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13 Companies |
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11 Products |
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11 Products |
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13 Mechanisms of Action |
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1 Trial |
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94 News |
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- | Solu-Cortef (hydrocortisone sodium succinate injection) / Pfizer, NN1213 / Novo Nordisk
Trial termination: Continuous Subcutaneous Hydrocortisone Infusion In Addison's Disease and Type 1 Diabetes (clinicaltrials.gov) - Mar 2, 2024
P2, N=4, Terminated, Sponsor: Haukeland University Hospital
Completed --> Terminated; recruitment difficulties
- | Trial completion, Trial completion date, Trial primary completion date: Cortisol Response to Low Dose Cosyntropin Stimulation Test in the Late Afternoon (clinicaltrials.gov) - Jan 18, 2019
P=N/A, N=20, Completed, Sponsor: Bnai Zion Medical Center
Completed --> Terminated; recruitment difficulties Active, not recruiting --> Completed | Trial completion date: Jan 2018 --> Aug 2018 | Trial primary completion date: Aug 2017 --> Aug 2018
- | Trial completion, Surgery: Impact of Pre-operative Steroids on Adrenal Insufficiency (clinicaltrials.gov) - Jan 15, 2019
P=N/A, N=50, Completed, Sponsor: University of Alabama at Birmingham
Active, not recruiting --> Completed | Trial completion date: Jan 2018 --> Aug 2018 | Trial primary completion date: Aug 2017 --> Aug 2018 Active, not recruiting --> Completed
- | Enrollment closed, Surgery: Impact of Pre-operative Steroids on Adrenal Insufficiency (clinicaltrials.gov) - Dec 24, 2018
P=N/A, N=50, Active, not recruiting, Sponsor: University of Alabama at Birmingham
Active, not recruiting --> Completed Recruiting --> Active, not recruiting
- | Trial completion date, Trial primary completion date, Surgery: Impact of Pre-operative Steroids on Adrenal Insufficiency (clinicaltrials.gov) - Jul 18, 2018
P=N/A, N=40, Recruiting, Sponsor: University of Alabama at Birmingham
Recruiting --> Active, not recruiting Trial completion date: Jun 2018 --> Mar 2019 | Trial primary completion date: Apr 2018 --> Dec 2018
- | NN1213 / Novo Nordisk
Trial completion, Trial completion date, Trial primary completion date: Newborn Screening for Adrenoleukodystrophy (clinicaltrials.gov) - Jul 12, 2018
P=N/A, N=45796, Completed, Sponsor: National Taiwan University Hospital
Trial completion date: Jun 2018 --> Mar 2019 | Trial primary completion date: Apr 2018 --> Dec 2018 Recruiting --> Completed | Trial completion date: Jun 2018 --> Aug 2017 | Trial primary completion date: Nov 2017 --> Aug 2017
- | NN1213 / Novo Nordisk
Enrollment change, Trial withdrawal: Early Diagnosis Of Childhood Cerebral ALD (clinicaltrials.gov) - Jul 6, 2018
P=N/A, N=0, Withdrawn, Sponsor: Masonic Cancer Center, University of Minnesota
Recruiting --> Completed | Trial completion date: Jun 2018 --> Aug 2017 | Trial primary completion date: Nov 2017 --> Aug 2017 N=100 --> 0 | Not yet recruiting --> Withdrawn
- | Trial completion: Allogeneic Bone Marrow Transplant for Inherited Metabolic Disorders (clinicaltrials.gov) - Feb 5, 2018
P2, N=46, Completed, Sponsor: Masonic Cancer Center, University of Minnesota
N=100 --> 0 | Not yet recruiting --> Withdrawn Active, not recruiting --> Completed
- | Metopirone (metyrapone) / Perrigo Company
