| ByFavo (remimazolam) / PAION, Cosmo Pharma, Mundipharma, Pharmascience, Eagle Pharma |
ACTRN12623000133639: Continuous infusion of remimazolam for intraoperative sedation as a safe and effective option: a prospective clinical study. |
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| Not yet recruiting | 4 | 50 | | | Antonia Kustura, MD, University Hospital Center Sestre milosrdnice | Procedural or intraoperative sedation. | | | | |
ACTRN12624001124527: Comparing the safety and effectiveness of remimazolam and propofol for general anesthesia. |
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| Not yet recruiting | 4 | 60 | | | University Hospital Center Sestre milosrdnice, University Hospital Center Sestre milosrdnice | General anesthesia | | | | |
ChiCTR2000034121: The efficacy and safety of remimazolam injection for painless abortion |
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| Not yet recruiting | 4 | 60 | | IV propofol ;IV remimazolam | the Affiliated Hospital of Guizhou Medical University; The Affiliated Hospital of Guizhou Medical University, self-funding | painless abortion anesthesia | | | | |
ChiCTR2000035388: Effect of efficacy and safety study of remimazolam in ultrasound-guided nerve block: a randomized controlled trial. |
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| Recruiting | 4 | 75 | | Remimazolam ;Dexmedetomidine ;Midazolam | Department of Anesthesiology, Anhui Provincial Cancer Hospital; Anhui Provincial Cancer Hospital, Self-financing | Anesthetic | | | | |
ChiCTR2000035555: Comparison of safety and efficacy of different doses of remimazolam combined with sufentanil in the assisted sedation of ultrasound-guided nerve block |
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| Recruiting | 4 | 75 | | 3mg remimazolam ;4mg Remimazolam ;5mg Remimazolam | Department of Anesthesiology, Anhui Provincial Cancer Hospital; Anhui Provincial Cancer Hospital, Self-financing | Anesthetic | | | | |
ChiCTR2000030409: Observation on Comparison of the anaesthesia effect of remimazolam and propofol in the off-pump coronary artery bypass grafting surgery |
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| Recruiting | 4 | 60 | | Intravenous remimazolam 0.1-0.2mg/kg during anesthesia induction, continuous intravenous infusion 1-2mg/(kg.h) of remimazolam during operation. ;Intravenous propofol 1-2mg/kg during anesthesia induction, continuous intravenous infusion 1-2mg/(kg.h) of propofol during operation. | The Affiliated Yantai Yuhuangding Hospital of Qingdao University; The Affiliated Yantai Yuhuangding Hospital of Qingdao University, none | coronary heart disease | | | | |
ChiCTR2000030440: Clinical study on the application of remimazolam in laparoscopic cholecystectomy under general anesthesia |
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| Not yet recruiting | 4 | 60 | | Intravenous remimazolam 0.1-0.2mg/kg during anesthesia induction, continuous intravenous infusion 1-2mg/ (kg.h) of remimazolam during operation. ;Intravenous propofol 1-2mg/kg during anesthesia induction, continuous intravenous infusion 1-2mg/(kg.h) of propofol during operation. | The Affiliated Yantai Yuhuangding Hospital of Qingdao University; The Affiliated Yantai Yuhuangding Hospital of Qingdao University, None | Cholelithiasis | | | | |
ChiCTR2100045492: Effect observation of remimazolam benzenesulfonate combined with alfentanil in fiberoptic bronchoscopy |
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| Recruiting | 4 | 100 | | remimazolam benzenesulfonate ;propofol | The First Affiliated Hospital of Zhengzhou University; The First Affiliated Hospital of Zhengzhou University, self-raised | pain | | | | |
ChiCTR2000031965: Remimazolam or Dexmedetomidine for Sedation During Awake Fibreoptic Nasal Intubation: A Randomised Controlled Trial |
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| Completed | 4 | 43 | | Remimazolam ;dexmedetomidine | The First Affiliated Hospital of Zhengzhou University; The First Affiliated Hospital of Zhengzhou University, None | Difficult airway | | | | |
ChiCTR2000041568: Effect of Remimazolam versus Propofol on the Quality of Recovery After Colonoscopy: a Randomized Controlled Trial |
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| Recruiting | 4 | 158 | | Give the initial dose of 5.0 mg of remimazolam. If sufficient sedation is not obtained, inject supplementary doses of remimazolam (2.5 mg per dose), and the supplement interval must be more than 1 minute. Give up to 5 doses of remazolam within 15 minutes. ;Give the initial dose of 1.5 mg/kg of propofol. If sufficient sedation is not obtained, inject supplementary doses of propofol (0.5mg/kg per dose), and the supplement interval must be more than 1 minute. Give up to 5 doses of propofol within 15 minutes. | Affiliated Hospital of Xuzhou Medical University; Affiliated Hospital of Xuzhou Medical University, Own expense | Colonoscopy | | | | |
ChiCTR2100041686: The comparison of remimazolam and propofol for pediatric gastroscopy sedation: a single center random control study |
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| Recruiting | 4 | 240 | | remimazolam ;propofol | Kunming Children's Hospital; Kunming Children's Hospital, self-collection | Pediatric Gastroscopy | | | | |
ChiCTR2000039343: Effective Dose of Remimazolam Besylate for Sedation in Postoperative Mechanically Ventilated ICU Patients Undergoing Noncardiac Surgery |
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| Recruiting | 4 | 72 | | Remimazolam 0.5mg/kg/h ;Remimazolam 1mg/kg/h ;Remimazolam 1.5mg/kg/h ;Remimazolam 2mg/kg/h ;Remimazolam 2.5mg/kg/h ;Remimazolam 3mg/kg/h | Department of Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; Department of Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, self-raised | ICU agitation | | | | |
