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32 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Vtama (tapinarof) / Organon
ChiCTR2000032348: A multi-center randomized controlled clinical research in Guangxi to evaluate the efficacy and the safety of topically applied benvitimod cream in patients with plaque psoriasis

Recruiting
4
50
 
1-2W: Halometasone Cream, qd, am; Benvimod Cream, qd, pm; 3-4W: Benvimod Cream, bid, Monday to Friday; Halometasone Cream, bid, Saturday and Sunday; 5-8W: Benvimod Cream, bid. ;1-2W: Halometasone Cream, qd, am; Calcipotriol Ointment, qd, pm; 3-4W: Calcipotriol Ointment, bid, Monday to Friday; Halometasone Cream, bid, Saturday and Sunday; 5-8W: Calcipotriol Ointment, bid.
The Third Affiliated Hospital of Guangxi Medical University; The Third Affiliated Hospital of Guangxi Medical University, Company grants
plaque psoriasis
 
 
ChiCTR2100046872: A study of tapinarof for the treatment of localized scleroderma

Recruiting
4
20
 
Topical benvimod drugs
The Second Xiangya Hospital of Central South University; The Second Xiangya Hospital of Central South University, Self-raised
Localized scleroderma
 
 
NCT05680740: A Study to Investigate Efficacy and Safety of VTAMA (Tapinarof) Cream, 1% in Intertriginous Plaque Psoriasis

Completed
4
34
US
VTAMA® (tapinarof) Cream 1%, DMVT-505
Dermavant Sciences, Inc.
Psoriasis
05/23
05/23
NCT05789576: A Study to Investigate Efficacy and Safety of VTAMA® (Tapinarof) Cream, 1% in Plaque Psoriasis in the Head and Neck Region

Completed
4
31
US
VTAMA (tapinarof) cream, 1%, DMVT-505
Dermavant Sciences, Inc.
Psoriasis
06/23
07/23
ChiCTR2200059396: Efficacy and Safety of Benvitimod Cream in the Retreatment of Mild to Moderate Psoriasis

Not yet recruiting
4
390
 
Benvitimod Cream ;Vertical
Peking University People's Hospital; Guangdong Zhonghao Pharmaceutical Co., Ltd., Guangdong Zhonghao Pharmaceutical Co., Ltd.
Psoriasis
 
 
ChiCTR2100050043: A phase IV clinical trial of Benvitimod to treat mild-to-moderate psoriasis of adults

Not yet recruiting
4
2000
 
external use
Peking University People's Hospital; Level of the institution：, Sponsor
Psoriasis
 
 
NCT06103695: Vtama in Psoriasis Patients Being Treated With Biologics.

Completed
4
30
US
Tapinarof
Psoriasis Treatment Center of Central New Jersey
Psoriasis
10/23
10/23
ChiCTR2000041261: An observational real world study of benvitimod cream in the treatment of psoriasis

Recruiting
4
10000
 
benvitimod cream
Beijing Yuanxin Technology Group Co. LTD; Guangdong Zhonghao Pharmaceutical Co. Ltd., Self-funded
psoriasis
 
 
NCT05064748: Phase IV Clinical Study of Benvitimod Cream in the Treatment of Mild to Moderate Psoriasis in Adults

Recruiting
4
2000
RoW
Benvitimod
Peking University People's Hospital, Zhonghao Pharmaceutical
Psoriasis
03/24
09/24
ChiCTR2100051898: Phase IV Clinical Study of Benvitimod Cream in the Treatment of Mild to Moderate Psoriasis in Adults

Recruiting
4
2000
 
Benvitimod Cream
Peking University People's Hospital; Peking University People's Hospital, Guangdong Zhonghao Pharmaceutical Co., Ltd.
Psoriasis
 
 
ChiCTR2500096856: Real world study of Benvitimod cream in the treatment of chronic simple lichen

Recruiting
4
80
 
NA; NA
Taizhou Central Hospital; Taizhou Central Hospital, Guangdong Zhonghao Pharmaceutical Co., LTD
Chronic simple lichen
 
