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248 Companies |
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339 Products |
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339 Products |
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149 Mechanisms of Action |
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22 Trials |
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5600 News |
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- ||| gerilimzumab (ARGX-109) / argenx
Trial initiation date, Trial primary completion date: Study Evaluating Gerilimzumab (clinicaltrials.gov) - Jan 18, 2018
P2, N=200, Not yet recruiting, Sponsor: Bird Rock Bio, Inc.
Initiation date: Nov 2016 --> Jan 2018 | Trial primary completion date: May 2018 --> May 2019
- | Trial primary completion date: The Effect of Puerarin Injection on Carotid Intima-Media Thickness in Patients With Rheumatoid Arthritis (clinicaltrials.gov) - Jan 17, 2018
P2, N=119, Completed, Sponsor: Chengdu PLA General Hospital
Initiation date: Nov 2016 --> Jan 2018 | Trial primary completion date: May 2018 --> May 2019 Trial primary completion date: Nov 2014 --> Sep 2017
- | Enrollment closed, Trial primary completion date: Zushima Plaster for Treating Knee Osteoarthritis (clinicaltrials.gov) - Jan 17, 2018
P4, N=396, Active, not recruiting, Sponsor: Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Trial primary completion date: Nov 2014 --> Sep 2017 Recruiting --> Active, not recruiting | Trial primary completion date: Apr 2017 --> Mar 2018
- | Trial completion, Enrollment change, Surgery: Pressure Ulcers in Knee Replacement Surgery (clinicaltrials.gov) - Jan 17, 2018
P=N/A, N=565, Completed, Sponsor: Istituto Ortopedico Rizzoli
Recruiting --> Active, not recruiting | Trial primary completion date: Apr 2017 --> Mar 2018 Recruiting --> Completed | N=440 --> 565
- || Actemra IV (tocilizumab) / Roche, JW Pharma
Enrollment closed: A Comparative Study to Observe the Effect of Concomitant Use of Corticosteroid Treatment in Rheumatoid Arthritis (RA) Participants Who Are Treated With a Tumor Necrosis Factor (TNF) Inhibitor or Tocilizumab (TCZ) as Their Second Biological Treatment. (clinicaltrials.gov) - Jan 12, 2018
P=N/A, N=200, Active, not recruiting, Sponsor: Hoffmann-La Roche
Recruiting --> Completed | N=440 --> 565 Recruiting --> Active, not recruiting
- || Actemra SC (tocilizumab SC) / Roche, Halozyme
Enrollment closed, Combination therapy, Monotherapy: EMBRACE-SC: Observational Study of Subcutaneous (SC) Tocilizumab Alone or in Combination With Conventional Disease-Modifying Antirheumatic Drugs (cDMARDs) in Rheumatoid Arthritis (clinicaltrials.gov) - Jan 12, 2018
P=N/A, N=200, Active, not recruiting, Sponsor: Hoffmann-La Roche
Recruiting --> Active, not recruiting Recruiting --> Active, not recruiting
- | Trial completion, Enrollment change: Proof of Concept Study of PEMF (Pulsed Electromagnetic Field) Therapy in Subjects With Osteoarthritis of the Knee (clinicaltrials.gov) - Jan 12, 2018
P=N/A, N=19, Completed, Sponsor: Regenesis Biomedical, Inc.
