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32 Companies |
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26 Products |
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26 Products |
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24 Mechanisms of Action |
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0 Trials |
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776 News |
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- Trial termination: Inhaled Prostaglandin E1 (IPGE1) for Hypoxemic Respiratory Failure (NHRF) (clinicaltrials.gov) - Jul 15, 2012
P2, N=7, Terminated, Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting --> Terminated; The study was halted due to futility concerns based on the unmet benchmarks as specified in the pilot study protocol.
- Enrollment change: Inhaled Prostaglandin E1 (IPGE1) for Hypoxemic Respiratory Failure (NHRF) (clinicaltrials.gov) - Jul 15, 2012
P2, N=7, Terminated, Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting --> Terminated; The study was halted due to futility concerns based on the unmet benchmarks as specified in the pilot study protocol. N=50 --> 7
- New P1 trial: A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of an Intravenous Infusion of GW328267X in Healthy Volunteers (clinicaltrials.gov) - Jul 12, 2012
P1, N=3, Completed, Sponsor: GlaxoSmithKline
- Enrollment open: Early Use of Noninvasive Positive Pressure Ventilation for Intro-pulmonary Acute Lung Injury (clinicaltrials.gov) - Jul 4, 2012
P=N/A, N=200, Recruiting, Sponsor: Beijing Hospital
N=50 --> 7 Not yet recruiting --> Recruiting
- Turnobi (L-citrulline intravenous) / Asklepion Pharma
Trial initiation date: Citrulline in Severe Sepsis (clinicaltrials.gov) - Jun 18, 2012
P2, N=75, Recruiting, Sponsor: Vanderbilt University
Not yet recruiting --> Recruiting Initiation date: Jan 2012 --> Aug 2012
- Trial termination: Predictors for Responsiveness to Corticosteroid in Patients With Early Acute Respiratory Distress Syndrome (clinicaltrials.gov) - Jun 9, 2012
P=N/A, N=20, Terminated, Sponsor: Samsung Medical Center
Initiation date: Jan 2012 --> Aug 2012 Recruiting --> Terminated
- Enrollment change: Predictors for Responsiveness to Corticosteroid in Patients With Early Acute Respiratory Distress Syndrome (clinicaltrials.gov) - Jun 9, 2012
P=N/A, N=20, Terminated, Sponsor: Samsung Medical Center
Recruiting --> Terminated N=90 --> 20
- Surgery: High Flow Nasal Oxygen Therapy for Hypoxemy After Cardiac Surgery (clinicaltrials.gov) - Jun 7, 2012
P=N/A, N=98, Recruiting, Sponsor: Nantes University Hospital
- New P2 trial: MISurf Versus InSurE. A Comparison of Minimally Invasive Surfactant Application Techniques in Preterm Infants (clinicaltrials.gov) - Jun 6, 2012
P2, N=40, Not yet recruiting, Sponsor: Hamilton Health Sciences Corporation
- azithromycin / Generic mfg.
Trial completion: Trial II of Lung Protection With Azithromycin in the Preterm Infant (clinicaltrials.gov) - Jun 6, 2012
P2, N=220, Completed, Sponsor: University of Kentucky
N=90 --> 20 Active, not recruiting --> Completed
- Trial completion: Estimation of Intrinsic Positive End-Expiratory Pressure (PEEP) in Acute Respiratory Distress Syndrome (ARDS) (clinicaltrials.gov) - May 29, 2012
P=N/A, N=6, Completed, Sponsor: Texas Tech University Health Sciences Center
Active, not recruiting --> Completed Active, not recruiting --> Completed
- dexmedetomidine / Generic mfg.
Clinical: Testing the Feasibility of Patient Controlled Sedation for Ventilated ICU Patients (clinicaltrials.gov) - May 24, 2012
P1/2, N=40, Recruiting, Sponsor: University of Minnesota - Clinical and Translational Science Institute
- Curosurf (poractant alfa) / Chiesi
Trial initiation date, Compliance: Comparison in Pulmonary Compliance Between Curosurf and Survanta in Preterm Infants With Respiratory Distress Syndrome (clinicaltrials.gov) - May 16, 2012
P=N/A, N=0, Withdrawn, Sponsor: University of Michigan
Active, not recruiting --> Completed Initiation date: Mar 2012 --> Jun 2012
- New P4 trial, Metastases: Diffuse Acute Respiratory Distress Syndrome (ARDS), Recruitment Maneuver, and sRAGE (DAMAGE Study) (clinicaltrials.gov) - May 15, 2012
P4, N=24, Completed, Sponsor: University Hospital, Clermont-Ferrand
- ||||| New P2 trial, IO biomarker: The Safety, Tolerability, PK and PD of GSK2586881 in Patients With Acute Lung Injury (clinicaltrials.gov) - May 10, 2012
P2, N=65, Recruiting, Sponsor: GlaxoSmithKline
- New P3 trial: "VARIABLE-PSV" Study (clinicaltrials.gov) - Apr 17, 2012
P3, N=20, Completed, Sponsor: University Hospital, Montpellier
- || Curosurf (poractant alfa) / Chiesi
Enrollment change: Observational Study on the Prophylactic Use of Curosurf in Neonatal Respiratory Distress Syndrome (RDS) (clinicaltrials.gov) - Apr 4, 2012
P=N/A, N=972, Completed, Sponsor: Chiesi Farmaceutici S.p.A.
