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293 Companies |
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491 Products |
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491 Products |
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198 Mechanisms of Action |
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26 Trials |
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7805 News |
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- | Simponi (golimumab) / Merck (MSD), Mitsubishi Tanabe, J&J
Enrollment closed: A Study of the Safety and Efficacy of CNTO 148 (Golimumab) in Children With Juvenile Idiopathic Arthritis (JIA) and Multiple Joint Involvement Who Have Poor Response to Methotrexate (GO KIDS) (clinicaltrials.gov) - Mar 7, 2013
P3, N=173, Active, not recruiting, Sponsor: Janssen Research & Development, LLC
Recruiting --> Active, not recruiting
- | olesoxime (TRO19622) / Roche
New P1 trial: Safety Study of Olesoxime in Patients With Stable Relapsing Remitting Multiple Sclerosis Treated With Interferon Beta. (clinicaltrials.gov) - Mar 7, 2013
P1, N=44, Active, not recruiting, Sponsor: Trophos
- GSK2618960 / GSK
New P1 trial: A First Time in Human Study Exploring Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of GSK2618960 in Healthy Volunteers and Patients With Relapsing Remitting Multiple Sclerosis (RRMS) (clinicaltrials.gov) - Mar 7, 2013
P1, N=16, Terminated, Sponsor: GlaxoSmithKline
- || dalfampridine / Generic mfg.
Trial completion: Open Label Extension Study to Evaluate the Safety and Tolerability of Oral Fampridine-Sustained Release (SR) in Canadian Participants With Multiple Sclerosis Who Participated in Acorda Extension Trials. (clinicaltrials.gov) - Mar 6, 2013
P3, N=38, Completed, Sponsor: Biogen Idec
Recruiting --> Active, not recruiting Active, not recruiting --> Completed
- Cimzia (certolizumab pegol) / Astellas, UCB
Trial completion, Combination therapy, Patient reported outcomes: PICS: The Effect of Certolizumab Pegol on MRI Synovitis and Bone Edema in Rheumatoid Arthritis Patients (clinicaltrials.gov) - Mar 6, 2013
P3, N=20, Completed, Sponsor: Oklahoma Medical Research Foundation
Active, not recruiting --> Completed Not yet recruiting --> Completed
- New P4 trial, IO biomarker: Consequences of Anti-interleukin 6 Immunotherapy Treatment for Rheumatoid Arthritis on Periodontium (clinicaltrials.gov) - Mar 6, 2013
P4, N=47, Recruiting, Sponsor: Nantes University Hospital
- ||| Enrollment open: Assessment of the Safety of Adalimumab in Rheumatoid Arthritis Patients Showing Rapid Progression of Structural Damage of the Joints, Who Have no Prior History of Treatment With Disease-modifying Anti-rheumatic Drugs or Biological Agents (clinicaltrials.gov) - Mar 6, 2013
P=N/A, N=150, Recruiting, Sponsor: AbbVie
Not yet recruiting --> Completed Not yet recruiting --> Recruiting
- |||| mavrilimumab (KPL-301) / Kiniksa
Enrollment open: A Study of Mavrilimumab Versus Anti Tumor Necrosis Factor in Subjects With Rheumatoid Arthritis (clinicaltrials.gov) - Mar 6, 2013
P2, N=172, Recruiting, Sponsor: MedImmune LLC
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- Enrollment change, HEOR: Cardiopulmonary Fitness, Lung Function, Muscular Oxygen Saturation, and Quality of Life in T1DM (clinicaltrials.gov) - Mar 5, 2013
P=N/A, N=40, Completed, Sponsor: National Taiwan University Hospital
Not yet recruiting --> Recruiting N=50 --> 40
- ||| Enrollment open, HEOR: INCONTROL: The Effects of RT-CGM on Glycemia and QoL in Patients With T1DM and IHA (clinicaltrials.gov) - Mar 5, 2013
P=N/A, N=52, Recruiting, Sponsor: VU University Medical Center
N=50 --> 40 Not yet recruiting --> Recruiting
- Trial completion, HEOR: Cardiopulmonary Fitness, Lung Function, Muscular Oxygen Saturation, and Quality of Life in T1DM (clinicaltrials.gov) - Mar 5, 2013
P=N/A, N=40, Completed, Sponsor: National Taiwan University Hospital
Not yet recruiting --> Recruiting Recruiting --> Completed
- | relamorelin (RM-131) / AbbVie
Trial completion: Study to Assess Pharmacodynamics of RM-131 in Patients With Diabetic Gastroparesis (clinicaltrials.gov) - Mar 5, 2013
P1, N=20, Completed, Sponsor: Rhythm Pharmaceuticals, Inc.
