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31 Companies |
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24 Products |
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24 Products |
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24 Mechanisms of Action |
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0 Trials |
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748 News |
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- Ventavis (iloprost) / Bayer, J&J, University of Copenhagen
Enrollment change: Inhaled Iloprost as an Adjunct to Inhaled Nitric Oxide in Pediatric Critical Care Patients (clinicaltrials.gov) - Mar 6, 2013
P1/2, N=0, Withdrawn, Sponsor: Seattle Children's Hospital
N=40 --> 0
- Enrollment open: Evaluation of the Lung Recruitment and End-expiratory Lung Collapse in Acute Respiratory Distress Syndrome (ARDS) (clinicaltrials.gov) - Mar 5, 2013
P=N/A, N=30, Recruiting, Sponsor: Policlinico Hospital
N=40 --> 0 Not yet recruiting --> Recruiting
- Enrollment closed: Feasibility of Mid-frequency Ventilation in Newborns With RDS: Randomized Crossover Pilot Trial (clinicaltrials.gov) - Feb 28, 2013
P1/2, N=20, Active, not recruiting, Sponsor: University of Alabama at Birmingham
Not yet recruiting --> Recruiting Recruiting --> Active, not recruiting
- Trial completion: PED-ALIEN: Incidence of Acute Lung Injury in Children (clinicaltrials.gov) - Feb 22, 2013
P=N/A, N=200, Completed, Sponsor: Dr. Negrin University Hospital
Recruiting --> Active, not recruiting Enrolling by invitation --> Completed
- Trial termination: VVCCO2R: Venovenous CO2 Removal (VVCO2R) in Patients With COPD and Acute Respiratory Failure (clinicaltrials.gov) - Feb 10, 2013
P1/2, N=2, Terminated, Sponsor: The University of Texas, Galveston
Enrolling by invitation --> Completed Suspended --> Terminated; due to loss of key personnel due to illness and sabbatical of thePI
- Enrollment open: RV STAR: Echocardiography Predictive of the Inefficacy and/or of the Unsafeness of Recruitment Maneuvers in Patients With Acute Respiratory Distress Syndrome. (clinicaltrials.gov) - Feb 7, 2013
P=N/A, N=50, Recruiting, Sponsor: Centre Hospitalier Universitaire de Besancon
Suspended --> Terminated; due to loss of key personnel due to illness and sabbatical of thePI Not yet recruiting --> Recruiting
- | dexmedetomidine / Generic mfg.
Trial completion: Efficacy and Safety of Dexmedetomidine During Non-Invasive Positive Pressure Ventilation (clinicaltrials.gov) - Feb 7, 2013
P2, N=36, Completed, Sponsor: Tufts Medical Center
Not yet recruiting --> Recruiting Recruiting --> Completed
- Enrollment open: ViPS: Variable Pressure Support Trial (clinicaltrials.gov) - Feb 6, 2013
P=N/A, N=228, Recruiting, Sponsor: Dresden University of Technology
Recruiting --> Completed Not yet recruiting --> Recruiting
- ||||| New P2 trial: LIPS-B: Lung Injury Prevention Study With Budesonide and Beta (clinicaltrials.gov) - Feb 3, 2013
P2, N=60, Recruiting, Sponsor: Mayo Clinic
- Trial initiation date, Intubation: Observational Study Evaluating the Use of Intellivent (clinicaltrials.gov) - Jan 30, 2013
P=N/A, N=100, Recruiting, Sponsor: Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Not yet recruiting --> Recruiting Initiation date: Jan 2011 --> Jan 2013
- Trial completion: Weaning Using Noninvasive Positive Pressure Ventilation by Means of Helmet in Patients With Acute Respiratory Failure (clinicaltrials.gov) - Jan 29, 2013
P=N/A, N=250, Completed, Sponsor: University of Padova
Initiation date: Jan 2011 --> Jan 2013 Recruiting --> Completed
- New P1 trial: START: Human Mesenchymal Stem Cells For Acute Respiratory Distress Syndrome (clinicaltrials.gov) - Jan 23, 2013
P1, N=9, Recruiting, Sponsor: Michael A. Matthay
- || GSK1995057 / GSK
Enrollment change: Safety Study of GSK1995057 Given as Single and Repeat Intravenous Doses in Healthy Subjects. (clinicaltrials.gov) - Jan 16, 2013
P1, N=56, Completed, Sponsor: GlaxoSmithKline
Recruiting --> Completed N=78 --> 56
- ||| GSK1995057 / GSK
Trial completion: Safety Study of GSK1995057 Given as Single and Repeat Intravenous Doses in Healthy Subjects. (clinicaltrials.gov) - Jan 16, 2013
P1, N=56, Completed, Sponsor: GlaxoSmithKline
N=78 --> 56 Recruiting --> Completed
- dexmedetomidine / Generic mfg.
