Imunon 
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 3 Products   49 Diseases  3 Products   6 Trials   198 News 
10 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
ThermoDox (lyso-thermosensitive liposomal doxorubicin) / Imunon
2015-000167-14: A clinical trial to evaluate the safety and efficacy for patients with localregional relapse in breast cancer scheduled to be treated with radiotherapy, hyperthermia and Lyso-Thermosenstive Liposomal Doxorubicin Uno studio clinico per valutare la sicurezza e l'efficacia per i pazienti con recidiva locale regionale nel cancro della mammella in programma di essere trattati con la radioterapia, ipertermia e liso-Thermosenstive doxorubicina liposomiale

Not yet recruiting
2
70
Europe
ThermoDox(R), Concentrate for solution for infusion
CELSION CORPORATION, Celsion Corporation
Local-Regional Relapse in Breast Cancer recidiva locoregionale in pazienti affette da carcinoma mammario, Breast Cancer Cancro al seno, Diseases [C] - Cancer [C04]
 
 
NCT04791228: A Pilot Study of Thermodox and MR-HIFU for Treatment of Relapsed Solid Tumors

Withdrawn
2
14
US
Magnetic Resonance-Guided High Intensity Focused Ultrasound, MR-HIFU, Lyso-thermosensitive Liposomal Doxorubicin, LTLD, ThermoDox
Children's National Research Institute
Solid Tumors, Soft Tissue Sarcoma, Ewing Sarcoma, Malignant Epithelial Neoplasm, Rhabdomyosarcoma, Wilms Tumor, Hepatic Tumor, Germ Cell Tumor, Bone Metastases
12/24
12/24
NCT02536183: A Phase I Study of Lyso-thermosensitive Liposomal Doxorubicin and MR-HIFU for Pediatric Refractory Solid Tumors

Terminated
1
2
US
Magnetic resonance high intensity focused ultrasound, MR-HIFU, Lyso-thermosensitive liposomal doxorubicin, LTLD; ThermoDox
AeRang Kim
Pediatric Cancer, Solid Tumors, Rhabdomyosarcoma, Ewing Sarcoma, Soft Tissue Sarcomas, Osteosarcoma, Neuroblastoma, Wilms Tumor, Hepatic Tumor, Germ Cell Tumors
10/22
10/22
NCT03749850: Image-guided Targeted Doxorubicin Delivery With Hyperthermia to Optimize Loco-regional Control in Breast Cancer

Recruiting
1
12
Europe
LTLD, ThermoDox, Lyso-Thermosensitive Liposomal Doxorubicin, MR-HIFU induced hyperthermia, MR-HIFU, Magnetic Resonance guided High Intensity Focused Ultrasound, MLHT, Mild local hyperthermia, Cyclophosphamide, Endoxan
UMC Utrecht, Dutch Cancer Society, Center for Translational Molecular Medicine, Vrienden UMC Utrecht
Metastatic Breast Cancer, Breast Cancer, Breast Neoplasms, Stage IV Breast Cancer, Metastatic Cancer, Invasive Ductal Carcinoma of Female Breast, Invasive Ductal Breast Cancer, Adenocarcinoma Breast
11/22
11/22
PanDox, NCT04852367: Targeted Doxorubicin in Pancreatic Tumours

Withdrawn
1
18
Europe
Focused Ultrasound, Doxorubicin, ThermoDox
University of Oxford, National Institute for Health Research, United Kingdom, Imunon
Pancreatic Ductal Adenocarcinoma, Pancreatic Cancer Stage IV, Pancreatic Cancer Non-resectable, Pancreatic Cancer Metastatic
03/23
03/23
IMNN-001 / Imunon
OVATION-3, NCT06915025: Phase 3 Trial Evaluating the Safety & Efficacy of IMNN-001 Administered in Combination w/ Standard NACT & Adjuvant Chemotherapy in Newly Diagnosed Patients w/ Advanced EOC, Fallopian Tube or Primary Peritoneal Cancer

