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44 Companies |
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74 Products |
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74 Products |
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52 Mechanisms of Action |
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4 Trials |
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352 News |
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- Mozobil (plerixafor) / Sanofi
Trial termination: BMTAMD3100: AMD3100 for Sensitizing in Allogeneic Blood or Marrow Transplant for Chemotherapy Resistant Pediatric Acute Leukemia (clinicaltrials.gov) - Apr 3, 2014
P1, N=1, Terminated, Sponsor: Emory University
Recruiting --> Terminated; lack of patient enrollment
- Mozobil (plerixafor) / Sanofi
Enrollment change: BMTAMD3100: AMD3100 for Sensitizing in Allogeneic Blood or Marrow Transplant for Chemotherapy Resistant Pediatric Acute Leukemia (clinicaltrials.gov) - Apr 3, 2014
P1, N=1, Terminated, Sponsor: Emory University
Recruiting --> Terminated; lack of patient enrollment N=12 --> 1
- cyclophosphamide / Generic mfg., busulfan / Generic mfg.
Enrollment closed, Post-transplantation: Combination Chemotherapy, Bone Marrow Transplant, and Post Transplant Cyclophosphamide for Hematologic Cancer (clinicaltrials.gov) - Mar 19, 2014
P2, N=92, Active, not recruiting, Sponsor: Sidney Kimmel Comprehensive Cancer Center
N=12 --> 1 Completed --> Active, not recruiting
- cyclophosphamide / Generic mfg., thiotepa / Generic mfg.
Enrollment change: Total-Body Irradiation and Chemotherapy Followed By Donor Bone Marrow Transplant in Treating Young Patients With Hematologic Cancer (clinicaltrials.gov) - Mar 17, 2014
P2, N=25, Completed, Sponsor: Memorial Sloan-Kettering Cancer Center
Completed --> Active, not recruiting N=50 --> 25
- fludarabine IV / Generic mfg.
Enrollment change: Low-Dose Total-Body Irradiation and Fludarabine Phosphate Followed by Unrelated Donor Stem Cell Transplant in Treating Patients With Fanconi Anemia (clinicaltrials.gov) - Mar 9, 2014
P1, N=2, Active, not recruiting, Sponsor: Fred Hutchinson Cancer Research Center
N=50 --> 25 N=24 --> 2
- Trial withdrawal: Early Detection of Graft-Versus-Host Disease in Patients Undergoing a Donor Bone Marrow Transplant (clinicaltrials.gov) - Mar 5, 2014
P=N/A, N=0, Withdrawn, Sponsor: Mayo Clinic
N=24 --> 2 Active, not recruiting --> Withdrawn
- Enrollment change: Early Detection of Graft-Versus-Host Disease in Patients Undergoing a Donor Bone Marrow Transplant (clinicaltrials.gov) - Mar 5, 2014
P=N/A, N=0, Withdrawn, Sponsor: Mayo Clinic
Active, not recruiting --> Withdrawn N=46 --> 0
- fludarabine IV / Generic mfg., cyclophosphamide / Generic mfg.
Enrollment closed: Chemotherapy and a Donor Natural Killer Cell Infusion in Treating Patients With Relapsed or Persistent Leukemia or Myelodysplastic Syndrome After a Donor Stem Cell Transplant (clinicaltrials.gov) - Mar 4, 2014
P2, N=30, Active, not recruiting, Sponsor: Memorial Sloan-Kettering Cancer Center
N=46 --> 0 Recruiting --> Active, not recruiting
- Trial completion, IO biomarker: Haploidentical Donor Bone Marrow Transplant in Treating Patients With High-Risk Hematologic Cancer (clinicaltrials.gov) - Feb 26, 2014
P2, N=53, Completed, Sponsor: Fred Hutchinson Cancer Research Center
Recruiting --> Active, not recruiting Active, not recruiting --> Completed
- | sirolimus / Generic mfg.