 
ChiCTR2400085598: A prospective randomized controlled study of Benvermod combined with IL-17 monoclonal antibody in the treatment of refractory lesions of the lower leg in patients with moderate-to-severe plaque psoriasis

Not yet recruiting
4
60
 
Benvitimod cream; Benvitimod Vehicle cream
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine; Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Guangdong Zhonghao Pharmaceutical Co., LTD
Patients with moderate-to-severe plaque psoriasis have intractable lesions of the lower leg
 
 
ChiCTR2500098254: A Multicenter Study on the Impact of Long-Term and Proactive Intermittent Maintenance Treatment with Benvitimod on Psoriasis Recurrence

Not yet recruiting
4
120
 
Apply 1% Benvitimod cream topically to the lesions twice daily (morning and evening) for 12 consecutive weeks; Apply 1% Benvitimod cream twice weekly for 12 weeks; Apply the vehicle cream twice weekly for 12 weeks
Peking University Third Hospital; Peking University Third Hospital, All funding for this research project was provided by Chongqing Zhixiang Jintai Biopharmaceutical Co., Ltd.
Psoriasis
 
 
ChiCTR-TRC-13003259: Multi-centre, randomised, double-blind, placebo- and comparator-controlled trial on topically applied benvitimod cream in patients with psoriasis

Completed
3
720
 
1.0% Benvitimod cream ;Placebo ;Calcipotrione Ointment
People's Hospital of Peking University; Celestial Pharmaceutical (Shenzhen) co., Ltd., Beijing Wenfeng Tianji Pharmaceutical Technology Co., Ltd.
Plaque psoriasis
 
 
NCT05032859: Tapinarof for the Treatment of Atopic Dermatitis in Children and Adults (DMVT-505-3102)

Completed
3
406
Canada, US
tapinarof cream, 1%, vehicle cream
Dermavant Sciences, Inc.
Atopic Dermatitis
02/23
02/23
NCT05014568: Tapinarof for the Treatment of Atopic Dermatitis in Children and Adults

Completed
3
407
Canada, US
tapinarof cream, 1%, Vehicle cream
Dermavant Sciences, Inc.
Atopic Dermatitis
03/23
04/23
NCT05326672: Phase III Clinical Study of Benvitimod Cream in the Treatment of Mild to Moderate Atopic Dermatitis

Recruiting
3
240
RoW
Benvitimod Cream, Placebo
Peking University People's Hospital, Zhonghao Pharmaceutical
Atopic Dermatitis
06/23
12/23
ChiCTR2200059419: Phase III Clinical Study of Benvitimod Cream in the Treatment of Mild to Moderate Atopic Dermatitis

Not yet recruiting
3
240
 
Benvitimod Cream ;Placebo
Peking University People's Hospital; Guangdong Zhonghao Pharmaceutical Co., Ltd., Guangdong Zhonghao Pharmaceutical Co., Ltd.
Atopic Dermatitis
 
 
NCT05142774: Long Term Extension Study of Tapinarof Cream, 1% for Subjects With Atopic Dermatitis

Completed
3
728
Canada, US
Tapinarof cream, 1%
Dermavant Sciences, Inc.
Atopic Dermatitis
02/24
03/24
NCT06742957: Study Comparing Tapinarof Cream 1% to VTAMA ® (Tapinarof Cream 1%) in the Treatment of Plaque Psoriasis

Recruiting
3
560
US
Tapinarof Cream 1%, VTAMA®, Placebo
Teva Pharmaceuticals USA, Teva Pharmaceuticals, Inc.
Plaque Type Psorisis
10/25
11/25
NCT05172726: Tapinarof for the Treatment of Plaque Psoriasis in Pediatric Subjects

Recruiting
3
100
Canada, US
tapinarof cream, 1%
Dermavant Sciences, Inc.
Plaque Psoriasis
09/26
09/26
NCT05981118: Comparison of Post-Inflammatory Pigment Alteration After Psoriasis Treatment (PIPA - Dermavant)

