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127 Companies |
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123 Products |
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123 Products |
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59 Mechanisms of Action |
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6 Trials |
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3245 News |
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- New trial: PCT_CORDON: Value for Cord Blood Procalcitonin to Diagnose Early Neonatal Bacterial Infection (clinicaltrials.gov) - Aug 8, 2016
P=N/A, N=550, Completed, Sponsor: University Hospital, Montpellier
- Enrollment open: Phase I, Dose Escalation Study to Evaluate the Safety and Pharmacokinetics of NTM-1632 (clinicaltrials.gov) - Aug 8, 2016
P1, N=24, Recruiting, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Not yet recruiting --> Recruiting
- Enrollment open, Enrollment change, Adherence: TXT4MED: Promoting Adherence to Treatment for Latent TB Infection Through Text Messaging (clinicaltrials.gov) - Aug 4, 2016
P=N/A, N=40, Recruiting, Sponsor: University of Arizona
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting | N=250 --> 40
- New trial: coliST131: Epidemiology of ST131 in Besançon University Hospital (clinicaltrials.gov) - Aug 3, 2016
P=N/A, N=300, Recruiting, Sponsor: Centre Hospitalier Universitaire de Besancon
- Trial completion: Intervention in the Management of Post-high Tuberculosis Hospital Through Educational Strategy and Oversight Distance (clinicaltrials.gov) - Aug 3, 2016
P=N/A, N=160, Completed, Sponsor: Hospital de Clinicas de Porto Alegre
Not yet recruiting --> Recruiting | N=250 --> 40 Recruiting --> Completed
- IMM-201 / Immodulon
Trial completion, Nontuberculous mycobacteria: Phase I Trial of DAR-901 (clinicaltrials.gov) - Aug 2, 2016
P1, N=59, Completed, Sponsor: Dartmouth-Hitchcock Medical Center
Recruiting --> Completed Active, not recruiting --> Completed
- New trial: INCREMENT-SOT: Impact of Specific Antimicrobials and MIC Values on the Outcome of Bloodstream Infections Due to ESBL- or Carbapenemase-producing Enterobacterales in Solid Organ Transplantation: an Observational Multinational Study. (clinicaltrials.gov) - Aug 2, 2016
P=N/A, N=400, Active, not recruiting, Sponsor: Spanish Network for Research in Infectious Diseases
- Enrollment open: A Study of a Recombinant Staphylococcus Aureus Vaccine (Escherichia Coli) in Healthy Adults (clinicaltrials.gov) - Jul 30, 2016
P0, N=30, Recruiting, Sponsor: Jiangsu Province Centers for Disease Control and Prevention
Active, not recruiting --> Completed Not yet recruiting --> Recruiting
- ||| Enrollment open: A Study to Evaluate Safety, Tolerability and Pharmacokinetics of Ascending Intravenous Single Dose and Repeat Dose of GSK3342830 (clinicaltrials.gov) - Jul 29, 2016
P1, N=78, Recruiting, Sponsor: GlaxoSmithKline
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- New trial: RNL-MI: The Value of the Neutrophil to Lymphocyte Ratio in the Diagnosis of Bacterial Infections (clinicaltrials.gov) - Jul 28, 2016
P=N/A, N=342, Active, not recruiting, Sponsor: Centre Hospitalier Universitaire, Amiens
- | Trial completion: Pediatrics:Chlamydia, Sickle Cell Anemia and Stroke Risk - Ancillary to STOP II (clinicaltrials.gov) - Jul 27, 2016
P=N/A, N=0, Completed, Sponsor: National Heart, Lung, and Blood Institute (NHLBI)
Not yet recruiting --> Recruiting No longer recruiting --> Completed
- ||| Menveo (meningococcal-groups A, C, W-135 and Y oligosaccharide CRM197 conjugate vaccine) / GSK
Clinical: Safety of One Dose of Meningococcal ACWY Conjugate Vaccine in Subjects From 2 Months to 55 Years of Age in the Republic of South Korea (clinicaltrials.gov) - Jul 25, 2016
P4, N=3960, Recruiting, Sponsor: GlaxoSmithKline
No longer recruiting --> Completed N=3300 --> 3960
- ||| PREVNAR 13 (pneumococcal 13-valent conjugate vaccine) / Pfizer
Trial completion: Post Market Surveillance to Observe Safety of Prevenar13™ in Adults (clinicaltrials.gov) - Jul 24, 2016
P=N/A, N=600, Completed, Sponsor: Pfizer
N=3300 --> 3960 Recruiting --> Completed
- ||| Enrollment change: A Phase 2 Trial to Evaluate the Efficacy and Safety of Linezolid in Tuberculosis Patients. (LIN-CL001) (clinicaltrials.gov) - Jul 20, 2016