ChiCTR2000041551: The effect of remimazolam combined with alfentanil in gastrointestinal endoscopic procedures sedation: a prospective study |
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| Recruiting | 4 | 2000 | | Intravenous remazolam ;Intravenous alfentanil | The First Affiliated Hospital of Zhengzhou University; The First Affiliated Hospital of Zhengzhou University, Self-raised | Postoperative central nervous system dysfunction | | | | |
ChiCTR2100052425: Interactions between remimazolam and propofol in combination with sufentanil for anesthesia during gastroscopy |
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| Completed | 4 | 200 | | administered remimazolam in combination with 0.1 ug/kg sufentanil ;administered propofol in combination with 0.1 ug/kg sufentanil ;administered propofol in combination with 0.1 ug/kg sufentanil and 0.25 median effective dose (ED50) remimazolam ;administered propofol in combination with 0.1 ug/kg sufentanil and 0.5 ED50 remimazolam ;administered propofol in combination with 0.1 ug/kg sufentanil and 0.75 ED50 remimazolam | The Second Affiliated Hospital of Hainan Medical University; The Second Affiliated Hospital of Hainan Medical University, Hainan Province Clinical Medical Center and Hainan Provincial Health Commission | Gastrointestinal diseases | | | | |
ChiCTR2100041986: Effect of general anesthesia with remimazolam on the quality of patients’ recovery after urologic surgery: a randomized controlled trial |
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| Recruiting | 4 | 166 | | anesthesia induction with (0.2-0.3)mg/kg remimazolam and maintenance with (1-2)mg/kg/h remimazolam ;anesthesia induction with (2-3)mg/kg propofol and maintenance with (4-10)mg/kg/h propofol | The First Affiliated Hospital of Zhengzhou University; The First Affiliated Hospital of Zhengzhou University, self-raised | Surgical treatment of Urologic Diseases | | | | |
ChiCTR2100043964: Prospective Study of Remimazolam Besylate Combined with Alfentanil in Gastrointestinal Endoscopy Under Sedation |
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| Recruiting | 4 | 1000 | | Propofol 1.5mg/kg ;Remimazolam Besylate 0.05mg/kg ;Remimazolam Besylate 0.1mg/kg ;Remimazolam Besylate 0.15mg/kg | The First Affiliated Hospital of Zhengzhou University; The First Affiliated Hospital of Zhengzhou University, Bethune Foundation | Digestive Tract Disease | | | | |
ChiCTR2100046476: Sedation with remimazolam in elderly patients undergoing upper gastrointestinal endoscopy |
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| Recruiting | 4 | 100 | | Sedation with remimazolam ;Sedation with Propofol | The First Affiliated Hospital, School of Medicine, Zhejiang University; The First Affiliated Hospital, College of Medicine, Zhejiang University, Nil | Gastroscopy | | | | |
ChiCTR2000039076: Remimazolam contrast propofol application of gastroscopy in elderly patients |
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| Recruiting | 4 | 90 | | Reimazolam was administered under anesthesia ;Antagonism by flumazenil ;Propofol was administered under anesthesia | Guiqian International General Hospital; Guiqian International General Hospital, China foundation for the promotion of health | Gastroscopy | | | | |
NCT04621305: Remimazolam Reduces Emergence Delirium in Preschool Children Undergoing Laparoscopic Surgery by Sevoflurane Anesthesia |
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| Recruiting | 4 | 120 | RoW | normal saline, Placebo group, Bolus Remimazolam, Bolus group, Continuous Infusion Remimazolam, Continuous infusion group | Second Affiliated Hospital of Wenzhou Medical University | Emergence Delirium | 11/21 | 11/21 | | |
ChiCTR2000039704: A Comparison Between Lidocaine and remimazolam on the Prevention of propofol Injection pain during genel anesthesiology |
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| Recruiting | 4 | 300 | | Saline intravenous injection ;Lidocaine intravenous injection ;Remimazolam intravenous injection | The First Affiliated Hospital of Guangxi Medical University; The First Affiliated Hospital of Guangxi Medical University, Self-financing | Injection pain | | | | |
ChiCTR2000040041: The safety and efficacy of remimazolam anesthesia campared with propofol during endobronchial ultrasound-guided transbronchial needle aspiration：A ?prospective randomized controlled trial |
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| Completed | 4 | 118 | | injection propofol 40 mg/kg/h ;injection remimazolam 6 mg/kg/h | Fujian Medical University Union Hospital; Fujian Medical University Union Hospital, Fujian Medical Innovation Project (grant number 2019-CXB-6) | lung cancer | | | | |
ChiCTR2000040579: Efficacy and safety of remimazolam in elective general anesthesia in hypertensive patients: a single-center, randomized, controlled trial |
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| Not yet recruiting | 4 | 130 | | injection propofol for induction: 40mg/kg/h; for maintenance 6-8mg/kg/h ;injection remimazolam for induction: 6mg/kg/h; for maintenance 1-3mg/kg/h | Fujian Medical University Union Hospital; Fujian Medical University Union Hospital, Fujian Medical Innovation Project (grant number 2019-CXB-6) | hypertension | | | | |
ChiCTR2100052360: Determination of ED50 and ED95 for adequate sedation of single dose of remazolam in different people |
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| Not yet recruiting | 4 | 160 | | remimazolam ;remimazolam ;remimazolam ;remimazolam | the First Affiliated Hospital of Zhengzhou University; the First Affiliated Hospital of Zhengzhou University, self-funded | anaesthesia | | | | |
NCT04969068: The Median Effective Dose of Remimazolam for Duodenoscopy Insertion During ERCP With Alfentanil 10µg/kg |