Initiation date: Mar 2012 --> Jun 2012 N=600 --> 972
- Enrollment open: Pulmonary Pathophysiology and Inflammatory Response in Patients Treated With Ecmo for Severe Respiratory Failure (clinicaltrials.gov) - Apr 4, 2012
P=N/A, N=40, Recruiting, Sponsor: Karolinska University Hospital
N=600 --> 972 Not yet recruiting --> Recruiting
- ||| Curosurf (poractant alfa) / Chiesi
Trial completion: Observational Study on the Prophylactic Use of Curosurf in Neonatal Respiratory Distress Syndrome (RDS) (clinicaltrials.gov) - Apr 4, 2012
P=N/A, N=972, Completed, Sponsor: Chiesi Farmaceutici S.p.A.
Not yet recruiting --> Recruiting Recruiting --> Completed
- New P2 trial: Recruitment on Extravascular Lung Water in Acute Respiratory Distress Syndrome (ARDS) (clinicaltrials.gov) - Mar 11, 2012
P2, N=30, Completed, Sponsor: Chang Gung Memorial Hospital
- Trial completion: Respiratory Mechanics and Pleural Effusion (clinicaltrials.gov) - Mar 6, 2012
P=N/A, N=60, Completed, Sponsor: Policlinico Hospital
Recruiting --> Completed Recruiting --> Completed
- || New P3 trial: PROPPR: Pragmatic, Randomized Optimal Platelet and Plasma Ratios (clinicaltrials.gov) - Mar 4, 2012
P3, N=680, Completed, Sponsor: The University of Texas Health Science Center, Houston
- Clinical: Evaluating the Patient-Ventilator Synchrony During Mechanical Ventilation in Patients With Acute Lung Injury (clinicaltrials.gov) - Feb 28, 2012
P=N/A, N=30, Recruiting, Sponsor: University of Chicago
- | Trial completion: Early Versus Delayed Enteral Feeding to Treat People With Acute Lung Injury or Acute Respiratory Distress Syndrome (The EDEN Study) (clinicaltrials.gov) - Feb 8, 2012
P3, N=1000, Completed, Sponsor: National Heart, Lung, and Blood Institute (NHLBI)
Recruiting --> Completed Active, not recruiting --> Completed
- Trial termination: OLIVIA: Will CPAP Reduce Length Of Respiratory Support In Premature Infants? (clinicaltrials.gov) - Feb 7, 2012
P3, N=126, Terminated, Sponsor: Children's & Women's Health Centre of British Columbia
Active, not recruiting --> Completed Recruiting --> Terminated; Decreasing recruitment
- Enrollment change: OLIVIA: Will CPAP Reduce Length Of Respiratory Support In Premature Infants? (clinicaltrials.gov) - Feb 7, 2012
P3, N=126, Terminated, Sponsor: Children's & Women's Health Centre of British Columbia
Recruiting --> Terminated; Decreasing recruitment N=325 --> 126
- New P3 trial: Patient Comfort During High Flow Nasal Cannula Versus Nasal Continuous Airway Pressure (CPAP) (clinicaltrials.gov) - Feb 1, 2012
P3, N=24, Completed, Sponsor: University Hospital of North Norway
- | New P1/2 trial: Use of PiCCO System in Critically Ill Patients With Septic Shock and Acute Respiratory Distress Syndrome (clinicaltrials.gov) - Feb 1, 2012
P1/2, N=400, Recruiting, Sponsor: Jinhua Central Hospital
- | Enrollment open: Flow-flow ECCO2-R and 4 ml/kg Tidal Volume vs. 6 ml/kg Tidal Volume to Enhance Protection From VILI in Acute Lung Injury (clinicaltrials.gov) - Feb 1, 2012
P3, N=230, Recruiting, Sponsor: University of Turin, Italy
N=325 --> 126 Not yet recruiting --> Recruiting
- || New P3 trial: Flow-flow ECCO2-R and 4 ml/kg Tidal Volume vs. 6 ml/kg Tidal Volume to Enhance Protection From VILI in Acute Lung Injury (clinicaltrials.gov) - Jan 29, 2012
P3, N=230, Recruiting, Sponsor: University of Turin, Italy
- Trial completion: FluBAL: Immuno-virological Characterization of Severe H1N1v Influenza Infection in Bronchoalveolar Lavage (clinicaltrials.gov) - Jan 26, 2012
P=N/A, N=30, Completed, Sponsor: Institut National de la Sant
Not yet recruiting --> Recruiting Recruiting --> Completed
- New P3 trial: The Oscillation for Acute Respiratory Distress Syndrome (ARDS) Treated Early (OSCILLATE) Trial (clinicaltrials.gov) - Jan 8, 2012
P3, N=548, Terminated, Sponsor: Canadian Critical Care Trials Group
- | aspirin / Generic mfg.