Trial completion: Sirolimus, Tacrolimus, and Methotrexate in Preventing Acute Graft-Versus-Host Disease in Patients With Hematologic Cancer Who Are Undergoing Donor Stem Cell Transplantation (clinicaltrials.gov) - Feb 22, 2014
P1/2, N=0, Completed, Sponsor: Fred Hutchinson Cancer Research Center
Active, not recruiting --> Completed Active, not recruiting --> Completed
- | Thymoglobulin (anti-thymocyte globulin (rabbit)) / Sanofi
Trial completion: Combination Chemotherapy and Antithymocyte Globulin in Reducing Graft-Versus-Host Disease in Patients Undergoing Donor Stem Cell Transplantation For Myelodysplastic Syndrome or Myeloproliferative Disorder (clinicaltrials.gov) - Feb 22, 2014
P1/2, N=0, Completed, Sponsor: Fred Hutchinson Cancer Research Center
Active, not recruiting --> Completed Active, not recruiting --> Completed
- | Neupogen (filgrastim) / Kyowa Kirin, Amgen
Trial completion: Donor Bone Marrow Transplant in Treating Young Patients With Cancer or a Non-Cancerous Disease (clinicaltrials.gov) - Feb 22, 2014
P1/2, N=0, Completed, Sponsor: Fred Hutchinson Cancer Research Center
Active, not recruiting --> Completed Active, not recruiting --> Completed
- | fludarabine IV / Generic mfg., thiotepa / Generic mfg.
Trial completion: Total-Body Irradiation, Thiotepa, and Fludarabine in Treating Young Patients Who Are Undergoing a Donor Stem Cell Transplant for Hematologic Cancer (clinicaltrials.gov) - Feb 22, 2014
P1/2, N=20, Completed, Sponsor: Fred Hutchinson Cancer Research Center
Active, not recruiting --> Completed Active, not recruiting --> Completed
- | Proleukin (aldesleukin) / Merck (MSD), Novartis, Iovance Biotherap
Trial completion: Cellular Adoptive Immunotherapy in Treating Patients With Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Myelodysplastic Syndromes That Relapsed After Donor Stem Cell Transplant (clinicaltrials.gov) - Feb 22, 2014
P1, N=0, Completed, Sponsor: Fred Hutchinson Cancer Research Center
Active, not recruiting --> Completed Active, not recruiting --> Completed
- | mycophenolate mofetil / Generic mfg.
Trial completion, Metastases: Tacrolimus and Mycophenolate Mofetil in Preventing Acute Graft-Versus-Host Disease in Patients With Advanced Hematologic Cancer Who Are Undergoing Donor Stem Cell Transplantation (clinicaltrials.gov) - Feb 22, 2014
P2, N=0, Completed, Sponsor: Fred Hutchinson Cancer Research Center
Active, not recruiting --> Completed Active, not recruiting --> Completed
- | tanespimycin (BMS-722782) / BMS
Trial completion: Tanespimycin in Treating Young Patients With Recurrent or Refractory Leukemia or Solid Tumors (clinicaltrials.gov) - Feb 22, 2014
P1, N=70, Completed, Sponsor: National Cancer Institute (NCI)
Active, not recruiting --> Completed Active, not recruiting --> Completed
- | temozolomide / Generic mfg.
Trial completion: Temozolomide in Treating Young Patients With Refractory or Recurrent Leukemia (clinicaltrials.gov) - Feb 22, 2014
P1, N=16, Completed, Sponsor: Children's Oncology Group
Active, not recruiting --> Completed No longer recruiting --> Completed
- | tanespimycin (BMS-722782) / BMS
Trial completion: 17-N-Allylamino-17-Demethoxygeldanamycin in Treating Young Patients With Relapsed or Refractory Solid Tumors or Leukemia (clinicaltrials.gov) - Feb 22, 2014
P1, N=36, Completed, Sponsor: National Cancer Institute (NCI)
No longer recruiting --> Completed No longer recruiting --> Completed
- | bortezomib / Generic mfg.
Trial completion: Bortezomib in Treating Young Patients With Refractory or Recurrent Leukemia (clinicaltrials.gov) - Feb 22, 2014
P1, N=36, Completed, Sponsor: National Cancer Institute (NCI)
No longer recruiting --> Completed No longer recruiting --> Completed
- | Mylotarg (gemtuzumab ozogamicin) / UCB, PDL, Pfizer
Trial completion: COG-AAML03P1: Gemtuzumab Ozogamicin in Treating Young Patients With Newly Diagnosed Acute Myeloid Leukemia Undergoing Remission Induction and Intensification Therapy (clinicaltrials.gov) - Feb 22, 2014
P2, N=350, Completed, Sponsor: Children's Oncology Group
No longer recruiting --> Completed No longer recruiting --> Completed
- | voriconazole / Generic mfg.