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| Recruiting | 4 | 50 | RoW | Remimazolam | Tianjin Nankai Hospital | Anesthesia | 12/21 | 12/21 | | |
| Recruiting | 4 | 40 | | remimazolam | Taizhou Hospital of Zhejiang Province; Taizhou Hospital of Zhejiang Province, self-funding or from research funding | painless colonoscopy | | | | |
ChiCTR2100042044: A Study of remimazolam compared with propofol in the treatment of patients with esophageal varices under gastroscopy |
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| Recruiting | 4 | 284 | | remimazolam ;propofol | the First Affiliated Hospital of Nanchang University; The First Affiliated Hospital of Nanchang University, China Health Promotion Foundation | Gastroscopic anesthesia for esophageal varices | | | | |
ChiCTR2100041808: Application and effect of besylate remimazolam for interventional surgery in patients with intracranial aneurysms |
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| Recruiting | 4 | 90 | | The dose of besylate remimazolam was adjusted up and down according to the changes of MAP and HR. ;Group R: Remimazolam induction dose-0.3mg/kg, maintenance dose-2mg/kg/h, at the end of surgery remimazolam dose was adjusted to ED95 dose obtained from part Ⅰwhich could suppress extubation reaction effectively. Group P: Propofol induction dose-2.0mg/kg, maintenance dose-6mg/kg/h. | Shanxi Bethune hospital; Shanxi Bethune hospital, Bethune Charitable Foundation | Cerebral aneurysms | | | | |
ChiCTR2100045280: Determination of the 90% effective dose of Remimazolam for the endoscopy with general anaesthesia |
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| Recruiting | 4 | 80 | | Remimazolam ;Remimazolam | Guangzhou Women and Children's Medical Centre; Guangzhou Women and Children's Medical Centre, none | gastrointestinal disease | | | | |
ChiCTR2300070370: Effect of remimazolam versus propofol for the induction of general anesthesia on cerebral blood flow and oxygen saturation in elderly patients undergoing carotid endarterectomy |
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| Completed | 4 | 43 | | Remimazolam induction ;Propofol induction | Suzhou Dushu Lake Hospital (Dushu Lake Hospital affiliated to Soochow University); Suzhou Dushu Lake Hospital (Dushu Lake Hospital affiliated to Soochow University), Suzhou Science and Technology Bureau, Jiangsu, China（No. SZM2021002，No. SZM2021003） | carotid artery stenosis | | | | |
ChiCTR2100049314: A randomized, parallel controlled study comparing remazolam with propofol for therapeutic endoscopic retrograde cholangiopancreatography (ERCP) |
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| Not yet recruiting | 4 | 80 | | induction and maitainance by propofol ; induction and maitainance by remimazolam | The Second Xiangya Hospital, Central South University; The Second Xiangya Hospital, Central South University, self-raised | Biliary pancreatosis | | | | |
ChiCTR2100051912: To determine ED50 and ED95 of remimazolam toluenesulfonate to induce auxiliary sedation in elderly patients undergoing spinal anesthesia |
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| Recruiting | 4 | 40 | | Remimazolam | The Second Affiliated Hospital of Hainan Medical University; The Second Affiliated Hospital of Hainan Medical University, Self-raised | Anesthesia with electroresection of the prostate | | | | |
ChiCTR2100052615: Study on appropriate dose and safety and efficacy of remazolam besylate for painless colonoscopy |
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| Completed | 4 | 123 | | 0.2mg/kg Remimazolam was used as the induction dose ;2mg/kg Propofol was used as the induction dose ;0.25mg/kg Remimazolam was used as the induction dose | Hangzhou First People's Hospital affiliated to Zhejiang University; Hangzhou First People's Hospital affiliated to Zhejiang University, Bethune Charitable Foundation | Colorectal disease | | | | |
ChiCTR2100053316: Randomized double-blind controlled study of different antiemetic drugs in gynecological day surgery with remimazolam and alfentanil |
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| Recruiting | 4 | 150 | | Dexamethasone and Tropisetron ;Dexamethasone and Droperidol ;Dexamethasone | Weifang People's Hospital; Weifang People's Hospital, Self-funded | Postoperative nausea and vomiting (PONV) | | | | |
ChiCTR2200055994: Effects of remimazolam combined with visual double-lumen bronchial catheter technique on oxidative stress and postoperative complications in patients with thoracic surgery |
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| Recruiting | 4 | 31 | | test group | The General Hospital of Western Theater Command; The General Hospital of Western Theater Command, Hospital management issues of the General Hospital of Western Theater Command in 2021 | stress response | | | | |
ChiCTR2100050181: A prospective randomized controlled trial of the efficacy and safety of remimazolam besylate in fiberoptic bronchoscopy in the ICU |
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| Not yet recruiting | 4 | 30 | | The initial dose of Remimazolam besylate was 5mg, and the additional dose was 2.5mg/ time ;The initial dose of propofol was 1.5mg/kg, and the additional dose was 0.5mg/kg/ time | The Third Affiliated Hospital, Sun Yat-sen University; The Third Affiliated Hospital, Sun Yat-sen University, self-raised | ICU sedation | | | | |
ChiCTR2200057446: Dose-effect relationship of rimaazulene mesylate used in adult gastroscopy |
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| Not yet recruiting | 4 | 25 | | Injection of remimazolam | Zhuji People ' s Hospital; Zhuji People ' s Hospita, raise independently | painless gastroscopy | | | | |
ChiCTR2100053118: Clinical study on the diffenrence in blood pressure between remimazolam and etomidate during anesthesia induction |