Recruiting --> Active, not recruiting Active, not recruiting --> Completed | N=14 --> 19
- || Actemra IV (tocilizumab) / Roche, JW Pharma, Actemra SC (tocilizumab SC) / Roche, Halozyme
Enrollment closed: CONIFER: Characterization of Non-Steroidal Anti-Inflammatory Drug (NSAID) Intake in Rheumatoid Arthritis (RA) Participants on Tocilizumab (RoACTEMRA (clinicaltrials.gov) - Jan 12, 2018
P=N/A, N=135, Active, not recruiting, Sponsor: Hoffmann-La Roche
Active, not recruiting --> Completed | N=14 --> 19 Recruiting --> Active, not recruiting
- ||| Jyseleca (filgotinib) / Galapagos, Gilead, SOBI
Enrollment closed: EQUATOR: A Study to Assess Efficacy and Safety of Filgotinib in Active Psoriatic Arthritis (clinicaltrials.gov) - Jan 12, 2018
P2, N=131, Active, not recruiting, Sponsor: Galapagos NV
Recruiting --> Active, not recruiting Recruiting --> Active, not recruiting
- | Trial completion: A Comparison of Two Different Surgical Techniques for Total Hip Resurfacing (clinicaltrials.gov) - Jan 11, 2018
P=N/A, N=49, Completed, Sponsor: Zimmer Biomet
Recruiting --> Active, not recruiting Active, not recruiting --> Completed
- ||| dexamethasone sustained-release (TLC599) / Taiwan Liposome Company, Endo
Enrollment closed, Trial primary completion date: Phase IIa, Randomized, Double Blinded, Placebo Controlled, Dose Finding Study for TLC599 in OA Patients (clinicaltrials.gov) - Jan 10, 2018
P2a, N=77, Active, not recruiting, Sponsor: Taiwan Liposome Company
Active, not recruiting --> Completed Recruiting --> Active, not recruiting | Trial primary completion date: Apr 2018 --> Aug 2018
- | Enrollment open, Trial initiation date, Trial primary completion date, Metastases: AMROA: Advanced MR Imaging of Osteoarthritis (clinicaltrials.gov) - Jan 9, 2018
P=N/A, N=15, Recruiting, Sponsor: Cambridge University Hospitals NHS Foundation Trust
Recruiting --> Active, not recruiting | Trial primary completion date: Apr 2018 --> Aug 2018 Not yet recruiting --> Recruiting | Initiation date: Nov 2016 --> Apr 2017 | Trial primary completion date: Mar 2018 --> Dec 2018
- | Trial completion, Trial primary completion date: Periodontal Inflammation and Immunity in Preclinical Rheumatoid Arthritis (clinicaltrials.gov) - Jan 9, 2018
P=N/A, N=146, Completed, Sponsor: University of Colorado, Denver
Not yet recruiting --> Recruiting | Initiation date: Nov 2016 --> Apr 2017 | Trial primary completion date: Mar 2018 --> Dec 2018 Recruiting --> Completed | Trial primary completion date: Jul 2018 --> Dec 2017
- | Trial primary completion date, Adherence: Study Medication Adherence and Its Determinants in Chronic Disease Through the Example of Methotrexate in Chronic Inflammatory Rheumatism (clinicaltrials.gov) - Jan 3, 2018
P=N/A, N=100, Recruiting, Sponsor: Centre Hospitalier Universitaire de N?mes
Recruiting --> Completed | Trial primary completion date: Jul 2018 --> Dec 2017 Trial primary completion date: Mar 2017 --> Mar 2018
- | Trial primary completion date, Discordant: DIAPO: Discrepancies Between Patients and Physicians in Their Perceptions of Rheumatoid Arthritis Disease Activity (clinicaltrials.gov) - Jan 3, 2018
P=N/A, N=200, Recruiting, Sponsor: Centre Hospitalier Universitaire de N?mes
Trial primary completion date: Mar 2017 --> Mar 2018 Trial primary completion date: Feb 2017 --> Mar 2018
- | MIV 710 / Medivir, MIV-711 / Medivir
Trial completion: A Study to Evaluate Safety and Tolerability of MIV-711 in Osteoarthritis Patients (clinicaltrials.gov) - Dec 28, 2017
P2, N=50, Completed, Sponsor: Medivir
Trial primary completion date: Feb 2017 --> Mar 2018 Active, not recruiting --> Completed
- ||| Trial completion: A Trial With Humanized TNF? Monoclonal Antibody Injection by Single Dose and Dose Escalation in Healthy Subjects (clinicaltrials.gov) - Dec 27, 2017
P1, N=72, Completed, Sponsor: Shenyang Sunshine Pharmaceutical Co., LTD.
Active, not recruiting --> Completed Recruiting --> Completed
- | Trial completion, Trial primary completion date: ELECTOR_I: Home Monitoring of Patients With Rheumatoid Arthritis - an eHealth Development Study (clinicaltrials.gov) - Dec 22, 2017
P=N/A, N=240, Completed, Sponsor: Henrik Gudbergsen
Recruiting --> Completed Recruiting --> Completed | Trial primary completion date: Jun 2017 --> Sep 2017
- | Trial completion, Trial primary completion date: PNHA1401: Comparative Assessment of Viscosupplementation With Polynucleotides and Hyaluronic Acid (clinicaltrials.gov) - Dec 21, 2017
P=N/A, N=102, Completed, Sponsor: Istituto Ortopedico Rizzoli
Recruiting --> Completed | Trial primary completion date: Jun 2017 --> Sep 2017 Recruiting --> Completed | Trial primary completion date: Sep 2015 --> Jul 2017
- verinurad (RDEA3170) / AstraZeneca
Phase classification: RDEA3170 and Allopurinol Combination Study in Gout Subjects (clinicaltrials.gov) - Dec 20, 2017
P1b, N=12, Completed, Sponsor: Ardea Biosciences, Inc.