Enrolling by invitation
2/3
40
US
Betamethasone dipropionate 0.05%, Tapinarof
Wake Forest University Health Sciences, Dermavant Sciences, Inc.
ICD10 Code L40.9 for Psoriasis
07/25
12/25
ChiCTR-IIR-17012153: Multi-centre, randomised, double-blind, placebo- and comparator-controlled trial on benvitimod cream in patients with Atopic Dermatitis

Recruiting
2
120
 
0.5% Benvitimod cream ;1.0% Benvitimod cream ;Placebo ;Tacrolimus
Peking University People's Hospital; Beijing Wenfeng Tianji Pharmaceuticals Co., Ltd., Beijing Wenfeng Tianji Pharmaceuticals Co.,Ltd.
Atopic Dermatitis
 
 
NCT06561321: Study to Evaluate the Safety and Efficacy of Tapinarof in Adults With Palmoplantar Keratoderma

Recruiting
2
6
US
Tapinarof
Indiana University, Dermavant Sciences, Inc.
Palmoplantar Keratoderma
02/26
11/26
ChiCTR-TRC-10000995: Pharmacokinetics and Tolerability of Topically Applied Benvitimod Cream in Patients with Psoriasis

Completed
1/2
36
 
0.5% Benvitimod cream ;1.0% Benvitimod cream ;1.5% Benvitimod cream
People's hospital, Peking University; Celestial Pharmaceutical(Shenzhen) co., Ltd., Celestial Pharmaceutical(Shenzhen) co.,Ltd.
Plaque Psoriasis
 
 
ChiCTR-TRC-11001391: Multicentre, randomised, double-blind, placebo controlled trial on topically applied benvitimod cream in patients with psoriasis

Completed
1/2
360
 
0.5% Benvitimod cream ;1.0% Benvitimod cream ;1.0% Benvitimod cream
People's Hospital of Peking University; Celestial Pharmaceutical(Shenzhen) co., Ltd, Celestial Pharmaceutical (Shenzhen) co.,Ltd.
Plaque psoriasis
 
 
ChiCTR1900026921: Study for preliminary efficacy/safety and pharmacokinetics of benvitimod cream in the treatment by systemic exposure of Atopic Dermatitis

Completed
1
6
 
Two times a day for 20 consecutive days
Peking University People's Hospital; Beijing Wenfeng Tianji Pharmaceuticals Co., Ltd., Beijing Wenfeng Tianji Pharmaceuticals Co.,Ltd.
Atopic Dermatitis
 
 
NCT06661213: Tapinarof for Cutaneous Lupus Erythematosus

Not yet recruiting
1
10
US
Tapinarof, VTAMA
Northwestern University
Cutaneous Lupus Erythematosus
03/26
03/26
ChiCTR2100043864: A real world study of Benvimod cream in the treatment of atopic dermatitis and eczema

Completed
N/A
40
 
Benvitimod cream
The First Center Hospital of Tianjin; Hao in Guangdong Pharmaceutical Industries, ltd, Hao in Guangdong Pharmaceutical Industries, ltd
Atopic Dermatitis and Eczema
 
 
ChiCTR2100043862: A real world study for Benvitimod cream in the treatment of Palmoplantar pustulosis

Completed
N/A
48
 
palmar and plantar pustulosis
The First Center Hospital of Tianjin; Hao in Guangdong Pharmaceutical Industries, ltd, Hao in Guangdong Pharmaceutical Industries, ltd
palmoplantar pustulosis
 
 
ChiCTR2200056779: A real world study for Benvitimod cream in the treatment of lichen simplex chronicus

Not yet recruiting
N/A
50
 
Benvitimod cream
Hainan Meixin Internet hospital; Guang dong Zhonghao Pharmaceutical Co., ltd, Guangdong Zhonghao Pharmaceutical Co., ltd
lichen simplex chronicus
 
 
NCT05326659: Efficacy and Safety of Benvitimod Cream in the Retreatment of Mild to Moderate Psoriasis

Recruiting
N/A
390
RoW
Benvitimod Cream, Placebo
Peking University People's Hospital, Zhonghao Pharmaceutical
Psoriasis
06/23
08/23
Z-VacciRNA / Guanhao Biotech, ZY Therap
No trials found
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Vtama (tapinarof) / Organon
ChiCTR2000032348: A multi-center randomized controlled clinical research in Guangxi to evaluate the efficacy and the safety of topically applied benvitimod cream in patients with plaque psoriasis

