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127 Companies |
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123 Products |
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123 Products |
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59 Mechanisms of Action |
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6 Trials |
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3245 News |
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- ||| New P1 trial: SF2a-TT15 Conjugate Vaccine in Healthy Adult Volunteers (clinicaltrials.gov) - Jun 13, 2016
P1, N=64, Not yet recruiting, Sponsor: Institut Pasteur
- | Trial completion: Preventive Therapy for Tuberculosis in HIV Infected Persons (clinicaltrials.gov) - Jun 11, 2016
P3, N=650, Completed, Sponsor: Tuberculosis Research Centre, India
Active, not recruiting --> Completed
- ||| New trial: Clinical Evaluation of the Aptima® Combo 2® Assay Using the Panther® System in Female Urine Samples (clinicaltrials.gov) - Jun 11, 2016
P=N/A, N=2630, Not yet recruiting, Sponsor: Hologic, Inc.
- Trial completion, Trial primary completion date: Evaluation in the Treatment of Nosocomial Sepsis Comparing Polymerase Chain Reaction With Conventional Blood Culture. (clinicaltrials.gov) - Jun 10, 2016
P4, N=200, Completed, Sponsor: Instituto do Coracao
Active, not recruiting --> Completed Recruiting --> Completed | Trial primary completion date: Dec 2014 --> May 2016
- Enrollment closed: A Blinded, Cross-sectional, Diagnostic Evaluation Study Performed in Pulmonary TB Suspects at the TB Dispensary for Sector 4 of the Marius-Nasta-Institute in Bucharest, Romania (clinicaltrials.gov) - Jun 10, 2016
P=N/A, N=400, Active, not recruiting, Sponsor: Michael Hoelscher
Recruiting --> Completed | Trial primary completion date: Dec 2014 --> May 2016 Recruiting --> Active, not recruiting
- Enrollment closed, Trial primary completion date, FDG PET: TEPvENDO: 18-FDG PET/CT Imaging and Clinical Decisions in Infective Endocarditis (clinicaltrials.gov) - Jun 10, 2016
P=N/A, N=150, Active, not recruiting, Sponsor: Assistance Publique - Hôpitaux de Paris
Recruiting --> Active, not recruiting Recruiting --> Active, not recruiting | Trial primary completion date: Feb 2017 --> Oct 2016
- Mycobutin (rifabutin) / Pfizer, Lupin, Isentress (raltegravir) / Merck (MSD)
Enrollment closed, Phase classification, Enrollment change, Trial primary completion date: Rifampin-Based Tuberculosis Treatment Versus Rifabutin-Based Tuberculosis Treatment in Persons With HIV (clinicaltrials.gov) - Jun 10, 2016
P2b, N=71, Active, not recruiting, Sponsor: AIDS Clinical Trials Group
Recruiting --> Active, not recruiting | Trial primary completion date: Feb 2017 --> Oct 2016 Recruiting --> Active, not recruiting | Phase classification: P2 --> P2b | N=471 --> 71 | Trial primary completion date: Sep 2016 --> Feb 2016
- Trial completion: Ultralow Dose Computed Tomography in High-risk Drug-resistant Tuberculosis Contacts (clinicaltrials.gov) - Jun 10, 2016
P=N/A, N=6, Completed, Sponsor: Seoul National University Hospital
Recruiting --> Active, not recruiting | Phase classification: P2 --> P2b | N=471 --> 71 | Trial primary completion date: Sep 2016 --> Feb 2016 Active, not recruiting --> Completed
- |||| Menactra (Meningococcal-groups A, C, Y and W-135 polysaccharide diphtheria toxoid conjugate vaccine) / Sanofi
Enrollment open, Trial primary completion date: Safety of a Meningococcal (Groups A, C, Y and W-135) Polysaccharide Diphtheria Toxoid Conjugate Vaccine in Healthy Subjects in Vietnam (clinicaltrials.gov) - Jun 9, 2016
P2, N=224, Recruiting, Sponsor: Sanofi Pasteur, a Sanofi Company
Active, not recruiting --> Completed Not yet recruiting --> Recruiting | Trial primary completion date: Nov 2016 --> Apr 2017
- Trial completion: SOVS-CTG: Self-Obtained Vaginal Swabs for Chlamydia and Gonorrhea Testing (clinicaltrials.gov) - Jun 5, 2016
P=N/A, N=3500, Completed, Sponsor: University of California, San Francisco
Not yet recruiting --> Recruiting | Trial primary completion date: Nov 2016 --> Apr 2017 Active, not recruiting --> Completed
- | New P4 trial: Comparison of a TauroLock™ Based Regimen to 4% Citrate as Lock Solution in Tunneled Haemodialysis Catheters for the Prevention of Bacteraemia and Dysfunction (clinicaltrials.gov) - Jun 4, 2016
P4, N=100, Recruiting, Sponsor: Medical University of Vienna
- colistin sulphate / Generic mfg.