Recruiting --> Completed | Trial primary completion date: Sep 2015 --> Jul 2017 Phase classification: P1 --> P1b
- | ropivacaine / Generic mfg.
Trial completion, Surgery: Effective Pain Management of Interscalene Blocks During Shoulder Surgery (clinicaltrials.gov) - Dec 20, 2017
P=N/A, N=76, Completed, Sponsor: TriHealth Inc.
Phase classification: P1 --> P1b Active, not recruiting --> Completed
- | Enrollment closed, Trial primary completion date: Topical Tripterygium Wilfordii Gel for Moderate Activity Rheumatoid Arthritis (clinicaltrials.gov) - Dec 20, 2017
P=N/A, N=168, Active, not recruiting, Sponsor: Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Active, not recruiting --> Completed Recruiting --> Active, not recruiting | Trial primary completion date: Sep 2018 --> Mar 2018
- ||| New trial: Study of Patient Outcomes 5 Years After Partial Knee Replacement (clinicaltrials.gov) - Dec 19, 2017
P=N/A, N=159, Completed, Sponsor: Athens Orthopedic Clinic, P.A.
- New trial: Study of Surgical Technique With Use of Single-radius Prosthesis in Total Knee Replacement (clinicaltrials.gov) - Dec 19, 2017
P=N/A, N=43, Completed, Sponsor: Athens Orthopedic Clinic, P.A.
- | methylprednisolone acetate / Generic mfg.
New P1 trial: Intra-articular Injections for Knee Osteoarthritis: A Single Blinded Prospective Randomized Trial (clinicaltrials.gov) - Dec 19, 2017
P1, N=0, Withdrawn, Sponsor: Rush University Medical Center
- | methylprednisolone acetate / Generic mfg.
Enrollment change, Trial withdrawal: Intra-articular Injections for Knee Osteoarthritis: A Single Blinded Prospective Randomized Trial (clinicaltrials.gov) - Dec 18, 2017
P1, N=0, Withdrawn, Sponsor: Rush University Medical Center
Recruiting --> Active, not recruiting | Trial primary completion date: Sep 2018 --> Mar 2018 N=150 --> 0 | Not yet recruiting --> Withdrawn | N=150 --> 0 | Not yet recruiting --> Withdrawn | N=150 --> 0 | Not yet recruiting --> Withdrawn | N=150 --> 0 | Not yet recruiting --> Withdrawn
- |||| S-120083 / Shionogi, Purdue
Trial completion: A Study to Evaluate the Analgesic Efficacy and Safety of V120083 in Subjects With Osteoarthritis (OA) of the Knee (clinicaltrials.gov) - Dec 15, 2017
P2a, N=291, Completed, Sponsor: Purdue Pharma LP
N=150 --> 0 | Not yet recruiting --> Withdrawn | N=150 --> 0 | Not yet recruiting --> Withdrawn | N=150 --> 0 | Not yet recruiting --> Withdrawn | N=150 --> 0 | Not yet recruiting --> Withdrawn Active, not recruiting --> Completed
- | Enrollment closed, Enrollment change, Trial primary completion date: Clinical Outcomes With Omni Apex Ultracongruent Knee System (clinicaltrials.gov) - Dec 13, 2017
P=N/A, N=69, Active, not recruiting, Sponsor: Spokane Joint Replacement Center
Active, not recruiting --> Completed Recruiting --> Active, not recruiting | N=56 --> 69 | Trial primary completion date: Nov 2016 --> Nov 2018
- | Enrollment closed, Trial primary completion date: Femoral Remodeling Following Total Hip Arthroplasty With OMNI Apex Modular (clinicaltrials.gov) - Dec 13, 2017
P=N/A, N=73, Active, not recruiting, Sponsor: Spokane Joint Replacement Center
Recruiting --> Active, not recruiting | N=56 --> 69 | Trial primary completion date: Nov 2016 --> Nov 2018 Recruiting --> Active, not recruiting | Trial primary completion date: Nov 2016 --> Nov 2019
- | Enrollment closed, Enrollment change, Trial primary completion date, Surgery: Dual Energy X-ray Absorptiometry (DXA) Comparison Hip Resurfacing Versus Total Hip Arthroplasty (THA) (clinicaltrials.gov) - Dec 13, 2017
P=N/A, N=31, Active, not recruiting, Sponsor: Spokane Joint Replacement Center
Recruiting --> Active, not recruiting | Trial primary completion date: Nov 2016 --> Nov 2019 Recruiting --> Active, not recruiting | N=25 --> 31 | Trial primary completion date: Dec 2016 --> Dec 2018
