Adenoid Cystic Carcinoma MOAs - LARVOL Sigma

Adenoid Cystic Carcinoma

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44 Mechanisms of Action


Phase N/A 1 2 3 4 Products		0	2										4										6										8										10										12										14										16										18										20



VEGFR-2 inhib




Tubulin inhib




Immunostimulant




VEGFR inhib




AKT inhib




EGFR inhib




CD8 T-cell agon




PDGFR inhib




c-KIT inhib




µ-opioid agon




AKT inhib




Bcl2 inhib




Bcl2 inhib




DNA cross linking agent




HIF-1 inhib




Histamine H1 receptor antag




TNFα inhib




Tubulin inhib




HER2 inhib




IL-6 inhib




Protease inhib




TIE-2 inhib




mTOR inhib




ATP stim




CD13 mod




CD4 T cell mod




CXCL12 inhib




Capillary permeability mod




EPH receptor inhib




FGFR2 inhib




Farnesyl transferase inhib




Fyn inhib




GM-CSF agon




GM-CSF agon




HIF-1 inhib




IL-10 stim




IL-12 inhib




IL-1β inhib




IL-2 stim




IL-6 inhib




PI3K inhib




Proteasome inhib




STAT3 inhib




Vascular disrupting agent




iNOS inhib