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293 Companies |
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490 Products |
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490 Products |
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199 Mechanisms of Action |
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25 Trials |
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7787 News |
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- SAR438544 / Sanofi
Trial primary completion date: A Study to Evaluate Safety, Pharmacokinetics, and Pharmacodynamics of a Single Dose of SAR438544 in Comparison to Glucagon in Type 1 Diabetes Mellitus Patients Under Induced Hypoglycemia (clinicaltrials.gov) - Apr 21, 2016
P1, N=44, Not yet recruiting, Sponsor: Sanofi
Trial primary completion date: Aug 2016 --> Nov 2016
- New trial, Adherence: Check It! Positive Psychology Intervention to Improve Adherence in Adolescents With T1D (clinicaltrials.gov) - Apr 21, 2016
P=N/A, N=120, Completed, Sponsor: Vanderbilt University
- Rituxan (rituximab) / Biogen, Zenyaku Kogyo, Roche
Enrollment change, Trial withdrawal: Incritop: Recombinant Human Interleukin-11 Combination Low-dose Rituximab in Immune Thrombocytopenia (clinicaltrials.gov) - Apr 21, 2016
P=N/A, N=0, Withdrawn, Sponsor: Ming Hou
Trial primary completion date: Aug 2016 --> Nov 2016 N=199 --> 0 | Recruiting --> Withdrawn
- | Rituxan (rituximab) / Biogen, Zenyaku Kogyo, Roche
Trial completion, Enrollment change, Trial primary completion date, Combination therapy: rhTPO Combining Rituximab Versus Low-dose Rituximab in Management of ITP (clinicaltrials.gov) - Apr 21, 2016
P3, N=123, Completed, Sponsor: Shandong University
N=199 --> 0 | Recruiting --> Withdrawn Recruiting --> Completed | N=240 --> 123 | Trial primary completion date: Sep 2013 --> Dec 2013
- | Rituxan (rituximab) / Biogen, Zenyaku Kogyo, Roche
Trial completion, Enrollment change, Trial primary completion date, Combination therapy: Recombinant Human Thrombopoietin in Combination With Rituximab in Immune Thrombocytopenia (ITP) (clinicaltrials.gov) - Apr 21, 2016
P3, N=91, Completed, Sponsor: Ming Hou
Recruiting --> Completed | N=240 --> 123 | Trial primary completion date: Sep 2013 --> Dec 2013 Recruiting --> Completed | N=200 --> 91 | Trial primary completion date: Sep 2012 --> Aug 2013
- Trial primary completion date: Web-based Support During Pregnancy and Early Motherhood in Women With Type 1 Diabetes (MODIAB-web) (clinicaltrials.gov) - Apr 20, 2016
P=N/A, N=160, Recruiting, Sponsor: G
Recruiting --> Completed | N=200 --> 91 | Trial primary completion date: Sep 2012 --> Aug 2013 Trial primary completion date: Mar 2016 --> Dec 2016
- dexamethasone injection / Generic mfg.
Enrollment change, Trial withdrawal: All-Trans Retinoic Acid (ATRA) Combining Dexamethasone Versus High-dose Dexamethasone for Initial Treatment of Primary Immune Thrombocytopenia (ITP) (clinicaltrials.gov) - Apr 20, 2016
P3, N=0, Withdrawn, Sponsor: Shandong University
Trial primary completion date: Mar 2016 --> Dec 2016 N=80 --> 0 | Recruiting --> Withdrawn
- Enrollment change, Trial withdrawal: The Alteration of Macrophage Function in the Spleen Tissues From Patients With Primary Immune Thrombocytopenia (clinicaltrials.gov) - Apr 20, 2016
P=N/A, N=0, Withdrawn, Sponsor: Shandong University
N=80 --> 0 | Recruiting --> Withdrawn N=20 --> 0 | Recruiting --> Withdrawn
- Promacta (eltrombopag) / Novartis
Enrollment change, Trial withdrawal: Alteration of Different Immune Parameters in Immune Thrombocytopenia ?ITP? Patients Receiving Eltrombopag Treatment (clinicaltrials.gov) - Apr 20, 2016
P=N/A, N=0, Withdrawn, Sponsor: Shandong University
N=20 --> 0 | Recruiting --> Withdrawn N=30 --> 0 | Recruiting --> Withdrawn
- Rituxan (rituximab) / Biogen, Zenyaku Kogyo, Roche
Enrollment change, Trial withdrawal: Recombinant Human Thrombopoietin (rhTPO) Combining Rituximab Versus High-dose Dexamethasone for Initial Treatment of Primary Immune Thrombocytopenia (ITP) (clinicaltrials.gov) - Apr 20, 2016
P3, N=0, Withdrawn, Sponsor: Shandong University
N=30 --> 0 | Recruiting --> Withdrawn N=240 --> 0 | Recruiting --> Withdrawn
- volagidemab (REMD-477) / Amgen, REMD Bio
Enrollment open: Single-dose Study to Evaluate Safety, Tolerability, and Pharmacodynamics of REMD-477 in Subjects With Type 1 Diabetes Mellitus (clinicaltrials.gov) - Apr 20, 2016
P1, N=20, Recruiting, Sponsor: REMD Biotherapeutics, Inc.
