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32 Companies |
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26 Products |
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26 Products |
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24 Mechanisms of Action |
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0 Trials |
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776 News |
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- NN1213 / Novo Nordisk
Enrollment change, Trial termination, Trial primary completion date: Studies of Acute Lung Injury (ALI) and Acute Respiratory Distress Syndrome (clinicaltrials.gov) - Oct 6, 2015
P1, N=28, Terminated, Sponsor: Northern State Medical University
N=40 --> 28 | Active, not recruiting --> Terminated | Trial primary completion date: Dec 2012 --> Sep 2014; Inability to recruit the patients due to the short supply and changed local hospital protocol
- Trial completion, Enrollment change, Trial primary completion date: Prophylactic Continuous Positive Airway Pressure (CPAP) in Delivery Room, in the Prevention of Transient Tachypnea of Newborn (TTN): A Randomized Controlled Trial (clinicaltrials.gov) - Oct 6, 2015
P=N/A, N=138, Completed, Sponsor: New York Hospital Queens
N=40 --> 28 | Active, not recruiting --> Terminated | Trial primary completion date: Dec 2012 --> Sep 2014; Inability to recruit the patients due to the short supply and changed local hospital protocol Recruiting --> Completed | N=400 --> 138 | Trial primary completion date: Dec 2011 --> Jan 2013
- New trial: Prognosis of Hematological Cancer Patient Underwent Mechanical Ventillation (clinicaltrials.gov) - Sep 29, 2015
P=N/A, N=50, Completed, Sponsor: Mansoura University
- dexamethasone injection / Generic mfg.
Trial primary completion date: DEXA-ARDS: Efficacy Study of Dexamethasone to Treat the Acute Respiratory Distress Syndrome (clinicaltrials.gov) - Sep 25, 2015
P4, N=314, Recruiting, Sponsor: Dr. Negrin University Hospital
Recruiting --> Completed | N=400 --> 138 | Trial primary completion date: Dec 2011 --> Jan 2013 Trial primary completion date: Jun 2015 --> Dec 2016
- Trial primary completion date: Physiological Study of Low-frequency HFO/HFO-TGI and High-frequency HFO (clinicaltrials.gov) - Sep 24, 2015
P1, N=16, Recruiting, Sponsor: University of Athens
Trial primary completion date: Jun 2015 --> Dec 2016 Trial primary completion date: Jul 2015 --> Dec 2015
- Trial primary completion date: Pulmonary Pathophysiology and Inflammatory Response in Patients Treated With Ecmo for Severe Respiratory Failure (clinicaltrials.gov) - Sep 24, 2015
P=N/A, N=40, Recruiting, Sponsor: Karolinska University Hospital
Trial primary completion date: Jul 2015 --> Dec 2015 Trial primary completion date: Dec 2015 --> Dec 2016
- | Trial completion, Trial initiation date, Trial primary completion date: Trial on Treatment With Inhaled Furosemide of Preterm and Term Neonates With Transient Tachypnoea (clinicaltrials.gov) - Sep 24, 2015
P2, N=20, Completed, Sponsor: University of Cologne
Trial primary completion date: Dec 2015 --> Dec 2016 Recruiting --> Completed | Initiation date: Mar 2013 --> Jan 2012 | Trial primary completion date: Mar 2015 --> Jul 2015
- Trial termination: Assessment of the Effectivity of Total-face Mask for Noninvasive Ventilation During Acute Respiratory Failure (clinicaltrials.gov) - Sep 16, 2015
