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33 Companies |
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35 Products |
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35 Products |
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38 Mechanisms of Action |
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1 Trial |
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827 News |
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- Enrollment open: OTS ETOH-3: Oxytocin Treatment of Alcohol Dependence (clinicaltrials.gov) - May 28, 2016
P2, N=50, Recruiting, Sponsor: University of North Carolina, Chapel Hill
Not yet recruiting --> Recruiting
- New P1 trial: AEDED: Interaction of Alcohol With Energy Drinks (clinicaltrials.gov) - May 13, 2016
P1, N=16, Not yet recruiting, Sponsor: Parc de Salut Mar
- Enrollment closed, Enrollment change, Trial primary completion date: Tailored Mobile Text Messaging to Reduce Problem Drinking (clinicaltrials.gov) - May 13, 2016
P=N/A, N=174, Active, not recruiting, Sponsor: Northwell Health
Not yet recruiting --> Recruiting Recruiting --> Active, not recruiting | N=300 --> 174 | Trial primary completion date: Jul 2015 --> Dec 2015
- Trial primary completion date: Project Relay Model for Recruiting Alcohol Dependent Patients in General Hospitals (clinicaltrials.gov) - May 12, 2016
P=N/A, N=1000, Recruiting, Sponsor: University of Southern Denmark
Recruiting --> Active, not recruiting | N=300 --> 174 | Trial primary completion date: Jul 2015 --> Dec 2015 Trial primary completion date: Feb 2016 --> Jun 2017
- Campral EC (acamprosate delayed release) / EMD Serono, Nippon Shinyaku
Trial termination: Study of Acamprosate to Prevent Alcohol Relapse in Criminal Justice Supervisees (clinicaltrials.gov) - May 12, 2016
P4, N=26, Terminated, Sponsor: Virginia Commonwealth University
Trial primary completion date: Feb 2016 --> Jun 2017 Completed --> Terminated; Not enough sugjects enrolled before funding ran out
- naltrexone / Generic mfg.
Trial completion: Genetic and Brain Mechanisms of Naltrexone's Treatment Efficacy for Alcoholism (clinicaltrials.gov) - May 5, 2016
P4, N=152, Completed, Sponsor: Medical University of South Carolina
Completed --> Terminated; Not enough sugjects enrolled before funding ran out Active, not recruiting --> Completed
- Trial primary completion date: Effect of Anti-craving Medication on Cognitive Functions in Alcohol Dependence: an ERP Study (clinicaltrials.gov) - May 4, 2016
P=N/A, N=80, Recruiting, Sponsor: Brugmann University Hospital
Active, not recruiting --> Completed Trial primary completion date: Dec 2016 --> Jun 2017
- Selincro (nalmefene oral) / Lundbeck, Acorda
Enrollment closed, Trial primary completion date: A Single-center, Open-label, Single-dose Study Investigating the Safety, Tolerability, and Pharmacokinetic Properties of Nalmefene 10 mg Tablets in Healthy Japanese Male Subjects (clinicaltrials.gov) - Apr 26, 2016
P1, N=7, Active, not recruiting, Sponsor: Otsuka Pharmaceutical Co., Ltd.