Trial completion: Voriconazole in Preventing Fungal Infections in Children With Neutropenia After Chemotherapy (clinicaltrials.gov) - Feb 22, 2014
P2, N=0, Completed, Sponsor: National Cancer Institute (NCI)
No longer recruiting --> Completed No longer recruiting --> Completed
- | megestrol / Generic mfg.
Trial completion: Cyproheptadine and Megestrol in Preventing Weight Loss in Children With Cachexia Caused By Cancer or Cancer Treatment (clinicaltrials.gov) - Feb 22, 2014
P2, N=70, Completed, Sponsor: University of South Florida
No longer recruiting --> Completed Active, not recruiting --> Completed
- | Neupogen (filgrastim) / Kyowa Kirin, Amgen
Trial completion: Donor Umbilical Cord Blood Transplantation in Treating Patients With Leukemia, Lymphoma, or Nonmalignant Hematologic Disorders (clinicaltrials.gov) - Feb 22, 2014
P2, N=0, Completed, Sponsor: Roswell Park Cancer Institute
Active, not recruiting --> Completed Active, not recruiting --> Completed
- | Istodax (romidepsin) / Astellas, BMS
Trial completion: FR901228 in Treating Children With Refractory or Recurrent Solid Tumors or Leukemia (clinicaltrials.gov) - Feb 22, 2014
P1, N=30, Completed, Sponsor: National Cancer Institute (NCI)
Active, not recruiting --> Completed No longer recruiting --> Completed
- | Leukine (sargramostim) / Partner Therap, Neupogen (filgrastim) / Kyowa Kirin, Amgen
Trial completion: Combination Chemotherapy Followed By Filgrastim or Sargramostim in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Acute Lymphoblastic Leukemia (clinicaltrials.gov) - Feb 22, 2014
P2, N=0, Completed, Sponsor: Roswell Park Cancer Institute
No longer recruiting --> Completed Active, not recruiting --> Completed
- | mitoxantrone / Generic mfg., cytarabine / Generic mfg.
Trial completion: Combination Chemotherapy in Treating Patients With Recurrent or Refractory Leukemia or Lymphoma (clinicaltrials.gov) - Feb 22, 2014
P2, N=3, Completed, Sponsor: Case Comprehensive Cancer Center
Active, not recruiting --> Completed Recruiting --> Completed
- | valacyclovir / Generic mfg.
Trial completion: Valacyclovir in Preventing Cytomegalovirus Infection in Patients Who Are Undergoing Donor Stem Cell Transplantation (clinicaltrials.gov) - Feb 22, 2014
P3, N=0, Completed, Sponsor: Fred Hutchinson Cancer Research Center
Recruiting --> Completed Active, not recruiting --> Completed
- | Ixempra (ixabepilone) - Otsuka, R / Pharm, Allarity Therap, patupilone (EPO 906) / Novartis
Trial completion: Ixabepilone in Treating Young Patients With Solid Tumors or Leukemia That Haven't Responded to Therapy (clinicaltrials.gov) - Feb 22, 2014
P1, N=30, Completed, Sponsor: National Institutes of Health Clinical Center (CC)
Active, not recruiting --> Completed Recruiting --> Completed
- | Mylotarg (gemtuzumab ozogamicin) / UCB, PDL, Pfizer
Trial completion: Monoclonal Antibody Plus Chemotherapy in Treating Young Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndromes (clinicaltrials.gov) - Feb 22, 2014
P1, N=47, Completed, Sponsor: Children's Oncology Group
Recruiting --> Completed No longer recruiting --> Completed
- | Campath (alemtuzumab) / Sanofi
Trial completion: Melphalan, Fludarabine, and Alemtuzumab Followed by Peripheral Stem Cell Transplant in Treating Patients With Hematologic Cancer (clinicaltrials.gov) - Feb 22, 2014
P2, N=51, Completed, Sponsor: Memorial Sloan-Kettering Cancer Center
No longer recruiting --> Completed Active, not recruiting --> Completed
- | Neupogen (filgrastim) / Kyowa Kirin, Amgen
Trial completion: Filgrastim-Treated Donor Peripheral Stem Cell Transplantation in Treating Patients With Acute Leukemia (clinicaltrials.gov) - Feb 22, 2014
P2, N=0, Completed, Sponsor: Fred Hutchinson Cancer Research Center
Active, not recruiting --> Completed Active, not recruiting --> Completed
- | melphalan / Generic mfg., busulfan / Generic mfg.