N=240 --> 0 | Recruiting --> Withdrawn Not yet recruiting --> Recruiting
- | dexamethasone injection / Generic mfg.
Trial completion, Enrollment change, Trial primary completion date: rhTPO Combining Dexamethasone Versus High-dose Dexamethasone for Initial Treatment of ITP (clinicaltrials.gov) - Apr 20, 2016
P3, N=158, Completed, Sponsor: Shandong University
Not yet recruiting --> Recruiting Recruiting --> Completed | N=200 --> 158 | Trial primary completion date: Jul 2013 --> Jul 2014
- Trial completion, Enrollment change: Autoantibody Specificity and Response to IVIG in ITP (clinicaltrials.gov) - Apr 20, 2016
P=N/A, N=672, Completed, Sponsor: Shandong University
Recruiting --> Completed | N=200 --> 158 | Trial primary completion date: Jul 2013 --> Jul 2014 Recruiting --> Completed | N=200 --> 672
- dexamethasone / Generic mfg., prednisone / Generic mfg.
Trial completion, Phase classification, Trial primary completion date: GIMEMA: High-dose Dexamethasone Versus Conventional Dose Prednisone for Initial Treatment of Primary Immune Thrombocytopenia (ITP) (clinicaltrials.gov) - Apr 20, 2016
P4, N=261, Completed, Sponsor: Shandong University
Recruiting --> Completed | N=200 --> 672 Recruiting --> Completed | Phase classification: PN/A --> P4 | Trial primary completion date: Sep 2012 --> May 2014
- |||||||||| Hyrimoz (adalimumab biosimilar) / Novartis
New P3 trial: ADMYRA: Clinical Trial to Compare Treatment With GP2017 and Humira® in Patients With Rheumatoid Arthritis (clinicaltrials.gov) - Apr 20, 2016
P3, N=308, Recruiting, Sponsor: Sandoz
- dexamethasone / Generic mfg.
Enrollment change, Trial withdrawal: Different Cycles of High-dose Dexamethasone for Initial Management of Primary Immune Thrombocytopenia (ITP) (clinicaltrials.gov) - Apr 20, 2016
P4, N=0, Withdrawn, Sponsor: Shandong University
Recruiting --> Completed | Phase classification: PN/A --> P4 | Trial primary completion date: Sep 2012 --> May 2014 N=200 --> 0 | Recruiting --> Withdrawn
- cyclosporin A microemulsion / Generic mfg.
Enrollment change, Trial withdrawal: A Multicenter Investigation of Recombinant Human Thrombopoietin (rhTPO) Combining Cyclosporin A Versus Cyclosporin A in Management of Steroid-Resistant/Relapsed Immune Thrombocytopenia ?ITP? (clinicaltrials.gov) - Apr 20, 2016
P3, N=0, Withdrawn, Sponsor: Shandong University
N=200 --> 0 | Recruiting --> Withdrawn N=120 --> 0 | Recruiting --> Withdrawn
- Rituxan (rituximab) / Biogen, Zenyaku Kogyo, Roche
Enrollment change, Trial withdrawal: A Multicentre Investigation of 2 Cycles Rituximab Compared With Standard Regimen in Management of Steroid-Resistant/Relapsed Immune Thrombocytopenia ?ITP? (clinicaltrials.gov) - Apr 20, 2016
P3, N=0, Withdrawn, Sponsor: Shandong University
N=120 --> 0 | Recruiting --> Withdrawn N=60 --> 0 | Recruiting --> Withdrawn
- dexamethasone / Generic mfg., thalidomide / Generic mfg.