P2, N=113, Not yet recruiting, Sponsor: Global Alliance for TB Drug Development
Recruiting --> Completed N=83 --> 113
- Lamprene (clofazimine) / Novartis
Enrollment change: U-MDT: Uniform Multidrug Therapy Regimen for Leprosy Patients (clinicaltrials.gov) - Jul 19, 2016
P4, N=859, Active, not recruiting, Sponsor: University of Brasilia
N=83 --> 113 N=2122 --> 859
- Trial primary completion date: Effect of a Yoghurt Containing Four Probiotic Lactobacillus Strains on Bacterial Vaginosis (clinicaltrials.gov) - Jul 19, 2016
P=N/A, N=216, Recruiting, Sponsor: Clinical Research Center Kiel GmbH
N=2122 --> 859 Trial primary completion date: Apr 2016 --> Jul 2016
- Rotarix (rotavirus vaccine) / GSK
Trial primary completion date: Rota-biome: The Role of the Intestinal Microbiome in Enteric and Systemic Vaccine Immune Responses (clinicaltrials.gov) - Jul 19, 2016
P=N/A, N=63, Recruiting, Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Trial primary completion date: Apr 2016 --> Jul 2016 Trial primary completion date: Sep 2016 --> Dec 2016
- Trial primary completion date: Iron Absorption and Utilization During Tuberculosis and After Treatment (clinicaltrials.gov) - Jul 19, 2016
P=N/A, N=18, Recruiting, Sponsor: Swiss Federal Institute of Technology
Trial primary completion date: Sep 2016 --> Dec 2016 Trial primary completion date: Aug 2016 --> Jan 2017
- vancomycin / Generic mfg.
Trial primary completion date: Bacteremia: Treatment Algorithm to Reduce the Use of Vancomycin in Adults With Blood Stream Infection (clinicaltrials.gov) - Jul 19, 2016
P2, N=500, Recruiting, Sponsor: Duke University
Trial primary completion date: Aug 2016 --> Jan 2017 Trial primary completion date: Jun 2016 --> Apr 2017
- | Cubicin (daptomycin) / Merck (MSD)
Trial termination, Gram positive: Daptomycin for the Treatment of Infections Due to Gram-Positive Bacteria (clinicaltrials.gov) - Jul 19, 2016
P3, N=75, Terminated, Sponsor: Cubist Pharmaceuticals LLC
Trial primary completion date: Jun 2016 --> Apr 2017 Completed --> Terminated; Study terminated due to low enrollment
- Enrollment closed: Safety, Tolerability, and Immunogenicity of the Vaccine Candidates ID93 + AP10-602 and ID93 + GLA-SE Administered Intramuscularly in Healthy Adult Subjects (clinicaltrials.gov) - Jul 18, 2016
P1, N=70, Active, not recruiting, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Completed --> Terminated; Study terminated due to low enrollment Recruiting --> Active, not recruiting
- ||||| ilaprazole / Generic mfg.
New P4 trial: Efficacy and Safety of Ilaprazole Based Bismuth-containing Quadruple Regimen for the First-line Treatment of Helicobacter Pylori Infection (clinicaltrials.gov) - Jul 18, 2016
P4, N=100, Completed, Sponsor: Livzon Pharmaceutical Group Inc.
- New trial: Qnr Genes in Enterobacteriaceae (clinicaltrials.gov) - Jul 15, 2016
P=N/A, N=133, Completed, Sponsor: CHU de Reims
- New trial: Activation of a Cutaneous Inflammasome in the Skin of Hidradenitis Suppurativa Patients (clinicaltrials.gov) - Jul 14, 2016
P=N/A, N=20, Completed, Sponsor: CHU de Reims
- dabigatran etexilate / Generic mfg., argatroban / Generic mfg., enoxaparin sodium / Generic mfg.
Trial completion, Trial primary completion date: Direct Thrombin Inhibitors Versus LMWH in Staphylococcus Aureus Bacteraemia (clinicaltrials.gov) - Jul 14, 2016
P2, N=94, Completed, Sponsor: Universitaire Ziekenhuizen Leuven
Recruiting --> Active, not recruiting Recruiting --> Completed | Trial primary completion date: Jan 2016 --> Apr 2016
- Enrollment change, Trial withdrawal, Endobronchial ultrasound, Biopsy: EBUS-TBNA Versus EBUS-TBNB (clinicaltrials.gov) - Jul 13, 2016
P=N/A, N=0, Withdrawn, Sponsor: Royal Brompton & Harefield NHS Foundation Trust
Recruiting --> Completed | Trial primary completion date: Jan 2016 --> Apr 2016 N=250 --> 0 | Recruiting --> Withdrawn
- ||||||| Nuzyra (omadacycline) / Paratek
Trial completion: Omadacycline Versus Linezolid for the Treatment of ABSSSI (EudraCT #2013-003644-23) (clinicaltrials.gov) - Jul 12, 2016
P3, N=650, Completed, Sponsor: Paratek Pharmaceuticals Inc
N=250 --> 0 | Recruiting --> Withdrawn Active, not recruiting --> Completed
- clindamycin phosphate / Generic mfg.