Trial completion, Trial primary completion date: Diagnosis of Central Adrenal Insufficiency in Patients With Prader-Willi Syndrome (clinicaltrials.gov) - Jan 29, 2018
P=N/A, N=23, Completed, Sponsor: Nationwide Children's Hospital
Active, not recruiting --> Completed Recruiting --> Completed | Trial primary completion date: Dec 2015 --> Aug 2016
- | Trial completion, Trial primary completion date: National Education Programme for Patients With Chronic Adrenal Insufficiency (clinicaltrials.gov) - Jan 23, 2018
P=N/A, N=528, Completed, Sponsor: Wuerzburg University Hospital
Recruiting --> Completed | Trial primary completion date: Dec 2015 --> Aug 2016 Recruiting --> Completed | Trial primary completion date: Dec 2016 --> Nov 2017
- | Trial initiation date, Trial primary completion date, IO biomarker: Early Diagnosis Of Childhood Cerebral ALD (clinicaltrials.gov) - Dec 5, 2017
P=N/A, N=100, Not yet recruiting, Sponsor: Masonic Cancer Center, University of Minnesota
Recruiting --> Completed | Trial primary completion date: Dec 2016 --> Nov 2017 Initiation date: Nov 2017 --> Nov 2018 | Trial primary completion date: Jul 2022 --> Jul 2023
- | Trial primary completion date, Surgery: Impact of Pre-operative Steroids on Adrenal Insufficiency (clinicaltrials.gov) - Nov 17, 2017
P=N/A, N=40, Recruiting, Sponsor: University of Alabama at Birmingham
Initiation date: Nov 2017 --> Nov 2018 | Trial primary completion date: Jul 2022 --> Jul 2023 Trial primary completion date: Dec 2017 --> Apr 2018
- | dexamethasone / Generic mfg.
Trial completion: Bioavailability of Infacort When Administered Onto Food Compared to Direct Oral Administration (clinicaltrials.gov) - Nov 9, 2017
P1, N=19, Completed, Sponsor: Diurnal Limited
Trial primary completion date: Dec 2017 --> Apr 2018 Recruiting --> Completed
- | Trial initiation date, IO biomarker: Early Diagnosis Of Childhood Cerebral ALD (clinicaltrials.gov) - Oct 25, 2017
P=N/A, N=100, Not yet recruiting, Sponsor: Masonic Cancer Center, University of Minnesota
Recruiting --> Completed Initiation date: Aug 2017 --> Nov 2017
- ||||||| Qizenday (biotin) / MedDay
Trial completion: MD1003-AMN MD1003 in Adrenomyeloneuropathy (clinicaltrials.gov) - Oct 9, 2017
P2/3, N=67, Completed, Sponsor: MedDay Pharmaceuticals SA
Initiation date: Aug 2017 --> Nov 2017 Active, not recruiting --> Completed
- | Enrollment closed, Trial primary completion date: Cortisol Response to Low Dose Cosyntropin Stimulation Test in the Late Afternoon (clinicaltrials.gov) - Aug 22, 2017
P=N/A, N=20, Active, not recruiting, Sponsor: Bnai Zion Medical Center
Active, not recruiting --> Completed Not yet recruiting --> Active, not recruiting | Trial primary completion date: Apr 2018 --> Aug 2017
- | hydrocortisone / Generic mfg.
Trial completion, Enrollment change, Trial primary completion date, IO biomarker: Dual RElease Hydrocortisone Versus conventionAl Glucocorticoid replaceMent Therapy in Hypocortisolism (DREAM) (clinicaltrials.gov) - Jun 27, 2017
P4, N=89, Completed, Sponsor: University of Roma La Sapienza
Not yet recruiting --> Active, not recruiting | Trial primary completion date: Apr 2018 --> Aug 2017 Recruiting --> Completed | N=50 --> 89 | Trial primary completion date: Sep 2015 --> Jun 2016
- | dexamethasone / Generic mfg.
New P1 trial: Bioavailability of Infacort When Administered Onto Food Compared to Direct Oral Administration (clinicaltrials.gov) - Jun 5, 2017
P1, N=18, Recruiting, Sponsor: Diurnal Limited
- | prednisone / Generic mfg.