Trial completion, Enrollment change, Trial primary completion date, Gram negative: Multicentric Study About the Usefulness of Monitoring Plasma Levels of Colistin and Sodium Colistimethate in Patients With Infections Due to Multi-drug Resistant Gram Negative Bacilli, Treated With Colistin (clinicaltrials.gov) - Jun 2, 2016
P=N/A, N=101, Completed, Sponsor: Parc de Salut Mar
Active, not recruiting --> Completed Recruiting --> Completed | N=142 --> 101 | Trial primary completion date: Dec 2013 --> Jan 2015
- New trial: EPICAD: Procalcitonin in Early Antibiotic Interruption in Patient With Bacterial Pulmonary infeCtion and Acute Heart Failure (clinicaltrials.gov) - Jun 1, 2016
P=N/A, N=100, Recruiting, Sponsor: University of Sao Paulo General Hospital
- CTH522 / Statens Serum Institut, Imperial College London
New P1 trial: Safety of Chlamydia Vaccine CTH522 in Healthy Women Aged 18 to 45 Years (clinicaltrials.gov) - Jun 1, 2016
P1, N=35, Not yet recruiting, Sponsor: Statens Serum Institut
- |||| Trial completion: OPTIMIST: QuantiFERON®-TB Gold In-Tube for the Diagnosis of Tuberculosis Infection in Contact Tracing Study. (clinicaltrials.gov) - May 28, 2016
P4, N=871, Completed, Sponsor: Hospital Universitari de Bellvitge
Recruiting --> Completed | N=142 --> 101 | Trial primary completion date: Dec 2013 --> Jan 2015 Active, not recruiting --> Completed
- |||| GEN-004 / Genocea
Trial completion: Safety, Tolerability, and Efficacy Study of Prophylactic S. Pneumoniae Vaccine Following Challenge With S. Pneumoniae (clinicaltrials.gov) - May 27, 2016
P2, N=98, Completed, Sponsor: Genocea Biosciences, Inc.
Active, not recruiting --> Completed Active, not recruiting --> Completed
- Enrollment open: ALSIBDT: A Multicenter Study to Evaluate a Borrelia Diagnostic Test in Subjects With Early Stage or Late Stage Lyme Disease (clinicaltrials.gov) - May 27, 2016
P=N/A, N=300, Recruiting, Sponsor: Advanced Laboratory Services, Inc.
Active, not recruiting --> Completed Not yet recruiting --> Recruiting
- | Enrollment open, Surgery: ORAL-ISO: Effect of Oral Preparation on Bacterial Colonization of the Pharyngeal Mucosa in Surgery of Head and Neck Cancer (clinicaltrials.gov) - May 26, 2016
P3, N=80, Recruiting, Sponsor: Rennes University Hospital
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- Trial initiation date, Trial primary completion date: A Study of the Safety and Immune Response of 2 Doses of a New Shigella Vaccine in Kenyan Adults (clinicaltrials.gov) - May 25, 2016
P2, N=72, Not yet recruiting, Sponsor: GSK Vaccines Institute For Global Health S.r.l.
