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32 Companies |
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26 Products |
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26 Products |
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24 Mechanisms of Action |
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0 Trials |
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776 News |
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- | Trial completion: PROPPR: Pragmatic, Randomized Optimal Platelet and Plasma Ratios (clinicaltrials.gov) - Dec 18, 2013
P3, N=680, Completed, Sponsor: The University of Texas Health Science Center, Houston
Recruiting --> Completed
- Turnobi (L-citrulline intravenous) / Asklepion Pharma
Enrollment open: Citrulline in Severe Sepsis (clinicaltrials.gov) - Dec 15, 2013
P2, N=75, Recruiting, Sponsor: Vanderbilt University
Recruiting --> Completed Not yet recruiting --> Recruiting
- Trial termination: High Frequency Oscillatory Ventilation for Acute Respiratory Distress Syndrome (ARDS) (clinicaltrials.gov) - Dec 11, 2013
P2/3, N=42, Terminated, Sponsor: University of Athens
Not yet recruiting --> Recruiting Active, not recruiting --> Terminated; Low rate of enrollment, in conjunction with inability of continuation of funding
- Enrollment change: High Frequency Oscillatory Ventilation for Acute Respiratory Distress Syndrome (ARDS) (clinicaltrials.gov) - Dec 11, 2013
P2/3, N=42, Terminated, Sponsor: University of Athens
Active, not recruiting --> Terminated; Low rate of enrollment, in conjunction with inability of continuation of funding N=204 --> 42
- | Enrollment change: Mechanical Ventilation, Directed by Esophageal Pressure Measurements, in Patients With Acute Lung Injury (clinicaltrials.gov) - Dec 8, 2013
P2/3, N=63, Completed, Sponsor: Beth Israel Deaconess Medical Center
N=204 --> 42 N=200 --> 63
- | Trial completion: Mechanical Ventilation, Directed by Esophageal Pressure Measurements, in Patients With Acute Lung Injury (clinicaltrials.gov) - Dec 8, 2013
P2/3, N=63, Completed, Sponsor: Beth Israel Deaconess Medical Center
N=200 --> 63 Active, not recruiting --> Completed
- Trial initiation date: PRoVENT: Practice of Ventilation in Critically Ill Patients Without ARDS (clinicaltrials.gov) - Nov 26, 2013
P=N/A, N=1000, Not yet recruiting, Sponsor: Marcus J Schultz
Active, not recruiting --> Completed Initiation date: Jan 2014 --> Apr 2014
- Enrollment change: PRoVENT: Practice of Ventilation in Critically Ill Patients Without ARDS (clinicaltrials.gov) - Nov 26, 2013
P=N/A, N=1000, Not yet recruiting, Sponsor: Marcus J Schultz
Initiation date: Jan 2014 --> Apr 2014 N=800 --> 1000
- betamethasone / Generic mfg.
Trial termination: Antepartum Betamethasone Treatment for Prevention of Respiratory Distress in Infants Born by Elective Cesarean Section (clinicaltrials.gov) - Nov 24, 2013
P2/3, N=67, Terminated, Sponsor: Emory University
N=800 --> 1000 Recruiting --> Terminated; Slow enrollment and lack of funds.
- betamethasone / Generic mfg.