Clinical: Testing the Feasibility of Patient Controlled Sedation for Ventilated ICU Patients (clinicaltrials.gov) - Jan 13, 2013
P1/2, N=40, Recruiting, Sponsor: University of Minnesota - Clinical and Translational Science Institute
Recruiting --> Completed Initiation date: Jul 2012 --> Mar 2013
- Enrollment closed: Long-Term Results in Mechanically Ventilated Individuals With Acute Lung Injury/Acute Respiratory Distress Syndrome (clinicaltrials.gov) - Jan 13, 2013
P=N/A, N=520, Active, not recruiting, Sponsor: National Heart, Lung, and Blood Institute (NHLBI)
Initiation date: Jul 2012 --> Mar 2013 Recruiting --> Active, not recruiting
- New P1 trial, Surgery: Low Tidal Volume and EVLWI During OLV (clinicaltrials.gov) - Jan 6, 2013
P1, N=39, Completed, Sponsor: Dammam University
- Enrollment change: PET Imaging in Patients at Risk for Acute Lung Injury (clinicaltrials.gov) - Jan 2, 2013
P=N/A, N=5, Completed, Sponsor: Washington University School of Medicine
Recruiting --> Active, not recruiting N=10 --> 5
- Trial completion: PET Imaging in Patients at Risk for Acute Lung Injury (clinicaltrials.gov) - Jan 2, 2013
P=N/A, N=5, Completed, Sponsor: Washington University School of Medicine
N=10 --> 5 Recruiting --> Completed
- Trial completion: Interobserver Variation in Applying a Radiographic Definition for Acute Respiratory Distress Syndrome (ARDS) (clinicaltrials.gov) - Dec 19, 2012
P=N/A, N=286, Completed, Sponsor: Society of Critical Care Medicine, China
Recruiting --> Completed Recruiting --> Completed
- Enrollment open: Improved Accessibility of EmONC Services for Maternal and Newborn Health: a Community Based Project (clinicaltrials.gov) - Dec 18, 2012
P=N/A, N=6000, Recruiting, Sponsor: Aga Khan University
Recruiting --> Completed Not yet recruiting --> Recruiting
- Trial completion: Post-Hospital Case Management to Improve Clinical Outcomes in Individuals Requiring Mechanical Ventilation (clinicaltrials.gov) - Dec 17, 2012
P=N/A, N=600, Completed, Sponsor: University of Washington
Not yet recruiting --> Recruiting Active, not recruiting --> Completed
- Trial completion, Surgery: INFLACOR - Clinical and Genetic Predictors of Inflammation Related Complications After Heart Surgery (clinicaltrials.gov) - Dec 13, 2012
P4, N=525, Completed, Sponsor: Medical University of Gdansk
Active, not recruiting --> Completed Active, not recruiting --> Completed
- rocuronium / Generic mfg.