P4, N=300, Terminated, Sponsor: Corporacion Parc Tauli
Recruiting --> Completed | Initiation date: Mar 2013 --> Jan 2012 | Trial primary completion date: Mar 2015 --> Jul 2015 Suspended --> Terminated; Very low rate of recruitment anticipated futility of pursuing the study
- Trial completion, Surgery: High Flow Nasal Oxygen Therapy for Hypoxemy After Cardiac Surgery (clinicaltrials.gov) - Sep 14, 2015
P=N/A, N=90, Completed, Sponsor: Nantes University Hospital
Suspended --> Terminated; Very low rate of recruitment anticipated futility of pursuing the study Recruiting --> Completed
- New trial, Surgery: CURAREA: Monitoring in Intensive Care Unit of Neuromuscular Blocking Agents Used for Acute Respiratory Distress Syndrome After Cardiothoracic Surgery (clinicaltrials.gov) - Sep 14, 2015
P=N/A, N=82, Recruiting, Sponsor: Centre Chirurgical Marie Lannelongue
- Trial completion, Trial primary completion date, HEOR: ALTOS: Evaluating Health Outcomes and QOL After ALI Among Participants of the ALTA, OMEGA, EDEN, and SAILS ARDS Network Trials (clinicaltrials.gov) - Sep 1, 2015
P=N/A, N=922, Completed, Sponsor: Johns Hopkins University
Recruiting --> Completed Active, not recruiting --> Completed | Trial primary completion date: Apr 2015 --> Oct 2014
- Trial completion, Trial primary completion date: Long-Term Results in Mechanically Ventilated Individuals With Acute Lung Injury/Acute Respiratory Distress Syndrome (clinicaltrials.gov) - Sep 1, 2015
P=N/A, N=520, Completed, Sponsor: Johns Hopkins University
Active, not recruiting --> Completed | Trial primary completion date: Apr 2015 --> Oct 2014 Active, not recruiting --> Completed | Trial primary completion date: Dec 2015 --> Oct 2012
- Phase classification: VVCCO2R: Venovenous CO2 Removal (VVCO2R) in Patients With COPD and Acute Respiratory Failure (clinicaltrials.gov) - Aug 26, 2015
P=N/A, N=2, Terminated, Sponsor: The University of Texas Medical Branch, Galveston
Active, not recruiting --> Completed | Trial primary completion date: Dec 2015 --> Oct 2012 Phase classification: P1/2 --> P=N/A
- Trial completion: PARSA: Pulmonary And Renal Support During Acute Respiratory Distress Syndrome (clinicaltrials.gov) - Aug 26, 2015
P3, N=11, Completed, Sponsor: H
Phase classification: P1/2 --> P=N/A Recruiting --> Completed
- Biomarker, Enrollment change, Trial withdrawal, Trial primary completion date: BALI: Genetic Variability and Biomarkers in Children With Acute Lung Injury (clinicaltrials.gov) - Aug 24, 2015
P=N/A, N=0, Withdrawn, Sponsor: Medical College of Wisconsin
Recruiting --> Completed N=2450 --> 0 | Enrolling by invitation --> Withdrawn | Trial primary completion date: Nov 2011 --> Jun 2013
- || Trial primary completion date: RINO: Impact of Nasal High-flow vs Venturi Mask Oxygen Therapy on Weaning Outcome: a Multicenter, Randomized, Controlled Trial (clinicaltrials.gov) - Aug 21, 2015
P=N/A, N=500, Recruiting, Sponsor: Catholic University of the Sacred Heart
N=2450 --> 0 | Enrolling by invitation --> Withdrawn | Trial primary completion date: Nov 2011 --> Jun 2013 Trial primary completion date: Jun 2015 --> Aug 2016
- ||| Aerosurf (lucinactant) / Windtree Therap, Dompe, Esteve, Lee's Pharm
Enrollment change, Trial primary completion date: Trial to Assess the Safety and Tolerability of Lucinactant for Inhalation in Premature Neonates (clinicaltrials.gov) - Aug 19, 2015
P2, N=80, Recruiting, Sponsor: Discovery Laboratories, Inc.