Recruiting
3
500
US
IMNN-001 (IL-12 Plasmid Formulated with PEG-PEI-Cholesterol Lipopolymer), GEN-1, Paclitaxel, Carboplatin, Olaparib, Lynparza, Niraparib, Zejula
Imunon
Epithelial Ovarian Cancer, Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Carcinoma
10/32
10/32
OVATION 2, NCT03393884: Study of IMNN-001 (Also Known as GEN-1) With NACT for Treatment of Ovarian Cancer

Checkmark Presentation of OVATION 2 data in advanced ovarian cancer
Mar 2021 - Mar 2021: Presentation of OVATION 2 data in advanced ovarian cancer
Active, not recruiting
1/2
130
Canada, US
IMNN-001, Carboplatin, Paclitaxel
Imunon
Epithelial Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Cancer
07/24
11/25
MRD, NCT05739981: Phase II IMNN-001 (Also Known as GEN-1) on SLL With BEV and NACT, Newly Diagnosed Advanced Ovarian, Fallopian Tube or Primary Peritoneal Cancer

Recruiting
1/2
50
US
Paclitaxel, Carboplatin, Bevacizumab, IMNN-001
Imunon, Breakthrough Cancer Research
Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Cancer
08/26
01/28
NCT01673477: Study Of Intraperitoneal EGEN-001 Administered In Combination With Pegylated Liposomal-Doxorubicin In Patients With Recurrent Or Persistent Epithelial Ovarian, Fallopian Tube Or Peritoneal Cancer

Recruiting
1
18
US
EGEN-001 (IL-12 PLASMID FORMULATED WITH LIPOPOLYMER), Pegylated Liposomal Doxorubicin (PLD), Doxil And Lipodox
EGEN, Inc.
Epithelial Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Carcinoma
12/13
12/13
IMNN-101 / Imunon
NCT06283459: Study to Evaluate the Safety & Immunogenicity of IMNN-101 Administered in Healthy Adults Previously Vaccinated Against SARS-CoV-2

Active, not recruiting
1/2
74
US
IMNN-101
Imunon
SARS CoV 2 Infection
09/25
09/25
IMNN-102 / Imunon
No trials found
PL-Z / Imunon
No trials found
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
ThermoDox (lyso-thermosensitive liposomal doxorubicin) / Imunon
2015-000167-14: A clinical trial to evaluate the safety and efficacy for patients with localregional relapse in breast cancer scheduled to be treated with radiotherapy, hyperthermia and Lyso-Thermosenstive Liposomal Doxorubicin Uno studio clinico per valutare la sicurezza e l'efficacia per i pazienti con recidiva locale regionale nel cancro della mammella in programma di essere trattati con la radioterapia, ipertermia e liso-Thermosenstive doxorubicina liposomiale

Not yet recruiting
2
70
Europe
ThermoDox(R), Concentrate for solution for infusion
CELSION CORPORATION, Celsion Corporation
Local-Regional Relapse in Breast Cancer recidiva locoregionale in pazienti affette da carcinoma mammario, Breast Cancer Cancro al seno, Diseases [C] - Cancer [C04]
 
 
NCT04791228: A Pilot Study of Thermodox and MR-HIFU for Treatment of Relapsed Solid Tumors

Withdrawn
2
14
US
Magnetic Resonance-Guided High Intensity Focused Ultrasound, MR-HIFU, Lyso-thermosensitive Liposomal Doxorubicin, LTLD, ThermoDox
Children's National Research Institute
Solid Tumors, Soft Tissue Sarcoma, Ewing Sarcoma, Malignant Epithelial Neoplasm, Rhabdomyosarcoma, Wilms Tumor, Hepatic Tumor, Germ Cell Tumor, Bone Metastases
12/24
12/24
NCT02536183: A Phase I Study of Lyso-thermosensitive Liposomal Doxorubicin and MR-HIFU for Pediatric Refractory Solid Tumors