Trial completion, Trial primary completion date: Clindamycin to Reduce Preterm Birth in a Low Resource Setting (clinicaltrials.gov) - Jul 7, 2016
P4, N=1726, Completed, Sponsor: Christiana Care Health Services
Active, not recruiting --> Completed Active, not recruiting --> Completed | Trial primary completion date: Aug 2015 --> Apr 2016
- Trial completion, Enrollment change: Peristeen Bowel Irrigation System in Cauda Equina (clinicaltrials.gov) - Jul 7, 2016
P=N/A, N=12, Completed, Sponsor: University of Manitoba
Active, not recruiting --> Completed | Trial primary completion date: Aug 2015 --> Apr 2016 Active, not recruiting --> Completed | N=15 --> 12
- | Shanchol (oral cholera vaccine) / Sanofi
New P1/2 trial: Safety and Immunogenicity of Locally Manufactured New (HL-OCV) Oral Cholera Vaccine (clinicaltrials.gov) - Jul 6, 2016
P1/2, N=840, Not yet recruiting, Sponsor: International Centre for Diarrhoeal Disease Research, Bangladesh
- New trial, FDG PET: PET/CT in Extrapulmonary TB in HIV Patients: a Clinical Trial (clinicaltrials.gov) - Jul 5, 2016
P=N/A, N=18, Completed, Sponsor: Centre Hospitalier Universitaire Saint Pierre
- mupirocin / Generic mfg.
Trial completion, Enrollment change: Safety and Efficacy of Mupirocin in Eradicating Colonization With S. Aureus in Critically Ill Infants (clinicaltrials.gov) - Jul 2, 2016
P2, N=155, Completed, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Active, not recruiting --> Completed | N=15 --> 12 Recruiting --> Completed | N=126 --> 155
- New trial: A Study of a Recombinant Staphylococcus Aureus Vaccine (Escherichia Coli) in Healthy Adults (clinicaltrials.gov) - Jul 1, 2016
P0, N=30, Not yet recruiting, Sponsor: Jiangsu Province Centers for Disease Control and Prevention
- etonogestrel/ethinylestradiol intravaginal ring / Generic mfg.
Enrollment open, Trial initiation date: Effects of Contraceptive Ring on Vaginal Microbiota, HIV Shedding and Local Immunity (clinicaltrials.gov) - Jun 29, 2016
P4, N=120, Recruiting, Sponsor: University of Washington
Recruiting --> Completed | N=126 --> 155 Not yet recruiting --> Recruiting | Initiation date: May 2015 --> May 2016
- Trial completion, Enrollment change, Trial primary completion date: Thermal Imaging to Diagnose and Monitor Suspected Bacterial Infections (clinicaltrials.gov) - Jun 29, 2016
P=N/A, N=18, Completed, Sponsor: Massachusetts General Hospital
Not yet recruiting --> Recruiting | Initiation date: May 2015 --> May 2016 Enrolling by invitation --> Completed | N=200 --> 18 | Trial primary completion date: Nov 2016 --> Jun 2016
- triamcinolone acetonide / Generic mfg.
Enrollment open: A Randomized Controlled Trial Evaluating the Efficacy of Intralesional Triamcinolone in Hidradenitis Suppurativa. (clinicaltrials.gov) - Jun 27, 2016
P=N/A, N=50, Recruiting, Sponsor: University of North Carolina, Chapel Hill
Enrolling by invitation --> Completed | N=200 --> 18 | Trial primary completion date: Nov 2016 --> Jun 2016 Not yet recruiting --> Recruiting
- New trial: Staphylokinase and ABO Group Phenotype: New Players in Staphylococcus Aureus Implant-associated Infections Development (clinicaltrials.gov) - Jun 24, 2016
P=N/A, N=88, Completed, Sponsor: Nantes University Hospital
- | Enrollment closed, Enrollment change, Trial primary completion date: Intensive Smoking-cessation Intervention Versus Smoking-cessation Advice in Smear-positive Patients With Pulmonary Tuberculosis (clinicaltrials.gov) - Jun 23, 2016
P3, N=800, Active, not recruiting, Sponsor: All India Institute of Medical Sciences, New Delhi
Not yet recruiting --> Recruiting Recruiting --> Active, not recruiting | N=600 --> 800 | Trial primary completion date: Aug 2015 --> Feb 2016
- Trial primary completion date, Surgery: The Effect of Sodium Bicarbonate on Postoperative Renal Function in Infective Endocarditis Patients Undergoing Open Heart Surgery (clinicaltrials.gov) - Jun 21, 2016
P4, N=70, Recruiting, Sponsor: Yonsei University
Recruiting --> Active, not recruiting | N=600 --> 800 | Trial primary completion date: Aug 2015 --> Feb 2016 Trial primary completion date: Jul 2015 --> Aug 2016
- murepavadin (POL7080) / Spexis
Trial termination, Trial primary completion date: Pharmacokinetics, Safety and Efficacy of POL7080 in Patients With Ventilator Associated Pseudomonas Aeruginosa Pneumonia (clinicaltrials.gov) - Jun 19, 2016
P2, N=25, Terminated, Sponsor: Polyphor Ltd.