Enrollment change, Trial withdrawal: High-dose Dexamethasone Combining Thalidomide Versus Dexamethasone Mono-therapy for Management of Newly-diagnosed ITP (clinicaltrials.gov) - Apr 20, 2016
P2, N=0, Withdrawn, Sponsor: Shandong University
N=60 --> 0 | Recruiting --> Withdrawn N=240 --> 0 | Recruiting --> Withdrawn
- | dexamethasone / Generic mfg.
Trial completion, Trial initiation date, Trial primary completion date: Caffeic Acid Tablets as a Second-line Therapy for ITP (clinicaltrials.gov) - Apr 20, 2016
P3, N=103, Completed, Sponsor: Shandong University
N=240 --> 0 | Recruiting --> Withdrawn Recruiting --> Completed | Initiation date: Dec 2014 --> Sep 2012 | Trial primary completion date: Mar 2016 --> Dec 2013
- dexamethasone / Generic mfg.
Trial completion: An Investigation of Dexamethasone With Different Doses in the Management of Immune Thrombocytopenia (ITP) (clinicaltrials.gov) - Apr 20, 2016
P2, N=58, Completed, Sponsor: Shandong University
Recruiting --> Completed | Initiation date: Dec 2014 --> Sep 2012 | Trial primary completion date: Mar 2016 --> Dec 2013 Recruiting --> Completed
- Trial completion, Enrollment change: An Investigation of rhTPO With Different Frequencies in the Management of ITP (clinicaltrials.gov) - Apr 20, 2016
P3, N=48, Completed, Sponsor: Shandong University
Recruiting --> Completed Recruiting --> Completed | N=30 --> 48
- |||||||||| AcellBia (rituximab biosimilar) / Biocad, Kocak Farma
New P3 trial: ALTERRA: Clinical Trial to Evaluate Efficacy and Safety of Acellbia (clinicaltrials.gov) - Apr 20, 2016
P3, N=159, Active, not recruiting, Sponsor: Biocad
- Enrollment closed: Virtual Peer-to-Peer (VP2P) Support Mentoring for Juvenile Idiopathic Arthritis (JIA): A Pilot RCT (clinicaltrials.gov) - Apr 20, 2016
P=N/A, N=40, Active, not recruiting, Sponsor: The Hospital for Sick Children
Recruiting --> Completed | N=30 --> 48 Recruiting --> Active, not recruiting
- lansoprazole / Generic mfg., cyclosporine / Generic mfg.
Enrollment change, Trial withdrawal: The Insulin Independence Trial (IIT) Evaluating the Safety and Efficacy of Oral Cyclosporine and Oral Lansoprazole for Insulin Independence Among Patients With Existing Type 1 Diabetes (clinicaltrials.gov) - Apr 19, 2016
P3, N=0, Withdrawn, Sponsor: Perle Bioscience, Inc.
Recruiting --> Active, not recruiting N=60 --> 0 | Not yet recruiting --> Withdrawn
- Enrollment closed, Trial primary completion date: EDIA: Early Dietary Intervention and Later Signs of Beta-Cell Autoimmunity (clinicaltrials.gov) - Apr 19, 2016
P1, N=120, Active, not recruiting, Sponsor: Helsinki University
N=60 --> 0 | Not yet recruiting --> Withdrawn Recruiting --> Active, not recruiting | Trial primary completion date: Mar 2015 --> Jul 2016
- Trial completion: Assessment of an iPhone Application on Glycemic Control in Type 1 Diabetes (clinicaltrials.gov) - Apr 19, 2016
P=N/A, N=92, Completed, Sponsor: The Hospital for Sick Children
Recruiting --> Active, not recruiting | Trial primary completion date: Mar 2015 --> Jul 2016 Active, not recruiting --> Completed
- | Trial completion: Aerobic Exercise and Flu-like Symptoms Following Interferon Beta 1a Injections in Patients With Multiple Sclerosis? (clinicaltrials.gov) - Apr 19, 2016
P=N/A, N=20, Completed, Sponsor: University of Aarhus
Active, not recruiting --> Completed Active, not recruiting --> Completed
- New trial: TWPS: Long-Term Effects of Torso-Weighting (clinicaltrials.gov) - Apr 19, 2016
P=N/A, N=5, Recruiting, Sponsor: San Francisco State University
- Trial primary completion date: Closed-loop Control of Overnight Glucose Levels (Artificial Pancreas) in Type 1 Diab (clinicaltrials.gov) - Apr 19, 2016
P2, N=36, Recruiting, Sponsor: Institut de Recherches Cliniques de Montreal
Active, not recruiting --> Completed Trial primary completion date: Mar 2016 --> Jun 2016
- | intravenous immunoglobulin (IVIG) / Guy's and St Thomas' NHS Foundation Trust
Clinical: STRIVE: A Multicentre randomiSed Controlled TRial of IntraVEnous Immunoglobulin Versus Standard Therapy for Transverse Myelitis (clinicaltrials.gov) - Apr 18, 2016
P3, N=170, Active, not recruiting, Sponsor: Guy's and St Thomas' NHS Foundation Trust
Trial primary completion date: Mar 2016 --> Jun 2016 Recruiting --> Active, not recruiting
- omeprazole / Generic mfg., cyclosporine / Generic mfg.