Trial completion, Metastases: Combination Chemotherapy Followed by Bone Marrow Transplantation in Treating Patients With Advanced Hematologic Cancer (clinicaltrials.gov) - Feb 19, 2014
P2, N=0, Completed, Sponsor: Memorial Sloan-Kettering Cancer Center
Active, not recruiting --> Completed Active, not recruiting --> Completed
- | Zamyl (lintuzumab) / Pfizer, Neupogen (filgrastim) / Kyowa Kirin, Amgen
Trial completion: Chemotherapy Plus Monoclonal Antibody in Treating Patients With Acute Promyelocytic Leukemia (clinicaltrials.gov) - Feb 19, 2014
P2, N=35, Completed, Sponsor: Memorial Sloan-Kettering Cancer Center
Active, not recruiting --> Completed Active, not recruiting --> Completed
- | cytarabine / Generic mfg.
Trial completion, Metastases: Chemotherapy and Monoclonal Antibody Therapy in Treating Patients With Advanced Myeloid Cancer (clinicaltrials.gov) - Feb 19, 2014
P1/2, N=32, Completed, Sponsor: Memorial Sloan-Kettering Cancer Center
Active, not recruiting --> Completed Active, not recruiting --> Completed
- | Synagis (palivizumab) / AbbVie, AstraZeneca, SOBI
Trial completion: Ribavirin With or Without Monoclonal Antibody Therapy in Treating Patients Who Develop RSV Pneumonia Following Peripheral Stem Cell Transplantation (clinicaltrials.gov) - Feb 19, 2014
P3, N=0, Completed, Sponsor: Fred Hutchinson Cancer Research Center
Active, not recruiting --> Completed Active, not recruiting --> Completed
- | Trial completion: Beclomethasone in Treating Patients With Graft-Versus-Host Disease of the Esophagus, Stomach, Small Intestine, or Colon (clinicaltrials.gov) - Feb 19, 2014
P1/2, N=0, Completed, Sponsor: Fred Hutchinson Cancer Research Center
Active, not recruiting --> Completed Active, not recruiting --> Completed
- | Proleukin (aldesleukin) / Merck (MSD), Novartis, Iovance Biotherap, Neupogen (filgrastim) / Kyowa Kirin, Amgen
Trial completion: Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation and Interleukin-2 in Treating Patients With Acute Leukemia (clinicaltrials.gov) - Feb 19, 2014
P2, N=0, Completed, Sponsor: Herbert Irving Comprehensive Cancer Center
Active, not recruiting --> Completed Active, not recruiting --> Completed
- | Mylotarg (gemtuzumab ozogamicin) / UCB, PDL, Pfizer
Trial completion, Metastases: Gemtuzumab Ozogamicin, Fludarabine, and Total-body Irradiation Followed by Peripheral Stem Cell or Bone Marrow Transplantation in Treating Patients With Advanced Acute Myeloid Leukemia or Myelodysplastic Syndrome (clinicaltrials.gov) - Feb 19, 2014
P2, N=0, Completed, Sponsor: Fred Hutchinson Cancer Research Center
Active, not recruiting --> Completed Active, not recruiting --> Completed
- | busulfan / Generic mfg.
Trial completion: Busulfan in Treating Children and Adolescents With Refractory CNS Cancer (clinicaltrials.gov) - Feb 19, 2014
P1, N=28, Completed, Sponsor: Pediatric Brain Tumor Consortium
Active, not recruiting --> Completed No longer recruiting --> Completed
- | cyclophosphamide / Generic mfg.
Trial completion, Pre-transplantation: Cyclophosphamide Plus Bone Marrow Transplantation in Treating Patients With Hematologic Cancer (clinicaltrials.gov) - Feb 19, 2014
P1, N=0, Completed, Sponsor: Sidney Kimmel Comprehensive Cancer Center
No longer recruiting --> Completed Active, not recruiting --> Completed
- | topotecan / Generic mfg.