Trial completion, Trial initiation date, Trial primary completion date: Vapreda: Vaginal Prednisone Administration for Prevention of Adrenal Crisis (clinicaltrials.gov) - May 30, 2017
P2, N=12, Completed, Sponsor: Wuerzburg University Hospital
Recruiting --> Completed | N=50 --> 89 | Trial primary completion date: Sep 2015 --> Jun 2016 Not yet recruiting --> Completed | Initiation date: Apr 2016 --> Jan 2017 | Trial primary completion date: Oct 2016 --> Apr 2017
- | New trial: Cortisol Response to Low Dose Cosyntropin Stimulation Test in the Late Afternoon (clinicaltrials.gov) - Mar 8, 2017
P=N/A, N=20, Not yet recruiting, Sponsor: Bnai Zion Medical Center
- | Efmody (hydrocortisone modified release) / Neurocrine
New P1 trial: A Two-part, Study to Compare the Pharmacokinetics and Dose Proportionality of up to 6 Chronocort Formulations (clinicaltrials.gov) - Feb 14, 2017
P1, N=28, Completed, Sponsor: Diurnal Limited
- NN1213 / Novo Nordisk
Trial completion: Ovarian Follicle Function in Patients With Primary Ovarian Failure (clinicaltrials.gov) - Feb 12, 2017
P=N/A, N=1134, Completed, Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Not yet recruiting --> Completed | Initiation date: Apr 2016 --> Jan 2017 | Trial primary completion date: Oct 2016 --> Apr 2017 Active, not recruiting --> Completed
- | Efmody (hydrocortisone modified release) / Neurocrine
New P1 trial: An Open Label Study in Healthy Volunteers to Compare Chronocort (clinicaltrials.gov) - Jan 12, 2017
P1, N=30, Completed, Sponsor: Diurnal Limited
- Enrollment open: Newborn Screening for Adrenoleukodystrophy (clinicaltrials.gov) - Jan 6, 2017
P=N/A, N=60000, Recruiting, Sponsor: National Taiwan University Hospital
Active, not recruiting --> Completed Not yet recruiting --> Recruiting
- Solu-Cortef (hydrocortisone sodium succinate injection) / Pfizer
Trial completion, Enrollment change: Continuous Subcutaneous Hydrocortisone Infusion In Addison's Disease and Type 1 Diabetes (clinicaltrials.gov) - Dec 30, 2016
P2, N=2, Completed, Sponsor: Haukeland University Hospital
Not yet recruiting --> Recruiting Active, not recruiting --> Completed | N=10 --> 2
- Trial completion, Trial initiation date: Adrenal Function After Living Kidney Donation (clinicaltrials.gov) - Dec 29, 2016
P=N/A, N=30, Completed, Sponsor: University of Zurich
Active, not recruiting --> Completed | N=10 --> 2 Recruiting --> Completed | Initiation date: Dec 2005 --> Jan 2007
- Solu-Cortef (hydrocortisone sodium succinate injection) / Pfizer
Trial completion, Trial primary completion date: Comparison of Cortisol Pump With Standard Treatment for Congenital Adrenal Hyperplasia (clinicaltrials.gov) - Dec 6, 2016
P2, N=8, Completed, Sponsor: National Institutes of Health Clinical Center (CC)
Recruiting --> Completed | Initiation date: Dec 2005 --> Jan 2007 Active, not recruiting --> Completed | Trial primary completion date: Jun 2017 --> Dec 2016
- || Qizenday (biotin) / MedDay
New P2/3 trial: MD1003-AMN MD1003 in Adrenomyeloneuropathy (clinicaltrials.gov) - Nov 13, 2016
P2/3, N=67, Active, not recruiting, Sponsor: MedDay Pharmaceuticals SA
- New trial, Surgery: Impact of Pre-operative Steroids on Adrenal Insufficiency (clinicaltrials.gov) - Nov 7, 2016
P=N/A, N=40, Recruiting, Sponsor: University of Alabama at Birmingham
- New trial: Newborn Screening for Adrenoleukodystrophy (clinicaltrials.gov) - Nov 2, 2016
P=N/A, N=60000, Not yet recruiting, Sponsor: National Taiwan University Hospital
- New trial, IO biomarker: Early Diagnosis Of Childhood Cerebral ALD (clinicaltrials.gov) - Oct 27, 2016
P=N/A, N=100, Not yet recruiting, Sponsor: Masonic Cancer Center, University of Minnesota
- acetylcysteine solution / Generic mfg.