Trial primary completion date: Jun 2015 --> Aug 2016 N=48 --> 80 | Trial primary completion date: Mar 2015 --> Oct 2015
- Trial completion, Enrollment change: The Use of Heliox Via Nasal CPAP to Prevent Early CPAP Failure in Premature Infants: A Feasibility Study (clinicaltrials.gov) - Aug 19, 2015
P=N/A, N=13, Completed, Sponsor: Hawaii Pacific Health
N=48 --> 80 | Trial primary completion date: Mar 2015 --> Oct 2015 Recruiting --> Completed | N=20 --> 13
- Enrollment change, Trial withdrawal: Safety Study of Inhaled Saline in Acute Lung Injury (clinicaltrials.gov) - Aug 17, 2015
P1, N=0, Withdrawn, Sponsor: Mayo Clinic
Recruiting --> Completed | N=20 --> 13 N=15 --> 0 | Recruiting --> Withdrawn
- Trial completion, Trial primary completion date, Intubation: HIGHER: High Flow Nasal Canula Oxygen Helps Preoxygenate ARDS Patients (clinicaltrials.gov) - Aug 14, 2015
P=N/A, N=50, Completed, Sponsor: H
N=15 --> 0 | Recruiting --> Withdrawn Recruiting --> Completed | Trial primary completion date: Aug 2014 --> Aug 2015
- Trial primary completion date: The Oscillation for Acute Respiratory Distress Syndrome (ARDS) Treated Early (OSCILLATE) Trial (clinicaltrials.gov) - Aug 13, 2015
P3, N=548, Terminated, Sponsor: Canadian Critical Care Trials Group
Recruiting --> Completed | Trial primary completion date: Aug 2014 --> Aug 2015 Trial primary completion date: Dec 2013 --> Sep 2012
- Trial primary completion date: Variable Ventilation During Acute Respiratory Failure (clinicaltrials.gov) - Aug 13, 2015
P1, N=16, Recruiting, Sponsor: Boston Medical Center
Trial primary completion date: Dec 2013 --> Sep 2012 Trial primary completion date: Jul 2015 --> Jul 2016
- Trial suspension, Trial primary completion date: NHFOV Versus NCPAP to Prevent Exubation Failure (clinicaltrials.gov) - Aug 13, 2015
P=N/A, N=20, Suspended, Sponsor: University of Manitoba
Trial primary completion date: Jul 2015 --> Jul 2016 Not yet recruiting --> Suspended | Trial primary completion date: Dec 2013 --> Dec 2015
- New trial: FLIPI: Flow-cycled Ventilation in Preterm Infants (clinicaltrials.gov) - Aug 13, 2015
P=N/A, N=10, Not yet recruiting, Sponsor: Central Manchester University Hospitals NHS Foundation Trust
- Trial completion, Trial initiation date: STANDARDS: Stratification of the Acute Respiratory Distress Syndrome (clinicaltrials.gov) - Aug 11, 2015
P=N/A, N=600, Completed, Sponsor: Dr. Negrin University Hospital
Not yet recruiting --> Suspended | Trial primary completion date: Dec 2013 --> Dec 2015 Recruiting --> Completed | Initiation date: May 2014 --> Jan 2014
- Trial completion, Enrollment change, Trial primary completion date: Impact of Different Modes of Noninvasive Ventilation on Regional Oximetry and Hemodynamics in Premature Newborn (clinicaltrials.gov) - Aug 11, 2015
P=N/A, N=10, Completed, Sponsor: University of Manitoba
Recruiting --> Completed | Initiation date: May 2014 --> Jan 2014 Recruiting --> Completed | N=20 --> 10 | Trial primary completion date: Dec 2014 --> Aug 2014
- ketamine / Generic mfg.
