Anemia, Sickle Cell MOAs

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Anemia, Sickle Cell

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Phase N/A 1 2 3 4 Products	0	1	2	3	4	5	6	7	8	9	10



CD20 inhib




µ-opioid agon




Alkylating agent




CD20 inhib




HDAC2 inhib




Calcineurin inhib




Complement C5 inhib




HMG-CoA reductase inhib




IMPDH inhib




Immunosuppressant




NMDAR antag




PDGFR inhib




Stem cell stim




5-lipoxygenase activating protein inhib




5-lipoxygenase inhib




Adenosine A2A receptor agon




Adenosine A2A receptor agon




Amyloid β protein inhib




Angiogenesis inhib




Apoptosis inducer




Apoptosis stim




Bone morphogenetic protein receptor type II mod




Bone resorption factor inhib




CD20 inhib




Cytokine mod




DGAT inhib




Endothelin A receptor antag




Endothelin B receptor antag




Erythropoiesis stimulating agent




Erythropoiesis-fetal Hb stim




Factor X inhib




Fatty acid inhib




GCR agon




Histamine release inhib




IL-10 stim




IL-10 stim




IL-1β inhib




IL-6 inhib




LMWH inhib




Nitric oxide synthase stim




Osteoclast inhib




PAH stim




PDE5 inhib




PDGFR inhib




Phospholipase A2 inhib




T-cell activation inhib




TNFα inhib




VEGF-A inhib




c-KIT inhib




cGMP agon



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