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6 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
PfSPZ-CVac / Sanaria
NCT03503058: Safety, Tolerability, Immunogenicity and Protective Efficacy of PfSPZ Vaccine and PfSPZ-CVac in Indonesian Adults Against Naturally-Transmitted Malaria

Recruiting
2
372
RoW
PfSPZ Vaccine, PfSPZ Challenge under chloroquine (CQ) chemoprophylaxis, PfSPZ-CVac, Normal Saline, NS, Chloroquine chemoprophylaxis alone, CQ
Sanaria Inc., Eijkman Oxford Clinical Research Unit, Indonesia, Indonesia University, Congressionally Directed Medical Research Programs
Malaria
07/24
12/24
2018-004523-36: Testing the protection by a Plasmodium falciparum sporozoite Chemoprophylaxis Vaccine (PfSPZ-CVac), using a simplified regimen in healthy and malaria-naive adults in Germany

Not yet recruiting
1/2
21
Europe
aseptic, purified, cryopreserved Plasmodium falciparum (Pf) sporozoites (SPZ) NF54 (PfSPZ Challenge), Resochin, aseptic, purified, cryopreserved Plasmodium falciparum (Pf) sporozoites (SPZ) 7G8 (PfSPZ Challenge), PfSPZ Challenge NF54, PfSPZ Challenge 7G8, Injection, Tablet, Resochin
University Clinics Tübingen, Universtiy Clinics Tübingen
Immunization of healthy volunteers against P. falciparum infection, Vaccine against malaria infection in healthy volunteers, Diseases [C] - Parasitic Diseases [C03]
 
 
NCT05441410: Comparing Safety and Protective Efficacy of Vaccine Candidate PfSPZ-CVac and MVA ME-TRAP/ ChAd63 ME-TRAP in Adults

Not yet recruiting
1/2
30
NA
Pyronaridine Tetraphosphate, Artesunate Drug Combination, Pyramax, PfSPZ Challenge (NF54), MVA ME-TRAP, ChAd63 ME-TRAP, Sodium chloride (NaCl) 0.9%, Placebo: Saline
University Hospital Tuebingen, Sanaria Inc., University of Oxford
Malaria
10/25
10/25
PfSPZ Vaccine / Sanaria
NCT03989102: Safety, Immunogenicity, and Protective Efficacy of Radiation Attenuated Plasmodium Falciparum NF54 Sporozoites (PfSPZ Vaccine) During Malaria Transmission Season in Healthy African Adult Women of Childbearing Potential in Mali

Completed
2
324
RoW
PfSPZ Vaccine, Normal Saline
National Institute of Allergy and Infectious Diseases (NIAID), Malaria Research and Training Center, University of Science Techniques and Technologies of Bamako Sanaria Inc.
Malaria
04/22
03/23
NCT04940130: PfSPZ Vaccine Trial in Malian Children

Completed
2
290
RoW
Sanaria® PfSPZ Vaccine, Normal Saline
Sanaria Inc., Malaria Research and Training Center, Bamako, Mali, University of the Sciences, Techniques and Technologies of Bamako, National Institute of Allergy and Infectious Diseases (NIAID)
Malaria, Malaria,Falciparum
12/22
12/22
NCT05604521: A Phase 1 Trial of PfSPZ Vaccine in Healthy Adults to Determine Safety, Tolerability and Efficacy Against Heterologous CHMI

Terminated
1
60
US
PfSPZ Vaccine, PfSPZ Challenge (7G8), Normal Saline, Placebo
Sanaria Inc., University of Maryland, Baltimore
Malaria, Malaria,Falciparum
09/23
09/23

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