Enrollment change: Antepartum Betamethasone Treatment for Prevention of Respiratory Distress in Infants Born by Elective Cesarean Section (clinicaltrials.gov) - Nov 24, 2013
P2/3, N=67, Terminated, Sponsor: Emory University
Recruiting --> Terminated; Slow enrollment and lack of funds. N=400 --> 67
- Trial suspension: CEASE: Comparative Evaluation of Albumin and Starch Effects in Acute Lung Injury (ALI) (clinicaltrials.gov) - Nov 20, 2013
P3, N=60, Suspended, Sponsor: Emory University
N=400 --> 67 Recruiting --> Suspended
- Enrollment change: AMFAS: Study of the Function of Cells Involved in Inflammation in the Lungs of Those With Acute Lung Injury and Sepsis (clinicaltrials.gov) - Nov 20, 2013
P=N/A, N=80, Active, not recruiting, Sponsor: Emory University
Recruiting --> Suspended N=100 --> 80
- Enrollment closed: AMFAS: Study of the Function of Cells Involved in Inflammation in the Lungs of Those With Acute Lung Injury and Sepsis (clinicaltrials.gov) - Nov 20, 2013
P=N/A, N=80, Active, not recruiting, Sponsor: Emory University
N=100 --> 80 Recruiting --> Active, not recruiting
- Enrollment change, Surgery: LAS VEGAS: Local Assessment of Ventilatory Management During General Anesthesia for Surgery (clinicaltrials.gov) - Nov 19, 2013
P=N/A, N=10690, Completed, Sponsor: European Society of Anaesthesiology
Recruiting --> Active, not recruiting N=4800 --> 10690
- Trial completion, Surgery: LAS VEGAS: Local Assessment of Ventilatory Management During General Anesthesia for Surgery (clinicaltrials.gov) - Nov 19, 2013
P=N/A, N=10690, Completed, Sponsor: European Society of Anaesthesiology
N=4800 --> 10690 Recruiting --> Completed
- Enrollment open: Intensive Care - GLObal Study on Severe Acute Respiratory Infection (clinicaltrials.gov) - Nov 13, 2013
P=N/A, N=4000, Recruiting, Sponsor: European Society of Intensive Care Medicine
Recruiting --> Completed Not yet recruiting --> Recruiting
- Biomarker, Enrollment open: IFRA2: Validation of the Percentage of Alveolar Fibrocyte as Biomarker During ARDS (clinicaltrials.gov) - Nov 11, 2013
P=N/A, N=84, Recruiting, Sponsor: Assistance Publique - H
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- TNKASE (tenecteplase) / Roche, Boehringer Ingelheim
Trial withdrawal: Treatment of Acute Respiratory Distress Syndrome With Tenecteplase: A Dose Escalation Pilot Study (clinicaltrials.gov) - Nov 3, 2013
P1, N=0, Withdrawn, Sponsor: Medical Center of Central Georgia
Not yet recruiting --> Recruiting Recruiting --> Withdrawn
- Trial termination: Continuous Positive Airway Pressure (CPAP) Ventilation Using a Novel Full-Face Mask Versus Conventional Helmet (clinicaltrials.gov) - Nov 3, 2013
P=N/A, N=23, Terminated, Sponsor: University of Parma
Recruiting --> Withdrawn Recruiting --> Terminated; Failed to reach expected enrollment by anticipated dates.
- Enrollment change: Continuous Positive Airway Pressure (CPAP) Ventilation Using a Novel Full-Face Mask Versus Conventional Helmet (clinicaltrials.gov) - Nov 3, 2013
P=N/A, N=23, Terminated, Sponsor: University of Parma
Recruiting --> Terminated; Failed to reach expected enrollment by anticipated dates. N=50 --> 23
- TNKASE (tenecteplase) / Roche, Boehringer Ingelheim
Enrollment change: Treatment of Acute Respiratory Distress Syndrome With Tenecteplase: A Dose Escalation Pilot Study (clinicaltrials.gov) - Nov 3, 2013
P1, N=0, Withdrawn, Sponsor: Medical Center of Central Georgia
N=50 --> 23 N=20 --> 0
- Enrollment change: Heliox in Preterm Infants With Respiratory Distress Syndrome (clinicaltrials.gov) - Oct 24, 2013
P=N/A, N=36, Completed, Sponsor: Third Military Medical University
N=20 --> 0 N=60 --> 36
- Trial completion: Heliox in Preterm Infants With Respiratory Distress Syndrome (clinicaltrials.gov) - Oct 24, 2013
P=N/A, N=36, Completed, Sponsor: Third Military Medical University
N=60 --> 36 Recruiting --> Completed
- rosuvastatin / Generic mfg.
Trial termination: SAILS: Statins for Acutely Injured Lungs From Sepsis (clinicaltrials.gov) - Oct 17, 2013
P3, N=745, Terminated, Sponsor: National Heart, Lung, and Blood Institute (NHLBI)
Recruiting --> Completed Recruiting --> Terminated; stopped for futility
- rosuvastatin / Generic mfg.
