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12 Trials

   

Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
obexelimab (ZB012) / Zenas BioPharma
INDIGO, NCT05662241: A Phase 3 Study of Obexelimab in Patients With IgG4-Related Disease

Recruiting
3
200
Europe, Canada, Japan, US, RoW
Obexelimab, Placebo
Zenas BioPharma (USA), LLC
IgG4 Related Disease
10/25
12/26
NCT05786573: A Study of Obexelimab in Patients With Warm Autoimmune Hemolytic Anemia (SApHiAre)

Recruiting
3
134
Europe, Japan, US, RoW
Obexelimab, Placebo
Zenas BioPharma (USA), LLC
Warm Autoimmune Hemolytic Anemia
03/26
06/26
NCT06564311: A Study of Obexelimab in Patients With Relapsing Multiple Sclerosis (MoonStone)

Recruiting
2
93
US
Obexelimab, Placebo
Zenas BioPharma (USA), LLC
Relapsing Multiple Sclerosis
08/25
12/25
SunStone, NCT06559163: A Study of Obexelimab in Patients with Systemic Lupus Erythematosus

Recruiting
2
190
US
Obexelimab, Placebo
Zenas BioPharma (USA), LLC
Systemic Lupus Erythematosus
11/25
03/26
VRDN-001 / Viridian Therap
VRDN-001-302, NCT06179875: An Open-label Study for Participants Who Are Non-responders at the End of Treatment Assessment on the VRDN-001-101 and VRDN-001-301 Pivotal Studies

Recruiting
3
143
Europe, US
Intervention/Treatment
Viridian Therapeutics, Inc.
Thyroid Eye Disease
07/25
03/26
STRIVE, NCT06384547: A Randomized, Active Controlled, Safety and Tolerability Study of VRDN-001 in Participants With Thyroid Eye Disease (TED)

Recruiting
3
212
US
VRDN-001 10 mg/kg, VRDN-001 3 mg/kg
Viridian Therapeutics, Inc.
Thyroid Eye Disease
05/25
01/26
THRIVE, NCT05176639: A Safety, Tolerability and Efficacy Study of Veligrotug (VRDN 001) in Healthy Volunteers and Participants with Thyroid Eye Disease (TED) ( )

Active, not recruiting
3
154
Europe, Canada, US, RoW
Veligrotug (VRDN-001) Phase 1/2 MAD (HV and TED), VRDN-001 Phase 3 Cohort (THRIVE), VRDN-001 Placebo
Viridian Therapeutics, Inc.
Thyroid Eye Disease
07/24
03/25
THRIVE-2, NCT06021054: An Efficacy, Safety, and Tolerability Study of Veligrotug (VRDN-001), in Participants with Chronic Thyroid Eye Disease (TED)

Active, not recruiting
3
188
Europe, US, RoW
Veligrotug (VRDN-001), Placebo
Viridian Therapeutics, Inc.
Thyroid Eye Disease
12/24
09/25
2021-006794-37: A Safety, Tolerability and Efficacy Study of VRDN 001

Not yet recruiting
2/3
184
Europe
VRDN-001, VRDN-001, Concentrate for solution for infusion
Viridian Therapeutics, Inc., Viridian Therapeutics, Inc.
Thyroid eye disease (TED), Thyroid eye disease (TED), Diseases [C] - Eye Diseases [C11]
 
 
NCT05542303: A Safety, Tolerability and Pharmacokinetics Study of ZB001 in Healthy Subjects

Completed
1
24
RoW
ZB001 for injection
Zenas BioPharma (USA), LLC
Healthy Volunteers
04/23
04/23
NCT05776121: Study of ZB001 in Chinese Patients With Thyroid Eye Disease

Active, not recruiting
1
17
RoW
ZB001 for injection
Zenas BioPharma (USA), LLC
Thyroid Eye Disease
10/24
10/24
adalimumab biobetter (ZB002) / Zenas BioPharma
NCT05638854: A Study to Evaluate Safety and Pharmacokinetics of ZB002 in Healthy Participants and Participants with Rheumatoid Arthritis

Recruiting
1
72
RoW
ZB002, Placebo
Zenas BioPharma (USA), LLC
Healthy Volunteers, Rheumatoid Arthritis
07/25
07/25

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