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| Completed | 4 | 138 | | Etomidate ;Remimazolam | The First Affiliated Hospital of Guangxi Medical University; The First Affiliated Hospital of Guangxi Medical University, This study was supported by the Traditional Chinese medicine appropriate technology development and promotion project of Guangxi , the Natural Science Foundation of Guangxi | Anesthesiology | | | | |
ChiCTR2200056092: Effect of remimazolam or propofol sedation on the quality of recovery after colonoscopy |
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| Not yet recruiting | 4 | 248 | | Fentanyl 1ug/kg was administered to patients by intravenous injection before the assigned trial sedatives.Give the initial dose of 5.0 mg of remimazolam. If sufficient sedation is not obtained, inject supplementary doses of remimazolam (2.5 mg per dose), and the supplement interval must be more than 1 minute. ;Fentanyl 1ug/kg was administered to patients by intravenous injection before the assigned trial sedatives.An initial dose of 1.5 mg/kg of propofol is given. If sufficient sedation is not obtained, a supplementary dose of propofol (1.5 mg/kg each time) is injected. | Affiliated Hospital of Xuzhou Medical University; Affiliated Hospital of Xuzhou Medical University, Self-funded | Colonoscopy | | | | |
NCT04919174: A Randomized Single-blind Clinical Trial of the Efficacy and Safety of Remimazolam in Painless Bronchoscopy |
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| Recruiting | 4 | 364 | RoW | Remimazolam, Remifentanil, Dexmedetomidine | Second Affiliated Hospital, School of Medicine, Zhejiang University | Bronchoscopy, Sedation | 04/22 | 10/22 | | |
ChiCTR2100044177: Safety and efficacy of remimazolam besylate combined with alfentanil hydrochloride in hysteroscopy |
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| Recruiting | 4 | 120 | | Remimazolam + alfentanil ;Remimazolam + remifentanil | Mengcheng County No.1 People's Hospital; Mengcheng County No.1 People's Hospital, Self-financing | Abnormal uterine bleeding | | | | |
ChiCTR2100053906: The effect of remimazolam on postoperative sleep quality in patients undergoing gynecological laparoscopic surgery |
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| Completed | 4 | 120 | | Induction and maintenance of remimazolam; Induction and maintenance of propofol | The First Affiliated Hospital of Zhengzhou University; The First Affiliated Hospital of Zhengzhou University, self-funded | N/A | | | | |
ChiCTR2100054101: Comparison of the spectral features of the frontal electroencephalogram in patients receiving remimazolam besilate and propofol total intravenous general anesthesia |
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| Not yet recruiting | 4 | 50 | | patients received propofol general anesthesia ;patients received remimazolam general anesthesia | The First Affiliated Hospital of Anhui Medical University; Department of Anesthesiology, the First Affiliated Hospital of Anhui Medical University, Self-funded | Hip surgery | | | | |
ChiCTR2100045491: The comparison of hemodynamic effects in the anesthesia induction between remimazolam and midazolam for elderly patients underwent non-cardiac surgery: a prospective, random, control study |
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| Recruiting | 4 | 200 | | Remimazolam 0. 05 mg /kg i.v. ;Midazolam 0. 05 mg /kg i.v. | Third Affiliated Hospital of Sun Yat-Sen University; Third Affiliated Hospital of Sun Yat-Sen University, Raised by researchers | Hemodynamic fluctuation during induction of general anesthesia | | | | |
ChiCTR2100047794: Clinical study on efficacy and safety of different dose remimazolam in elderly patients during general anesthesia induction |
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| Not yet recruiting | 4 | 200 | | remimazolam and propofol | Linfen Central Hospital; Linfen Central Hospital, Beijing RongHe Medical Development Foundation. | General Anesthesia | | | | |
ChiCTR2100046745: Clinical effect observation of remimazolam combined with alfentanil in patients undergoing painless gastrointestinal endoscopy |
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| Recruiting | 4 | 360 | | Alfentanil 7μg/kg intravenously, followed by a slow injection of propofol 1.5mg/kg ;Alfentanil 7μg/kg was injected intravenously during the induction period, followed by intravenous injection of remimazolam 0.1 mg/kg ;Alfentanil 7μg/kg was injected intravenously during the induction period, followed by intravenous injection of remimazolam 0.2 mg/kg ;Alfentanil 7μg/kg was injected intravenously during the induction period, followed by intravenous injection of remimazolam 0.3 mg/kg | The Affiliated Hospital of Xuzhou Medical University; The Affiliated Hospital of Xuzhou Medical University, Yichang Humanwell Pharmaceutical Co., Ltd. | N/A | | | | |
ChiCTR2000033871: Clinical study for the efficacy and safety of remimazolam applied in slow endotracheal intubation under Spontaneous Breathing for obstructive sleep apnea syndrome |
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| Not yet recruiting | 4 | 54 | | topical anesthesia + remifentanil ;topical anesthesia + remifentanil + midazolam ;topical anesthesia + remifentanil + ramidazolam | Chancheng District Central Hospital, Foshan, China; Chancheng District Central Hospital, Foshan, China, Guangdong Provincial Hospital Pharmaceutical Research Fund (Xinchen Comfortable Medical Special Fund) | obstructive sleep apnea syndrome | | | | |
ChiCTR2000034677: Effect of Remimazolam(CNS 7056) on postoperative cognitive dysfunction after partial hepatectomy in elderly patients |