Enrollment change, Trial withdrawal: The Insulin Independence Trial (IIT) Evaluating the Safety and Efficacy of Oral Cyclosporine and Oral Omeprazole for Insulin Independence Among Recent Onset Type 1 Diabetes Patients (clinicaltrials.gov) - Apr 18, 2016
P2b, N=0, Withdrawn, Sponsor: Perle Bioscience, Inc.
Recruiting --> Active, not recruiting N=81 --> 0 | Not yet recruiting --> Withdrawn
- || Enrollment closed, Enrollment change, Trial primary completion date: BIOFLOW III Asia Registry Orsiro Stent System (clinicaltrials.gov) - Apr 18, 2016
P=N/A, N=364, Active, not recruiting, Sponsor: BIOTRONIK Asia Pacific Pte Ltd
N=81 --> 0 | Not yet recruiting --> Withdrawn Recruiting --> Active, not recruiting | N=880 --> 364 | Trial primary completion date: Sep 2015 --> Apr 2017
- mocravimod (KRP-203) / Priothera
Trial completion, Enrollment change: Safety and Efficacy of KRP203 in Subacute Cutaneous Lupus Erythematosus (clinicaltrials.gov) - Apr 18, 2016
P2, N=10, Completed, Sponsor: Novartis Pharmaceuticals
Recruiting --> Active, not recruiting | N=880 --> 364 | Trial primary completion date: Sep 2015 --> Apr 2017 Terminated --> Completed | N=22 --> 10
- New P1 trial: Safety and Efficacy of Adipose Derived Stem Cells in Refractory Rheumatoid Arthritis, Systemic Lupus Erythematosus or Sharp's Syndrome (clinicaltrials.gov) - Apr 18, 2016
P1, N=20, Recruiting, Sponsor: Arkansas Heart Hospital
- || Zinbryta (daclizumab) / Biogen, AbbVie
Trial primary completion date, Monotherapy: SELECTED: Safety and Efficacy Extension Study of Daclizumab High Yield Process (DAC HYP) (BIIB019) in Participants Who Have Completed Study 205MS202 (NCT00870740) to Treat Relapsing Remitting Multiple Sclerosis (clinicaltrials.gov) - Apr 16, 2016
P2, N=410, Active, not recruiting, Sponsor: Biogen
Terminated --> Completed | N=22 --> 10 Trial primary completion date: Nov 2016 --> Aug 2016
- ||| Trial completion: Study of Electrical Impedance Myography (EIM) in ALS (clinicaltrials.gov) - Apr 16, 2016
P=N/A, N=120, Completed, Sponsor: Skulpt, Inc.
Trial primary completion date: Nov 2016 --> Aug 2016 Active, not recruiting --> Completed
- |||| opicinumab (BIIB033) / Biogen, Avonex (recombinant IFN-β-1a) / Biogen
Trial completion: SYNERGY: Study to Assess the Efficacy, Safety, Tolerability, and Pharmacokinetics of BIIB033 in Participants With Relapsing Forms of Multiple Sclerosis When Used Concurrently With Avonex (clinicaltrials.gov) - Apr 16, 2016
P2, N=419, Completed, Sponsor: Biogen
Active, not recruiting --> Completed Active, not recruiting --> Completed
- Trial completion, Enrollment change: Fructose and Glucose and TAS1R2 in Type 1 Diabetes (clinicaltrials.gov) - Apr 15, 2016
P=N/A, N=16, Completed, Sponsor: Universidade Federal do Rio de Janeiro
Active, not recruiting --> Completed Active, not recruiting --> Completed | N=30 --> 16
- ||||||| dalfampridine / Generic mfg.