Trial primary completion date: Jul 2015 --> Aug 2016 Recruiting --> Terminated | Trial primary completion date: May 2016 --> Dec 2015
- Enrollment open: Thermal Imaging of the Lung on a Smartphone to Differentiate Bacterial From Non Bacterial Causes of Pneumonia (clinicaltrials.gov) - Jun 19, 2016
P=N/A, N=250, Recruiting, Sponsor: Massachusetts General Hospital
Recruiting --> Terminated | Trial primary completion date: May 2016 --> Dec 2015 Not yet recruiting --> Recruiting
- Enrollment closed: Bacterial Meningitis in Adults: Analysis of the Determinants of Mortality and Neurosensory Sequelae (clinicaltrials.gov) - Jun 19, 2016
P=N/A, N=527, Active, not recruiting, Sponsor: Assistance Publique - Hôpitaux de Paris
Not yet recruiting --> Recruiting Recruiting --> Active, not recruiting
- New P1 trial: A Clinical Trial to Evaluate a Recombinant Staphylococcus Aureus Vaccine (Escherichia Coli) in Healthy Adults (clinicaltrials.gov) - Jun 18, 2016
P1, N=144, Not yet recruiting, Sponsor: Jiangsu Province Centers for Disease Control and Prevention
- | clarithromycin / Generic mfg., omeprazole / Generic mfg.
New P1/2 trial: Traditional Chinese Medicine Combined With Standard Triple Region for Eradication of Helicobacter Pylori (clinicaltrials.gov) - Jun 16, 2016
P1/2, N=576, Completed, Sponsor: Xiyuan Hospital of China Academy of Chinese Medical Sciences
- | Minocin for injection (minocycline intravenous) / Melinta Therap
New P1 trial: Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Minocin (Minocycline) for Injection in Healthy Adults (clinicaltrials.gov) - Jun 16, 2016
P1, N=50, Not yet recruiting, Sponsor: Rempex Pharmaceuticals (a wholly owned subsidiary of The Medicines Company)
- Trial completion, Trial primary completion date: Development of a Prediction Model for Differential Diagnosis Between Intestinal Tuberculosis and Crohn's Disease (clinicaltrials.gov) - Jun 16, 2016
P=N/A, N=117, Completed, Sponsor: Asan Medical Center
Recruiting --> Active, not recruiting Recruiting --> Completed | Trial primary completion date: Jul 2014 --> Feb 2015
- New trial: Panton Valentine Leucocidin (clinicaltrials.gov) - Jun 15, 2016
P=N/A, N=324, Recruiting, Sponsor: Hospices Civils de Lyon
- || gepotidacin (GSK2140944) / GSK
Trial primary completion date: A Dose-Ranging Study Evaluating the Efficacy, Safety, and Tolerability of GSK2140944 in the Treatment of Uncomplicated Urogenital Gonorrhea Caused by Neisseria Gonorrhoeae (clinicaltrials.gov) - Jun 14, 2016
P2, N=100, Recruiting, Sponsor: GlaxoSmithKline
Recruiting --> Completed | Trial primary completion date: Jul 2014 --> Feb 2015 Trial primary completion date: Mar 2016 --> Jul 2016
- ||||||| Synflorix (10-valent pneumococcal conjugate vaccine) / GSK
Trial completion: A Study to Compare the Immunogenicity of GSK Biologicals' 10Pn-PD-DiT 4-dose Presentation to the Licensed 1-dose Synflorix™ (10Pn-PD-DiT) Vaccine When Co-administered With DTPw-combination Vaccine in Healthy Infants (clinicaltrials.gov) - Jun 14, 2016
P3, N=320, Completed, Sponsor: GlaxoSmithKline
Trial primary completion date: Mar 2016 --> Jul 2016 Active, not recruiting --> Completed
- ||| New trial: Study of Accuracy of New Diagnostic Technology to Guide Rapid Antibiotic Treatment for Serious Infections (clinicaltrials.gov) - Jun 13, 2016
P=N/A, N=1500, Recruiting, Sponsor: Denver Health and Hospital Authority