Recruiting
4
50
 
1-2W: Halometasone Cream, qd, am; Benvimod Cream, qd, pm; 3-4W: Benvimod Cream, bid, Monday to Friday; Halometasone Cream, bid, Saturday and Sunday; 5-8W: Benvimod Cream, bid. ;1-2W: Halometasone Cream, qd, am; Calcipotriol Ointment, qd, pm; 3-4W: Calcipotriol Ointment, bid, Monday to Friday; Halometasone Cream, bid, Saturday and Sunday; 5-8W: Calcipotriol Ointment, bid.
The Third Affiliated Hospital of Guangxi Medical University; The Third Affiliated Hospital of Guangxi Medical University, Company grants
plaque psoriasis
 
 
ChiCTR2100046872: A study of tapinarof for the treatment of localized scleroderma

Recruiting
4
20
 
Topical benvimod drugs
The Second Xiangya Hospital of Central South University; The Second Xiangya Hospital of Central South University, Self-raised
Localized scleroderma
 
 
NCT05680740: A Study to Investigate Efficacy and Safety of VTAMA (Tapinarof) Cream, 1% in Intertriginous Plaque Psoriasis

Completed
4
34
US
VTAMA® (tapinarof) Cream 1%, DMVT-505
Dermavant Sciences, Inc.
Psoriasis
05/23
05/23
NCT05789576: A Study to Investigate Efficacy and Safety of VTAMA® (Tapinarof) Cream, 1% in Plaque Psoriasis in the Head and Neck Region

Completed
4
31
US
VTAMA (tapinarof) cream, 1%, DMVT-505
Dermavant Sciences, Inc.
Psoriasis
06/23
07/23
ChiCTR2200059396: Efficacy and Safety of Benvitimod Cream in the Retreatment of Mild to Moderate Psoriasis

Not yet recruiting
4
390
 
Benvitimod Cream ;Vertical
Peking University People's Hospital; Guangdong Zhonghao Pharmaceutical Co., Ltd., Guangdong Zhonghao Pharmaceutical Co., Ltd.
Psoriasis
 
 
ChiCTR2100050043: A phase IV clinical trial of Benvitimod to treat mild-to-moderate psoriasis of adults

Not yet recruiting
4
2000
 
external use
Peking University People's Hospital; Level of the institution：, Sponsor
Psoriasis
 
 
NCT06103695: Vtama in Psoriasis Patients Being Treated With Biologics.

Completed
4
30
US
Tapinarof
Psoriasis Treatment Center of Central New Jersey
Psoriasis
10/23
10/23
ChiCTR2000041261: An observational real world study of benvitimod cream in the treatment of psoriasis

Recruiting
4
10000
 
benvitimod cream
Beijing Yuanxin Technology Group Co. LTD; Guangdong Zhonghao Pharmaceutical Co. Ltd., Self-funded
psoriasis
 
 
NCT05064748: Phase IV Clinical Study of Benvitimod Cream in the Treatment of Mild to Moderate Psoriasis in Adults

Recruiting
4
2000
RoW
Benvitimod
Peking University People's Hospital, Zhonghao Pharmaceutical
Psoriasis
03/24
09/24
ChiCTR2100051898: Phase IV Clinical Study of Benvitimod Cream in the Treatment of Mild to Moderate Psoriasis in Adults

Recruiting
4
2000
 
Benvitimod Cream
Peking University People's Hospital; Peking University People's Hospital, Guangdong Zhonghao Pharmaceutical Co., Ltd.
Psoriasis
 
 
ChiCTR2500096856: Real world study of Benvitimod cream in the treatment of chronic simple lichen

Recruiting
4
80
 
NA; NA
Taizhou Central Hospital; Taizhou Central Hospital, Guangdong Zhonghao Pharmaceutical Co., LTD
Chronic simple lichen
 