New P4 trial, Intubation: Premedication for Non-Emergency Endotracheal Intubation In the NICU (clinicaltrials.gov) - Dec 11, 2012
P4, N=32, Enrolling by invitation, Sponsor: Martin Espinosa, MD
- Trial withdrawal: The Interaction Between Severe Acute Respiratory Distress Syndrome Viral Proteins and Monocytes (clinicaltrials.gov) - Dec 5, 2012
P=N/A, N=0, Withdrawn, Sponsor: National Taiwan University Hospital
Active, not recruiting --> Completed Recruiting --> Withdrawn
- | New P4 trial: Comparison of Effectiveness of Nasal CPAP and Nasal IMV in Early Rescue Surfactant Treatment in Preterm Infants (clinicaltrials.gov) - Dec 2, 2012
P4, N=200, Completed, Sponsor: Mehmet Yekta
- Enrollment closed: Top-cuff: Prevention Inhalation of Bacterial by Using Endotracheal Tube Balloon Polyvinyl Chloride or Polyurethane (clinicaltrials.gov) - Nov 28, 2012
P=N/A, N=600, Active, not recruiting, Sponsor: Assistance Publique - H
Recruiting --> Withdrawn Recruiting --> Active, not recruiting
- | dexamethasone injection / Generic mfg.
New P4 trial: DEXA-ARDS: Efficacy Study of Dexamethasone to Treat the Acute Respiratory Distress Syndrome (clinicaltrials.gov) - Nov 20, 2012
P4, N=314, Not yet recruiting, Sponsor: Dr. Negrin University Hospital
- Trial termination: The Effect of Intravenous Lipids on Lung Function in Acute Respiratory Distress Syndrome (ARDS) (clinicaltrials.gov) - Nov 18, 2012
P2, N=14, Terminated, Sponsor: Methodist Research Institute, Indianapolis
Recruiting --> Active, not recruiting Recruiting --> Terminated; Unable to secure product from international source, low recruitment rate.
- Enrollment change: The Use of Palliative Non Invasive Ventilation in Acute Respiratory Failure. OVNI Study. (clinicaltrials.gov) - Nov 18, 2012
P=N/A, N=1450, Completed, Sponsor: Assistance Publique - H
Recruiting --> Terminated; Unable to secure product from international source, low recruitment rate. N=1000 --> 1450
- Enrollment change: The Effect of Intravenous Lipids on Lung Function in Acute Respiratory Distress Syndrome (ARDS) (clinicaltrials.gov) - Nov 18, 2012
P2, N=14, Terminated, Sponsor: Methodist Research Institute, Indianapolis
N=1000 --> 1450 N=50 --> 14
- Enrollment open: Open Lung Ventilation in ARDS: The PHARLAP Trial (clinicaltrials.gov) - Nov 18, 2012
P=N/A, N=340, Recruiting, Sponsor: Australian and New Zealand Intensive Care Research Centre
N=50 --> 14 Not yet recruiting --> Recruiting
- Trial completion: The Use of Palliative Non Invasive Ventilation in Acute Respiratory Failure. OVNI Study. (clinicaltrials.gov) - Nov 18, 2012
P=N/A, N=1450, Completed, Sponsor: Assistance Publique - H
Not yet recruiting --> Recruiting Recruiting --> Completed
- Enrollment open: Variable Ventilation During Acute Respiratory Failure (clinicaltrials.gov) - Nov 11, 2012
P1, N=16, Recruiting, Sponsor: Boston Medical Center
Recruiting --> Completed Not yet recruiting --> Recruiting
- |||| Enrollment open, IO biomarker: The Safety, Tolerability, PK and PD of GSK2586881 in Patients With Acute Lung Injury (clinicaltrials.gov) - Nov 7, 2012
P2, N=65, Recruiting, Sponsor: GlaxoSmithKline
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- Clinical: Weaning of Nasal Continuous Positive Airway Pressure (CPAP) in Premature Infants (clinicaltrials.gov) - Nov 4, 2012
P=N/A, N=300, Recruiting, Sponsor: Aarhus University Hospital
