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44 Companies |
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74 Products |
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52 Mechanisms of Action |
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4 Trials |
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- Trial completion, Trial primary completion date: Studying DNA in Samples From Younger Patients With Down Syndrome and Acute Myeloid Leukemia Treated on COG-AAML0431 Clinical Trial (clinicaltrials.gov) - May 19, 2016
P=N/A, N=10, Completed, Sponsor: Children's Oncology Group
Active, not recruiting --> Completed | Trial primary completion date: Jan 2100 --> May 2016
- | Biomarker, Trial completion, Trial primary completion date: Role of Biomarkers in Disease Progression in Samples From Patients With Acute Myeloid Leukemia (clinicaltrials.gov) - May 19, 2016
P=N/A, N=20, Completed, Sponsor: Children's Oncology Group
Active, not recruiting --> Completed | Trial primary completion date: Jan 2100 --> May 2016 Active, not recruiting --> Completed | Trial primary completion date: Jan 2100 --> May 2016
- ||| Trial completion, Trial primary completion date: Study to Predict Risk of Relapse in Bone Marrow Cell Samples From Younger Patients With Acute Myeloid Leukemia (clinicaltrials.gov) - May 19, 2016
P=N/A, N=98, Completed, Sponsor: Children's Oncology Group
Active, not recruiting --> Completed | Trial primary completion date: Jan 2100 --> May 2016 Active, not recruiting --> Completed | Trial primary completion date: Jan 2100 --> May 2016
- | Trial completion, Trial primary completion date: Study of Proteins in Promoting Chemotherapy Resistance in Samples From Patients With Acute Myeloid Leukemia (clinicaltrials.gov) - May 19, 2016
P=N/A, N=40, Completed, Sponsor: Children's Oncology Group
Active, not recruiting --> Completed | Trial primary completion date: Jan 2100 --> May 2016 Active, not recruiting --> Completed | Trial primary completion date: Jan 2100 --> May 2016
- ||| Biomarker, Trial completion, Trial primary completion date: Biomarkers in Predicting Response to Treatment in Bone Marrow Samples From Young Patients With Acute Myeloid Leukemia (clinicaltrials.gov) - May 19, 2016
P=N/A, N=97, Completed, Sponsor: Children's Oncology Group
Active, not recruiting --> Completed | Trial primary completion date: Jan 2100 --> May 2016 Active, not recruiting --> Completed | Trial primary completion date: Jan 2100 --> May 2016
- Biomarker, Trial completion, Trial primary completion date: Biomarkers in Samples of Bone Marrow From Patients With Acute Myeloid Leukemia (clinicaltrials.gov) - May 19, 2016
P=N/A, N=9, Completed, Sponsor: Children's Oncology Group
Active, not recruiting --> Completed | Trial primary completion date: Jan 2100 --> May 2016 Active, not recruiting --> Completed | Trial primary completion date: Jan 2100 --> Jan 2015
- ||| Biomarker, Trial completion, Trial initiation date, Trial primary completion date: Prognostic Biomarkers in Samples From Young Patients With Acute Myeloid Leukemia (clinicaltrials.gov) - May 19, 2016
P=N/A, N=150, Completed, Sponsor: Children's Oncology Group
Active, not recruiting --> Completed | Trial primary completion date: Jan 2100 --> Jan 2015 Active, not recruiting --> Completed | Initiation date: Nov 2010 --> May 2010 | Trial primary completion date: Jan 2100 --> May 2016
- | Biomarker, Trial completion, Trial primary completion date: RNA Biomarkers in Tissue Samples From Infants With Acute Myeloid Leukemia (clinicaltrials.gov) - May 19, 2016
P=N/A, N=20, Completed, Sponsor: Children's Oncology Group
Active, not recruiting --> Completed | Initiation date: Nov 2010 --> May 2010 | Trial primary completion date: Jan 2100 --> May 2016 Active, not recruiting --> Completed | Trial primary completion date: Jan 2100 --> May 2016
