- |||||||||| Phase classification, Trial completion date, Trial primary completion date: Red Cell Transfusion Goals in Patients With Acute Leukemias (clinicaltrials.gov) - Apr 19, 2018
P=N/A, N=90, Active, not recruiting, Suspended --> Recruiting Phase classification: P1 --> P=N/A | Trial completion date: Jun 2017 --> Dec 2019 | Trial primary completion date: Apr 2017 --> Dec 2018
- |||||||||| cytarabine / Generic mfg., decitabine / Generic mfg.
Trial completion, Enrollment change, Metastases: Decitabine and Cytarabine in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia, High Risk Myelodysplastic Syndrome, or Myeloproliferative Neoplasm (clinicaltrials.gov) - Apr 13, 2018 P=N/A, N=12, Completed, Phase classification: P1 --> P=N/A | Trial completion date: Jun 2017 --> Dec 2019 | Trial primary completion date: Apr 2017 --> Dec 2018 Active, not recruiting --> Completed | N=30 --> 12
- |||||||||| Mekinist (trametinib) / Novartis, BeiGene, uprosertib (LAE003) / Laekna Therap
Trial termination, Combination therapy: Trametinib and Akt Inhibitor GSK2141795 in Treating Patients With Acute Myeloid Leukemia (clinicaltrials.gov) - Apr 6, 2018 P2, N=24, Terminated, Phase classification: P=N/A --> P | N=60 --> 8 | Trial completion date: Mar 2016 --> Mar 2018 | Trial primary completion date: Mar 2016 --> Mar 2018 Active, not recruiting --> Terminated; Lack of efficacy.
- |||||||||| Xpovio (selinexor) / Karyopharm
Trial completion, Enrollment change, Trial completion date, Combination therapy: Selinexor and Chemotherapy in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia (clinicaltrials.gov) - Apr 4, 2018 P1, N=23, Completed, Active, not recruiting --> Completed | Trial completion date: Dec 2018 --> Oct 2017 | Trial primary completion date: Aug 2018 --> Oct 2017 Recruiting --> Completed | N=60 --> 23 | Trial completion date: Dec 2019 --> Mar 2018
- |||||||||| Enrollment change, Trial completion date, Trial termination, Trial primary completion date: Donor Stem Cell Transplant in Treating Patients With High Risk Acute Myeloid Leukemia (clinicaltrials.gov) - Mar 31, 2018
P1, N=10, Terminated, Recruiting --> Completed | N=60 --> 23 | Trial completion date: Dec 2019 --> Mar 2018 N=35 --> 10 | Trial completion date: Mar 2019 --> Aug 2017 | Recruiting --> Terminated | Trial primary completion date: Mar 2018 --> Jul 2017; Insufficient Accrual
- |||||||||| Trial completion, Trial primary completion date: A Feasibility Study of Prophylactic White Blood Cell Transfusions (clinicaltrials.gov) - Jan 12, 2018
P2, N=45, Completed, Active, not recruiting --> Completed | Trial primary completion date: Dec 2017 --> Aug 2016 Active, not recruiting --> Completed | Trial primary completion date: Sep 2018 --> Nov 2016
- |||||||||| vadastuximab talirine (SGN-CD33A) / Pfizer
Trial completion: A Safety Study of SGN-CD33A in AML Patients (clinicaltrials.gov) - Jan 5, 2018 P1, N=195, Completed, Phase classification: P1/2 --> P1b/2 | Trial primary completion date: Jul 2011 --> Feb 2012 Active, not recruiting --> Completed
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