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| Recruiting | 4 | 120 | | Group R was given remimazolam mesylate 6mg / kg / h for 5min before anesthesia induction. ;Midazolam 0.04 mg / kg was given at the beginning of anesthesia induction | Department of Anesthesiology, Mianyang Central Hospital; Mianyang Central Hospital, Sichuan International Medical Exchange Promotion Association | Postoperative cognitive dysfunction | | | | |
ChiCTR2000038976: Effect of Remimazolam Besylate combined with Sufentanil on the incidence of delirium in patients after cardiac surgery |
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| Recruiting | 4 | 100 | | Remimazolam Besylate combined with Sufentanil ;Propofol combined with Sufentanil | Liaocheng Cardiac Hospital; Liaocheng Cardiac Hospital, None | Postcardiac surgery | | | | |
ChiCTR2100046214: Remimazolam vs Propofol for Sedation in ICU Patients with Mechanical Ventilation |
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| Recruiting | 4 | 90 | | Remimazolam ;propofol | Affiliated Hospital of Guizhou Medical University; Affiliated Hospital of Guizhou Medical University, Beijing Fusion Fund | Critically ill | | | | |
ChiCTR2100046928: Safety and efficacy of remimazolam sedation and propofol sedation in patients undergoing colonoscopic polypectomy |
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| Not yet recruiting | 4 | 120 | | Propofol ;Remimazolam | Liaocheng People's Hospital; Liaocheng People's Hospital, None | Colonic polyps | | | | |
ChiCTR2100047957: Effect of remimazolam on peri-operative stress response and immune function |
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| Not yet recruiting | 4 | 60 | | Propofol as the exclusive sedative ;Remimazolam as the exclusive sedative | Yixing People's Hospital; Yixing People's Hospital, self-funded | N/A | | | | |
ChiCTR2100048242: The safety and efficacy of remimazolam as a potential anesthesia induction agent during endotracheal intubation in spontaneous breathing patients |
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| Not yet recruiting | 4 | 210 | | Sevoflurane anesthesia induction ;Remazolam anesthesia induction | Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University; Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, 2020 Guangdong Provincial Hospital Pharmacy Research Fund | N/A | | | | |
ChiCTR2100053014: Comparing remimazolam with propofol on postoperative quality of recovery in patients undergoing ambulatory arthroscopic surgery |
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| Recruiting | 4 | 120 | | Induction and maintenance of remazolam anesthesia ;Induction and maintenance of propofol anesthesia | The First Affiliated Hospital of Anhui Medical Univercity; Department of Anesthesiology, the First Affiliated Hospital of Anhui Medical University, Self-funded | Knee joint disease | | | | |
ChiCTR2200057653: Half-effective Dose of Remimazolam Toislate in Combination with Alfentanil to Inhibit the Response to Painless Gastroscopy Placement in Elderly Patients |
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| Not yet recruiting | 4 | 90 | | Male only ;Female only ;Gender is not limited | The Second Hospital of Jiaxing; The Second Hospital of Jiaxing, Self-financing | Painless Gastroscopy | | | | |
| Not yet recruiting | 4 | | | | Anhui Second People's Hospital; Anhui Second People's Hospital, self-raised | Sedation during painless gastroscop | | | | |
ChiCTR2200060474: Effects of different sedatives (remimazolam/propofol) on hemodynamics during gastrointestinal endoscopy in the elderly |
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| Not yet recruiting | 4 | 80 | | remimazolam ;propofol | Department of Anesthesiology, Shanghai Yangpu District Shidong Hospital; Shanghai Yangpu District Shidong Hospital, PhD Research Startup Fund | N/A | | | | |
ChiCTR2100045420: Comparison of clinical efficacy of remazolam and propofol in patients with acute stroke after endovascular treatment |
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| Recruiting | 4 | 120 | | Remimazolam ;Propofol | Xiangtan Central Hospital; Xiangtan Central Hospital, Self-funded | Acute stroke | | | | |
ChiCTR2100046742: Effect of remimazolam combined with propofol on EEG and postoperative delirium in elderly patients |
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| Recruiting | 4 | 180 | | midazolam ;0.05mg/kg remimazolam ;0.1mg/kg remimazolam | The Second Hospital of Tianjin Medical University; The Second Hospital of Tianjin Medical University, Zhongguancun Precision Medicine Foundation | Postoperative delirium | | | | |
ChiCTR2100049786: Safety and effectiveness of remimazolam combined with Butorphanol in hysteroscopy |
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| Not yet recruiting | 4 | 90 | | Propofol ;Propofol+Butorphanol ;remimazolam+Butorphanol | Jingmen First People's Hospital; Jingmen First People's Hospital, Ewan Research Fund | Hysteroscopic surgery | | | | |
ChiCTR2100054053: The efficacy and safety of remimazolam in colonoscopy patients: a prospective, randomized clinical trial |
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| Not yet recruiting | 4 | 300 | | 0.15 mg / kg remimazolam and 0.04 mg / kg as required ;0.2 mg / kg remimazolam and 0.04 mg / kg as required ;2 mg / kg propofol and 0.4 mg / kg as required | Shanghai East Hospital; Shanghai East Hospital, National Natural Science Foundation Project | Painless Enteroscopy | | | | |
ChiCTR2200057416: Safety and efficacy of remimazolam combined with nalbuphine for patients in enhanced recovery after painless hysteroscopy |
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| Not yet recruiting | 4 | 150 | | propofol ;remimazolam ;remimazolam | The First Affiliated Hospital of Anhui Medical Univercity; Department of Anesthesiology, the First Affiliated Hospital of Anhui Medical University, the Joint Project of Anesthesiology and Pharmacology of the First Affiliated Hospital of Anhui Medical Univercity | Intravenous anesthesia in hysteroscopic examination or operation | | | | |