Not yet recruiting --> Recruiting Initiation date: Apr 2016 --> Jul 2016 | Trial primary completion date: Aug 2016 --> Dec 2016
- Enrollment open, Surgery: SREENSTAPH2: Study of Staphylococcus Aureus Colonization of the Posterior Nasal Cavity in Patients Undergoing Otorhinolaryngologic Surgery (clinicaltrials.gov) - May 25, 2016
P=N/A, N=160, Recruiting, Sponsor: Centre Hospitalier Universitaire de Saint Etienne
Initiation date: Apr 2016 --> Jul 2016 | Trial primary completion date: Aug 2016 --> Dec 2016 Not yet recruiting --> Recruiting
- Trial completion: Safety Study of Live Attenuated Oral Shigella (WRSS1) Vaccine in Bangladeshi Adults and Children (clinicaltrials.gov) - May 25, 2016
P=N/A, N=103, Completed, Sponsor: PATH
Not yet recruiting --> Recruiting Active, not recruiting --> Completed
- triamcinolone acetonide / Generic mfg.
New trial: A Randomized Controlled Trial Evaluating the Efficacy of Intralesional Triamcinolone in Hidradenitis Suppurativa. (clinicaltrials.gov) - May 24, 2016
P=N/A, N=50, Not yet recruiting, Sponsor: University of North Carolina, Chapel Hill
- New trial: Thermal Imaging of the Lung on a Smartphone to Differentiate Bacterial From Non Bacterial Causes of Pneumonia (clinicaltrials.gov) - May 20, 2016
P=N/A, N=250, Not yet recruiting, Sponsor: Massachusetts General Hospital
- New trial: LINEZOLIDE: Pharmacokinetic and Therapeutic Adaptation of Linezolid in the Treatment of Multi-Resistant Tuberculosis (clinicaltrials.gov) - May 20, 2016
P=N/A, N=40, Recruiting, Sponsor: Groupe Hospitalier Paris Saint Joseph
- New trial: Program Cell Death Receptor 1 in Mycobacterium Avium Complex Lung Disease (clinicaltrials.gov) - May 20, 2016
P=N/A, N=170, Recruiting, Sponsor: National Taiwan University Hospital
- New P1 trial: Phase I, Dose Escalation Study to Evaluate the Safety and Pharmacokinetics of NTM-1632 (clinicaltrials.gov) - May 20, 2016
P1, N=24, Not yet recruiting, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
- || Trial primary completion date: RAMPED: Study of Accuracy of New Diagnostic Technology to Determine Guide Rapid Antibiotic Treatment for Serious Infections (clinicaltrials.gov) - May 20, 2016
P=N/A, N=20000, Recruiting, Sponsor: Connie Price
Active, not recruiting --> Completed Trial primary completion date: Nov 2015 --> Nov 2016
- New trial: Resistant Bacterial Infections in the Early Post LDLT Period (clinicaltrials.gov) - May 19, 2016
P=N/A, N=35, Completed, Sponsor: Ain Shams University
- Boostrix (tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccine) / GSK
Enrollment open: Impact of Boostrix™ Maternal Vaccination on Morbidity and Mortality of Pertussis Disease in Infants ≤6 Weeks of Age, in Bogota, Colombia. (clinicaltrials.gov) - May 19, 2016
P=N/A, N=1, Recruiting, Sponsor: GlaxoSmithKline
Trial primary completion date: Nov 2015 --> Nov 2016 Active, not recruiting --> Recruiting
- ||| Trial initiation date, Trial primary completion date: A Phase 2 Trial to Evaluate the Efficacy and Safety of Linezolid in Tuberculosis Patients. (LIN-CL001) (clinicaltrials.gov) - May 18, 2016
P2, N=83, Not yet recruiting, Sponsor: Global Alliance for TB Drug Development
Active, not recruiting --> Recruiting Initiation date: Nov 2014 --> Jul 2016 | Trial primary completion date: Jun 2015 --> Dec 2016
- doxycycline / Generic mfg.
