, 2016
P1, N=78, Not yet recruiting, Sponsor: GlaxoSmithKline
- Trial primary completion date: Pathogenesis of Bacterial Vaginosis in Women Who Have Sex With Women (clinicaltrials.gov) - Apr 26, 2016
P=N/A, N=200, Enrolling by invitation, Sponsor: University of Alabama at Birmingham
Trial primary completion date: Dec 2016 --> Apr 2016 Trial primary completion date: Dec 2017 --> Dec 2018
- zoliflodacin (ETX0914) / Entasis Therap, Global Antibiotic Research and Development Partnership
Trial completion: Randomized, Open-label Phase 2 Study of Oral AZD0914 in the Treatment of Gonorrhea (clinicaltrials.gov) - Apr 26, 2016
P2, N=180, Completed, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Trial primary completion date: Dec 2017 --> Dec 2018 Active, not recruiting --> Completed
- ||| Trial completion: Assessing Contacts' Decision Making on Reducing the Risk of Pertussis Transmission to Newborns Through Immunisation (clinicaltrials.gov) - Apr 26, 2016
P=N/A, N=676, Completed, Sponsor: GlaxoSmithKline
Active, not recruiting --> Completed Recruiting --> Completed
- Clinical: Safety and Efficacy of 5% Monolaurin Vaginal Gel Administered Intravaginally for the Treatment of Bacterial Vaginosis (clinicaltrials.gov) - Apr 25, 2016
P2, N=120, Recruiting, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Recruiting --> Completed Not yet recruiting --> Recruiting
- Trial completion, Surgery: Fluorometholone as Ancillary Therapy for TT Surgery (clinicaltrials.gov) - Apr 21, 2016
P=N/A, N=154, Completed, Sponsor: University of Pennsylvania
Not yet recruiting --> Recruiting Recruiting --> Completed
- Trial completion, Nontuberculous mycobacteria: Diagnostic Accuracy of Nontuberculous Mycobacterial Lung Disease Based on Chest CT (clinicaltrials.gov) - Apr 20, 2016
P=N/A, N=132, Completed, Sponsor: Seoul National University Hospital
Recruiting --> Completed Active, not recruiting --> Completed
- New trial: Effect of a Yoghurt Containing Four Probiotic Lactobacillus Strains on Bacterial Vaginosis (clinicaltrials.gov) - Apr 20, 2016
P=N/A, N=216, Recruiting, Sponsor: Clinical Research Center Kiel GmbH
- Clinical: Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness: A Pilot RCT (clinicaltrials.gov) - Apr 19, 2016
P=N/A, N=115, Recruiting, Sponsor: Sunnybrook Health Sciences Centre
Active, not recruiting --> Completed Trial primary completion date: Oct 2015 --> Oct 2016
- New P3 trial: Photodisinfection for the Decolonization of Staphylococcus Aureus in Hemodialysis Patients (clinicaltrials.gov) - Apr 19, 2016
P3, N=30, Not yet recruiting, Sponsor: McMaster University
- | Shanchol (oral cholera vaccine) / Sanofi
New P2 trial, Head-to-Head: Safety and Immunogenicity of Locally Manufactured Oral Cholera Vaccine (clinicaltrials.gov) - Apr 19, 2016
P2, N=2052, Not yet recruiting, Sponsor: International Centre for Diarrhoeal Disease Research, Bangladesh
- |||| Zemdri (plazomicin) / Ionis, Achaogen
Trial primary completion date: EPIC: A Study of Plazomicin Compared With Meropenem for the Treatment of Complicated Urinary Tract Infection (cUTI) Including Acute Pyelonephritis (AP) (clinicaltrials.gov) - Apr 19, 2016
P3, N=530, Recruiting, Sponsor: Achaogen, Inc.
Trial primary completion date: Oct 2015 --> Oct 2016 Trial primary completion date: May 2017 --> Jan 2017
- Enrollment change: HUC-PHIN: Hub Cleansing to Prevent Hub Infection (clinicaltrials.gov) - Apr 18, 2016
P=N/A, N=149, Completed, Sponsor: Rush University Medical Center
Trial primary completion date: May 2017 --> Jan 2017 N=509 --> 149
- New trial: ALSIBDT: A Multicenter Study to Evaluate a Borrelia Diagnostic Test in Subjects With Early Stage or Late Stage Lyme Disease (clinicaltrials.gov) - Apr 18, 2016
P=N/A, N=300, Not yet recruiting, Sponsor: Advanced Laboratory Services, Inc.