Terminated
1
2
US
Magnetic resonance high intensity focused ultrasound, MR-HIFU, Lyso-thermosensitive liposomal doxorubicin, LTLD; ThermoDox
AeRang Kim
Pediatric Cancer, Solid Tumors, Rhabdomyosarcoma, Ewing Sarcoma, Soft Tissue Sarcomas, Osteosarcoma, Neuroblastoma, Wilms Tumor, Hepatic Tumor, Germ Cell Tumors
10/22
10/22
NCT03749850: Image-guided Targeted Doxorubicin Delivery With Hyperthermia to Optimize Loco-regional Control in Breast Cancer

Recruiting
1
12
Europe
LTLD, ThermoDox, Lyso-Thermosensitive Liposomal Doxorubicin, MR-HIFU induced hyperthermia, MR-HIFU, Magnetic Resonance guided High Intensity Focused Ultrasound, MLHT, Mild local hyperthermia, Cyclophosphamide, Endoxan
UMC Utrecht, Dutch Cancer Society, Center for Translational Molecular Medicine, Vrienden UMC Utrecht
Metastatic Breast Cancer, Breast Cancer, Breast Neoplasms, Stage IV Breast Cancer, Metastatic Cancer, Invasive Ductal Carcinoma of Female Breast, Invasive Ductal Breast Cancer, Adenocarcinoma Breast
11/22
11/22
PanDox, NCT04852367: Targeted Doxorubicin in Pancreatic Tumours

Withdrawn
1
18
Europe
Focused Ultrasound, Doxorubicin, ThermoDox
University of Oxford, National Institute for Health Research, United Kingdom, Imunon
Pancreatic Ductal Adenocarcinoma, Pancreatic Cancer Stage IV, Pancreatic Cancer Non-resectable, Pancreatic Cancer Metastatic
03/23
03/23
IMNN-001 / Imunon
OVATION-3, NCT06915025: Phase 3 Trial Evaluating the Safety & Efficacy of IMNN-001 Administered in Combination w/ Standard NACT & Adjuvant Chemotherapy in Newly Diagnosed Patients w/ Advanced EOC, Fallopian Tube or Primary Peritoneal Cancer

Recruiting
3
500
US
IMNN-001 (IL-12 Plasmid Formulated with PEG-PEI-Cholesterol Lipopolymer), GEN-1, Paclitaxel, Carboplatin, Olaparib, Lynparza, Niraparib, Zejula
Imunon
Epithelial Ovarian Cancer, Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Carcinoma
10/32
10/32
OVATION 2, NCT03393884: Study of IMNN-001 (Also Known as GEN-1) With NACT for Treatment of Ovarian Cancer

Checkmark Presentation of OVATION 2 data in advanced ovarian cancer
Mar 2021 - Mar 2021: Presentation of OVATION 2 data in advanced ovarian cancer
Active, not recruiting
1/2
130
Canada, US
IMNN-001, Carboplatin, Paclitaxel
Imunon
Epithelial Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Cancer
07/24
11/25
MRD, NCT05739981: Phase II IMNN-001 (Also Known as GEN-1) on SLL With BEV and NACT, Newly Diagnosed Advanced Ovarian, Fallopian Tube or Primary Peritoneal Cancer

Recruiting
1/2
50
US
Paclitaxel, Carboplatin, Bevacizumab, IMNN-001
Imunon, Breakthrough Cancer Research
Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Cancer
08/26
01/28
NCT01673477: Study Of Intraperitoneal EGEN-001 Administered In Combination With Pegylated Liposomal-Doxorubicin In Patients With Recurrent Or Persistent Epithelial Ovarian, Fallopian Tube Or Peritoneal Cancer

Recruiting
1
18
US
EGEN-001 (IL-12 PLASMID FORMULATED WITH LIPOPOLYMER), Pegylated Liposomal Doxorubicin (PLD), Doxil And Lipodox
EGEN, Inc.
Epithelial Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Carcinoma
12/13
12/13
IMNN-101 / Imunon
NCT06283459: Study to Evaluate the Safety & Immunogenicity of IMNN-101 Administered in Healthy Adults Previously Vaccinated Against SARS-CoV-2

Active, not recruiting
1/2
74
US
IMNN-101
Imunon
SARS CoV 2 Infection
09/25
09/25
IMNN-102 / Imunon
No trials found
PL-Z / Imunon
No trials found

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