New P2 trial, IO biomarker: Doxycycline in Human Pulmonary Tuberculosis (clinicaltrials.gov) - May 18, 2016
P2, N=40, Recruiting, Sponsor: National University Hospital, Singapore
- Synflorix (10-valent pneumococcal conjugate vaccine) / GSK
Phase classification, Pneumococcal vaccines: Post-marketing Surveillance Study With GSK Biologicals' Pneumococcal Vaccine in Healthy Infants in Philippines (clinicaltrials.gov) - May 17, 2016
P=N/A, N=28, Terminated, Sponsor: GlaxoSmithKline
Initiation date: Nov 2014 --> Jul 2016 | Trial primary completion date: Jun 2015 --> Dec 2016 Phase classification: P4 --> P=N/A
- Trial primary completion date: TANDEM: Pulmonary Tuberculosis Patients With Diabetes Mellitus (clinicaltrials.gov) - May 16, 2016
P=N/A, N=350, Recruiting, Sponsor: Universitas Padjadjaran
Phase classification: P4 --> P=N/A Trial primary completion date: Apr 2016 --> Dec 2016
- | rifampicin / Generic mfg.
Enrollment open, Enrollment change, Trial primary completion date: High-dose Rifampicin for the Treatment of Tuberculous Meningitis: a Dose-finding Study (clinicaltrials.gov) - May 16, 2016
P2/3, N=60, Recruiting, Sponsor: Universitas Padjadjaran
Trial primary completion date: Apr 2016 --> Dec 2016 Active, not recruiting --> Recruiting | N=32 --> 60 | Trial primary completion date: Jun 2016 --> Dec 2016
- aspirin / Generic mfg.
Enrollment closed: A Pilot Study of Adjunctive Aspirin for the Treatment of HIV Negative Adults With Tuberculous Meningitis (clinicaltrials.gov) - May 16, 2016
P2, N=120, Active, not recruiting, Sponsor: Oxford University Clinical Research Unit, Vietnam
Active, not recruiting --> Recruiting | N=32 --> 60 | Trial primary completion date: Jun 2016 --> Dec 2016 Recruiting --> Active, not recruiting
- Enrollment change: A Study to Assess the Pharmacokinetic Profile, the Safety, and the Tolerability of ME1100 Inhalation Solution in Patients With Mechanically Ventilated Bacterial Pneumonia (clinicaltrials.gov) - May 16, 2016
P1, N=40, Recruiting, Sponsor: Meiji Seika Pharma Co., Ltd.
Recruiting --> Active, not recruiting N=50 --> 40
- Xifaxan (rifaximin) / Alfa Wassermann, Bausch Health, Norgine, ASKA Pharma
Trial primary completion date: Efficacy of Rifaximin in Preventing Campylobacteriosis (clinicaltrials.gov) - May 14, 2016
P2/3, N=28, Active, not recruiting, Sponsor: Johns Hopkins Bloomberg School of Public Health
N=50 --> 40 Trial primary completion date: Jun 2015 --> Jun 2016
- mupirocin / Generic mfg.
Trial primary completion date: Prospective Study of Methicillin-Resistant Staphylococcus Aureus (MRSA) Among HIV-Infected Persons (clinicaltrials.gov) - May 13, 2016
P=N/A, N=550, Active, not recruiting, Sponsor: Uniformed Services University of the Health Sciences
Trial primary completion date: Jun 2015 --> Jun 2016 Trial primary completion date: Dec 2015 --> Dec 2016
- Trial completion: Safety Study of ChAdOx1 85A Vaccination With and Without MVA85A Boost in Healthy Adults (clinicaltrials.gov) - May 13, 2016
P1, N=42, Completed, Sponsor: University of Oxford
Trial primary completion date: Dec 2015 --> Dec 2016 Active, not recruiting --> Completed
- Enrollment open, Trial primary completion date: PK Study of Anti-TB Drugs (clinicaltrials.gov) - May 12, 2016
P1, N=60, Recruiting, Sponsor: University of Oxford
Active, not recruiting --> Completed Not yet recruiting --> Recruiting | Trial primary completion date: Jun 2016 --> Dec 2016
- | PA83-FhCMB / iBio
