AL Amyloidosis MOAs - LARVOL Sigma

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Phase N/A 1 2 3 4 Products	0	2	4	6	8	10	12	14	16	18	20



Purinergic receptor P1 agon




T-cell activation inhib




µ-opioid agon




DNA replication inhib




TNFα inhib




IL-6 inhib




Proteasome inhib




CD122 agon




Calcineurin inhib




IFNα 2b stim




IL-10 stim




IL-1β inhib




IL-6 inhib




IMPDH inhib




Immunosuppressant




NMDAR antag




PDGFR inhib




PDGFR inhib




c-KIT inhib




5-lipoxygenase activating protein inhib




Apoptosis stim




Bone morphogenetic protein receptor type II mod




Cytokine mod




DGAT-1 inhib




DNMT inhib




Factor X inhib




GCR agon




GM-CSF agon




GM-CSF agon




Histamine release inhib




IL-12 inhib




IL-2 stim




Integrin inhib




Kappa receptor agon




LMWH inhib




Microtubule stabilizer




Na+ channel antag




Platelet aggregation inhib




T-cell activation inhib




VEGFR inhib




mTOR inhib




mTOR inhib



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