NCT05429086: Explore the Advantages of Remimazolam Used on Gastroscopy |
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| Not yet recruiting | 4 | 287 | NA | Remimazolam combined propofol, Remimazolam, Propofol | Sichuan Provincial People's Hospital | Induction of Anesthesia | 08/22 | 08/22 | | |
NCT05480787: Pharmacokinetic Study of Continuous Infusion of Remazolam in Mechanically Ventilated Patients in ICU |
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| Active, not recruiting | 4 | 30 | RoW | Remimazolam 0.1mg/kg/h, Remimazolam 0.3mg/kg/h, Remimazolam 0.5mg/kg/h | The First Affiliated Hospital with Nanjing Medical University | Intensive Care Unit, Mechanical Ventilation, Anesthesia, Liver Failure, Pharmacokinetics | 08/22 | 09/22 | | |
ChiCTR2100050372: Effect of remimazolam on postoperative delirium in elderly patients |
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| Recruiting | 4 | 360 | | remimazolam ;propofol | The First Affiliated Hospital of Zhengzhou University; The First Affiliated Hospital of Zhengzhou University, Self-raised | Postoperative delirium | | | | |
ChiCTR2100045313: Comparative study on efficacy and safety of Remimazolam toluene sulfonate and dexmedetomidine in patients with severe neurologic disease |
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| Recruiting | 4 | 180 | | Rimazolam (load dose 0.2mg/kg, maintenance dose 0.1mg/kg/h~0.45mg/kg/h) ;Dexmedetomidine (loading dose 1ug/kg, maintenance dose 0.2-0.7ug /kg/h) | Neurosurgery of Zhangjiajie City People's Hospital; Zhangjiajie City People's Hospital, China Health Promotion Foundation | severe neurologic disease | | | | |
ChiCTR2100049351: Study on the Safety and Efficacy of Different Doses of Esketamine Combined with Remimazolam Toluene Sulfonate in Painless Bronchoscopy |
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| Not yet recruiting | 4 | 150 | | esketamine (0.1mg/ kg) ;placebo ;esketamine (0.2mg/ kg) ;esketamine (0.3mg/ kg) ;esketamine (0.4mg/ kg) | Shandong Provincial ENT Hospital (Shandong Provincial Western Hospital); Shandong Provincial ENT Hospital (Shandong Provincial Western Hospital), self-financed | bronchoscopy | | | | |
| Recruiting | 4 | 150 | | remimazolam (ED50 dose, dose determined by part I test) ;remimazolam (ED95 dose, dose determined by part II test) ;dexmedetomidine(1 μg/㎏) | Guangxi Medical University College of Stomatology; Guangxi Medical University College of Stomatology, Department of Anesthesiology, Affiliated Stomatological Hospital of Guangxi Medical University | Difficult Airway | | | | |
ChiCTR2200059697: Effect of remimazolam and propofol on left heart function during induction of general anesthesia in elderly patients |
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| Not yet recruiting | 4 | 60 | | Intravenous infusion of propofol; Intravenous infusion of remimazolam | Jiangsu Province Hospital; Jiangsu Province Hospital, self-finance | elderly patients | | | | |
ChiCTR2200055233: Effect of remimazolam combined with dexmedetomidine in the treatment of emergence agitation in adult patients |
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| Recruiting | 4 | 60 | | Nil ;Nil | The First Affiliated Hospital of Zhengzhou University; The First Affiliated Hospital of Zhengzhou University, None | N/A | | | | |
ChiCTR2200062413: Comparative analysis of BIS correlation index in sedation between remimazolam and propofol |
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| Not yet recruiting | 4 | 30 | | Alfentanil 10μg/kg+propofol 2mg/kg ;Alfentanil 10μg/kg+remimazolam 0.15mg/kg | Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology; Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Raise independently | Colonic polyps | | | | |
| Not yet recruiting | 4 | 55 | | Intravenous injection of different doses of rimimazolam | Zhuji People ' s Hospital; Zhuji People ' s Hospital, self-finance | painless gastroscopy | | | | |
NCT05554965: Endoscopic Hemostatic and Sedative Treatment of Esophageal and Gastric Variceal Bleeding |
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| Recruiting | 4 | 60 | RoW | Propofol, Active Comparator, Remimazolam besylate, Experimental | Renmin Hospital of Wuhan University | Endoscopic Hemostasis, Sedation | 10/22 | 12/22 | | |
ChiCTR2100052435: The effects of remimazolam verus dexmedetomidine on short-term postoperative sleep quality in elderly patients undergoing ERCP |
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| Not yet recruiting | 4 | 120 | | saline ;remimazolam | Liaocheng People's Hospital; Liaocheng People's Hospital, Comfortable Medical Care of Shandong Medical Association - Special Fund for Anesthesia Optimization | endoscopic retrograde cholangiopancreatography | | | | |
ChiCTR2400083937: To compare the sedative effect of Remimazolam Besylate for injection with propofol by Bispectral index |
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| Completed | 4 | 46 | | Start sedation and analgesia with a combination of 0.25-0.1ug/kg/h remifentanil besylate and 6-9ug/kg/h remifentanil.; Use a combination of 0.5-4mg/kg/h propofol and 6-9ug/kg/h remifentanil to start sedation and analgesia. | The First Hospital affiliated to ZheJiang University School of Medicine.; The First Hospital affiliated to ZheJiang University School of Medicine., China International Medicine Foundation | patients accepted sedation in ICU | | | | |
NCT05041725: The Impact of Remimazolam for Postoperative Sedation on the Left Ventricular Systolic Performance in Cardiac Surgery |
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| Not yet recruiting | 4 | 15 | NA | Remimazolam Injection [Byfavo], Remimazolam infusion | Konkuk University Medical Center | Coronary Artery Disease | 11/22 | 12/22 | | |