Trial primary completion date: Dec 2016 --> Jun 2017 Recruiting --> Active, not recruiting | Trial primary completion date: Mar 2016 --> Aug 2016
- Trial completion, Enrollment change: Comorbidities and Virologic Outcome Among Patients on Anti-retroviral Therapy in Rural Lesotho (clinicaltrials.gov) - Apr 21, 2016
P=N/A, N=1754, Completed, Sponsor: Swiss Tropical & Public Health Institute
Recruiting --> Active, not recruiting | Trial primary completion date: Mar 2016 --> Aug 2016 Active, not recruiting --> Completed | N=1000 --> 1754
- Enrollment closed, Trial primary completion date: Integrated Collaborative Care for Substance Use Disorders (clinicaltrials.gov) - Apr 20, 2016
P=N/A, N=397, Active, not recruiting, Sponsor: RAND
Active, not recruiting --> Completed | N=1000 --> 1754 Recruiting --> Active, not recruiting | Trial primary completion date: Apr 2017 --> Jul 2016
- Arcalyst (rilonacept) / Regeneron, Kiniksa
Trial completion, Enrollment change, Trial primary completion date: A Safety and Efficacy Study of Mycophenolate Mofetil and Rilonacept in Patients With Alcoholic Hepatitis (clinicaltrials.gov) - Apr 20, 2016
P2, N=5, Completed, Sponsor: Timothy Morgan, MD
Recruiting --> Active, not recruiting | Trial primary completion date: Apr 2017 --> Jul 2016 Not yet recruiting --> Completed | N=186 --> 5 | Trial primary completion date: Sep 2018 --> Apr 2016
- Phase classification: Oxytocin in Alcohol Use Disorder (clinicaltrials.gov) - Apr 15, 2016
P1, N=32, Not yet recruiting, Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Not yet recruiting --> Completed | N=186 --> 5 | Trial primary completion date: Sep 2018 --> Apr 2016 Phase classification: P=N/A --> P1
- Trial primary completion date: Project Health Link: Connecting Patients With Services (clinicaltrials.gov) - Apr 14, 2016
P=N/A, N=686, Completed, Sponsor: University of Michigan
Phase classification: P=N/A --> P1 Trial primary completion date: Jul 2009 --> Dec 2009
- diazepam / Generic mfg.
Trial primary completion date: DIAMA: Impact of a One-month Long Detoxification Diazepam Treatment on Early Alcohol Relapse (clinicaltrials.gov) - Apr 9, 2016
P=N/A, N=164, Recruiting, Sponsor: University Hospital, Lille
Trial primary completion date: Jul 2009 --> Dec 2009 Trial primary completion date: Jul 2018 --> Jul 2017
- Trial completion: Project Health Link: Connecting Patients With Services (clinicaltrials.gov) - Apr 9, 2016
P=N/A, N=686, Completed, Sponsor: University of Michigan
Trial primary completion date: Jul 2018 --> Jul 2017 Not yet recruiting --> Completed
- Enrollment closed, Enrollment change, Trial primary completion date: SBIRT Implementation for Adolescents in Urban Federally Qualified Health Centers (clinicaltrials.gov) - Apr 8, 2016
P=N/A, N=98, Active, not recruiting, Sponsor: Friends Research Institute, Inc.
Not yet recruiting --> Completed Recruiting --> Active, not recruiting | N=2168 --> 98 | Trial primary completion date: Mar 2016 --> Jun 2016
- ondansetron / Generic mfg.
Trial completion, Enrollment change: ARCH Research Protocol for Provider Alcohol Pharmacotherapy Training and Assessment (clinicaltrials.gov) - Apr 8, 2016
P=N/A, N=236, Completed, Sponsor: University of Alabama at Birmingham
Recruiting --> Active, not recruiting | N=2168 --> 98 | Trial primary completion date: Mar 2016 --> Jun 2016 Recruiting --> Completed | N=450 --> 236
- quetiapine / Generic mfg.
Enrollment change: Quetiapine for Bipolar Disorder and Alcohol Dependence (clinicaltrials.gov) - Apr 8, 2016
P4, N=90, Completed, Sponsor: University of Texas Southwestern Medical Center
Recruiting --> Completed | N=450 --> 236 N=120 --> 90
- Trial completion: Health Explorer - Optimizing Alcohol Brief Interventions (clinicaltrials.gov) - Apr 8, 2016
P=N/A, N=750, Completed, Sponsor: University of Michigan
N=120 --> 90 Active, not recruiting --> Completed
- Enrollment closed, Enrollment change, Trial primary completion date: PC: Web Intervention for Concerned Partners to Prevent Service Member Alcohol Abuse Abuse (clinicaltrials.gov) - Apr 7, 2016
P=N/A, N=312, Active, not recruiting, Sponsor: RAND
Active, not recruiting --> Completed Recruiting --> Active, not recruiting | N=100 --> 312 | Trial primary completion date: May 2016 --> Oct 2015
- | Selincro (nalmefene oral) / Lundbeck, Acorda
Trial termination: Study of 18 mg Selincro® As-needed Use, in the Treatment of Patients With Alcohol Dependence in Primary Care (clinicaltrials.gov) - Mar 30, 2016
P4, N=378, Terminated, Sponsor: H. Lundbeck A/S
Recruiting --> Active, not recruiting | N=100 --> 312 | Trial primary completion date: May 2016 --> Oct 2015 Completed --> Terminated; The study was terminated due to enrolment challenges
- New trial: Accuracy of Self-estimation of Blood Alcohol Concentration Compared to Object Values (clinicaltrials.gov) - Mar 30, 2016
P=N/A, N=55, Completed, Sponsor: St. Luke's Hospital and Health Network, Pennsylvania
- baclofen / Generic mfg.