- | lestaurtinib (CEP-701) / Teva, Kyowa Kirin
Trial completion, Trial primary completion date: Lestaurtinib With or Without Chemotherapy Agents in Samples From Young Patients With Leukemia (clinicaltrials.gov) - May 19, 2016
P=N/A, N=18, Completed, Sponsor: Children's Oncology Group
Active, not recruiting --> Completed | Trial primary completion date: Jan 2100 --> May 2016 Recruiting --> Completed | Trial primary completion date: Jan 2100 --> May 2016
- | obatoclax (GX 15-070) / Teva
Trial completion, Trial primary completion date: Obatoclax Mesylate in Samples From Young Patients With Acute Myeloid Leukemia (clinicaltrials.gov) - May 19, 2016
P=N/A, N=50, Completed, Sponsor: Children's Oncology Group
Recruiting --> Completed | Trial primary completion date: Jan 2100 --> May 2016 Active, not recruiting --> Completed | Trial primary completion date: Jan 2100 --> May 2016
- | Trial completion, Trial initiation date, Trial primary completion date: Identification of de Novo Fanconi Anemia in Younger Patients With Newly Diagnosed Acute Myeloid Leukemia (clinicaltrials.gov) - May 19, 2016
P=N/A, N=20, Completed, Sponsor: Children's Oncology Group
Active, not recruiting --> Completed | Trial primary completion date: Jan 2100 --> May 2016 Recruiting --> Completed | Initiation date: Oct 2009 --> May 2009 | Trial primary completion date: Jan 2100 --> May 2016
- | Biomarker, Trial completion, Trial primary completion date: Biomarker Changes in Samples From Young Patients With Acute Myeloid Leukemia (clinicaltrials.gov) - May 19, 2016
P=N/A, N=15, Completed, Sponsor: Children's Oncology Group
Recruiting --> Completed | Initiation date: Oct 2009 --> May 2009 | Trial primary completion date: Jan 2100 --> May 2016 Active, not recruiting --> Completed | Trial primary completion date: Jan 2100 --> May 2016
- ||| Trial completion, Trial primary completion date: Blood and Tumor Tissue Samples From Young Patients With Acute Myeloid Leukemia (clinicaltrials.gov) - May 19, 2016
P=N/A, N=52, Completed, Sponsor: Children's Oncology Group
Active, not recruiting --> Completed | Trial primary completion date: Jan 2100 --> May 2016 Active, not recruiting --> Completed | Trial primary completion date: Jan 2100 --> May 2016
- ||| Mylotarg (gemtuzumab ozogamicin) / UCB, PDL, Pfizer
Biomarker, Trial completion, Trial primary completion date: Biomarkers in DNA Samples From Younger Patients With Newly Diagnosed Acute Myeloid Leukemia Receiving Gemtuzumab Ozogamicin (clinicaltrials.gov) - May 19, 2016
P=N/A, N=300, Completed, Sponsor: Children's Oncology Group
Active, not recruiting --> Completed | Trial primary completion date: Jan 2100 --> May 2016 Active, not recruiting --> Completed | Trial primary completion date: Jan 2100 --> May 2016
- ||| Biomarker, Trial completion, Trial primary completion date: Biomarkers in Samples From Young Patients With Acute Myeloid Leukemia (clinicaltrials.gov) - May 19, 2016
P=N/A, N=149, Completed, Sponsor: Children's Oncology Group
Active, not recruiting --> Completed | Trial primary completion date: Jan 2100 --> May 2016 Active, not recruiting --> Completed | Trial primary completion date: Jan 2100 --> May 2016
- ||| Biomarker, Trial completion, Trial primary completion date: Studying Biomarkers in Cell Samples From Young Patients With Acute Myeloid Leukemia (clinicaltrials.gov) - May 19, 2016
P=N/A, N=75, Completed, Sponsor: Children's Oncology Group
Active, not recruiting --> Completed | Trial primary completion date: Jan 2100 --> May 2016 Active, not recruiting --> Completed | Trial primary completion date: Jan 2100 --> May 2016
- ||| Biomarker, Trial completion, Trial primary completion date: Studying Biomarkers in Tissue Samples From Young Patients With Acute Myeloid Leukemia Previously Enrolled on Clinical Trial POG-9421 (clinicaltrials.gov) - May 19, 2016