 
ChiCTR2400085598: A prospective randomized controlled study of Benvermod combined with IL-17 monoclonal antibody in the treatment of refractory lesions of the lower leg in patients with moderate-to-severe plaque psoriasis

Not yet recruiting
4
60
 
Benvitimod cream; Benvitimod Vehicle cream
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine; Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Guangdong Zhonghao Pharmaceutical Co., LTD
Patients with moderate-to-severe plaque psoriasis have intractable lesions of the lower leg
 
 
ChiCTR2500098254: A Multicenter Study on the Impact of Long-Term and Proactive Intermittent Maintenance Treatment with Benvitimod on Psoriasis Recurrence

Not yet recruiting
4
120
 
Apply 1% Benvitimod cream topically to the lesions twice daily (morning and evening) for 12 consecutive weeks; Apply 1% Benvitimod cream twice weekly for 12 weeks; Apply the vehicle cream twice weekly for 12 weeks
Peking University Third Hospital; Peking University Third Hospital, All funding for this research project was provided by Chongqing Zhixiang Jintai Biopharmaceutical Co., Ltd.
Psoriasis
 
 
ChiCTR-TRC-13003259: Multi-centre, randomised, double-blind, placebo- and comparator-controlled trial on topically applied benvitimod cream in patients with psoriasis

Completed
3
720
 
1.0% Benvitimod cream ;Placebo ;Calcipotrione Ointment
People's Hospital of Peking University; Celestial Pharmaceutical (Shenzhen) co., Ltd., Beijing Wenfeng Tianji Pharmaceutical Technology Co., Ltd.
Plaque psoriasis
 
 
NCT05032859: Tapinarof for the Treatment of Atopic Dermatitis in Children and Adults (DMVT-505-3102)

Completed
3
406
Canada, US
tapinarof cream, 1%, vehicle cream
Dermavant Sciences, Inc.
Atopic Dermatitis
02/23
02/23
NCT05014568: Tapinarof for the Treatment of Atopic Dermatitis in Children and Adults

Completed
3
407
Canada, US
tapinarof cream, 1%, Vehicle cream
Dermavant Sciences, Inc.
Atopic Dermatitis
03/23
04/23
NCT05326672: Phase III Clinical Study of Benvitimod Cream in the Treatment of Mild to Moderate Atopic Dermatitis

Recruiting
3
240
RoW
Benvitimod Cream, Placebo
Peking University People's Hospital, Zhonghao Pharmaceutical
Atopic Dermatitis
06/23
12/23
ChiCTR2200059419: Phase III Clinical Study of Benvitimod Cream in the Treatment of Mild to Moderate Atopic Dermatitis

Not yet recruiting
3
240
 
Benvitimod Cream ;Placebo
Peking University People's Hospital; Guangdong Zhonghao Pharmaceutical Co., Ltd., Guangdong Zhonghao Pharmaceutical Co., Ltd.
Atopic Dermatitis
 
 
NCT05142774: Long Term Extension Study of Tapinarof Cream, 1% for Subjects With Atopic Dermatitis

Completed
3
728
Canada, US
Tapinarof cream, 1%
Dermavant Sciences, Inc.
Atopic Dermatitis
02/24
03/24
NCT06742957: Study Comparing Tapinarof Cream 1% to VTAMA ® (Tapinarof Cream 1%) in the Treatment of Plaque Psoriasis

Recruiting
3
560
US
Tapinarof Cream 1%, VTAMA®, Placebo
Teva Pharmaceuticals USA, Teva Pharmaceuticals, Inc.
Plaque Type Psorisis
10/25
11/25
NCT05172726: Tapinarof for the Treatment of Plaque Psoriasis in Pediatric Subjects

Recruiting
3
100
Canada, US
tapinarof cream, 1%
Dermavant Sciences, Inc.
Plaque Psoriasis
09/26
09/26
NCT05981118: Comparison of Post-Inflammatory Pigment Alteration After Psoriasis Treatment (PIPA - Dermavant)

