Acute Myeloid Leukemia, Adult
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 176 Companies   232 Products   232 Products   108 Mechanisms of Action   9 Trials   1978 News 


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  • ||||||||||  Phase classification, Trial completion date, Trial primary completion date:  Red Cell Transfusion Goals in Patients With Acute Leukemias (clinicaltrials.gov) -  Apr 19, 2018   
    P=N/A,  N=90, Active, not recruiting, 
    Suspended --> Recruiting Phase classification: P1 --> P=N/A | Trial completion date: Jun 2017 --> Dec 2019 | Trial primary completion date: Apr 2017 --> Dec 2018
  • ||||||||||  Mekinist (trametinib) / Novartis, BeiGene, uprosertib (LAE003) / Laekna Therap
    Trial termination, Combination therapy:  Trametinib and Akt Inhibitor GSK2141795 in Treating Patients With Acute Myeloid Leukemia (clinicaltrials.gov) -  Apr 6, 2018   
    P2,  N=24, Terminated, 
    Phase classification: P=N/A --> P | N=60 --> 8 | Trial completion date: Mar 2016 --> Mar 2018 | Trial primary completion date: Mar 2016 --> Mar 2018 Active, not recruiting --> Terminated; Lack of efficacy.
  • ||||||||||  Xpovio (selinexor) / Karyopharm
    Trial completion, Enrollment change, Trial completion date, Combination therapy:  Selinexor and Chemotherapy in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia (clinicaltrials.gov) -  Apr 4, 2018   
    P1,  N=23, Completed, 
    Active, not recruiting --> Completed | Trial completion date: Dec 2018 --> Oct 2017 | Trial primary completion date: Aug 2018 --> Oct 2017 Recruiting --> Completed | N=60 --> 23 | Trial completion date: Dec 2019 --> Mar 2018
  • ||||||||||  Enrollment change, Trial completion date, Trial termination, Trial primary completion date:  Donor Stem Cell Transplant in Treating Patients With High Risk Acute Myeloid Leukemia (clinicaltrials.gov) -  Mar 31, 2018   
    P1,  N=10, Terminated, 
    Recruiting --> Completed | N=60 --> 23 | Trial completion date: Dec 2019 --> Mar 2018 N=35 --> 10 | Trial completion date: Mar 2019 --> Aug 2017 | Recruiting --> Terminated | Trial primary completion date: Mar 2018 --> Jul 2017; Insufficient Accrual
  • ||||||||||  Erwinase (erwinia L-asparaginase) / Jazz, Ohara Pharma
    Trial completion, Trial completion date:  1336GCC: Study of Erwinaze for Treatment of Acute Myeloid Leukemia (AML) (clinicaltrials.gov) -  Mar 12, 2018   
    P1,  N=5, Completed, 
    Recruiting --> Withdrawn Active, not recruiting --> Completed | Trial completion date: Dec 2020 --> Sep 2017
  • ||||||||||  mitoxantrone / Generic mfg., gemcitabine / Generic mfg.
    Trial termination:  Gemcitabine and Mitoxantrone in Treating Patients With Relapsed Acute Myeloid Leukemia (clinicaltrials.gov) -  Feb 22, 2018   
    P2,  N=24, Terminated, 
    Completed --> Terminated; If </= 5 of the initial 18 patients had a CR, the study would be stopped. Only 5 patients (21%) of 24 enrolled patients had a CR so the study was terminated.
  • ||||||||||  cyclophosphamide / Generic mfg.
    Trial completion, Post-transplantation:  Post-transplantation Cyclophosphamide as GVHD Prophylaxis After HSCT (clinicaltrials.gov) -  Jan 16, 2018   
    P2,  N=200, Completed, 
    Active, not recruiting --> Completed | Trial primary completion date: Dec 2017 --> Jun 2014 Active, not recruiting --> Completed
  • ||||||||||  Trial completion, Trial primary completion date:  A Feasibility Study of Prophylactic White Blood Cell Transfusions (clinicaltrials.gov) -  Jan 12, 2018   
    P2,  N=45, Completed, 
    Active, not recruiting --> Completed | Trial primary completion date: Dec 2017 --> Aug 2016 Active, not recruiting --> Completed | Trial primary completion date: Sep 2018 --> Nov 2016
  • ||||||||||  vadastuximab talirine (SGN-CD33A) / Pfizer
    Trial completion:  A Safety Study of SGN-CD33A in AML Patients (clinicaltrials.gov) -  Jan 5, 2018   
    P1,  N=195, Completed, 
    Phase classification: P1/2 --> P1b/2 | Trial primary completion date: Jul 2011 --> Feb 2012 Active, not recruiting --> Completed
  • ||||||||||  Xpovio (selinexor) / Karyopharm
    Trial completion, Trial primary completion date, IO biomarker:  Decitabine and Selinexor in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia (clinicaltrials.gov) -  Dec 8, 2017   
    P1,  N=25, Completed, 
    Active, not recruiting --> Completed | Trial primary completion date: Jun 2018 --> Jun 2017 Active, not recruiting --> Completed | Trial primary completion date: Jul 2017 --> Nov 2016