P=N/A, N=90, Completed, Sponsor: Children's Oncology Group
Active, not recruiting --> Completed | Trial primary completion date: Jan 2100 --> May 2016 Active, not recruiting --> Completed | Trial primary completion date: Jan 2100 --> May 2016
- ||| Trial completion, Trial primary completion date: Studying DNA in Blood and Bone Marrow Samples From Younger Patients With Acute Myeloid Leukemia (clinicaltrials.gov) - May 19, 2016
P=N/A, N=2500, Completed, Sponsor: Children's Oncology Group
Active, not recruiting --> Completed | Trial primary completion date: Jan 2100 --> May 2016 Active, not recruiting --> Completed | Trial primary completion date: Jan 2100 --> May 2016
- Trial primary completion date: Immune Response After Stem Cell Transplant in HIV-Positive Patients With Hematologic Cancer (clinicaltrials.gov) - May 13, 2016
P2, N=10, Recruiting, Sponsor: Fred Hutchinson Cancer Research Center
Active, not recruiting --> Completed | Trial primary completion date: Jan 2100 --> May 2016 Trial primary completion date: Sep 2016 --> Mar 2017
- Thymoglobulin (anti-thymocyte globulin (rabbit)) / Sanofi
Trial completion: Fludarabine Phosphate, Busulfan, and Anti-Thymocyte Globulin Followed By Donor Peripheral Blood Stem Cell Transplant, Tacrolimus, and Methotrexate in Treating Patients With Myeloid Malignancies (clinicaltrials.gov) - May 6, 2016
P2, N=23, Completed, Sponsor: Fred Hutchinson Cancer Research Center
Trial primary completion date: Sep 2016 --> Mar 2017 Active, not recruiting --> Completed
- decitabine / Generic mfg.
Trial primary completion date: AR-42 and Decitabine in Treating Patients With Acute Myeloid Leukemia (clinicaltrials.gov) - Apr 7, 2016
P1, N=54, Active, not recruiting, Sponsor: Alison Walker
Active, not recruiting --> Completed Trial primary completion date: Dec 2015 --> Dec 2016
- dilanubicel (DVX101) / Deverra Therapeutics
Trial primary completion date: Expanded Cord Blood Cell Infusion Following Combination Chemotherapy in Younger Patients With Relapsed or Refractory Acute Myeloid Leukemia (clinicaltrials.gov) - Apr 1, 2016
P=N/A, N=15, Recruiting, Sponsor: Fred Hutchinson Cancer Research Center
Trial primary completion date: Dec 2015 --> Dec 2016 Trial primary completion date: May 2016 --> Dec 2016
- OXS-1550 / GT Biopharma
Enrollment closed: DT2219ARL for Relapsed or Refractory CD19 (+), CD 22 (+) B-Lineage Leukemia Or Lymphoma (clinicaltrials.gov) - Jan 25, 2016
P1, N=25, Active, not recruiting, Sponsor: Masonic Cancer Center, University of Minnesota
Trial primary completion date: May 2016 --> Dec 2016 Completed --> Active, not recruiting
- | NN1213 / Novo Nordisk
Trial completion: Traumeel (clinicaltrials.gov) - Jan 5, 2016
P=N/A, N=195, Completed, Sponsor: Children's Oncology Group
Completed --> Active, not recruiting Active, not recruiting --> Completed
- Trial completion, Enrollment change, Trial primary completion date: Donor Stem Cell Transplant or Bone Marrow Transplant in Treating Patients With Acute Myeloid Leukemia in Remission (clinicaltrials.gov) - Dec 31, 2015
P2, N=263, Completed, Sponsor: Asan Medical Center
Active, not recruiting --> Completed Recruiting --> Completed | N=200 --> 263 | Trial primary completion date: Dec 2013 --> Jul 2015
- Neupogen (filgrastim) / Kyowa Kirin, Amgen
Clinical: T-cell Depleted Bone Marrow and G-CSF Stimulated Peripheral Stem Cell Transplantation From Related Donors in Treating Patients With Leukemia, Lymphoblastic Lymphoma, Myelodysplastic Syndrome, or Aplastic Anemia (clinicaltrials.gov) - Dec 23, 2015
P2, N=31, Completed, Sponsor: Memorial Sloan Kettering Cancer Center
Recruiting --> Completed | N=200 --> 263 | Trial primary completion date: Dec 2013 --> Jul 2015 Trial primary completion date: Oct 2008 --> Jan 2004
- cyclophosphamide / Generic mfg., thiotepa / Generic mfg.