Enrolling by invitation
2/3
40
US
Betamethasone dipropionate 0.05%, Tapinarof
Wake Forest University Health Sciences, Dermavant Sciences, Inc.
ICD10 Code L40.9 for Psoriasis
07/25
12/25
ChiCTR-IIR-17012153: Multi-centre, randomised, double-blind, placebo- and comparator-controlled trial on benvitimod cream in patients with Atopic Dermatitis

Recruiting
2
120
 
0.5% Benvitimod cream ;1.0% Benvitimod cream ;Placebo ;Tacrolimus
Peking University People's Hospital; Beijing Wenfeng Tianji Pharmaceuticals Co., Ltd., Beijing Wenfeng Tianji Pharmaceuticals Co.,Ltd.
Atopic Dermatitis
 
 
NCT06561321: Study to Evaluate the Safety and Efficacy of Tapinarof in Adults With Palmoplantar Keratoderma

Recruiting
2
6
US
Tapinarof
Indiana University, Dermavant Sciences, Inc.
Palmoplantar Keratoderma
02/26
11/26
ChiCTR-TRC-10000995: Pharmacokinetics and Tolerability of Topically Applied Benvitimod Cream in Patients with Psoriasis

Completed
1/2
36
 
0.5% Benvitimod cream ;1.0% Benvitimod cream ;1.5% Benvitimod cream
People's hospital, Peking University; Celestial Pharmaceutical(Shenzhen) co., Ltd., Celestial Pharmaceutical(Shenzhen) co.,Ltd.
Plaque Psoriasis
 
 
ChiCTR-TRC-11001391: Multicentre, randomised, double-blind, placebo controlled trial on topically applied benvitimod cream in patients with psoriasis

Completed
1/2
360
 
0.5% Benvitimod cream ;1.0% Benvitimod cream ;1.0% Benvitimod cream
People's Hospital of Peking University; Celestial Pharmaceutical(Shenzhen) co., Ltd, Celestial Pharmaceutical (Shenzhen) co.,Ltd.
Plaque psoriasis
 
 
ChiCTR1900026921: Study for preliminary efficacy/safety and pharmacokinetics of benvitimod cream in the treatment by systemic exposure of Atopic Dermatitis

Completed
1
6
 
Two times a day for 20 consecutive days
Peking University People's Hospital; Beijing Wenfeng Tianji Pharmaceuticals Co., Ltd., Beijing Wenfeng Tianji Pharmaceuticals Co.,Ltd.
Atopic Dermatitis
 
 
NCT06661213: Tapinarof for Cutaneous Lupus Erythematosus

Not yet recruiting
1
10
US
Tapinarof, VTAMA
Northwestern University
Cutaneous Lupus Erythematosus
03/26
03/26
ChiCTR2100043864: A real world study of Benvimod cream in the treatment of atopic dermatitis and eczema

Completed
N/A
40
 
Benvitimod cream
The First Center Hospital of Tianjin; Hao in Guangdong Pharmaceutical Industries, ltd, Hao in Guangdong Pharmaceutical Industries, ltd
Atopic Dermatitis and Eczema
 
 
ChiCTR2100043862: A real world study for Benvitimod cream in the treatment of Palmoplantar pustulosis

Completed
N/A
48
 
palmar and plantar pustulosis
The First Center Hospital of Tianjin; Hao in Guangdong Pharmaceutical Industries, ltd, Hao in Guangdong Pharmaceutical Industries, ltd
palmoplantar pustulosis
 
 
ChiCTR2200056779: A real world study for Benvitimod cream in the treatment of lichen simplex chronicus

Not yet recruiting
N/A
50
 
Benvitimod cream
Hainan Meixin Internet hospital; Guang dong Zhonghao Pharmaceutical Co., ltd, Guangdong Zhonghao Pharmaceutical Co., ltd
lichen simplex chronicus
 
 
NCT05326659: Efficacy and Safety of Benvitimod Cream in the Retreatment of Mild to Moderate Psoriasis

Recruiting
N/A
390
RoW
Benvitimod Cream, Placebo
Peking University People's Hospital, Zhonghao Pharmaceutical
Psoriasis
06/23
08/23
Z-VacciRNA / Guanhao Biotech, ZY Therap
No trials found

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