Biomarker, Enrollment change: A Clinical Trial for AMN: Validation of Biomarkers of Oxidative Stress, Efficacy and Safety of a Mixture of Antioxidants (clinicaltrials.gov) - Sep 19, 2016
P2, N=13, Completed, Sponsor: Onofre, Aurora Pujol, M.D.
Active, not recruiting --> Completed | Trial primary completion date: Jun 2017 --> Dec 2016 N=20 --> 13
- fluticasone / Generic mfg.
Trial termination: Does Inhaled Busedonide or Fluticasone Impair Adrenal Function? (clinicaltrials.gov) - Sep 8, 2016
P=N/A, N=50, Terminated, Sponsor: HaEmek Medical Center, Israel
N=20 --> 13 Recruiting --> Terminated; recruiting subjects did not start.
- triamcinolone acetonide / Generic mfg.
Trial completion, Enrollment change: Does Intravitreal Injection of Triamcinolone Acetonide Impairs the Adrenal Function (clinicaltrials.gov) - Sep 8, 2016
P=N/A, N=28, Completed, Sponsor: HaEmek Medical Center, Israel
Recruiting --> Terminated; recruiting subjects did not start. Recruiting --> Completed | N=50 --> 28
- Solu-Cortef (hydrocortisone sodium succinate injection) / Pfizer
Phase classification: Comparison of Cortisol Pump With Standard Treatment for Congenital Adrenal Hyperplasia (clinicaltrials.gov) - Apr 21, 2016
P2, N=8, Active, not recruiting, Sponsor: National Institutes of Health Clinical Center (CC)
Recruiting --> Completed | N=50 --> 28 Phase classification: P1/2 --> P2
- dexamethasone injection / Generic mfg.
Enrollment change, Trial withdrawal, Surgery: The Effect of Dexamethasone on Cortisol Levels in Patients Undergoing Thyroid Surgery (clinicaltrials.gov) - Apr 19, 2016
P4, N=0, Withdrawn, Sponsor: St. Paul's Hospital, Canada
Phase classification: P1/2 --> P2 N=30 --> 0 | Recruiting --> Withdrawn
- Solu-Cortef (hydrocortisone sodium succinate injection) / Pfizer
Trial completion, Enrollment change: STRIPES: Steroid Use in Pediatric Fluid and Vasoactive Infusion Dependent Shock - Pilot Study (clinicaltrials.gov) - Apr 7, 2016
P4, N=57, Completed, Sponsor: Children's Hospital of Eastern Ontario
N=30 --> 0 | Recruiting --> Withdrawn Recruiting --> Completed | N=72 --> 57
- New trial: National Education Programme for Patients With Chronic Adrenal Insufficiency (clinicaltrials.gov) - Mar 1, 2016
P=N/A, N=450, Recruiting, Sponsor: Wuerzburg University Hospital
- prednisone / Generic mfg.