Trial completion: PA83-FhCMB Plant-Derived Recombinant Protective Antigen (rPA) Anthrax Vaccine (clinicaltrials.gov) - May 12, 2016
P1, N=30, Completed, Sponsor: Fraunhofer, Center for Molecular Biotechnology
Not yet recruiting --> Recruiting | Trial primary completion date: Jun 2016 --> Dec 2016 Active, not recruiting --> Completed
- |||| amikacin/fosfomycin inhalation (AFIS) / Savara
Trial completion, Gram negative: Aerosolized Amikacin and Fosfomycin in Mechanically Ventilated Patients With Gram-negative Pneumonia (clinicaltrials.gov) - May 11, 2016
P2, N=150, Completed, Sponsor: Cardeas Pharma
Active, not recruiting --> Completed Active, not recruiting --> Completed
- Cubicin (daptomycin) / Merck (MSD)
Trial primary completion date, Monotherapy: Efficacy of Daptomycin Plus Fosfomycin Versus Daptomycin for Treatment of MRSA Bacteremia (clinicaltrials.gov) - May 10, 2016
P3, N=206, Recruiting, Sponsor: Miquel Pujol
Active, not recruiting --> Completed Trial primary completion date: Dec 2015 --> Dec 2016
- ||||||| Sivextro (tedizolid) / Merck (MSD), Nabriva Therap
Trial completion: Efficacy and Safety of Intravenous to Oral 6-Day Tedizolid Phosphate vs. Intravenous to Oral 10-Day Linezolid in Patients With Acute Bacterial Skin and Skin Structure Infection (ABSSSI) (clinicaltrials.gov) - May 9, 2016
P3, N=598, Completed, Sponsor: Bayer
Trial primary completion date: Dec 2015 --> Dec 2016 Active, not recruiting --> Completed
- Enrollment open: Clarithromycin Triple Therapy Plus Bismuth for Helicobacter Pylori First-line Treatment (clinicaltrials.gov) - May 7, 2016
P4, N=393, Recruiting, Sponsor: Shanghai Jiao Tong University School of Medicine
Active, not recruiting --> Completed Not yet recruiting --> Recruiting
- |||| Trial primary completion date: Clinical Study of Recombinant Mycobacterium Tuberculosis ESAT6-CFP10 Allergen (clinicaltrials.gov) - May 6, 2016
P3, N=1080, Recruiting, Sponsor: Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.
Not yet recruiting --> Recruiting Trial primary completion date: Apr 2016 --> Nov 2016
- || RPA563 / Ligand, recombinant Protective Antigen Anthrax (rPA) vaccine (Px563L) / Ligand
Enrollment closed: A Study of Anthrax Vaccines Px563L and RPA563 in Healthy Adult Subjects (clinicaltrials.gov) - May 4, 2016
P1, N=54, Active, not recruiting, Sponsor: Pfenex, Inc
Trial primary completion date: Apr 2016 --> Nov 2016 Recruiting --> Active, not recruiting
- Enrollment change, Trial withdrawal: Addition of Lactobacillus to Metronidazole in Treatment of CDAD (clinicaltrials.gov) - May 4, 2016
P4, N=0, Withdrawn, Sponsor: VA Medical Center, Houston
Recruiting --> Active, not recruiting N=70 --> 0 | Completed --> Withdrawn
- Trial completion, Enrollment change, Trial primary completion date: Risk Factors for Early Infant Colonization With Methicillin-Resistant Staphylococcus Aureus (clinicaltrials.gov) - May 4, 2016
P=N/A, N=100, Completed, Sponsor: Boston Medical Center
N=70 --> 0 | Completed --> Withdrawn Recruiting --> Completed | N=500 --> 100 | Trial primary completion date: Jan 2012 --> Jun 2012
- mupirocin / Generic mfg.
Trial primary completion date: HOME2DS: Individualized vs. Household MRSA Decolonization (clinicaltrials.gov) - May 3, 2016
P=N/A, N=600, Enrolling by invitation, Sponsor: Washington University School of Medicine
Recruiting --> Completed | N=500 --> 100 | Trial primary completion date: Jan 2012 --> Jun 2012 Trial primary completion date: Jun 2016 --> Jan 2017