- Enrollment open: FemCure: Transmission of Genital and Extra-genital Chlamydia Trachomatis Infections in Women (clinicaltrials.gov) - Apr 18, 2016
P=N/A, N=400, Recruiting, Sponsor: Maastricht University Medical Center
N=509 --> 149 Not yet recruiting --> Recruiting
- Solithera (solithromycin) / Melinta Therap, Fujifilm Holdings
Trial primary completion date: Genitourinary and Pharyngeal Pharmacokinetics of Solithromycin (clinicaltrials.gov) - Apr 18, 2016
P1, N=28, Recruiting, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Not yet recruiting --> Recruiting Trial primary completion date: Dec 2015 --> Sep 2016
- Cubicin (daptomycin) / Merck (MSD)
Enrollment change, Trial termination: Vancomycin Versus Daptomycin for the Treatment of Methicillin Resistant Staphylococcus Aureus (MRSA) Bacteremia (clinicaltrials.gov) - Apr 15, 2016
P2b, N=14, Terminated, Sponsor: Singapore General Hospital
Trial primary completion date: Dec 2015 --> Sep 2016 N=50 --> 14 | Recruiting --> Terminated; slow accrual of participants
- Trial completion, Enrollment change: Immunopathogenesis of Chlamydia (clinicaltrials.gov) - Apr 15, 2016
P=N/A, N=29, Completed, Sponsor: Arkansas Children's Hospital Research Institute
N=50 --> 14 | Recruiting --> Terminated; slow accrual of participants Enrolling by invitation --> Completed | N=300 --> 29
- Enrollment change: Chlamydia Trachomatis Persistence in the Female Gastrointestinal Tract (clinicaltrials.gov) - Apr 14, 2016
P=N/A, N=0, Withdrawn, Sponsor: Arkansas Children's Hospital Research Institute
Enrolling by invitation --> Completed | N=300 --> 29 N=300 --> 0
- New trial: Structural and Functional Repercussions of Pulmonary Tuberculosis Sequelae (clinicaltrials.gov) - Apr 13, 2016
P=N/A, N=80, Not yet recruiting, Sponsor: Federal University of Uberlandia
- Trial primary completion date: Screening for TB in Pregnancy. on HIV-Infected Pregnant Women (clinicaltrials.gov) - Apr 12, 2016
P=N/A, N=2000, Recruiting, Sponsor: Johns Hopkins University
N=300 --> 0 Trial primary completion date: May 2016 --> Sep 2016
- | Trial completion: Persistence of Protective Antibody Titers 12-24 Months After NmVac4-A/C/Y/W-135-DT Vaccination: Follow Up Study (clinicaltrials.gov) - Apr 12, 2016
P=N/A, N=50, Completed, Sponsor: JN-International Medical Corporation
Trial primary completion date: May 2016 --> Sep 2016 Enrolling by invitation --> Completed
- Trial primary completion date: Ultralow Dose Computed Tomography in High-risk Drug-resistant Tuberculosis Contacts (clinicaltrials.gov) - Apr 9, 2016
P=N/A, N=6, Active, not recruiting, Sponsor: Seoul National University Hospital
Enrolling by invitation --> Completed Trial primary completion date: Feb 2016 --> May 2016
- rifampicin / Generic mfg.
Clinical: Randomized Clinical Trial Comparing 4RIF vs. 9INH for LTBI Treatment-effectiveness (clinicaltrials.gov) - Apr 9, 2016
P3, N=5720, Active, not recruiting, Sponsor: McGill University
Trial primary completion date: Feb 2016 --> May 2016 Trial primary completion date: Feb 2016 --> May 2017
- PREVNAR 13 (pneumococcal 13-valent conjugate vaccine) / Pfizer
Trial completion: A Phase IIb, Open-Label, Dose Ranging Study of 13-Valent Pneumococcal Conjugate Vaccine in Adults 55 Through 74 Years of Age Previously Vaccinated With 23-Valent Pneumococcal Polysaccharide Vaccine (clinicaltrials.gov) - Apr 9, 2016
P2b, N=884, Completed, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Trial primary completion date: Feb 2016 --> May 2017 Active, not recruiting --> Completed
- | rifampicin / Generic mfg.
Trial completion: Rifampin Versus Isoniazid for the Treatment of Latent Tuberculosis Infection in Children (P4v9) (clinicaltrials.gov) - Apr 9, 2016
P3, N=844, Completed, Sponsor: McGill University
Active, not recruiting --> Completed Active, not recruiting --> Completed
- exeporfinium chloride (XF-73) / Destiny Pharma
Trial completion, Trial primary completion date: Study of the Safety and Local Tolerability of Intranasal Gel Formulations of XF-73 (clinicaltrials.gov) - Apr 8, 2016
P1, N=48, Completed, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Active, not recruiting --> Completed Recruiting --> Completed | Trial primary completion date: May 2015 --> Aug 2015
- Trial primary completion date: Validity of Patient-Collected Wet Mounts (clinicaltrials.gov) - Apr 8, 2016
P=N/A, N=40, Recruiting, Sponsor: The University of Texas Health Science Center at San Antonio
Recruiting --> Completed | Trial primary completion date: May 2015 --> Aug 2015 Trial primary completion date: Jan 2016 --> Jul 2016
