Mayne Pharma Trials - LARVOL Sigma

Trial + Data / Events

Status

Region

Interventions

Sponsor

Conditions

Primary compl

Study compl

Sorilux (calcipotriene foam) / Mayne Pharma

NCT04571151: Efficacy and Safety of Sorilux in Maintenance Treatment of Moderate Type Plaque Psoriasis

Not yet recruiting

LEXETTE 0.05% Topical Foam, Halobetasol Propionate Topical Foam, Sorilux 0.005 % Topical Foam, Calcipotriol Foam, Vehicle Foam

Skin Sciences, PLLC

Plaque Psoriasis

11/21

12/21

NCT03370406: Intralesional 5-Fluorouracil (5FU), Topical Calcipotriene Treatment for SCC

Recruiting

5-fluorouracil, Adrucil, Tolak, Efudex, Carac, Fluoroplex, PremierPro Rx Fluorouracil, Fluorouracil Novaplus, 5FU, Calcipotriene, Dovonex, Calcitrene, Sorilux, Calsodore, Kalosar

Melissa Pugliano-Mauro, National Cancer Institute (NCI)

Carcinoma, Squamous Cell

09/26

10/26

Estelle (estetrol/drospirenone) / Mithra, Mayne Pharma, Fuji Pharma, M3 inc

NCT06316180: The Use of Drospirenone/Estetrol in Random Start Rapid Endometrial Preparation

Completed

Europe

drospirenone/estetrol 3mg/14.2mg

University of Palermo, University of Roma La Sapienza

Endometrial Polyp, Endometrial Diseases

08/23

03/24

NCT06324851: The Use of Drospirenone/Estetrol, Nomegestrol Acetate/Estradiol and Ethinylestradiol/Dienogest in Random Start Rapid Endometrial Preparation

Completed

150

Europe

Drospirenone / Estetrol, Nomegestrol Acetate / Estradiol, Ethinylestradiol / Dienogest

University of Palermo, University of Roma La Sapienza

Endometrial Polyp, Endometrial Diseases

08/23

03/24

ERASE, NCT05837624: Estetrol/Drospirenone to Reduce the Average Size of Endometriomas

Recruiting

Canada

Estetrol/Drospirenone

Andrew Zakhari

Ovarian Endometrioma, Endometrioma

11/26

12/26

gusacitinib (ASN002) / Sanofi

NCT06238531: A Clinical Trial to Evaluate Safety of Gusacitinib in Patients With Systemic Lupus Erythematosus (SLE) or Lupus

Withdrawn

Gusacitinib

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Systemic Lupus Erythematosus

01/25

Tolsura (SUBA-itraconazole) / Inhibitor Therap, Mayne Pharma

NCT06732388: Itraconazole in Combination With Ablation for the Prevention of Esophageal Cancer in Patients With High-risk Barrett's Esophagus

Not yet recruiting

Biopsy Procedure, Biopsy, BIOPSY_TYPE, Bx, Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Endoscopic Procedure, Endoscopic Examination, Endoscopy, ES, Itraconazole, Lozanoc, Oriconazole, R 51,211, Sporanox, Placebo Administration, Questionnaire Administration, Radiofrequency Ablation, Ablation, Radiofrequency, Radiofrequency Interstitial Ablation, RFA

National Cancer Institute (NCI)

Barrett Esophagus, Clinical Stage I Esophageal Adenocarcinoma AJCC v8, Clinical Stage IIA Esophageal Adenocarcinoma AJCC v8, Esophageal Adenocarcinoma

01/28

HITMAN, NCT03513211: Phase I/II Study of Hydroxychloroquine With Itraconazole With Biochemically Recurrent Prostate Cancer

Completed

1/2

RoW

SUBA-itraconazole, Hydroxychloroquine

St Vincent's Hospital, Sydney

Prostate Cancer

08/23

10/23

KOMET-001, NCT04067336 / 2019-001545-41: First in Human Study of Ziftomenib in Relapsed or Refractory Acute Myeloid Leukemia

Recruiting

1/2

263

Europe, Canada, US

Ziftomenib, KO-539, Midazolam, Seizalam, Hypnovel, Dormicum, Itraconazole, Sporanox, Onmel, Tolsura

Kura Oncology, Inc., Kura Oncology, Inc.