Trial primary completion date: Total-Body Irradiation and Chemotherapy Followed By Donor Bone Marrow Transplant in Treating Young Patients With Hematologic Cancer (clinicaltrials.gov) - Dec 23, 2015
P2, N=25, Completed, Sponsor: Memorial Sloan Kettering Cancer Center
Trial primary completion date: Oct 2008 --> Jan 2004 Trial primary completion date: Jun 2008 --> Jul 2006
- Thymoglobulin (anti-thymocyte globulin (rabbit)) / Sanofi
Clinical: Donor Umbilical Cord Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies (clinicaltrials.gov) - Dec 21, 2015
P2, N=14, Completed, Sponsor: Case Comprehensive Cancer Center
Trial primary completion date: Jun 2008 --> Jul 2006 Active, not recruiting --> Completed | N=47 --> 14 | Trial primary completion date: Sep 2015 --> Dec 2015
- | cyclophosphamide / Generic mfg., thiotepa / Generic mfg.
Trial completion: Total-Body Irradiation and Chemotherapy Followed By Donor Bone Marrow Transplant in Treating Young Patients With Hematologic Cancer (clinicaltrials.gov) - Dec 21, 2015
P2, N=25, Completed, Sponsor: Memorial Sloan Kettering Cancer Center
Active, not recruiting --> Completed | N=47 --> 14 | Trial primary completion date: Sep 2015 --> Dec 2015 Active, not recruiting --> Completed
- fludarabine IV / Generic mfg., busulfan / Generic mfg.
Trial primary completion date: Reduced-Intensity Busulfan and Fludarabine With or Without Antithymocyte Globulin Followed by Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer or Other Disease (clinicaltrials.gov) - Nov 26, 2015
P2, N=70, Active, not recruiting, Sponsor: UNC Lineberger Comprehensive Cancer Center
Active, not recruiting --> Completed Trial primary completion date: Dec 2015 --> Dec 2016
- fludarabine IV / Generic mfg., mycophenolate mofetil / Generic mfg.
Trial completion, Enrollment change, Trial primary completion date, Combination therapy, IO biomarker, Post-transplantation: Fludarabine and Total-Body Irradiation Followed By Donor Stem Cell Transplant and Cyclosporine and Mycophenolate Mofetil in Treating HIV-Positive Patients With or Without Cancer (clinicaltrials.gov) - Sep 1, 2015
P=N/A, N=5, Completed, Sponsor: Fred Hutchinson Cancer Research Center
Trial primary completion date: Dec 2015 --> Dec 2016 Recruiting --> Completed | N=20 --> 5 | Trial primary completion date: Dec 2015 --> Nov 2014
- fludarabine IV / Generic mfg., cyclophosphamide / Generic mfg.
Trial completion, Enrollment change, Trial primary completion date: Fludarabine, Cyclophosphamide, and Total-Body Irradiation in Treating Patients Who Are Undergoing a Donor Bone Marrow Transplant for Hematologic Cancer (clinicaltrials.gov) - Aug 24, 2015
P2, N=210, Completed, Sponsor: Sidney Kimmel Comprehensive Cancer Center
Recruiting --> Completed | N=20 --> 5 | Trial primary completion date: Dec 2015 --> Nov 2014 Active, not recruiting --> Completed | N=100 --> 210 | Trial primary completion date: Dec 2015 --> Jan 2015
- Trial primary completion date, HEOR: Massage Therapy Given by Caregiver in Treating Quality of Life of Young Patients Undergoing Treatment for Cancer (clinicaltrials.gov) - Aug 13, 2015
P=N/A, N=80, Active, not recruiting, Sponsor: Comprehensive Cancer Center of Wake Forest University
Active, not recruiting --> Completed | N=100 --> 210 | Trial primary completion date: Dec 2015 --> Jan 2015 Trial primary completion date: Oct 2011 --> Feb 2012
- busulfan / Generic mfg., etoposide IV / Generic mfg.
