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Acute Intermittent Porphyria
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3 Companies
1 Product
1 Product
0 Mechanisms of Action
0 Trials
11 News
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Givlaari
(givosiran) /
Alnylam
Trial primary completion date:
A Phase 1 Study of Givosiran (ALN-AS1) in Patients With Acute Intermittent Porphyria (AIP)
(clinicaltrials.gov) - Nov 27, 2017
P1
, N=40, Completed,
Sponsor: Alnylam Pharmaceuticals
Trial primary completion date: May 2017 --> Sep 2017
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Givlaari
(givosiran) /
Alnylam
Trial completion, Enrollment change:
A Phase 1 Study of Givosiran (ALN-AS1) in Patients With Acute Intermittent Porphyria (AIP)
(clinicaltrials.gov) - Sep 8, 2017
P1
, N=40, Completed,
Sponsor: Alnylam Pharmaceuticals
Trial primary completion date: May 2017 --> Sep 2017 Recruiting --> Completed | N=72 --> 40
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Givlaari
(givosiran) /
Alnylam
Enrollment change:
A Phase 1 Study of Givosiran (ALN-AS1) in Patients With Acute Intermittent Porphyria (AIP)
(clinicaltrials.gov) - Jun 5, 2017
P1
, N=72, Recruiting,
Sponsor: Alnylam Pharmaceuticals
Recruiting --> Completed | N=72 --> 40 N=48 --> 72
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chlorpromazine
/
Generic mfg.
Trial completion:
Assessment of Intra-subject Variability in the Bioavailability of Chlorpromazine Hydrochloride
(clinicaltrials.gov) - Dec 14, 2016
P1
, N=20, Completed,
Sponsor: Cycle Pharmaceuticals Ltd.
N=48 --> 72 Active, not recruiting --> Completed
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chlorpromazine
/
Generic mfg.
Enrollment closed:
Assessment of Intra-subject Variability in the Bioavailability of Chlorpromazine Hydrochloride
(clinicaltrials.gov) - Nov 22, 2016
P1
, N=20, Active, not recruiting,
Sponsor: Cycle Pharmaceuticals Ltd.
Active, not recruiting --> Completed Not yet recruiting --> Active, not recruiting
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Givlaari
(givosiran) /
Alnylam
Trial primary completion date:
A Phase 1 Study of Givosiran (ALN-AS1) in Patients With Acute Intermittent Porphyria (AIP)
(clinicaltrials.gov) - Oct 31, 2016
P1
, N=48, Recruiting,
Sponsor: Alnylam Pharmaceuticals
Not yet recruiting --> Active, not recruiting Trial primary completion date: Jun 2016 --> Feb 2017
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chlorpromazine
/
Generic mfg.
New P1 trial:
Assessment of Intra-subject Variability in the Bioavailability of Chlorpromazine Hydrochloride
(clinicaltrials.gov) - Oct 25, 2016
P1
, N=20, Not yet recruiting,
Sponsor: Cycle Pharmaceuticals Ltd.
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Givlaari
(givosiran) /
Alnylam
New P1 trial:
A Phase 1 Study of Givosiran (ALN-AS1) in Patients With Acute Intermittent Porphyria (AIP)
(clinicaltrials.gov) - May 22, 2015
P1
, N=48, Recruiting,
Sponsor: Alnylam Pharmaceuticals
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Trial completion, Gene therapy:
Phase I Gene Therapy Clinical Trial Using the Vector rAAV2/5-PBGD for the Treatment of Acute Intermittent Porphyria
(clinicaltrials.gov) - Dec 19, 2014
P1
, N=8, Completed,
Sponsor: Digna Biotech S.L.
Trial primary completion date: Jun 2016 --> Feb 2017 Active, not recruiting --> Completed
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New P1 trial, Gene therapy:
Phase I Gene Therapy Clinical Trial Using the Vector rAAV2/5-PBGD for the Treatment of Acute Intermittent Porphyria
(clinicaltrials.gov) - Mar 6, 2014
P1
, N=8, Active, not recruiting,
Sponsor: Digna Biotech S.L.
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Clinical:
Observational Study of Acute Intermittent Porphyria Patients
(clinicaltrials.gov) - Mar 2, 2014
P=N/A
, N=9, Completed,
Sponsor: Digna Biotech S.L.