ChiCTR2100042310: Application of Rebazolam benzenesulfonic acid in sedation during off-pump coronary artery bypass grafting |
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| Recruiting | 4 | 68 | | The anesthesia was induced with 0.2mg/kg remimazolam besylate ;The anesthesia was induced with 0.3mg/kg remimazolam besylate ;The anesthesia was induced with 0.4mg/kg remimazolam besylate ;The anesthesia was induced with 0.1mg/kg midazolam | Beijing Anzhen Hospital Affiliated to Capital Medical University; Beijing Anzhen Hospital Affiliated to Capital Medical University, Bethune Charitable Foundation | Off-pump Coronary Artery Bypass Grafting | | | | |
ChiCTR2100054129: Application of remimazolam besylate in painless gastrointestinal endoscopy in elderly patients |
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| Not yet recruiting | 4 | 406 | | Sufentanil 0.1ug/kg+ remimazolam 7mg ;Sufentanil 0.1ug/kg+ propofol 1.5mg/kg | Shanghai East Hospital (Affiliated East Hospital of Tongji University); Shanghai East Hospital (Affiliated East Hospital of Tongji University), Bethune Charitable Foundation | Gastrointestinal diseases | | | | |
ChiCTR2200062668: Effect of sufentanil on laryngeal mask placement ED50 and ED95 induced by remimazolam general anesthesia |
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| Not yet recruiting | 4 | 80 | | induced by remimazolam general anesthesia ;induced by sufentanil and remimazolalm | Zhuji People's Hospital; Zhuji People's Hospital, self-funded | general anesthesia | | | | |
ChiCTR2100041690: Application of different doses of remimazolam besylate in hysteroscopic surgery |
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| Recruiting | 4 | 476 | | The initial loading dose of remimazolam besylate was 7mg ;The initial loading dose of remimazolam besylate was 9.5mg ;The initial loading dose of remimazolam besylate was 12mg ;The initial loading dose of remimazolam besylate was 14.5mg | Shenzhen Maternity and Child Healthcare Hospital; Shenzhen Maternity and Child Healthcare Hospital, Bethune Charitable Foundation | hysteroscopy | | | | |
ChiCTR2100041805: Clinical study of preemptive sedation with remimazolam on prevention of propofol injection pain in induced abortion / curettage patients |
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| Recruiting | 4 | 210 | | NS ;Lidocaine ;Reminazolam | The First Affiliated Hospital of Guangxi Medical University; The First Affiliated Hospital of Guangxi Medical University, None | Pain | | | | |
ChiCTR2100042917: Remimazolam combined with remifentanil for moderate sedation in awake fiberoptic intubation |
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| Recruiting | 4 | 150 | | Infusion of remifentanil; Combined infusion of remifentanil and remimazolam; Combined infusion of remifentanil and remimazolam; Combined infusion of remifentanil and remimazolam; Infusion of remimazolam | Beijing Friendship Hospital, Capital Medical University; Beijing Friendship Hospital, Capital Medical University, Bethune Foundation | Airway management | | | | |
ChiCTR2100045851: Clinical Application of Different Sedatives in Intrahospital Transports to Diagnostic Tests of ICU Artificial Airway Patients |
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| Recruiting | 4 | 240 | | Remimazolam ;Midazolam ;Propofol | The Second Affiliated Hospital of Harbin Medical University; The Second Affiliated Hospital of Harbin Medical University, China International Medical Foundation | Critically disease | | | | |
NCT04861337: Remimazolam and Postoperative Nausea and Vomiting in High-risk Patients |
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| Completed | 4 | 552 | RoW | Remimazolam, Remimazolam group, Placebo, Placebo group | Peking University First Hospital | Postoperative Nausea and Vomiting, Benzodiazepine, High-risk Patients | 12/22 | 04/23 | | |
ChiCTR2100046492: Sedative effect of remimazolam combined with alfentanil in colonoscopic polypectomy |
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| Not yet recruiting | 4 | 120 | | I.V. Alfentanil 10μg/kg+ remimazolam 0.1mg/kg ;I.V. Alfentanil 10μg/kg+ remimazolam 0.15mg/kg ;I.V. Alfentanil 10μg/kg+ remimazolam 0.2mg/kg ;I.V. Alfentanil 10μg/kg+ Propofol 2mg/kg | Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of science and technology; Tongji Hospital, raise independently | Colonic polyps | | | | |
ChiCTR2100049951: Efficacy and safety of remimazolam besylate in the obese patients during colonoscopy |
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| Not yet recruiting | 4 | 82 | | propofol for sedation ;remimazolam for sedation | The First Affiliated Hospital of Zhengzhou University; The First Affiliated Hospital of Zhengzhou University, self-funded | none | | | | |
ChiCTR2100050300: Comparison of efficacy of remimazolam and propofol on induction and maintenance of anesthesia in elderly patients undergoing ureteroscopic laser lithotripsy |
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| Recruiting | 4 | 80 | | Remazolam is a combination of intravenous anesthesia ;Propofol was anesthetized by intravenous combination | The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University; The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, self-raised | urolithiasis | | | | |
ChiCTR2100054347: ED50 and safety of remimazolam combined with nalbuphine during painless gastroscopy in elderly patients |
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| Completed | 4 | 27 | | Nalbuphine 0.1mg/kg | The First Affiliated Hospital of Anhui Medical Univercity; The First Affiliated Hospital of Anhui Medical Univercity, self-financed | Digestive system diseases | | | | |
ChiCTR2200057106: Median effective dose of esketamine combined with remimazolam used in painless hysteroscopic day surgery for adults |