Trial completion, Enrollment change: Busulfan and Etoposide Followed by Peripheral Blood Stem Cell Transplant and Low-Dose Aldesleukin in Treating Patients With Acute Myeloid Leukemia (clinicaltrials.gov) - Aug 13, 2015
P2, N=62, Completed, Sponsor: Fred Hutchinson Cancer Research Center
Trial primary completion date: Oct 2011 --> Feb 2012 Active, not recruiting --> Completed | N=30 --> 62
- Trial completion, Post-transplantation: Cyclophosphamide for Prevention of Graft-Versus-Host Disease After Allogeneic Peripheral Blood Stem Cell Transplantation in Patients With Hematological Malignancies (clinicaltrials.gov) - Aug 12, 2015
P2, N=44, Completed, Sponsor: Fred Hutchinson Cancer Research Center
Active, not recruiting --> Completed | N=30 --> 62 Active, not recruiting --> Completed
- Neupogen (filgrastim) / Kyowa Kirin, Amgen
Trial completion, Enrollment change, Trial primary completion date: Donor Stem Cell Transplant in Treating Patients With Relapsed Hematologic Malignancies or Secondary Myelodysplasia Previously Treated With High-Dose Chemotherapy and Autologous Stem Cell Transplant (clinicaltrials.gov) - Jul 10, 2015
P2, N=6, Completed, Sponsor: Alliance for Clinical Trials in Oncology
Active, not recruiting --> Completed Active, not recruiting --> Completed | N=88 --> 6 | Trial primary completion date: Sep 2014 --> Dec 2011
- fludarabine IV / Generic mfg., cyclophosphamide / Generic mfg.
Trial completion, Enrollment change, Trial primary completion date: Chemotherapy and a Donor Natural Killer Cell Infusion in Treating Patients With Relapsed or Persistent Leukemia or Myelodysplastic Syndrome After a Donor Stem Cell Transplant (clinicaltrials.gov) - Jul 9, 2015
P2, N=12, Completed, Sponsor: Memorial Sloan Kettering Cancer Center
Active, not recruiting --> Completed | N=88 --> 6 | Trial primary completion date: Sep 2014 --> Dec 2011 Active, not recruiting --> Completed | N=30 --> 12 | Trial primary completion date: Dec 2015 --> Jul 2015
- Biomarker, Enrollment closed: Biomarkers in Samples of Bone Marrow From Patients With Acute Myeloid Leukemia (clinicaltrials.gov) - May 12, 2015
P=N/A, N=9, Active, not recruiting, Sponsor: Children's Oncology Group
Active, not recruiting --> Completed | N=30 --> 12 | Trial primary completion date: Dec 2015 --> Jul 2015 Not yet recruiting --> Active, not recruiting
- | Biomarker, Trial completion: Drug Biomarkers in Cell Samples From Patients With Acute Myeloid Leukemia (clinicaltrials.gov) - May 12, 2015
P=N/A, N=40, Completed, Sponsor: Children's Oncology Group
Not yet recruiting --> Active, not recruiting Active, not recruiting --> Completed
- Biomarker, Trial primary completion date: Biomarker Changes in Samples From Young Patients With Acute Myeloid Leukemia (clinicaltrials.gov) - May 8, 2015
P=N/A, N=15, Active, not recruiting, Sponsor: Children's Oncology Group
Active, not recruiting --> Completed Trial primary completion date: Jul 2010 --> Jan 2100
- || Trial primary completion date: Studying DNA in Blood and Bone Marrow Samples From Younger Patients With Acute Myeloid Leukemia (clinicaltrials.gov) - May 8, 2015
P=N/A, N=2500, Active, not recruiting, Sponsor: Children's Oncology Group
Trial primary completion date: Jul 2010 --> Jan 2100 Trial primary completion date: Jan 2010 --> Jan 2100