Enrollment change, Trial termination, Trial primary completion date: Preventing Alcohol Withdrawal With Oral Baclofen (clinicaltrials.gov) - Mar 24, 2016
P2, N=17, Terminated, Sponsor: Essentia Health
Completed --> Terminated; The study was terminated due to enrolment challenges N=212 --> 17 | Recruiting --> Terminated | Trial primary completion date: Apr 2016 --> Jun 2015; The enrollment in the study was too limited for meaningful data analysis.
- Enrollment closed: Eye Movement Desensitization and Reprocessing (EMDR) in Alcohol Dependent Patients (clinicaltrials.gov) - Mar 21, 2016
P=N/A, N=109, Active, not recruiting, Sponsor: IrisZorg
N=212 --> 17 | Recruiting --> Terminated | Trial primary completion date: Apr 2016 --> Jun 2015; The enrollment in the study was too limited for meaningful data analysis. Recruiting --> Active, not recruiting
- Trial completion, Enrollment change, Trial primary completion date: Modification of Cognitive Processing Therapy (CPT-C) for PTSD and Alcohol Dependence (clinicaltrials.gov) - Mar 21, 2016
P2/3, N=9, Completed, Sponsor: Yale University
Recruiting --> Active, not recruiting Recruiting --> Completed | N=20 --> 9 | Trial primary completion date: Oct 2016 --> Oct 2014
- Enrollment change: Cognitive Processing Intervention for Trauma, HIV/STI Risks, and Substance Use Among Native Women (clinicaltrials.gov) - Mar 19, 2016
P=N/A, N=100, Recruiting, Sponsor: University of Washington
Recruiting --> Completed | N=20 --> 9 | Trial primary completion date: Oct 2016 --> Oct 2014 N=56 --> 100
- |||| Trial completion, Trial primary completion date: REVIVE(Randomized Exploratory Clinical Trial to Evaluate the Safety and Effectiveness of Stem Cell Product in Alcoholic Liver Cirrhosis Patient) (clinicaltrials.gov) - Mar 19, 2016
P2, N=72, Completed, Sponsor: Pharmicell Co., Ltd.
N=56 --> 100 Recruiting --> Completed | Trial primary completion date: Sep 2015 --> Mar 2016
- | aripiprazole / Generic mfg.
Trial completion: Aripiprazole Effects on Alcohol Drinking and Craving (clinicaltrials.gov) - Mar 19, 2016
P3, N=99, Completed, Sponsor: Medical University of South Carolina
Recruiting --> Completed | Trial primary completion date: Sep 2015 --> Mar 2016 Recruiting --> Completed
- Trial completion: Manipulation of Breath Alcohol Tests: Can Specific Techniques Alter Blood Alcohol Concentration Readings? (clinicaltrials.gov) - Mar 18, 2016
P=N/A, N=54, Completed, Sponsor: St. Luke's Hospital and Health Network, Pennsylvania
Recruiting --> Completed Recruiting --> Completed
- New P1 trial: Oxytocin in Alcohol Use Disorder (clinicaltrials.gov) - Mar 18, 2016
P=N/A, N=32, Not yet recruiting, Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA)
- Trial completion: Cognitive Retraining and Brain Stimulation for Alcohol Use (clinicaltrials.gov) - Mar 17, 2016
P=N/A, N=93, Completed, Sponsor: The Mind Research Network
Recruiting --> Completed Recruiting --> Completed
- Enrollment change, Trial termination, Head-to-Head: FoBeMA: Internet-Based Relapse Prevention vs Face to Face Therapy at an Employee Assistance Program (clinicaltrials.gov) - Mar 15, 2016
P=N/A, N=1, Terminated, Sponsor: Karolinska Institutet
N=90 --> 1 | Recruiting --> Terminated; Only 1 participant recruited to study. Qs addressed in other ongoing studies.
