Cantex Pharma Trials - LARVOL Sigma

Trial + Data / Events

Status

Region

Interventions

Sponsor

Conditions

Primary compl

Study compl

dociparstat sodium (CX-01) / Cantex Pharma, Chimerix

Chimerix_COVID-19: Chimerix Announces Initiation of a Phase 2/3 Study of DSTAT in Acute Lung Injury for Patients with Severe COVID-19

Not yet recruiting

450

dociparstat sodium (CX-01) - Chimerix

Cantex, Chimerix

Severe COVID-19

NCT04571645: Dociparstat in Combination With Standard Chemotherapy for the Treatment of Acute Myeloid Leukemia

Terminated

Dociparstat, DSTAT, CX-01, 2-0,3-0 desulfated heparin, ODSH, dociparstat sodium, Control, 0.9% Normal Saline, Normal saline, Sodium chloride 0.9%

Chimerix

Acute Myeloid Leukemia

05/22

azeliragon (TTP488) / Cantex Pharma

2017-004065-27: Clinical Study to assess the Safety And Efficacy Of Investigational Medicinal Product Azeliragon (TTP488) In Patients With Mild Alzheimer's Disease who have previously completed a Clinical Trial with Azeliragon (TP488)

Not yet recruiting

800

Europe

Azeliragon, TTP488, Capsule, hard

vTv THERAPEUTICS LLC, vTv THERAPEUTICS LLC

MILD ALZHEIMER'S DISEASE, MILD ALZHEIMER'S DISEASE, Diseases [C] - Nervous System Diseases [C10]

NCT05815485: A Randomized, Double-Blind, Placebo-Controlled Phase 2/3 Study to Determine the Safety and Effectiveness of Azeliragon in the Treatment of Patients Hospitalized for Coronavirus Disease 2019 (COVID-19) or Pneumonia

Recruiting

2/3

144

Azeliragon, Placebo

Salim S. Hayek

COVID-19

04/26

NCT05986851: Azeliragon in MGMT Unmethylated Glioblastoma

Recruiting

Azeliragon

Cantex Pharmaceuticals, Medpace, Inc.

Glioblastoma

09/24

06/25

2022-002801-36: Azeliragon in Glioblastoma Azeliragon en Glioblastoma

Not yet recruiting

1/2

Europe

Azeliragon, TTP488, Capsule

Cantex Pharmaceuticals Inc., Cantex Pharmaceuticals Inc.

Newly diagnosed glioblastoma Glioblastoma de reciente diagnóstico, Glioblastoma Glioblastoma, Diseases [C] - Cancer [C04]

CAN-201 NDG, NCT05635734: Azeliragon and Chemoradiotherapy in Newly Diagnosed Glioblastoma

Recruiting

1/2

Europe

Azeliragon 5 mg, Azeliragon 10 mg, Azeliragon 20 mg

Cantex Pharmaceuticals

Glioblastoma

12/24

12/25

NCT05766748: Study of Effect of Azeliragon in Patients Refractory to Prior Treatment of Metastatic Pancreatic Cancer

Recruiting

1/2

Azeliragon, TTP488

Cantex Pharmaceuticals

Metastatic Pancreatic Cancer

02/25

05/25

RAGE, NCT05256745: Inhibition to Decrease Cardiotoxicity in Women With Early Breast Cancer

Recruiting

1/2

TTP488, Azeliragon, ddAC/ddT, Dose dense doxorubicin plus cyclophosphamide, dose dense paclitaxel, TC, Docetaxel plus cyclophosphamide, TCHP, Docetaxel, carboplatin, trastuzumab, and pertuzumab, Chemotherapy regimen that includes ddAC, Dose dense doxorubicin plus cyclophosphamide

Georgetown University

Cancer Related Cognitive Decline, Non-metastatic Breast Cancer

11/24

ADORATION, NCT05789589: Effect of Azeliragon Combined With Stereotactic Radiation Therapy in Patients With Brain Metastases

Recruiting

1/2

Azeliragon, TTP488, PF-04494700, Stereotactic radiosurgery, Corticosteroid, dexamethasone, methylprednisolone

Baptist Health South Florida, Miami Cancer Institute, Cantex Pharmaceuticals Inc.

Cancer, Metastasis, Metastatic Cancer, Brain Metastases, Brain Metastases, Adult

10/25

08/27

NCT05773664: Dexamethasone and Azeliragon for Management of Post-Resection Cerebral Edema in Patients With Glioblastoma

Not yet recruiting

Azeliragon, Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized Tomography, CT, CT Scan, tomography, Dexamethasone, Aacidexam, Adexone, Aknichthol Dexa, Alba-Dex, Alin, Alin Depot, Alin Oftalmico, Amplidermis, Anemul mono, Auricularum, Auxiloson, Baycadron, Baycuten, Baycuten N, Cortidexason, Cortisumman, Decacort, Decadrol, Decadron, Decadron DP, Decalix, Decameth, Decasone R.p., Dectancyl, Dekacort, Deltafluorene, Deronil, Desamethasone, Desameton, Dexa-Mamallet, Dexa-Rhinosan, Dexa-Scheroson, Dexa-sine, Dexacortal, Dexacortin, Dexafarma, Dexafluorene, Dexalocal, Dexamecortin, Dexameth, Dexamethasone Intensol, Dexamethasonum, Dexamonozon, Dexapos, Dexinoral, Dexone, Dinormon, Dxevo, Fluorodelta, Fortecortin, Gammacorten, Hemady, Hexadecadrol, Hexadrol, Lokalison-F, Loverine, Methylfluorprednisolone, Millicorten, Mymethasone, Orgadrone, Spersadex, TaperDex, Visumetazone, ZoDex, Magnetic Resonance Imaging of the Brain with and without Contrast, Brain Magnetic Resonance Imaging with and without Contrast, Brain MRI, Brain MRI with and without Contrast, Head MRI with and without Contrast

City of Hope Medical Center, National Cancer Institute (NCI)

Glioblastoma, Malignant Glioma

11/24



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