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Trial + Data / Events	Status	Ph	N	Region	Interventions	Sponsor	Conditions	Primary compl	Study compl
ersodetug (RZ358) / Rezolute
sunRIZE, NCT06208215: RZ358 Treatment for Congenital Hyperinsulinism	Recruiting	3	56	Europe, Canada, US, RoW	RZ358 (5 mg/kg) + SOC (Standard-of-Care) or Placebo + SOC, RZ358 (10 mg/kg) or Placebo + SOC, RZ358 (5-10 mg/kg) + SOC	Rezolute	Congenital Hyperinsulinism	04/25	09/26
NCT06881992: A Phase 3 Study of Ersodetug in Patients With Tumor-Associated Hyperinsulinism	Recruiting	3	48	US	Ersodetug, Placebo	Rezolute	Tumor- Associated Hyperinsulinism	09/27	09/27
RZ402 / Rezolute
NCT05712720: Study to Evaluate the Efficacy and Safety of RZ402 in Diabetic Macular Edema (DME)	Active, not recruiting	2	100	US	Experimental: Group 1 - 50mg RZ402, Experimental: Group 2 - 200mg RZ402, Experimental: Group 3 - 400mg RZ402, Placebo: Group 4 - Placebo	Rezolute	Diabetic Macular Edema	05/24	05/25

Trial + Data / Events	Status	Ph	N	Region	Interventions	Sponsor	Conditions	Primary compl	Study compl
ersodetug (RZ358) / Rezolute
sunRIZE, NCT06208215: RZ358 Treatment for Congenital Hyperinsulinism	Recruiting	3	56	Europe, Canada, US, RoW	RZ358 (5 mg/kg) + SOC (Standard-of-Care) or Placebo + SOC, RZ358 (10 mg/kg) or Placebo + SOC, RZ358 (5-10 mg/kg) + SOC	Rezolute	Congenital Hyperinsulinism	04/25	09/26
NCT06881992: A Phase 3 Study of Ersodetug in Patients With Tumor-Associated Hyperinsulinism	Recruiting	3	48	US	Ersodetug, Placebo	Rezolute	Tumor- Associated Hyperinsulinism	09/27	09/27
RZ402 / Rezolute
NCT05712720: Study to Evaluate the Efficacy and Safety of RZ402 in Diabetic Macular Edema (DME)	Active, not recruiting	2	100	US	Experimental: Group 1 - 50mg RZ402, Experimental: Group 2 - 200mg RZ402, Experimental: Group 3 - 400mg RZ402, Placebo: Group 4 - Placebo	Rezolute	Diabetic Macular Edema	05/24	05/25