Enrollment change: SAILS: Statins for Acutely Injured Lungs From Sepsis (clinicaltrials.gov) - Oct 17, 2013
P3, N=745, Terminated, Sponsor: National Heart, Lung, and Blood Institute (NHLBI)
Recruiting --> Terminated; stopped for futility N=1000 --> 745
- Trial termination: OPTI O2: Evaluation of Oxygen Therapy Delivery Systems in Hypoxemic Acute Respiratory Failure (clinicaltrials.gov) - Oct 3, 2013
P=N/A, N=16, Terminated, Sponsor: Nantes University Hospital
N=1000 --> 745 Recruiting --> Terminated; Difficulty of recruitment
- Enrollment change: OPTI O2: Evaluation of Oxygen Therapy Delivery Systems in Hypoxemic Acute Respiratory Failure (clinicaltrials.gov) - Oct 3, 2013
P=N/A, N=16, Terminated, Sponsor: Nantes University Hospital
Recruiting --> Terminated; Difficulty of recruitment N=24 --> 16
- Trial completion, Metastases: Diffuse Acute Respiratory Distress Syndrome (ARDS), Recruitment Maneuver, and sRAGE (DAMAGE Study) (clinicaltrials.gov) - Sep 30, 2013
P4, N=24, Completed, Sponsor: University Hospital, Clermont-Ferrand
N=24 --> 16 Recruiting --> Completed
- Enrollment change, Metastases: Diffuse Acute Respiratory Distress Syndrome (ARDS), Recruitment Maneuver, and sRAGE (DAMAGE Study) (clinicaltrials.gov) - Sep 29, 2013
P4, N=24, Completed, Sponsor: University Hospital, Clermont-Ferrand
Recruiting --> Completed N=30 --> 24
- Enrollment open: IVNICTUS: Early Non Invasive Ventilation in Immuno-compromized Patients With Acute Respiratory Failure. (clinicaltrials.gov) - Sep 16, 2013
P=N/A, N=374, Recruiting, Sponsor: Assistance Publique - H
N=30 --> 24 Not yet recruiting --> Recruiting
- Trial completion, Surgery: SCRIPT: Seattle Cardiorenal Remote Ischemic Preconditioning Trial (clinicaltrials.gov) - Sep 15, 2013
P=N/A, N=90, Completed, Sponsor: Seattle Children's Hospital
Not yet recruiting --> Recruiting Recruiting --> Completed
- Trial completion: Recruitment on Extravascular Lung Water in Acute Respiratory Distress Syndrome (ARDS) (clinicaltrials.gov) - Sep 12, 2013
P2, N=30, Completed, Sponsor: Chang Gung Memorial Hospital
Recruiting --> Completed Recruiting --> Completed
- Trial termination: Clinical Evaluation of a Closed Loop Oxygen Controller for Neonatal Respiratory Care (clinicaltrials.gov) - Sep 9, 2013
P=N/A, N=20, Terminated, Sponsor: University of Utah
Recruiting --> Completed Active, not recruiting --> Terminated; slow enrollment
- Enrollment change: Clinical Evaluation of a Closed Loop Oxygen Controller for Neonatal Respiratory Care (clinicaltrials.gov) - Sep 9, 2013
P=N/A, N=20, Terminated, Sponsor: University of Utah
Active, not recruiting --> Terminated; slow enrollment N=50 --> 20
- Enrollment open: Impact of Different Modes of Noninvasive Ventilation on Regional Oximetry and Hemodynamics in Premature Newborn (clinicaltrials.gov) - Sep 9, 2013
P=N/A, N=20, Recruiting, Sponsor: University of Manitoba
N=50 --> 20 Not yet recruiting --> Recruiting
- | Enrollment open: Different Lipid Emulsions in Acute Lung Injury Patients (clinicaltrials.gov) - Sep 8, 2013
P4, N=30, Recruiting, Sponsor: B. Braun Melsungen AG
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- Trial completion: Low Dose Lung CT Scan for Quantitative Analysis in ARDS Patients (clinicaltrials.gov) - Aug 19, 2013