- Enrollment closed, Trial primary completion date: Supportive Text Messages to Reduce Mood Symptoms and Problem Drinking- Randomised Controlled Pilot Trials (clinicaltrials.gov) - Mar 15, 2016
P=N/A, N=131, Active, not recruiting, Sponsor: University of Alberta
Qs addressed in other ongoing studies. Recruiting --> Active, not recruiting | Trial primary completion date: Dec 2016 --> Aug 2016
- prazosin / Generic mfg.
Enrollment change, Trial termination: Prazosin for ETOH or Cocaine Craving (clinicaltrials.gov) - Mar 15, 2016
P=N/A, N=8, Terminated, Sponsor: VA Office of Research and Development
Recruiting --> Active, not recruiting | Trial primary completion date: Dec 2016 --> Aug 2016 N=32 --> 8 | Completed --> Terminated; Experimental procedure did not induce sufficient craving to determine any possible effect of medication.
- Trial primary completion date: SF-FASD: Parenting Training for Children With FASD (clinicaltrials.gov) - Mar 10, 2016
P=N/A, N=200, Recruiting, Sponsor: IWK Health Centre
N=32 --> 8 | Completed --> Terminated; Experimental procedure did not induce sufficient craving to determine any possible effect of medication. Trial primary completion date: Jan 2016 --> Jul 2016
- Trial completion: Usability Study for SOBERLINK System (clinicaltrials.gov) - Mar 10, 2016
P=N/A, N=40, Completed, Sponsor: Soberlink Healthcare LLC
Trial primary completion date: Jan 2016 --> Jul 2016 Recruiting --> Completed
- Vivitrol (naltrexone extended-release injectable suspension) / Alkermes
Trial completion, Enrollment change, Trial primary completion date: INSPIRE: Alcohol Pharmacotherapy for HIV+ Prisoners (clinicaltrials.gov) - Mar 8, 2016
P=N/A, N=100, Completed, Sponsor: Yale University
Recruiting --> Completed Active, not recruiting --> Completed | N=125 --> 100 | Trial primary completion date: Aug 2016 --> Aug 2015
- Selincro (nalmefene oral) / Lundbeck, Acorda
Enrollment open: USE-PACT: Use of Selincro and Impact on Usual Practice (clinicaltrials.gov) - Mar 8, 2016
P=N/A, N=1000, Recruiting, Sponsor: University of Bordeaux
Active, not recruiting --> Completed | N=125 --> 100 | Trial primary completion date: Aug 2016 --> Aug 2015 Not yet recruiting --> Recruiting
- midazolam hydrochloride / Generic mfg.
Enrollment change, Trial withdrawal, Trial primary completion date: Pilot Study Evaluating Stress Response and Immune Function in Mechanically Ventilated Patients With Alcohol Use Disorders Treated With Propofol or Midazolam (clinicaltrials.gov) - Mar 1, 2016
P4, N=0, Withdrawn, Sponsor: Virginia Commonwealth University
Not yet recruiting --> Recruiting N=10 --> 0 | Suspended --> Withdrawn | Trial primary completion date: Jul 2012 --> Mar 2009
- | Enrollment change: Brief Therapy Intervention for Heavy/Hazardous Drinking in HIV-Positive Women (clinicaltrials.gov) - Feb 27, 2016
P3, N=387, Completed, Sponsor: Johns Hopkins University
N=10 --> 0 | Suspended --> Withdrawn | Trial primary completion date: Jul 2012 --> Mar 2009 N=300 --> 387
- Enrollment change: Helping Families Help Veterans With PTSD and Alcohol Abuse: An RCT of VA-CRAFT (clinicaltrials.gov) - Feb 25, 2016
P=N/A, N=66, Active, not recruiting, Sponsor: VA Office of Research and Development
N=300 --> 387 N=336 --> 66
- Trial completion: Preventing FAS/ARND in Russian Children (clinicaltrials.gov) - Feb 21, 2016
P=N/A, N=767, Completed, Sponsor: University of Oklahoma
N=336 --> 66 Active, not recruiting --> Completed
- Trial primary completion date, Head-to-Head: EFAR-Spain: Primary Care-based Facilitated Access to a Web Based Brief Intervention to Reduce Alcohol Consumption (clinicaltrials.gov) - Feb 21, 2016
P=N/A, N=1000, Recruiting, Sponsor: Hospital Clinic of Barcelona
Active, not recruiting --> Completed Trial primary completion date: Jan 2016 --> Jan 2017
- topiramate / Generic mfg.
