Acute Myeloblastic Leukemia Without Maturation MOAs

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Phase N/A 1 2 3 4 Products	0	2	4	6	8	10	12	14	16	18	20



Purinergic receptor P1 agon




IL-12 inhib




AKT inhib




CD52 inhib




c-KIT inhib




DNA synthesis inhib




HDAC2 inhib




GCR agon




PDGFR inhib




VEGF inhib




c-KIT inhib




AKT inhib




IL-6 inhib




mTOR inhib




Calcineurin inhib




IL-2 stim




IMPDH inhib




Immunosuppressant




PI3K inhib




TIE-2 antag




Angiopoietin 2 inhib




Apoptosis stim




BRAF inhib




Bone morphogenetic protein receptor type II mod




CDK6 inhib




CXCL12 inhib




Cytomegalovirus replication inhib




DGAT-1 inhib




Dihydrofolic acid reductase inhib




Farnesyl transferase inhib




GM-CSF agon




GM-CSF agon




HIF-1 inhib




Histamine release inhib




IFNα 2b stim




IL-10 stim




IL-12 inhib




IL-1β inhib




IL-6 inhib




Integrin inhib




JNK inhib




KIF11 inhib




MAPK inhib




PARP2 inhib




PKC inhib




Proteasome inhib




RAF kinase inhib




RAS inhib




Retinoid X receptor mod




STAT3 inhib



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