- || Trial primary completion date: Blood and Tumor Tissue Samples From Young Patients With Acute Myeloid Leukemia (clinicaltrials.gov) - May 7, 2015
P=N/A, N=52, Active, not recruiting, Sponsor: Children's Oncology Group
Trial primary completion date: Jan 2010 --> Jan 2100 Trial primary completion date: Oct 2010 --> Jan 2100
- || Mylotarg (gemtuzumab ozogamicin) / UCB, PDL, Pfizer
Biomarker, Trial primary completion date: Biomarkers in DNA Samples From Younger Patients With Newly Diagnosed Acute Myeloid Leukemia Receiving Gemtuzumab Ozogamicin (clinicaltrials.gov) - May 7, 2015
P=N/A, N=300, Active, not recruiting, Sponsor: Children's Oncology Group
Trial primary completion date: Oct 2010 --> Jan 2100 Trial primary completion date: Dec 2011 --> Jan 2100
- Biomarker, Enrollment open, Trial primary completion date, IO biomarker: Studying Biomarkers in Samples From Younger Patients With Acute Myeloid Leukemia (clinicaltrials.gov) - May 7, 2015
P=N/A, N=20, Recruiting, Sponsor: Children's Oncology Group
Trial primary completion date: Dec 2011 --> Jan 2100 Active, not recruiting --> Recruiting | Trial primary completion date: Sep 2012 --> Jan 2100
- || Biomarker, Trial primary completion date: Prognostic Biomarkers in Samples From Young Patients With Acute Myeloid Leukemia (clinicaltrials.gov) - May 6, 2015
P=N/A, N=150, Active, not recruiting, Sponsor: Children's Oncology Group
Active, not recruiting --> Recruiting | Trial primary completion date: Sep 2012 --> Jan 2100 Trial primary completion date: Feb 2011 --> Jan 2100
- || Biomarker, Trial primary completion date: Studying Biomarkers in Cell Samples From Young Patients With Acute Myeloid Leukemia (clinicaltrials.gov) - May 6, 2015
P=N/A, N=75, Active, not recruiting, Sponsor: Children's Oncology Group
Trial primary completion date: Feb 2011 --> Jan 2100 Trial primary completion date: Jan 2021 --> Jan 2100
- || Biomarker, Trial initiation date, Trial primary completion date: Biomarkers in Samples From Young Patients With Acute Myeloid Leukemia (clinicaltrials.gov) - May 6, 2015
P=N/A, N=149, Active, not recruiting, Sponsor: Children's Oncology Group
Trial primary completion date: Jan 2021 --> Jan 2100 Initiation date: Sep 2009 --> Feb 2013 | Trial primary completion date: Jun 2011 --> Jan 2100
- ||| Enrollment open, Trial primary completion date: Studying Genes in Samples From Younger Patients With Acute Megakaryoblastic Leukemia (clinicaltrials.gov) - May 6, 2015
P=N/A, N=100, Recruiting, Sponsor: Children's Oncology Group
Initiation date: Sep 2009 --> Feb 2013 | Trial primary completion date: Jun 2011 --> Jan 2100 Active, not recruiting --> Recruiting | Trial primary completion date: Sep 2012 --> Jan 2100
- Biomarker, Enrollment closed: Biomarkers in Samples From Patients With Down Syndrome and Acute Megakaryoblastic Leukemia (clinicaltrials.gov) - May 6, 2015
P=N/A, N=10, Active, not recruiting, Sponsor: Children's Oncology Group
Active, not recruiting --> Recruiting | Trial primary completion date: Sep 2012 --> Jan 2100 Completed --> Active, not recruiting
- | Biomarker, Trial completion, Trial initiation date: Biomarkers in Patients With Acute Myeloid Leukemia (clinicaltrials.gov) - May 6, 2015
P=N/A, N=18, Completed, Sponsor: Children's Oncology Group
Completed --> Active, not recruiting Active, not recruiting --> Completed | Initiation date: Sep 2009 --> Feb 2009