Recruiting --> Completed Recruiting --> Completed
- Trial termination: Islet Transplantation for Type 1 Diabetes Mellitus (clinicaltrials.gov) - Mar 4, 2013
P1/2, N=2, Terminated, Sponsor: Mayo Clinic
Recruiting --> Completed Completed --> Terminated; The study was terminated early due to difficulty in recruiting subjects, and ran short of funds.
- Trial initiation date: Inpatient Evaluation of the MD-Logic Artificial Pancreas System in Patients With Type 1 Diabetes (clinicaltrials.gov) - Mar 4, 2013
P1, N=25, Not yet recruiting, Sponsor: Rabin Medical Center
Completed --> Terminated; The study was terminated early due to difficulty in recruiting subjects, and ran short of funds. Initiation date: Jan 2013 --> Oct 2013
- |||| Tavalisse (fostamatinib) / Rigel
Trial completion: Study of the Effect of Fostamatinib Twice Daily on Blood Pressure in Patients With Rheumatoid Arthritis (clinicaltrials.gov) - Mar 4, 2013
P2, N=135, Completed, Sponsor: AstraZeneca
Initiation date: Jan 2013 --> Oct 2013 Active, not recruiting --> Completed
- ||||||| Tavalisse (fostamatinib) / Rigel
Trial completion: OSKIRA - 3: Evaluation of Effectiveness of Two Dosing Regimens of Fostamatinib Compared to Placebo in Patients With Rheumatoid Arthritis (RA) Who Are Taking Methotrexate and Have Had Inadequate Response to Single TNF-alpha Antagonist (clinicaltrials.gov) - Mar 4, 2013
P3, N=323, Completed, Sponsor: AstraZeneca
Active, not recruiting --> Completed Active, not recruiting --> Completed
- | Enbrel (etanercept) / Pfizer, Amgen
Trial termination: ENBREL NIS CN: A Study of Rheumatoid Arthritis Treatment With Enbrel in Adult Patient in Outpatient Department (clinicaltrials.gov) - Mar 3, 2013
P4, N=166, Terminated, Sponsor: Pfizer
Active, not recruiting --> Completed Recruiting --> Terminated; See termination reason in detailed description.
- Enrollment open, Adherence: Adherence-SLE: International Prospective Study on Adherence to Treatment in Patients With Active Systemic Lupus Erythematosus (clinicaltrials.gov) - Mar 3, 2013
P=N/A, N=300, Recruiting, Sponsor: Assistance Publique - Hôpitaux de Paris
Recruiting --> Terminated; See termination reason in detailed description. Not yet recruiting --> Recruiting
- | Enrollment closed: A Study of Rabeprazole for Prevention of Non Steroidal Anti-inflammatory Drug -Associated Gastroduodenal Injury (clinicaltrials.gov) - Mar 3, 2013
P3, N=112, Active, not recruiting, Sponsor: Chinese University of Hong Kong
Not yet recruiting --> Recruiting Recruiting --> Active, not recruiting
- Enrollment change: Artificial Pancreas Control System in an Inpatient Setting (clinicaltrials.gov) - Mar 3, 2013
P2, N=12, Active, not recruiting, Sponsor: Legacy Health System
Recruiting --> Active, not recruiting N=10 --> 12
- Enrollment closed: Artificial Pancreas Control System in an Inpatient Setting (clinicaltrials.gov) - Mar 3, 2013
P2, N=12, Active, not recruiting, Sponsor: Legacy Health System
N=10 --> 12 Recruiting --> Active, not recruiting
- GlucaGen (recombinant glucagon) / Novo Nordisk
Trial completion: Physiologic Response to Glucagon at Varying Insulin Levels (clinicaltrials.gov) - Mar 3, 2013
P=N/A, N=12, Completed, Sponsor: Legacy Health System
Recruiting --> Active, not recruiting Active, not recruiting --> Completed
- Enrollment open: SAMSPAP: Sleep Apnea in Multiple Sclerosis Positive Airway Pressure Trial (clinicaltrials.gov) - Mar 2, 2013
P=N/A, N=65, Recruiting, Sponsor: McGill University
Active, not recruiting --> Completed Not yet recruiting --> Recruiting
- Tysabri (natalizumab) / Biogen, Royalty
Enrollment closed: CogMS: Cognitive Evolution in Tysabri Treated Multiple Sclerosis Patients (clinicaltrials.gov) - Feb 28, 2013
P4, N=60, Active, not recruiting, Sponsor: Clinique Neuro-Outaouais
