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Trial + Data / Events	Status	Ph	N	Region	Interventions	Sponsor	Conditions	Primary compl	Study compl
AFA-281 / AfaSci
AFA-281-304, NCT06710431: A Study of the Safety and Exploratory Efficacy of Oral AFA-281 in Patients with Alcohol Use Disorder	Not yet recruiting	2	36	US	AFA-281	Afasci Inc	Alcohol Abuse, Alcohol Abuse/addiction, Anxiety, Pain Threshold, Depression Disorders, Sleep Disorder	06/27	12/27
AFA-281-202, NCT06649747: Safety and Efficacy Study on AFA-281 for the Treatment of Low Back Pain	Not yet recruiting	2	408	NA	AFA-281	Afasci Inc	Lumbosacral Radiculopathy	03/32	03/32
NCT05547503: Phase I Single Ascending Dose and Multiple Ascending Doses of Oral AFA-281 in Healthy Volunteers	Recruiting	1	58	US	AFA-281	Afasci Inc, Cognitive Research Corporation	Pain, Neuropathic, Pain, Inflammatory	08/25	08/25
NCT06719908: A Phase I Study of the Interaction of Alcohol With Oral AFA-281 in Healthy Volunteers	Not yet recruiting	1	20	NA	AFA-281 is a small molecule, orally available, Alcohol (Ethanol)	Afasci Inc	Alcohol, Alcohol Use Disorders	07/26	09/29

Trial + Data / Events	Status	Ph	N	Region	Interventions	Sponsor	Conditions	Primary compl	Study compl
AFA-281 / AfaSci
AFA-281-304, NCT06710431: A Study of the Safety and Exploratory Efficacy of Oral AFA-281 in Patients with Alcohol Use Disorder	Not yet recruiting	2	36	US	AFA-281	Afasci Inc	Alcohol Abuse, Alcohol Abuse/addiction, Anxiety, Pain Threshold, Depression Disorders, Sleep Disorder	06/27	12/27
AFA-281-202, NCT06649747: Safety and Efficacy Study on AFA-281 for the Treatment of Low Back Pain	Not yet recruiting	2	408	NA	AFA-281	Afasci Inc	Lumbosacral Radiculopathy	03/32	03/32
NCT05547503: Phase I Single Ascending Dose and Multiple Ascending Doses of Oral AFA-281 in Healthy Volunteers	Recruiting	1	58	US	AFA-281	Afasci Inc, Cognitive Research Corporation	Pain, Neuropathic, Pain, Inflammatory	08/25	08/25
NCT06719908: A Phase I Study of the Interaction of Alcohol With Oral AFA-281 in Healthy Volunteers	Not yet recruiting	1	20	NA	AFA-281 is a small molecule, orally available, Alcohol (Ethanol)	Afasci Inc	Alcohol, Alcohol Use Disorders	07/26	09/29