Trial completion: ENHANCE: Efficacy and Safety Study of Prolonged-Release Fampridine in Participants With Multiple Sclerosis (clinicaltrials.gov) - Apr 15, 2016
P3, N=646, Completed, Sponsor: Biogen
Active, not recruiting --> Completed | N=30 --> 16 Active, not recruiting --> Completed
- ||| Yervoy (ipilimumab) / Ono Pharma, BMS
New trial: Study of Autoimmune Disease Complications Following Ipilimumab Treatment Among Melanoma Patients With Underlying Autoimmune Diseases (clinicaltrials.gov) - Apr 15, 2016
P=N/A, N=370, Active, not recruiting, Sponsor: Bristol-Myers Squibb
- | Suglat (ipragliflozin) / EMD Serono, Kotobuki, Astellas
Trial completion: Pharmacodynamics, Pharmacokinetics, and Safety of ASP1941 in Patients With Type 1 Diabetes Mellitus (clinicaltrials.gov) - Apr 15, 2016
P2, N=43, Completed, Sponsor: Astellas Pharma Inc
Active, not recruiting --> Completed Active, not recruiting --> Completed
- | HinsBet (human insulin) / Adocia
New P1/2 trial: A Trial to Investigate Post Prandial Blood Glucose Control With Fast-acting Human Insulin HinsBet (clinicaltrials.gov) - Apr 15, 2016
P1/2, N=36, Not yet recruiting, Sponsor: Adocia
- | Trial completion: The Performance of an Artificial Pancreas at Home in People With Type 1 Diabetes (clinicaltrials.gov) - Apr 14, 2016
P=N/A, N=28, Completed, Sponsor: St Vincent's Hospital Melbourne
Active, not recruiting --> Completed Recruiting --> Completed
- Trial completion, Enrollment change: IPCL: Effect of the InsuPatch on Automated Closed-loop Glucose Control in Type 1 Diabetes (clinicaltrials.gov) - Apr 14, 2016
P0, N=10, Completed, Sponsor: Yale University
Recruiting --> Completed Recruiting --> Completed | N=20 --> 10
- Trial completion, Enrollment change, Trial primary completion date: The Effects of High and Low Blood Glucose Values on the Brain in Children With Type 1 Diabetes Mellitus (clinicaltrials.gov) - Apr 14, 2016
P=N/A, N=43, Completed, Sponsor: Stanford University
Recruiting --> Completed | N=20 --> 10 Active, not recruiting --> Completed | N=100 --> 43 | Trial primary completion date: Dec 2014 --> Dec 2015
- Trial completion, Trial primary completion date: Safety and Efficacy Study of Encapsulated Human Islets Allotransplantation to Treat Type 1 Diabetes (clinicaltrials.gov) - Apr 14, 2016
P1, N=15, Completed, Sponsor: Cliniques universitaires Saint-Luc- Universit
Active, not recruiting --> Completed | N=100 --> 43 | Trial primary completion date: Dec 2014 --> Dec 2015 Recruiting --> Completed | Trial primary completion date: Dec 2013 --> Sep 2015
- Trial completion: Neuropsychological and Neuroanatomical Studies of Young Children With and Without Type 1 Diabetes Mellitus (clinicaltrials.gov) - Apr 14, 2016
P=N/A, N=30, Completed, Sponsor: Stanford University
Recruiting --> Completed | Trial primary completion date: Dec 2013 --> Sep 2015 Active, not recruiting --> Completed
- Trial primary completion date: Power Over Pain (POP) Study (clinicaltrials.gov) - Apr 14, 2016
P=N/A, N=144, Recruiting, Sponsor: University of Washington
Active, not recruiting --> Completed Trial primary completion date: Sep 2016 --> Jan 2017
- New trial, HEOR: Effect of Active-Passive Trainer Cycling on Multiple Sclerosis (clinicaltrials.gov) - Apr 14, 2016
P=N/A, N=30, Not yet recruiting, Sponsor: NHS Greater Glasgow and Clyde