Not yet recruiting --> Recruiting Recruiting --> Active, not recruiting
- ||| rHIgM22 / Acorda
New P1 trial: An Intravenous Infusion Study of rHIgM22 in Patients With Multiple Sclerosis (clinicaltrials.gov) - Feb 28, 2013
P1, N=71, Recruiting, Sponsor: Acorda Therapeutics
- | GSK239512 / GSK
New P1 trial: GSK239512 DDI Study (clinicaltrials.gov) - Feb 28, 2013
P1, N=22, Completed, Sponsor: GlaxoSmithKline
- | Arcalyst (rilonacept) / Regeneron, Kiniksa
New P1 trial: Study to Evaluate the Safety and Tolerability of Two Doses of Rilonacept in Pediatric Subjects With Active Systemic Juvenile Idiopathic Arthritis (SJIA) (clinicaltrials.gov) - Feb 28, 2013
P1, N=24, Completed, Sponsor: Regeneron Pharmaceuticals
- | Orencia (abatacept) / BMS
Enrollment closed, MRI: Benefits of Injectable Abatacept Using Magnetic Resonance Imaging (MRI) in Rheumatoid Arthritis (RA) Patients (clinicaltrials.gov) - Feb 28, 2013
P3, N=30, Active, not recruiting, Sponsor: Arthritis & Rheumatic Disease Specialties Research
Recruiting --> Active, not recruiting Recruiting --> Active, not recruiting
- |||| Artlegia (olokizumab) - R / Pharm
Trial completion: Efficacy and Safety of Olokizumab With Rheumatoid Arthritis With Previously Failed to Anti-tumor Necrosis Factor (Anti-TNF) Therapy (clinicaltrials.gov) - Feb 28, 2013
P2, N=119, Completed, Sponsor: UCB Japan Co. Ltd.
Recruiting --> Active, not recruiting Active, not recruiting --> Completed
- amiloride hydrochloride / Generic mfg.
New P2 trial: ACTION: Amiloride Clinical Trial In Optic Neuritis (clinicaltrials.gov) - Feb 27, 2013
P2, N=46, Recruiting, Sponsor: University of Oxford
- |||| amiselimod (MT 1303) / Mitsubishi Tanabe, Bausch Health
Enrollment open: Dose-finding Study of MT-1303 (clinicaltrials.gov) - Feb 27, 2013
P2, N=400, Recruiting, Sponsor: Mitsubishi Tanabe Pharma Corporation
Active, not recruiting --> Completed Not yet recruiting --> Recruiting
- Enrollment change: Teleconference Fatigue Management for People With Multiple Sclerosis (clinicaltrials.gov) - Feb 26, 2013
P=N/A, N=190, Completed, Sponsor: University of Illinois at Chicago
Not yet recruiting --> Recruiting N=140 --> 190
- Trial completion: Teleconference Fatigue Management for People With Multiple Sclerosis (clinicaltrials.gov) - Feb 26, 2013
P=N/A, N=190, Completed, Sponsor: University of Illinois at Chicago
N=140 --> 190 Recruiting --> Completed
- |||| Humira (adalimumab) / AbbVie
Trial completion: A Study to Determine the Effect of Methotrexate (MTX) Dose on Clinical Outcome and Ultrasonographic Signs in Subjects With Moderately to Severely Active Rheumatoid Arthritis (RA) Treated With Adalimumab (MUSICA) (clinicaltrials.gov) - Feb 26, 2013
P4, N=308, Completed, Sponsor: AbbVie (prior sponsor, Abbott)
Recruiting --> Completed Active, not recruiting --> Completed
- Clinical: Power Over Pain (POP) Study (clinicaltrials.gov) - Feb 25, 2013
P=N/A, N=144, Recruiting, Sponsor: University of Washington
- Symlin (pramlintide) / AstraZeneca
Enrollment open: Effect of Different Fixed Pramlintide:Insulin Dose Ratios on Postprandial Glucose in T1DM (clinicaltrials.gov) - Feb 25, 2013
P1, N=20, Recruiting, Sponsor: Amylin Pharmaceuticals, LLC.
Active, not recruiting --> Completed Not yet recruiting --> Recruiting
- l-methylfolate / Generic mfg.
Enrollment closed: Nutrition, Neuromuscular Electrical Stimulation (NMES) and Secondary Progressive Multiple Sclerosis (SPMS) (clinicaltrials.gov) - Feb 25, 2013
P1, N=40, Active, not recruiting, Sponsor: University of Iowa
Not yet recruiting --> Recruiting Recruiting --> Active, not recruiting
- |||| aminopterin / Syntrix
Enrollment open: Aminopterin Dose Finding Treatment for Methotrexate-Naïve Rheumatoid Arthritis (clinicaltrials.gov) - Feb 24, 2013
P2, N=192, Recruiting, Sponsor: Syntrix Biosystems, Inc.