Advanced Malignant Neoplasm, Acute Myeloid Leukemia, Mixed Lineage Leukemia, Mixed Lineage Acute Leukemia, Acute Leukemia of Ambiguous Lineage, Mixed Phenotype Acute Leukemia, Acute Lymphoblastic Leukemia

10/28

TICTOC, NCT05156892: Tamoxifen and SUBA-Itraconzole Combination Testing in Ovarian Cancer

Active, not recruiting

RoW

SUBA-itraconazole, Tamoxifen

Anthony Joshua, FRACP, Royal Prince Alfred Hospital, Sydney, Australia, Concord Hospital, Prince of Wales Hospital, Sydney, St Vincent's Hospital, Sydney

Ovarian Cancer

01/26

01/27

Tolsura, NCT04652050: Evaluation of When Used as Prophylaxis After Lung Transplantation

Withdrawn

N/A

Tolsura

Hong Nguyen

Lung Transplant Infection

04/23

Trial + Data / Events

Status

Region

Interventions

Sponsor

Conditions

Primary compl

Study compl

Sorilux (calcipotriene foam) / Mayne Pharma

NCT04571151: Efficacy and Safety of Sorilux in Maintenance Treatment of Moderate Type Plaque Psoriasis

Not yet recruiting

LEXETTE 0.05% Topical Foam, Halobetasol Propionate Topical Foam, Sorilux 0.005 % Topical Foam, Calcipotriol Foam, Vehicle Foam

Skin Sciences, PLLC

Plaque Psoriasis

11/21

12/21

NCT03370406: Intralesional 5-Fluorouracil (5FU), Topical Calcipotriene Treatment for SCC

Recruiting

5-fluorouracil, Adrucil, Tolak, Efudex, Carac, Fluoroplex, PremierPro Rx Fluorouracil, Fluorouracil Novaplus, 5FU, Calcipotriene, Dovonex, Calcitrene, Sorilux, Calsodore, Kalosar

Melissa Pugliano-Mauro, National Cancer Institute (NCI)

Carcinoma, Squamous Cell

09/26

10/26

Estelle (estetrol/drospirenone) / Mithra, Mayne Pharma, Fuji Pharma, M3 inc

NCT06316180: The Use of Drospirenone/Estetrol in Random Start Rapid Endometrial Preparation

Completed

Europe

drospirenone/estetrol 3mg/14.2mg

University of Palermo, University of Roma La Sapienza

Endometrial Polyp, Endometrial Diseases

08/23

03/24

NCT06324851: The Use of Drospirenone/Estetrol, Nomegestrol Acetate/Estradiol and Ethinylestradiol/Dienogest in Random Start Rapid Endometrial Preparation

Completed

150

Europe

Drospirenone / Estetrol, Nomegestrol Acetate / Estradiol, Ethinylestradiol / Dienogest

University of Palermo, University of Roma La Sapienza

Endometrial Polyp, Endometrial Diseases

08/23

03/24

ERASE, NCT05837624: Estetrol/Drospirenone to Reduce the Average Size of Endometriomas

Recruiting

Canada

Estetrol/Drospirenone

Andrew Zakhari

Ovarian Endometrioma, Endometrioma

11/26

12/26

gusacitinib (ASN002) / Sanofi

NCT06238531: A Clinical Trial to Evaluate Safety of Gusacitinib in Patients With Systemic Lupus Erythematosus (SLE) or Lupus

Withdrawn

Gusacitinib

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Systemic Lupus Erythematosus

01/25

Tolsura (SUBA-itraconazole) / Inhibitor Therap, Mayne Pharma

NCT06732388: Itraconazole in Combination With Ablation for the Prevention of Esophageal Cancer in Patients With High-risk Barrett's Esophagus

Not yet recruiting

National Cancer Institute (NCI)

Barrett Esophagus, Clinical Stage I Esophageal Adenocarcinoma AJCC v8, Clinical Stage IIA Esophageal Adenocarcinoma AJCC v8, Esophageal Adenocarcinoma

01/28

HITMAN, NCT03513211: Phase I/II Study of Hydroxychloroquine With Itraconazole With Biochemically Recurrent Prostate Cancer

Completed

1/2

RoW

SUBA-itraconazole, Hydroxychloroquine

St Vincent's Hospital, Sydney

Prostate Cancer

08/23

10/23

KOMET-001, NCT04067336 / 2019-001545-41: First in Human Study of Ziftomenib in Relapsed or Refractory Acute Myeloid Leukemia

Recruiting

1/2

263

Europe, Canada, US

Ziftomenib, KO-539, Midazolam, Seizalam, Hypnovel, Dormicum, Itraconazole, Sporanox, Onmel, Tolsura

Kura Oncology, Inc., Kura Oncology, Inc.

Advanced Malignant Neoplasm, Acute Myeloid Leukemia, Mixed Lineage Leukemia, Mixed Lineage Acute Leukemia, Acute Leukemia of Ambiguous Lineage, Mixed Phenotype Acute Leukemia, Acute Lymphoblastic Leukemia

10/28

TICTOC, NCT05156892: Tamoxifen and SUBA-Itraconzole Combination Testing in Ovarian Cancer

Active, not recruiting

RoW

SUBA-itraconazole, Tamoxifen

Anthony Joshua, FRACP, Royal Prince Alfred Hospital, Sydney, Australia, Concord Hospital, Prince of Wales Hospital, Sydney, St Vincent's Hospital, Sydney

Ovarian Cancer

01/26

01/27

Tolsura, NCT04652050: Evaluation of When Used as Prophylaxis After Lung Transplantation

Withdrawn

N/A

Tolsura

Hong Nguyen

Lung Transplant Infection

04/23



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