New P2 trial: LIPS-A: Lung Injury Prevention Study With Aspirin (clinicaltrials.gov) - Jan 4, 2012
P2, N=400, Recruiting, Sponsor: Ognjen Gajic
- Surgery: Intensive Alveolar Recruitment Protocol After Cardiac Surgery (clinicaltrials.gov) - Dec 20, 2011
P=N/A, N=320, Recruiting, Sponsor: University of Sao Paulo
- | Enrollment open: CALIPSO: Calfactant for Acute Lung Injury in Pediatric Stem Cell Transplant and Oncology Patients (clinicaltrials.gov) - Dec 13, 2011
P2/3, N=140, Recruiting, Sponsor: Penn State University
Recruiting --> Completed Suspended --> Recruiting
- | New P2 trial: High-frequency Oscillatory Ventilation (HFOV) in Preterm Infants With Severe Respiratory Distress Syndrome (RDS) (clinicaltrials.gov) - Dec 12, 2011
P2, N=360, Completed, Sponsor: Zhengzhou Children's Hospital, China
- Enrollment change: Respiratory Mechanics and Pleural Effusion (clinicaltrials.gov) - Dec 6, 2011
P=N/A, N=60, Completed, Sponsor: Policlinico Hospital
Suspended --> Recruiting N=33 --> 60
- rosuvastatin / Generic mfg.
Enrollment change: STIP: Statin Trial for Influenza Patients (clinicaltrials.gov) - Nov 29, 2011
P=N/A, N=7, Terminated, Sponsor: Gordon Bernard
N=33 --> 60 N=2000 --> 7
- Enrollment closed: Effects of Different Assisted Mechanical Ventilation in Acute Lung Injury (ALI)/Acute Respiratory Distress Syndrome (ARDS) Patients (clinicaltrials.gov) - Nov 29, 2011
P=N/A, N=20, Active, not recruiting, Sponsor: Policlinico Hospital
N=2000 --> 7 Recruiting --> Active, not recruiting
- Enrollment closed: Effects of Variable Ventilation on Respiratory System of Acute Respiratory Distress Syndrome (ARDS) Patients (clinicaltrials.gov) - Nov 29, 2011
P=N/A, N=16, Active, not recruiting, Sponsor: Policlinico Hospital
Recruiting --> Active, not recruiting Recruiting --> Active, not recruiting
- Trial completion: How to Predict Lung Recruitment at the Bedside in Patients Affected by Acute Lung Injury/Acute Respiratory Distress Syndrome (ALI/ARDS) (clinicaltrials.gov) - Nov 29, 2011
P=N/A, N=50, Completed, Sponsor: Policlinico Hospital
Recruiting --> Active, not recruiting Recruiting --> Completed
- New P2/3 trial: High Frequency Oscillatory Ventilation for Acute Respiratory Distress Syndrome (ARDS) (clinicaltrials.gov) - Nov 21, 2011
P2/3, N=42, Terminated, Sponsor: University of Athens
- ||| GSK1995057 / GSK
New P1 trial: Safety Study of GSK1995057 Given as Single and Repeat Intravenous Doses in Healthy Subjects. (clinicaltrials.gov) - Nov 20, 2011
P1, N=56, Completed, Sponsor: GlaxoSmithKline
- | Turnobi (L-citrulline intravenous) / Asklepion Pharma
New P2 trial: Citrulline in Severe Sepsis (clinicaltrials.gov) - Nov 16, 2011
P2, N=75, Recruiting, Sponsor: Vanderbilt University
- | New P1/2 trial: Safety, Pk and Anti-inflammatory Effects of CC10 Protein in Premature Infants With Respiratory Distress Syndrome (RDS) (clinicaltrials.gov) - Nov 13, 2011
P1/2, N=22, Completed, Sponsor: Clarassance, Inc.
- Clinical: Extubation Readiness Study in Very Low Birthweight Infants (clinicaltrials.gov) - Nov 9, 2011
P=N/A, N=90, Recruiting, Sponsor: University of Pennsylvania
- |||||||||| New P3 trial: EOLIA: Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome (clinicaltrials.gov) - Nov 9, 2011
P3, N=331, Recruiting, Sponsor: Assistance Publique - H
- Enrollment closed: Proseva: Effect of Prone Positioning on Mortality in Patients With Severe and Persistent Acute Respiratory Distress Syndrome (clinicaltrials.gov) - Nov 7, 2011
P=N/A, N=460, Active, not recruiting, Sponsor: Hospices Civils de Lyon
Recruiting --> Completed Recruiting --> Active, not recruiting
- New P2 trial: Inhaled Prostaglandin E1 (IPGE1) for Hypoxemic Respiratory Failure (NHRF) (clinicaltrials.gov) - Nov 6, 2011
P2, N=7, Terminated, Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
- || New P3 trial: Effect of Enteral Nutrition Support for Critically Ill Patients (clinicaltrials.gov) - Oct 31, 2011
P3, N=84, Terminated, Sponsor: Abbott Nutrition