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| Not yet recruiting | 4 | 100 | | Esketamine ;Remimazolam | Hainan General Hospital; Hainan General Hospital, Self-funded | Painless hysteroscopic | | | | |
ChiCTR2200061051: Effect of remimazolam on induction and maintenance of general anesthesia in patients undergoing renal transplantation |
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| Not yet recruiting | 4 | 100 | | Propofol ;Remimazolam replaces Propofol | Department of Anesthesiology, the Second Affiliated Hospital of Guangxi Medical University; The Second Affiliated Hospital of Guangxi Medical University, self-funded | End stage renal disease | | | | |
ChiCTR2200062835: Study on 90% effective dose of remimazolam combined with alfentanyl in adult colonoscopy |
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| Not yet recruiting | 4 | 55 | | Intravenous injection of different doses of rimaazolam | Traditional Chinese Medical Hospital of Zhuji; Zhuji Hospital of Traditional Chinese Medicine, self-funded | painless colonoscopy | | | | |
ChiCTR2200063275: Effect of intravenous lidocaine on the ED50 of remimazolam induction dose during laryngeal mask airway insertion in adult patients |
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| Not yet recruiting | 4 | 50 | | Lidocaine intravenous ;Same volume normal saline intravenous | The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University; The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, self-raised | Laryngeal mask for general anesthesia | | | | |
ChiCTR2200064049: Application of remimazolam in patients undergoing radical resection of esophageal cancer under general anesthesia |
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| Not yet recruiting | 4 | 60 | | Sedation under general anesthesia was done by intravenous propofol ;Sedation under general anesthesia was done by intravenous remimazolam | Affiliated Cancer Hospital of Zhengzhou University; Affiliated Cancer Hospital of Zhengzhou University, 2020 Medical Science and Technology Project of Henan Province | Esophageal cancer | | | | |
ChiCTR2200064374: Effect of ciprofol and remimazolam on early postoperative quality of recovery in gynecologic laparoscopic surgery patients |
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| Not yet recruiting | 4 | 90 | | ciprofol ;remimazolam ;propofol | The First Affiliated Hospital of Zhengzhou University; The First Affiliated Hospital of Zhengzhou University, self-funded | Comparison of effects of intravenous anesthetic drugs | | | | |
ChiCTR2200064885: Half effective-site concentration of remifentanil combined with remimazolam besylate in hysteroscopy |
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| Not yet recruiting | 4 | 50 | | Pump remifentanil | Mengcheng County No. 1 People's Hospital; Mengcheng County No. 1 People's Hospital, Self-funded | Abnormal uterine bleeding | | | | |
ChiCTR2200066502: Effect of remimazolam versus propofol on the ventilation of patients undergoing bronchoscopy |
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| Recruiting | 4 | 80 | | remimazolam ;propofol | Suzhou Dushu Lake Hospital (Dushu Lake Hospital Affiliated to Soochow University); Suzhou Dushu Lake Hospital (Dushu Lake Hospital Affiliated to Soochow University), Special Fund by Anesthesiology Reaserch, Jiangsu Province Medical Association | respiratory disease | | | | |
ChiCTR2200063276: Study of hypotension during induction of anesthesia with remimazolam besylate for injection in elderly patients undergoing painless fibrinoscopy |
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| Not yet recruiting | 4 | 224 | | Remazolam besylate for injection ;Propofol | Sichuan Academy of Medical Sciences·Sichuan Provincial People's Hospital; Sichuan Academy of Medical Sciences·Sichuan Provincial People's Hospital, Academic Construction Funds | Respiratory diseases | | | | |
ChiCTR2200056115: Effects of different doses of remimazolam on bispectral index and hemodynamics of induced by daytime general anesthesia: A randomized controlled trial |
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| Not yet recruiting | 4 | 90 | | Remimazolam was pumped 6 mg/kg/h during induction of anesthesia ;Remimazolam was pumped 9 mg/kg/h during induction of anesthesia ;Remimazolam was pumped 12 mg/kg/h during induction of anesthesia | Department of Anesthesiology, the First Affiliated Hospital of Anhui Medical University; the First Affiliated Hospital of Anhui Medical University, Anhui key project of outstanding young talents in colleges and universities (gxyqZD2018028) | Narcotic sedative drug | | | | |
ChiCTR2200057555: ED50 of remimazolam combined with nalbuphine in painless hysteroscopy |
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| Not yet recruiting | 4 | 100 | | Nalbuphine 0.1mg/kg ;Nalbuphine 0.15mg/kg | The First Affiliated Hospital of Anhui Medical University; The First Affiliated Hospital of Anhui Medical University, Self-financing | painless hysteroscopy | | | | |
NCT06513923: Comparison of Remimazolam and Propofol on Emergence in Elderly Orthopedic Patients Under General Anesthesia |
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| Completed | 4 | 136 | RoW | Remimazolam, Flumazenil, Propofol | Central South University | Hip Fracture | 09/23 | 10/23 | | |
ChiCTR2200056641: An exploratory study on the applied dose of remimazolam during the induction of general anesthesia |
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| Recruiting | 4 | 60 | | receive remimazolam via infusion based on TBW ;receive remimazolam via infusion based on LBW ;receive remimazolam via infusion based on TBW | Eye & ENT Hospital of Fudan University; Eye & ENT Hospital of Fudan University, Self raised by researchers. | effective induction dose in obese population | | | | |
