Acute Myeloid Leukemia, Childhood MOAs

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Acute Myeloid Leukemia, Childhood

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Phase N/A 1 2 3 4 Products	0	3	6	9	12	15	18	21	24	27	30



Purinergic receptor P1 agon




T-cell stim




CD52 inhib




DNA synthesis inhib




JAK2 inhib




GCR agon




AKT inhib




HDAC2 inhib




JAK2 inhib




IL-1 inhib




Tubulin polymerization inhib




Aurora kinase A inhib




CXCL12 inhib




Calcineurin inhib




IFNα 2b stim




IL-2 stim




IMPDH inhib




Immunosuppressant




Nucleoside guanosine analog




PDGFR inhib




T-cell activation inhib




TNF inhib




VEGFR-1 inhib




c-KIT inhib




AKT inhib




Angiogenesis inhib




Anti-inflammatory agent




Apoptosis stim




BRAF inhib




Bone morphogenetic protein receptor type II mod




CD20-targeted radiotherapeutic antibody




CD22-targeted antibody-drug conjugate




CD86 inhib




COX2 inhib




DGAT-1 inhib




Dihydrofolic acid reductase inhib




Farnesyl transferase inhib




GM-CSF agon




GM-CSF agon




HMG-CoA reductase inhib




Hematopoietic stem cell mobilizer




Histamine release inhib




IL-1 inhib




IL-6 mod




Ionizing radiation emitter




Nerve growth factor inhib




PI3K inhib




PPAR α agon




Proteasome inhib




Protein synthesis inhib



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