Acne Vulgaris News - LARVOL Sigma

Acne Vulgaris

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27 Mechanisms of Action

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|||||||||| New P1 trial: A Study of JNJ 10229570-AAA to Evaluate Safety and Tolerability in Japanese Participants With Acne Vulgaris (clinicaltrials.gov) - Dec 13, 2011
P1, N=18, Completed, Sponsor: Janssen Pharmaceutical K.K.

||||||||||  minocycline extended release / Generic mfg., clindamycin/tretinoin / Generic mfg., isotretinoin / Generic mfg.
Trial completion:  Combination Treatment for Moderate to Severe Acne (clinicaltrials.gov) -  Nov 28, 2011
P4, N=97, Completed,  Sponsor: Medicis Global Service Corporation
Active, not recruiting --> Completed

||||||||||  tazarotene topical / Generic mfg.
Trial completion:  A Study to Evaluate the Safety and Efficacy of Tazarotene Foam, 0.1%, in Subjects With Common Facial Acne - W0260-301 (clinicaltrials.gov) -  Nov 13, 2011
P3, N=744, Completed,  Sponsor: Stiefel, a GSK Company
Active, not recruiting --> Completed Active, not recruiting --> Completed

||||||||||  tazarotene topical / Generic mfg.
Trial completion:  A Study to Evaluate the Safety and Efficacy of Tazarotene Foam, 0.1%, in Subjects With Common Facial Acne (clinicaltrials.gov) -  Nov 13, 2011
P3, N=742, Completed,  Sponsor: Stiefel, a GSK Company
Active, not recruiting --> Completed Active, not recruiting --> Completed

||||||||||  ethinyl estradiol/norgestimate / Generic mfg.
New P4 trial:  An Efficacy and Safety Study Comparing Oral Contraceptive Containing Norgestimate or Desogestrel for Acne Treatment (clinicaltrials.gov) -  Nov 6, 2011
P4, N=201, Completed,  Sponsor: Janssen-Cilag Ltd.,Thailand

||||||||||  dapsone / Generic mfg.
Trial completion, Monotherapy:  Dapsone Gel 5% and Tretinoin Gel 0.025% Versus Tretinoin Gel 0.025% Monotherapy for Facial Acne Vulgaris (clinicaltrials.gov) -  Oct 27, 2011
P4, N=163, Completed,  Sponsor: Allergan
Active, not recruiting --> Completed Active, not recruiting --> Completed

||||||||||  dapsone / Generic mfg., tazarotene topical / Generic mfg.
Trial completion, Monotherapy:  Dapsone Gel 5% and Tazarotene Cream 0.1% Versus Tazarotene Cream 0.1% Monotherapy for Facial Acne Vulgaris (clinicaltrials.gov) -  Oct 27, 2011
P4, N=171, Completed,  Sponsor: Allergan
Active, not recruiting --> Completed Active, not recruiting --> Completed

|||||||||| New P2 trial: Efficacy and the Tolerability of the Sequential Application of Two Marketed Products in Patients With Acne Vulgaris (clinicaltrials.gov) - Oct 26, 2011
P2, N=40, Completed, Sponsor: LEO Pharma

||||||||||  benzoyl peroxide/clindamycin / Generic mfg., clindamycin phosphate / Generic mfg.
Enrollment change:  W0261-101: A Phase 1, Single Center, Randomized, Open-Label Study to Evaluate the Bioavailability of Clindamycin From Clindamycin 1%-Benzoyl Peroxide 3% Gel, Topical Gel (Clindamycin 1%- Benzoyl Peroxide 5%), and Once Daily Gel (Clindamycin 1%-Benzoyl Peroxide 5%) in Subjects With Acne (clinicaltrials.gov) -  Oct 20, 2011
P1, N=0, Completed,  Sponsor: Stiefel, a GSK Company
Active, not recruiting --> Completed N=72 --> 0

|||||||||| Trial completion: A Novel Method to Improve Acne Outcomes (clinicaltrials.gov) - Oct 19, 2011
P=N/A, N=20, Completed, Sponsor: Wake Forest School of Medicine
N=72 --> 0 Active, not recruiting --> Completed

||||||||||  clindamycin/tretinoin / Generic mfg.
Enrollment change, Adherence:  Adherence to Study Medication Compared to Generic Topical Clindamycin Plus Generic Topical Tretinoin in Subjects With Mild to Moderate Acne Vulgaris (clinicaltrials.gov) -  Oct 13, 2011
P4, N=26, Completed,  Sponsor: Wake Forest School of Medicine
Active, not recruiting --> Completed N=40 --> 26

||||||||||  clindamycin/tretinoin / Generic mfg.
Trial completion, Adherence:  Adherence to Study Medication Compared to Generic Topical Clindamycin Plus Generic Topical Tretinoin in Subjects With Mild to Moderate Acne Vulgaris (clinicaltrials.gov) -  Oct 13, 2011
P4, N=26, Completed,  Sponsor: Wake Forest School of Medicine
N=40 --> 26 Active, not recruiting --> Completed

|||||||||| Trial completion: Obesity and Clinical Presentation of Hyperandrogenism (clinicaltrials.gov) - Oct 10, 2011
P=N/A, N=46, Completed, Sponsor: Taipei Medical University WanFang Hospital
Active, not recruiting --> Completed Recruiting --> Completed

|||||||||| Trial termination: UVA1 Light for Scleroderma and Similar Conditions (clinicaltrials.gov) - Oct 2, 2011
P=N/A, N=50, Terminated, Sponsor: University of Michigan
Recruiting --> Completed Active, not recruiting --> Terminated; inactivity

||||||||||  benzoyl peroxide/clindamycin / Generic mfg., clindamycin phosphate / Generic mfg.
New P3 trial:  Study STF115287, a Clinical Confirmation Study of GSK2585823 in the Treatment of Acne Vulgaris in Japanese Subjects (clinicaltrials.gov) -  Sep 29, 2011
P3, N=800, Completed,  Sponsor: GlaxoSmithKline

||||||||||  benzoyl peroxide/clindamycin / Generic mfg., clindamycin phosphate / Generic mfg.
New P1 trial:  Japanese Phase 1 Study of GSK2585823 (clinicaltrials.gov) -  Sep 1, 2011
P1, N=20, Completed,  Sponsor: GlaxoSmithKline

||||||||||  dapsone / Generic mfg., adapalene / Generic mfg.
New P1 trial:  Pharmacokinetics Study of Dapsone-Adapalene Fixed Combination Gel in Acne (clinicaltrials.gov) -  Aug 28, 2011
P1, N=0, Withdrawn,  Sponsor: Allergan