- | Trial completion, Trial primary completion date: Stryker Triathlon (clinicaltrials.gov) - Dec 13, 2017
P=N/A, N=125, Completed, Sponsor: Spokane Joint Replacement Center
Recruiting --> Active, not recruiting | N=25 --> 31 | Trial primary completion date: Dec 2016 --> Dec 2018 Active, not recruiting --> Completed | Trial primary completion date: Dec 2016 --> Jul 2016
- | Phase classification, Enrollment change, Trial withdrawal, Trial primary completion date: "Blind" vs. Fluoroscopy-Guided Steroid Injections for Knee Osteoarthritis (clinicaltrials.gov) - Dec 12, 2017
P=N/A, N=0, Withdrawn, Sponsor: Johns Hopkins University
Active, not recruiting --> Completed | Trial primary completion date: Dec 2016 --> Jul 2016 Phase classification: P2 --> P=N/A | N=128 --> 0 | Not yet recruiting --> Withdrawn | Trial primary completion date: Apr 2016 --> Jul 2016
- ||||||| Hyrimoz (adalimumab-adaz) / Sandoz
Trial completion: ADMYRA: Clinical Trial to Compare Treatment With GP2017 and Humira (clinicaltrials.gov) - Dec 12, 2017
P3, N=353, Completed, Sponsor: Sandoz
Phase classification: P2 --> P=N/A | N=128 --> 0 | Not yet recruiting --> Withdrawn | Trial primary completion date: Apr 2016 --> Jul 2016 Active, not recruiting --> Completed
- | hyaluronic acid (YYD302) / Yooyoung Pharma
Trial completion: Clinical Trial of YYD302 for Treatment of Osteoarthritis of the Knee (clinicaltrials.gov) - Dec 11, 2017
P1/2, N=30, Completed, Sponsor: Yooyoung Pharmaceutical Co.,Ltd.
Active, not recruiting --> Completed Recruiting --> Completed
- ||| Trial completion: GK10: Cementless Oxford Partial Knee Controlled Observational Study (clinicaltrials.gov) - Dec 8, 2017
P=N/A, N=391, Completed, Sponsor: Zimmer Biomet
Recruiting --> Completed Active, not recruiting --> Completed
- ||| Actemra IV (tocilizumab) / Roche, JW Pharma
Trial completion: Multicenter, Post-marketing, Non-interventional, Observational Study in RA Patients Treated With RoActemra/Actemra (Tocilizumab) (clinicaltrials.gov) - Dec 7, 2017
P=N/A, N=400, Completed, Sponsor: Hoffmann-La Roche
Active, not recruiting --> Completed Recruiting --> Completed
- | Trial completion: Study of X0002 Following Escalating Single and Multiple Doses Administered as Topical Application in Healthy Volunteers (clinicaltrials.gov) - Dec 6, 2017
P1, N=34, Completed, Sponsor: Tianjin XinChen-Techfields Pharma Co., LTD.
Recruiting --> Completed Recruiting --> Completed
- | Trial initiation date: Improvement in Pain and Function Following a Physiotherapy Program in Older Adults With Knee Osteoarthritis (clinicaltrials.gov) - Dec 5, 2017
P=N/A, N=100, Completed, Sponsor: Universidad Rey Juan Carlos
Recruiting --> Completed Initiation date: Sep 2015 --> Feb 2016
- | Enbrel (etanercept) / Pfizer, Amgen
Trial primary completion date: Niclosamide With Etanercept in Rheumatoid Arthritis (clinicaltrials.gov) - Dec 5, 2017
P1/2, N=110, Recruiting, Sponsor: Faiq Gorial
Initiation date: Sep 2015 --> Feb 2016 Trial primary completion date: Apr 2019 --> Apr 2018
- Enrollment change, Trial primary completion date: A Study to Assess Inflammation in Rheumatoid Arthritis Using Molecular Imaging Techniques (clinicaltrials.gov) - Dec 4, 2017
P1, N=10, Terminated, Sponsor: GlaxoSmithKline
Trial primary completion date: Apr 2019 --> Apr 2018 N=13 --> 10 | Trial primary completion date: Jun 2016 --> Oct 2016
- | Trial primary completion date: KUCE: The Knee Usual Care Evaluation Study (clinicaltrials.gov) - Dec 2, 2017
P=N/A, N=906, Terminated, Sponsor: Hospital for Special Surgery, New York
N=13 --> 10 | Trial primary completion date: Jun 2016 --> Oct 2016 Trial primary completion date: Jul 2018 --> Mar 2014
- ||||||| CHS-0214 (etanercept biosimilar) / Coherus Biosci
Trial completion: A Long Term Safety Extension Study (CHS-0214-05) (clinicaltrials.gov) - Dec 2, 2017
P3, N=359, Completed, Sponsor: Coherus Biosciences, Inc.