New P2 trial: Vapreda: Vaginal Prednisone Administration for Prevention of Adrenal Crisis (clinicaltrials.gov) - Feb 24, 2016
P2, N=12, Not yet recruiting, Sponsor: Wuerzburg University Hospital
- Enrollment change: Allogeneic Bone Marrow Transplant for Inherited Metabolic Disorders (clinicaltrials.gov) - Jan 25, 2016
P2, N=46, Active, not recruiting, Sponsor: Masonic Cancer Center, University of Minnesota
Recruiting --> Completed | N=72 --> 57 N=66 --> 46
- Enrollment change, Trial withdrawal, Metastases: MT2014-14 IT-MSC for Advanced Cerebral Adrenoleukodystrophy (cALD) (clinicaltrials.gov) - Jan 25, 2016
P1, N=0, Withdrawn, Sponsor: Masonic Cancer Center, University of Minnesota
N=66 --> 46 N=18 --> 0 | Not yet recruiting --> Withdrawn
- Solu-Cortef (hydrocortisone sodium succinate injection) / Pfizer
Enrollment closed: Comparison of Cortisol Pump With Standard Treatment for Congenital Adrenal Hyperplasia (clinicaltrials.gov) - Dec 21, 2015
P1/2, N=8, Active, not recruiting, Sponsor: National Institutes of Health Clinical Center (CC)
N=18 --> 0 | Not yet recruiting --> Withdrawn Recruiting --> Active, not recruiting
- Solu-Cortef (hydrocortisone sodium succinate injection) / Pfizer
Enrollment closed, Trial primary completion date: Continuous Subcutaneous Hydrocortisone Infusion In Addison's Disease and Type 1 Diabetes (clinicaltrials.gov) - Dec 4, 2015
P2, N=10, Active, not recruiting, Sponsor: Haukeland University Hospital
Recruiting --> Active, not recruiting Recruiting --> Active, not recruiting | Trial primary completion date: Dec 2015 --> Dec 2016
- Trial completion, Enrollment change: Value of 25 mcg Cortrosyn Stimulation Test (clinicaltrials.gov) - Nov 9, 2015
P=N/A, N=23, Completed, Sponsor: The Cleveland Clinic
Recruiting --> Active, not recruiting | Trial primary completion date: Dec 2015 --> Dec 2016 Recruiting --> Completed | N=60 --> 23
- Enrollment closed, Trial primary completion date: Allogeneic Bone Marrow Transplant for Inherited Metabolic Disorders (clinicaltrials.gov) - Apr 25, 2015
P2, N=66, Active, not recruiting, Sponsor: Masonic Cancer Center, University of Minnesota
Recruiting --> Completed | N=60 --> 23 Recruiting --> Active, not recruiting | Trial primary completion date: Nov 2014 --> Jun 2015
- ursodeoxycholic acid / Generic mfg.
Trial termination: Study of Bile Acids in Patients With Peroxisomal Disorders (clinicaltrials.gov) - Apr 19, 2015
P=N/A, N=25, Terminated, Sponsor: Children's Hospital Research Foundation University of Cincinnati
Recruiting --> Active, not recruiting | Trial primary completion date: Nov 2014 --> Jun 2015 Not yet recruiting --> Terminated
- Solu-Cortef (hydrocortisone sodium succinate injection) / Pfizer
Trial primary completion date: Continuous Subcutaneous Hydrocortisone Infusion In Addison's Disease and Type 1 Diabetes (clinicaltrials.gov) - Apr 14, 2015
P2, N=10, Recruiting, Sponsor: Haukeland University Hospital
Not yet recruiting --> Terminated Trial primary completion date: Jun 2014 --> Dec 2015
- hydrocortisone / Generic mfg.
Trial termination, Trial primary completion date: CSM (clinicaltrials.gov) - Apr 14, 2015
P4, N=32, Terminated, Sponsor: Max-Planck-Institute of Psychiatry
Trial primary completion date: Jun 2014 --> Dec 2015 Enrolling by invitation --> Terminated | Trial primary completion date: Jul 2011 --> Mar 2015; Insufficient recruitment of suitable patients.
- New P1 trial, Metastases: MT2014-14 IT-MSC for Advanced Cerebral Adrenoleukodystrophy (cALD) (clinicaltrials.gov) - Apr 7, 2015
P1, N=18, Not yet recruiting, Sponsor: Masonic Cancer Center, University of Minnesota
- Solu-Cortef (hydrocortisone sodium succinate injection) / Pfizer
Trial primary completion date: Comparison of Cortisol Pump With Standard Treatment for Congenital Adrenal Hyperplasia (clinicaltrials.gov) - Mar 11, 2015
P1/2, N=8, Recruiting, Sponsor: National Institutes of Health Clinical Center (CC)
Enrolling by invitation --> Terminated | Trial primary completion date: Jul 2011 --> Mar 2015; Insufficient recruitment of suitable patients. Trial primary completion date: Dec 2016 --> Jun 2017