Trial completion: Topotecan Hydrochloride in Treating Children With Meningeal Cancer That Has Not Responded to Previous Treatment (clinicaltrials.gov) - Feb 19, 2014
P2, N=77, Completed, Sponsor: National Cancer Institute (NCI)
Active, not recruiting --> Completed Recruiting --> Completed
- | cyclophosphamide / Generic mfg.
Trial completion: Bone Marrow Transplantation in Treating Patients With Hematologic Cancer (clinicaltrials.gov) - Feb 19, 2014
P2, N=0, Completed, Sponsor: Fred Hutchinson Cancer Research Center
Recruiting --> Completed Active, not recruiting --> Completed
- | Proleukin (aldesleukin) / Merck (MSD), Novartis, Iovance Biotherap, Neupogen (filgrastim) / Kyowa Kirin, Amgen
Trial completion: Chemotherapy Followed by Donor White Blood Cells Plus Interleukin-2 in Treating Patients With Acute Myeloid or Lymphocytic Leukemia (clinicaltrials.gov) - Feb 19, 2014
P1/2, N=0, Completed, Sponsor: Fred Hutchinson Cancer Research Center
Active, not recruiting --> Completed Active, not recruiting --> Completed
- | topotecan / Generic mfg., carboplatin / Generic mfg., fludarabine IV / Generic mfg.
Trial completion, Metastases: Fludarabine, Carboplatin, and Topotecan in Treating Patients With Relapsed/Refractory Acute Leukemia or Advanced Myelodysplastic Syndrome (clinicaltrials.gov) - Feb 19, 2014
P1, N=31, Completed, Sponsor: Case Comprehensive Cancer Center
Active, not recruiting --> Completed Active, not recruiting --> Completed
- | Trial completion: Chemotherapy, Radiation Therapy, and Peripheral Stem Cell Transplantation in Treating Patients With Hematologic Cancer (clinicaltrials.gov) - Feb 19, 2014
P1, N=7, Completed, Sponsor: M.D. Anderson Cancer Center
Active, not recruiting --> Completed Active, not recruiting --> Completed
- | Neupogen (filgrastim) / Kyowa Kirin, Amgen, peripheral blood stem cell transplantation / National Cancer Institute
Trial completion, Post-transplantation: Stem Cell Transplantation in Treating Patients With Hematologic Cancer (clinicaltrials.gov) - Feb 19, 2014
P1, N=0, Completed, Sponsor: Northwestern University
Active, not recruiting --> Completed Not yet recruiting --> Completed
- | Neupogen (filgrastim) / Kyowa Kirin, Amgen, peripheral blood stem cell transplantation / National Cancer Institute
Trial completion: Bone Marrow and Peripheral Stem Cell Transplantation in Treating Patients With Hematologic Cancer (clinicaltrials.gov) - Feb 19, 2014
P1, N=0, Completed, Sponsor: Northwestern University
Not yet recruiting --> Completed Not yet recruiting --> Completed
- | captopril / Generic mfg.
Trial completion: Captopril in Treating Patients Undergoing Bone Marrow or Stem Cell Transplantation (clinicaltrials.gov) - Feb 19, 2014
P3, N=35, Completed, Sponsor: Northwestern University
Not yet recruiting --> Completed Active, not recruiting --> Completed
- | Neupogen (filgrastim) / Kyowa Kirin, Amgen
Trial completion: Umbilical Cord Blood Transplantation in Treating Patients With Hematologic Cancer or Nonmalignant Hematologic Disease (clinicaltrials.gov) - Feb 19, 2014
P2, N=390, Completed, Sponsor: Fred Hutchinson Cancer Research Center
Active, not recruiting --> Completed Active, not recruiting --> Completed
- | fluconazole oral / Generic mfg., itraconazole / Generic mfg.
Trial completion: Itraconazole Compared With Fluconazole to Prevent Infections in Patients Undergoing Peripheral Stem Cell or Bone Marrow Transplantation (clinicaltrials.gov) - Feb 19, 2014
P3, N=578, Completed, Sponsor: Fred Hutchinson Cancer Research Center
Active, not recruiting --> Completed Active, not recruiting --> Completed