Enrollment change, Trial termination, Trial primary completion date: Topiramate to Reduce Heavy Drinking in HIV-Positive Heavy Drinkers (clinicaltrials.gov) - Feb 18, 2016
P2, N=4, Terminated, Sponsor: University of Pennsylvania
Trial primary completion date: Jan 2016 --> Jan 2017 N=60 --> 4 | Active, not recruiting --> Terminated | Trial primary completion date: Jun 2014 --> Jan 2014; We terminated the study due to problems recruiting alcoholic subjects with HIV.
- |||| Selincro (nalmefene oral) / Lundbeck, Acorda
Trial completion, Enrollment change: Study of 18 mg Selincro® As-needed Use, in the Treatment of Patients With Alcohol Dependence in Primary Care (clinicaltrials.gov) - Feb 18, 2016
P4, N=378, Completed, Sponsor: H. Lundbeck A/S
N=60 --> 4 | Active, not recruiting --> Terminated | Trial primary completion date: Jun 2014 --> Jan 2014; We terminated the study due to problems recruiting alcoholic subjects with HIV. Active, not recruiting --> Completed | N=635 --> 378
- Trial primary completion date: Effect of Anti-craving Medication on Cognitive Functions in Alcohol Dependence: an ERP Study (clinicaltrials.gov) - Feb 12, 2016
P=N/A, N=80, Recruiting, Sponsor: Brugmann University Hospital
Active, not recruiting --> Completed | N=635 --> 378 Trial primary completion date: Dec 2015 --> Dec 2016
- Trial completion, Enrollment change, Trial primary completion date: Long Term Effect of Aggressive Nutritional Management on Survival in Patients With Alcoholic Liver Disease (clinicaltrials.gov) - Feb 11, 2016
P=N/A, N=147, Completed, Sponsor: Institute of Liver and Biliary Sciences, India
Trial primary completion date: Dec 2015 --> Dec 2016 Recruiting --> Completed | N=856 --> 147 | Trial primary completion date: May 2016 --> Dec 2015
- Selincro (nalmefene oral) / Lundbeck, Acorda
New P1 trial: A Single-center, Open-label, Single-dose Study Investigating the Safety, Tolerability, and Pharmacokinetic Properties of Nalmefene 10 mg Tablets in Healthy Japanese Male Subjects (clinicaltrials.gov) - Feb 10, 2016
P1, N=7, Recruiting, Sponsor: Otsuka Pharmaceutical Co., Ltd.
- lorazepam / Generic mfg., dexmedetomidine / Generic mfg.
Clinical: Dexmedetomidine (Precedex®) for Severe Alcohol Withdrawal Syndrome (AWS) and Alcohol Withdrawal Delirium (AWD) (clinicaltrials.gov) - Feb 10, 2016
P4, N=49, Terminated, Sponsor: Denver Health and Hospital Authority
Recruiting --> Completed | N=856 --> 147 | Trial primary completion date: May 2016 --> Dec 2015 N=150 --> 49 | Recruiting --> Terminated; DSMB recommendation for slow enrollment
- Enrollment change, Trial withdrawal: Trial of Computerized MET for Adolescent Substance Use (clinicaltrials.gov) - Feb 9, 2016
P1, N=0, Withdrawn, Sponsor: Children's Hospital Boston
N=150 --> 49 | Recruiting --> Terminated; DSMB recommendation for slow enrollment N=375 --> 0 | Not yet recruiting --> Withdrawn