- Enrollment closed: ARDSnet Protocol vs. Open Lung Approach in ARDS (clinicaltrials.gov) - Nov 4, 2012
P=N/A, N=224, Active, not recruiting, Sponsor: Massachusetts General Hospital
Not yet recruiting --> Recruiting Recruiting --> Active, not recruiting
- | New P1 trial: Safety Study of Inhaled Saline in Acute Lung Injury (clinicaltrials.gov) - Oct 23, 2012
P1, N=15, Recruiting, Sponsor: Mayo Clinic
- Enrollment change: Changes in Refractory Acute Respiratory Distress Syndrome (ARDS) Patients Under High Frequency Oscillation-ventilation (clinicaltrials.gov) - Oct 22, 2012
P=N/A, N=23, Completed, Sponsor: Centre Hospitalier Felix Guyon
Recruiting --> Active, not recruiting N=50 --> 23
- || Neupogen (filgrastim) / Kyowa Kirin, Amgen
New P2/3 trial: HBP-Neupogen: Heparin Binding Protein in Patients With Acute Respiratory Failure Treated With GCSF (Filgrastim) (clinicaltrials.gov) - Oct 22, 2012
P2/3, N=59, Completed, Sponsor: Helsinki University Central Hospital
- Trial completion: Changes in Refractory Acute Respiratory Distress Syndrome (ARDS) Patients Under High Frequency Oscillation-ventilation (clinicaltrials.gov) - Oct 22, 2012
P=N/A, N=23, Completed, Sponsor: Centre Hospitalier Felix Guyon
N=50 --> 23 Recruiting --> Completed
- Trial initiation date: Mechanical Ventilation With Neurally-Adjusted Ventilatory Assist in Patients With ARDS (clinicaltrials.gov) - Oct 21, 2012
P=N/A, N=20, Recruiting, Sponsor: University of Sao Paulo General Hospital
Recruiting --> Completed Initiation date: Mar 2012 --> Oct 2012
- Enrollment open: Mechanical Ventilation With Neurally-Adjusted Ventilatory Assist in Patients With ARDS (clinicaltrials.gov) - Oct 21, 2012
P=N/A, N=20, Recruiting, Sponsor: University of Sao Paulo General Hospital
Initiation date: Mar 2012 --> Oct 2012 Not yet recruiting --> Recruiting
- || Curosurf (poractant alfa) / Chiesi
New P3 trial: A Multi-center Trial to Determine if Curosurf (clinicaltrials.gov) - Oct 16, 2012
P3, N=88, Recruiting, Sponsor: Ottawa Hospital Research Institute
- | New P1/2 trial: Effect Of Acute Inflammatory Mediators On Functional Limitations In Patients With Acute Respiratory Failure (clinicaltrials.gov) - Oct 14, 2012
P1/2, N=100, Completed, Sponsor: Wake Forest University
- Enrollment change: Ascorbic Acid (Vitamin C) Infusion in Human Sepsis (clinicaltrials.gov) - Oct 10, 2012
P1/2, N=24, Completed, Sponsor: Virginia Commonwealth University
Not yet recruiting --> Recruiting N=30 --> 24
- Trial completion: Ascorbic Acid (Vitamin C) Infusion in Human Sepsis (clinicaltrials.gov) - Oct 10, 2012
P1/2, N=24, Completed, Sponsor: Virginia Commonwealth University
N=30 --> 24 Recruiting --> Completed
- | Trial initiation date: PROPPR: Pragmatic, Randomized Optimal Platelet and Plasma Ratios (clinicaltrials.gov) - Oct 3, 2012
P3, N=680, Completed, Sponsor: The University of Texas Health Science Center, Houston
Recruiting --> Completed Initiation date: Mar 2012 --> Aug 2012
- Enrollment change: Effect of Thiamine on Oxygen Utilization (VO2) in Critical Illness (clinicaltrials.gov) - Oct 3, 2012
P=N/A, N=20, Completed, Sponsor: Beth Israel Deaconess Medical Center
Initiation date: Mar 2012 --> Aug 2012 N=30 --> 20
- Trial completion: Effect of Thiamine on Oxygen Utilization (VO2) in Critical Illness (clinicaltrials.gov) - Oct 3, 2012
P=N/A, N=20, Completed, Sponsor: Beth Israel Deaconess Medical Center
N=30 --> 20 Recruiting --> Completed