Trial completion: Pharmacokinetic Alterations During ECMO (clinicaltrials.gov) - Aug 11, 2015
P=N/A, N=20, Completed, Sponsor: Columbia University
Recruiting --> Completed | N=20 --> 10 | Trial primary completion date: Dec 2014 --> Aug 2014 Active, not recruiting --> Completed
- Enrollment open: Electrical Impedance Imaging of Patients on Mechanical Ventilation (clinicaltrials.gov) - Aug 6, 2015
P=N/A, N=4, Recruiting, Sponsor: Colorado State University
Active, not recruiting --> Completed Not yet recruiting --> Recruiting
- Trial primary completion date: Assessing Respiratory Variability During Mechanical Ventilation in Acute Lung Injury (ALI) (clinicaltrials.gov) - Jul 21, 2015
P=N/A, N=20, Recruiting, Sponsor: Boston Medical Center
Not yet recruiting --> Recruiting Trial primary completion date: Dec 2016 --> Dec 2019
- Biomarker, Trial primary completion date: Biomarkers of Lung Injury With Low Tidal Volume Ventilation Compared With Airway Pressure Release Ventilation (clinicaltrials.gov) - Jul 21, 2015
P=N/A, N=16, Suspended, Sponsor: Boston Medical Center
Trial primary completion date: Dec 2016 --> Dec 2019 Trial primary completion date: Jun 2011 --> Jun 2016
- | Trial completion, Trial primary completion date: Sedation Management in Pediatric Patients With Acute Respiratory Failure (The RESTORE Study) (clinicaltrials.gov) - Jul 15, 2015
P3, N=2449, Completed, Sponsor: University of Pennsylvania
Trial primary completion date: Jun 2011 --> Jun 2016 Enrolling by invitation --> Completed | Trial primary completion date: Dec 2012 --> Dec 2013
- Enrollment change, Trial termination: Different Lipid Emulsions in Acute Lung Injury Patients (clinicaltrials.gov) - Jul 13, 2015
P4, N=1, Terminated, Sponsor: B. Braun Melsungen AG
Enrolling by invitation --> Completed | Trial primary completion date: Dec 2012 --> Dec 2013 N=30 --> 1 | Recruiting --> Terminated; Low recruitment
- Enrollment closed, Trial primary completion date: NUTRIREA2: Impact of Early Enteral vs. Parenteral Nutrition on Mortality in Patients Requiring Mechanical Ventilation and Catecholamines (clinicaltrials.gov) - Jul 10, 2015
P=N/A, N=2854, Active, not recruiting, Sponsor: Centre Hospitalier Departemental Vendee
N=30 --> 1 | Recruiting --> Terminated; Low recruitment Recruiting --> Active, not recruiting | Trial primary completion date: Mar 2016 --> Jul 2015
- ||| Enrollment closed: LIPS-B: Lung Injury Prevention Study With Budesonide and Beta (clinicaltrials.gov) - Jul 9, 2015
P2, N=60, Active, not recruiting, Sponsor: Mayo Clinic
Recruiting --> Active, not recruiting | Trial primary completion date: Mar 2016 --> Jul 2015 Recruiting --> Active, not recruiting
- Trial completion, Enrollment change, Trial primary completion date: Laryngeal Mask Airway (LMA) for Surfactant Administration in Neonates (clinicaltrials.gov) - Jul 9, 2015
P=N/A, N=102, Completed, Sponsor: University of Minnesota - Clinical and Translational Science Institute
Recruiting --> Active, not recruiting Recruiting --> Completed | N=144 --> 102 | Trial primary completion date: May 2016 --> Apr 2015
- Trial primary completion date: Comparing Weaning of Nasal Continuous Positive Airway Pressure (CPAP) From Preterm Infants (clinicaltrials.gov) - Jul 8, 2015
P=N/A, N=70, Recruiting, Sponsor: Maimonides Medical Center
Recruiting --> Completed | N=144 --> 102 | Trial primary completion date: May 2016 --> Apr 2015 Trial primary completion date: Dec 2014 --> Dec 2015
- New trial: The Role of IL33/ST2 Axis in ARDS Patients (clinicaltrials.gov) - Jul 8, 2015
P=N/A, N=200, Recruiting, Sponsor: Hospital Universitari Vall d'Hebron Research Institute
- Enrollment open: Comparison of Three Scores for Ultrasound Assessment and Monitoring of Pulmonary Aeration (clinicaltrials.gov) - Jul 8, 2015
P=N/A, N=100, Recruiting, Sponsor: Centre hospitalier de l'Universit