- | New P4 trial: Clarithromycin Triple Therapy Plus Bismuth for Helicobacter Pylori First-line Treatment (clinicaltrials.gov) - Apr 8, 2016
P4, N=393, Not yet recruiting, Sponsor: Shanghai Jiao Tong University School of Medicine
- ||||| Nuzyra (omadacycline) / Paratek
Enrollment closed, Trial primary completion date: Omadacycline Versus Linezolid for the Treatment of ABSSSI (EudraCT #2013-003644-23) (clinicaltrials.gov) - Apr 7, 2016
P3, N=650, Active, not recruiting, Sponsor: Paratek Pharmaceuticals Inc
Trial primary completion date: Jan 2016 --> Jul 2016 Recruiting --> Active, not recruiting | Trial primary completion date: Oct 2016 --> Apr 2016
- Trial completion: Immune Response of Patients With Chronic, Staphylococcus Aureus-infected Wounds (clinicaltrials.gov) - Apr 7, 2016
P=N/A, N=69, Completed, Sponsor: Centre Hospitalier Universitaire de Nīmes
Recruiting --> Active, not recruiting | Trial primary completion date: Oct 2016 --> Apr 2016 Active, not recruiting --> Completed
- Vabomere (meropenem/vaborbactam) / Melinta Therap
Trial primary completion date: Efficacy, Safety, Tolerability of Vabomere Compared to Best Available Therapy in Treating Serious Infections in Adults (clinicaltrials.gov) - Apr 7, 2016
P3, N=150, Recruiting, Sponsor: Rempex Pharmaceuticals (a wholly owned subsidiary of The Medicines Company)
Active, not recruiting --> Completed Trial primary completion date: Jan 2016 --> Dec 2016
- Trial completion: Rheumatic Heart Disease in Peru: Prevalence and Cardiovascular Outcomes Among Schoolchildren (clinicaltrials.gov) - Apr 7, 2016
P=N/A, N=1023, Completed, Sponsor: University Hospital Inselspital, Berne
Trial primary completion date: Jan 2016 --> Dec 2016 Active, not recruiting --> Completed
- |||||| Solithera (solithromycin) / Melinta Therap, Fujifilm Holdings
Enrollment open, Trial initiation date: Safety and Efficacy of Solithromycin in Adolescents and Children With Community-Acquired Bacterial Pneumonia (clinicaltrials.gov) - Apr 6, 2016
P2/3, N=400, Recruiting, Sponsor: Cempra Inc
Active, not recruiting --> Completed Not yet recruiting --> Recruiting | Initiation date: Dec 2015 --> Mar 2016
- New trial, HEOR, Real-world evidence, Real-world: Effect of Xpert MTB/RIF on Patient Outcomes (clinicaltrials.gov) - Apr 6, 2016
P=N/A, N=892, Recruiting, Sponsor: University of North Carolina, Chapel Hill
- ||||| MTBVAC / Zendal Group
New P1/2 trial, IO biomarker: MTBVAC-Ph1b: Dose-escalation Safety and Immunogenicity Study to Compare MTBVAC to BCG in Newborns With a Safety Arm in Adults (clinicaltrials.gov) - Apr 6, 2016
P1/2, N=54, Recruiting, Sponsor: Biofabri, S.L
- Trial primary completion date: Peristeen Bowel Irrigation System in Cauda Equina (clinicaltrials.gov) - Apr 4, 2016
P=N/A, N=15, Active, not recruiting, Sponsor: University of Manitoba
Not yet recruiting --> Recruiting | Initiation date: Dec 2015 --> Mar 2016 Trial primary completion date: Dec 2015 --> Dec 2016
- New trial: Lock and Key: Host-pathogen Interactions in Meningococcal Disease: Finding the Key That Fits the Lock (clinicaltrials.gov) - Apr 4, 2016
P=N/A, N=300, Not yet recruiting, Sponsor: Public Health England
- rifampicin/isoniazid/ethambutol/pyrazinamide / Generic mfg.
Trial completion: Essentiality of INH in TB Therapy (clinicaltrials.gov) - Apr 1, 2016
P2, N=69, Completed, Sponsor: AIDS Clinical Trials Group
Trial primary completion date: Dec 2015 --> Dec 2016 Active, not recruiting --> Completed
- Trial initiation date: Evaluation of the Practice of Three Morning Sputa on Separate Days for Diagnosis of Mtb (clinicaltrials.gov) - Apr 1, 2016
P=N/A, N=10, Completed, Sponsor: New York University School of Medicine
Active, not recruiting --> Completed Initiation date: Nov 2006 --> Jan 2006
- ||||||| Trial completion: Confirmatory Phase II/III Study Assessing Efficacy, Immunogenicity and Safety of IC43 (clinicaltrials.gov) - Apr 1, 2016
P2/3, N=803, Completed, Sponsor: Valneva Austria GmbH
Initiation date: Nov 2006 --> Jan 2006 Active, not recruiting --> Completed
- aztreonam / Generic mfg., vancomycin / Generic mfg., ceftaroline fosamil / Generic mfg.
Enrollment change: Evaluation of Ceftaroline Fosamil vs Vancomycin Plus Aztreonam in the Treatment of Patients With Skin Infections. (clinicaltrials.gov) - Mar 31, 2016
P3, N=4, Terminated, Sponsor: AstraZeneca
Active, not recruiting --> Completed N=60 --> 4
- | ciprofloxacin oral / Generic mfg.
New P4 trial: Ciprofloxacin for the Prevention of Meningococcal Meningitis (clinicaltrials.gov) - Mar 31, 2016
P4, N=300, Not yet recruiting, Sponsor: Epicentre