Recruiting --> Active, not recruiting Not yet recruiting --> Recruiting
- || Humira (adalimumab) / Eisai, AbbVie
Enrollment closed: REACH: Real Life Evaluation of Rheumatoid Arthritis in Canadians Taking HUMIRA (clinicaltrials.gov) - Feb 24, 2013
P=N/A, N=1000, Active, not recruiting, Sponsor: AbbVie (prior sponsor, Abbott)
Not yet recruiting --> Recruiting Recruiting --> Active, not recruiting
- Gardasil (quadrivalent human papillomavirus (types 6, 11, 16, 18) recombinant vaccine) / UniQuest
Enrollment open: Study to Determine if Gardasil Vaccine is Safe and Effective in Lupus Patients (clinicaltrials.gov) - Feb 24, 2013
P1, N=40, Recruiting, Sponsor: Wayne State University
Recruiting --> Active, not recruiting Not yet recruiting --> Recruiting
- ||| Rebif (human IFN-β-1a) / EMD Serono
Trial completion, Compliance: An Observational Study for the Assessment of Compliance and Persistence to Rebif® Therapy of Patients With Relapsing-remitting Multiple Sclerosis (MS) and Evaluation of Potential Factors Influencing These Parameters (clinicaltrials.gov) - Feb 21, 2013
P=N/A, N=133, Completed, Sponsor: Merck KGaA
Not yet recruiting --> Recruiting Active, not recruiting --> Completed
- Trial completion: Determining How the Nervous System Processes Pain in Adults With Fibromyalgia (clinicaltrials.gov) - Feb 21, 2013
P=N/A, N=137, Completed, Sponsor: University of Wisconsin, Madison
Active, not recruiting --> Completed Active, not recruiting --> Completed
- ||| Rebif (human IFN-?-1a) / EMD Serono
Trial completion, Adherence: An Observational Study for the Assessment of Adherence, Effectiveness and Convenience of Rebif (clinicaltrials.gov) - Feb 21, 2013
P=N/A, N=912, Completed, Sponsor: Merck KGaA
Active, not recruiting --> Completed Active, not recruiting --> Completed
- ||| Promacta (eltrombopag) / Novartis
Enrollment closed: PETIT: Efficacy and Safety Study of Eltrombopag in Pediatric Patients With Thrombocytopenia From Chronic Idiopathic Thrombocytopenic Purpura (ITP) (clinicaltrials.gov) - Feb 20, 2013
P2, N=70, Active, not recruiting, Sponsor: GlaxoSmithKline
Active, not recruiting --> Completed Recruiting --> Active, not recruiting
- ||||| Betaseron (IFN-β-1b) / Bayer
New P4 trial: BENEFIT 11: Follow-up Study After 11 Years of Patients Who Were Included in the BENEFIT Trial (304747) With a First Demyelinating Event Suggestive of Multiple Sclerosis (clinicaltrials.gov) - Feb 19, 2013
P4, N=400, Recruiting, Sponsor: Bayer
- ||| Trial completion, Compliance, Patient reported outcomes: Impact Of RA Therapy Compliance On Patient-Reported Outcomes (clinicaltrials.gov) - Feb 19, 2013
P=N/A, N=396, Completed, Sponsor: Pfizer
Recruiting --> Active, not recruiting Active, not recruiting --> Completed
- Enrollment change: Effectiveness of a Knowledge-based Intervention for Patients With Cutaneous Lupus Erythematosus (clinicaltrials.gov) - Feb 18, 2013
P=N/A, N=31, Completed, Sponsor: Northwestern University
Active, not recruiting --> Completed N=50 --> 31
- thyroxine / Generic mfg.
Enrollment open: Selenium Supplementation in Pregnancy (clinicaltrials.gov) - Feb 18, 2013
P4, N=150, Recruiting, Sponsor: University of Roma La Sapienza
N=50 --> 31 Not yet recruiting --> Recruiting
- || Rebif (human IFN-β-1a) / EMD Serono
Enrollment closed, Adherence: MEASURE: Treatment Adherence When Using RebiSmart™ in Relapsing Multiple Sclerosis Subjects (clinicaltrials.gov) - Feb 18, 2013
P=N/A, N=188, Active, not recruiting, Sponsor: Merck KGaA
Not yet recruiting --> Recruiting Recruiting --> Active, not recruiting
- Trial completion: Effectiveness of a Knowledge-based Intervention for Patients With Cutaneous Lupus Erythematosus (clinicaltrials.gov) - Feb 18, 2013
P=N/A, N=31, Completed, Sponsor: Northwestern University
Recruiting --> Active, not recruiting Recruiting --> Completed