- |||||||||| Neupogen (filgrastim) / Kyowa Kirin, Amgen
Phase classification, Enrollment change, Trial termination: Ex Vivo Expansion of Mafosfamide Purged CD34+ Cells in Patients With Acute Leukemia (clinicaltrials.gov) - Aug 23, 2018 P1, N=7, Terminated, Recruiting --> Completed | N=33 --> 11 | Trial completion date: Dec 2019 --> Dec 2017 | Trial primary completion date: Jul 2019 --> Dec 2017 Phase classification: P=N/A --> P1 | N=25 --> 7 | Active, not recruiting --> Terminated; Expiration of study supply
- |||||||||| Enrollment change, Trial completion date, Trial termination, Trial primary completion date: Donor Stem Cell Transplant in Treating Patients With High Risk Acute Myeloid Leukemia (clinicaltrials.gov) - Mar 31, 2018
P1, N=10, Terminated, Active, not recruiting --> Terminated; Lack of efficacy. N=35 --> 10 | Trial completion date: Mar 2019 --> Aug 2017 | Recruiting --> Terminated | Trial primary completion date: Mar 2018 --> Jul 2017; Insufficient Accrual
- |||||||||| Mektovi (binimetinib) / Ono Pharma, Pierre Fabre, Pfizer
Enrollment change, Trial termination, Trial primary completion date: MEK Inhibitor MEK162, Idarubicin, and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia (clinicaltrials.gov) - Dec 5, 2017 P1, N=1, Terminated, Active, not recruiting --> Completed | Trial primary completion date: Jun 2018 --> Jun 2017 N=19 --> 1 | Active, not recruiting --> Terminated | Trial primary completion date: Dec 2019 --> Feb 2015; logistics
- |||||||||| Biomarker, Trial completion, Trial initiation date, Trial primary completion date: Biomarkers in Blood Samples From Patients With Acute Myeloid Leukemia (clinicaltrials.gov) - May 17, 2017
P=N/A, N=220, Completed, Not yet recruiting --> Completed Not yet recruiting --> Completed | Initiation date: Aug 2011 --> Jan 2012 | Trial primary completion date: Sep 2011 --> Feb 2012
- |||||||||| Biomarker, Trial completion, Trial initiation date, Trial primary completion date: Biomarkers in Bone Marrow Samples From Patients With Acute Myeloid Leukemia (clinicaltrials.gov) - May 17, 2017
P=N/A, N=30, Completed, Not yet recruiting --> Completed | Initiation date: Aug 2011 --> Jan 2012 | Trial primary completion date: Sep 2011 --> Feb 2012 Not yet recruiting --> Completed | Initiation date: Sep 2010 --> May 2009 | Trial primary completion date: Oct 2010 --> Jun 2009
- |||||||||| Mekinist (trametinib) / Novartis, BeiGene, uprosertib (LAE003) / Laekna Therap
Enrollment closed, Enrollment change, Trial primary completion date, Combination therapy: Trametinib and Akt Inhibitor GSK2141795 in Treating Patients With Acute Myeloid Leukemia (clinicaltrials.gov) - Jun 5, 2016 P2, N=20, Active, not recruiting, Active, not recruiting --> Completed Recruiting --> Active, not recruiting | N=45 --> 20 | Trial primary completion date: May 2016 --> Jan 2016
- |||||||||| Mylotarg (gemtuzumab ozogamicin) / UCB, PDL, Pfizer
Biomarker, Trial completion, Trial primary completion date: Study of Gemtuzumab Ozogamicin Therapy in DNA Samples From Patients With Acute Myeloid Leukemia Treated on COG-AAML0531 (clinicaltrials.gov) - May 19, 2016 P=N/A, N=1000, Completed, Recruiting --> Active, not recruiting | N=45 --> 20 | Trial primary completion date: May 2016 --> Jan 2016 Active, not recruiting --> Completed | Trial primary completion date: Jan 2100 --> May 2016
- |||||||||| Biomarker, Trial completion, Trial primary completion date: Biomarkers in Samples From Young Patients With Acute Myeloid Leukemia (clinicaltrials.gov) - May 19, 2016
P=N/A, N=234, Completed, Active, not recruiting --> Completed | Trial primary completion date: Jan 2100 --> May 2016 Active, not recruiting --> Completed | Trial primary completion date: Jan 2100 --> May 2016
- |||||||||| Mektovi (binimetinib) / Ono Pharma, Pierre Fabre, Pfizer
Enrollment closed: MEK Inhibitor MEK162, Idarubicin, and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia (clinicaltrials.gov) - Apr 27, 2016 P1, N=19, Active, not recruiting, Suspended --> Active, not recruiting Suspended --> Active, not recruiting
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