P=N/A, N=51, Completed, Sponsor: Policlinico Hospital
Not yet recruiting --> Recruiting Not yet recruiting --> Completed
- Curosurf (poractant alfa) / Chiesi
New P4 trial: Effects of Bolus Surfactant Therapy on Peripheral Perfusion Index and Tissue Carbon Monoxide (clinicaltrials.gov) - Aug 14, 2013
P4, N=48, Completed, Sponsor: Ege University
- Enrollment open: Observational Study in Preterm Neonates Who Are Sufficiently Stable on Non-Invasive Ventilatory Support (clinicaltrials.gov) - Aug 12, 2013
P=N/A, N=40, Recruiting, Sponsor: Takeda
Not yet recruiting --> Completed Not yet recruiting --> Recruiting
- Clinical: Intensive Nutrition in Acute Respiratory Distress Syndrome (ARDS): A Clinical Trial (INTACT) (clinicaltrials.gov) - Aug 11, 2013
P=N/A, N=200, Recruiting, Sponsor: University of Illinois at Chicago
- Trial completion: Thoracic Fluid Content and Acute Lung Injury (clinicaltrials.gov) - Aug 11, 2013
P=N/A, N=22, Completed, Sponsor: National Taiwan University Hospital
Not yet recruiting --> Recruiting Not yet recruiting --> Completed
- ||||| Enrollment change: Effect of Inhaled Nitric Oxide in Acute Chest Syndrome (INOSTA Study) (clinicaltrials.gov) - Jul 31, 2013
P2/3, N=100, Completed, Sponsor: Assistance Publique - H
Not yet recruiting --> Completed N=260 --> 100
- Trial completion: Effects of Recruitment Maneuvers in Early Acute Lung Injury (ALI) and Acute Respiratory Distress Syndrome (ARDS) Patients (clinicaltrials.gov) - Jul 31, 2013
P=N/A, N=120, Completed, Sponsor: LUN WEI LIU
N=260 --> 100 Recruiting --> Completed
- ||||||| Trial completion: Effect of Inhaled Nitric Oxide in Acute Chest Syndrome (INOSTA Study) (clinicaltrials.gov) - Jul 31, 2013
P2/3, N=100, Completed, Sponsor: Assistance Publique - H
Recruiting --> Completed Recruiting --> Completed
- Enrollment change, Surgery: Low Tidal Volume and EVLWI During OLV (clinicaltrials.gov) - Jul 23, 2013
P1, N=39, Completed, Sponsor: Dammam University
Recruiting --> Completed N=60 --> 39
- |||| Enrollment open: LIPS-B: Lung Injury Prevention Study With Budesonide and Beta (clinicaltrials.gov) - Jul 23, 2013
P2, N=60, Recruiting, Sponsor: Mayo Clinic
N=60 --> 39 Not yet recruiting --> Recruiting
- Trial completion, Surgery: Low Tidal Volume and EVLWI During OLV (clinicaltrials.gov) - Jul 23, 2013
P1, N=39, Completed, Sponsor: Dammam University
Not yet recruiting --> Recruiting Recruiting --> Completed
- Enrollment open: Lung and Systemic Inflammation in the Critically Ill Patient (clinicaltrials.gov) - Jul 18, 2013
P=N/A, N=18, Recruiting, Sponsor: Rigshospitalet, Denmark
Recruiting --> Completed Not yet recruiting --> Recruiting
- New P3 trial: ELASTANCE: Prospective Physiological Study of Lung Elastance in Recruitment and Derecruitment in Early Onset Mechanically Ventilated ARDS Patients (clinicaltrials.gov) - Jul 11, 2013
P3, N=12, Completed, Sponsor: Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
- Enrollment change: OPTIPEP: Optimization of Arterial Oxygen Transport by Positive End-expiratory Pressure Variation in Acute Respiratory Distress Syndrome (clinicaltrials.gov) - Jul 1, 2013
P=N/A, N=12, Completed, Sponsor: Rennes University Hospital
Not yet recruiting --> Recruiting N=20 --> 12