Trial primary completion date: Dec 2014 --> Dec 2015 Not yet recruiting --> Recruiting
- New trial: Prevention of Severe Acute Respiratory Failure in Patients With PROOFCheck (clinicaltrials.gov) - Jul 2, 2015
P=N/A, N=3459, Not yet recruiting, Sponsor: Albert Einstein College of Medicine of Yeshiva University
- Trial completion, Enrollment change, Trial primary completion date: Comparing Bubble and Ventilator Nasal CPAP in Preterm Infants (clinicaltrials.gov) - Jun 30, 2015
P=N/A, N=18, Completed, Sponsor: Maimonides Medical Center
Not yet recruiting --> Recruiting Recruiting --> Completed | N=40 --> 18 | Trial primary completion date: Jun 2014 --> Oct 2014
- Enrollment open: Validation of a Simple Approach to Estimate Alveolar Recruitability in ARDS Patients (clinicaltrials.gov) - Jun 28, 2015
P=N/A, N=30, Recruiting, Sponsor: St. Michael's Hospital, Toronto
Recruiting --> Completed | N=40 --> 18 | Trial primary completion date: Jun 2014 --> Oct 2014 Not yet recruiting --> Recruiting
- Trial primary completion date: Weaning of Nasal Continuous Positive Airway Pressure (CPAP) in Premature Infants (clinicaltrials.gov) - Jun 26, 2015
P=N/A, N=300, Recruiting, Sponsor: Aarhus University Hospital
Not yet recruiting --> Recruiting Trial primary completion date: Sep 2014 --> Dec 2016
- Curosurf (poractant alfa) / Chiesi
New trial: Efficacy of a New Technique -"IN-REC-SUR-E"- in Preterm Neonates With RDS (clinicaltrials.gov) - Jun 26, 2015
P=N/A, N=206, Not yet recruiting, Sponsor: Catholic University of the Sacred Heart
- Trial completion: Effects of Chest Wall Elastance on Pulmonary Mechanics of Acute Respiratory Failure (ARF) (clinicaltrials.gov) - Jun 24, 2015
P=N/A, N=12, Completed, Sponsor: Southeast University, China
Trial primary completion date: Sep 2014 --> Dec 2016 Not yet recruiting --> Completed
- Trial completion, Trial primary completion date, Compliance: APT: Standard Treatment Compliance of Participants, Effectiveness and Prognosis in Acute Respiratory Distress Syndrome (clinicaltrials.gov) - Jun 24, 2015
P4, N=134, Completed, Sponsor: Southeast University, China
Not yet recruiting --> Completed Recruiting --> Completed | Trial primary completion date: Dec 2016 --> Jun 2015
- Trial primary completion date: Prediction of Neonatal Respiratory Distress Syndrome in Preterm Fetuses by Assessment of Fetal Lung Volume by Vocal and Pulmonary Artery Resistance Index a Pilot Study (clinicaltrials.gov) - Jun 23, 2015
P=N/A, N=80, Recruiting, Sponsor: Ain Shams University
Recruiting --> Completed | Trial primary completion date: Dec 2016 --> Jun 2015 Trial primary completion date: Jun 2015 --> Dec 2015
- Trial primary completion date: The Use of Maternal Serum Unconjugated Estriol for Monitoring the Prevention of Neonatal Respiratory Distress Syndrome (clinicaltrials.gov) - Jun 23, 2015
P4, N=200, Recruiting, Sponsor: Indiana University
Trial primary completion date: Jun 2015 --> Dec 2015 Trial primary completion date: Jul 2015 --> Jul 2017
- New trial, Surgery: ALI: Acute Lung Injury After Cardiac Surgery: Pathogenesis (clinicaltrials.gov) - Jun 20, 2015
P=N/A, N=50, Completed, Sponsor: Aalborg Universitetshospital
- Biomarker, Trial primary completion date: IFRA2: Validation of the Percentage of Alveolar Fibrocyte as Biomarker During ARDS (clinicaltrials.gov) - Jun 15, 2015
P=N/A, N=84, Recruiting, Sponsor: Assistance Publique - H
Trial primary completion date: Jul 2015 --> Jul 2017 Trial primary completion date: Aug 2015 --> Nov 2015
- Trial primary completion date: Enteral Feeding Composition and Acute Respiratory Failure (clinicaltrials.gov) - Jun 11, 2015
P2/3, N=42, Recruiting, Sponsor: Zahra Vahdat Shariatpanahi
Trial primary completion date: Aug 2015 --> Nov 2015 Trial primary completion date: May 2015 --> Sep 2015