Trial primary completion date: Jul 2018 --> Mar 2014 Active, not recruiting --> Completed
- |||| Cosentyx (secukinumab) / Novartis
Trial primary completion date: MEASURE4: 16-week Efficacy and 2-year Safety, Tolerability and Efficacy of Secukinumab in Participants With Active Ankylosing Spondylitis (clinicaltrials.gov) - Nov 30, 2017
P3, N=350, Active, not recruiting, Sponsor: Novartis Pharmaceuticals
Active, not recruiting --> Completed Trial primary completion date: Jan 2018 --> Feb 2016
- |||| Plivensia (sirukumab) / J&J
Trial primary completion date: SIRROUND-LTE: Long-term Safety and Efficacy of Sirukumab in Participants With RA Completing Studies CNTO136ARA3002 or CNTO136ARA3003 (clinicaltrials.gov) - Nov 30, 2017
P3, N=1820, Active, not recruiting, Sponsor: Janssen Research & Development, LLC
Trial primary completion date: Jan 2018 --> Feb 2016 Trial primary completion date: Nov 2019 --> Apr 2018
- | Enbrel (etanercept) / Pfizer, Amgen
Trial initiation date: Niclosamide With Etanercept in Rheumatoid Arthritis (clinicaltrials.gov) - Nov 30, 2017
P1/2, N=110, Recruiting, Sponsor: Faiq Gorial
Trial primary completion date: Nov 2019 --> Apr 2018 Initiation date: Apr 2017 --> Aug 2017
- |||| evobrutinib (M2951) / EMD Serono
Trial completion: MS200527-0081: Safety and Efficacy Study of M2951 in Participants With Rheumatoid Arthritis (clinicaltrials.gov) - Nov 29, 2017
P2a, N=65, Completed, Sponsor: EMD Serono Research & Development Institute, Inc.
Initiation date: Apr 2017 --> Aug 2017 Active, not recruiting --> Completed
- | prezalumab (AMG 557) / Amgen, AstraZeneca
Enrollment closed, Enrollment change: A Phase 2a, Randomized, Placebo Controlled, Study to Evaluate the Safety and Efficacy of AMG 557/MEDI5872 in Primary Sj (clinicaltrials.gov) - Nov 27, 2017
P2a, N=32, Active, not recruiting, Sponsor: MedImmune LLC
Active, not recruiting --> Completed Recruiting --> Active, not recruiting | N=42 --> 32
- | remifentanil / Generic mfg., duloxetine / Generic mfg.
Trial completion, Trial primary completion date: IPRO: Imaging Pain Relief in Osteoarthritis (clinicaltrials.gov) - Nov 27, 2017
P4, N=77, Completed, Sponsor: University of Nottingham
Recruiting --> Active, not recruiting | N=42 --> 32 Active, not recruiting --> Completed | Trial primary completion date: Sep 2017 --> Jun 2016
- | Trial completion, Enrollment change: Reconstruction of Complex Proximal Humeral Fractures. (clinicaltrials.gov) - Nov 27, 2017
P=N/A, N=20, Completed, Sponsor: Balgrist University Hospital
Active, not recruiting --> Completed | Trial primary completion date: Sep 2017 --> Jun 2016 Recruiting --> Completed | N=80 --> 20
- || Trial primary completion date: VEGA Prospective Kiel (clinicaltrials.gov) - Nov 27, 2017
P=N/A, N=100, Recruiting, Sponsor: Aesculap AG
Recruiting --> Completed | N=80 --> 20 Trial primary completion date: Sep 2017 --> Apr 2018