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42 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Dextenza (dexamethasone ophthalmic insert) / Ocular Therap
NCT04396990: The RESTORE Study, A Randomized, Controlled, Masked (Reading Center) Prospective Study

Completed
4
20
US
Dextenza 0.4Mg Ophthalmic Insert, Topical Prednisolone
Vance Thompson Vision, Ocular Therapeutix, Inc.
Refractive Surgery
09/20
09/20
NCT04530864: Pre-Surgical Ocular Surface Treatment With Intracanalicular Dexamethasone Insert And Effect On Intraocular Lens Measurement Accuracy

Not yet recruiting
4
35
NA
Dextenza 0.4Mg Ophthalmic Insert
Prism Vision Group, Ocular Therapeutix, Inc.
Dry Eye Disease, Cataract Surgery, Ocular Surface Disease
01/21
07/21
NCT04592081: Dextenza Within Upper Lid Canaliculus Compared With Lower Lid Canaliculus Following Bilateral Cataract Extraction Surgery With PCIOL.

Recruiting
4
20
US
Dextenza 0.4Mg Ophthalmic Insert
Kerry Assil, MD
Post-Surgical Ocular Pain, Post-Surgical Ocular Inflammation
02/21
03/21
INDEX, NCT04529512: INtravitreal and Aqueous Dexamethasone Levels After DEXtenza

Not yet recruiting
4
40
US
DEXTENZA®, dexamethasone ophthalmic insert 0.4mg
Nathan Steinle, Ocular Therapeutix, Inc.
Ocular Disease Requiring Surgery
03/21
03/21
ENHANCE, NCT04863742: Evaluation Of Vision Recovery And Comfort Index In Patients With Borderline/Mild Dry Eyes Undergoing FLACS With Premium IOL

Recruiting
4
30
US
Dextenza 0.4Mg Ophthalmic Insert, Prednisolone Acetate
Sight Medical Doctors PLLC, Ocular Therapeutix, Inc.
Dry Eye Syndromes
07/21
09/21
NCT04549935: The PRIME Study: A Randomized, Controlled, Prospective Study

Recruiting
4
20
US
Dextenza, Topical Prednisolone
Vance Thompson Vision - MT
Patient Preference, Patient Outcomes, Post-Operative Inflammation, Grade of Post-Operative Cystoid Macular Edema, Rate of Post-Operative Cystoid Macular Edema
08/21
08/21
NCT05100186: The SITE Study - Dexamethasone Ophthalmic Insert In OR on Day of Surgery Versus In-office Post-Op Day 1

Not yet recruiting
4
50
NA
Dexamethasone 0.4 MG [Dextenza]
Joseph Kavanagh, MD
Cataract
12/21
02/22
NCT04977427: Dextenza vs Prednisolone Acetate After Cataract Surgery for Patients With Diabetes

Not yet recruiting
4
200
NA
Dextenza 0.4Mg Ophthalmic Insert, Prednisolone Acetate 1% Oph Susp
Baylor Research Institute
Cataract Diabetic, Macula Edema
01/22
03/22
NCT04362241: DEXTENZA VS. PREDNISOLONE ACETATE 1% Macular Edema With Diabetic Retinopathy After Cataract Surgery

Recruiting
4
30
US
Prednisolone Acetate 1% Ophthalmic Suspension [PRED FORTE], Prednisolone Acetate 1%
Ophthalmic Consultants of the Capital Region
Retinopathy, Diabetic
02/22
03/22
NCT04462523: DEXTENZA for the Treatment of Postoperative Pain and Inflammation Following Vitreo-retinal Surgery

Completed
4
40
US
Dextenza 0.4Mg Ophthalmic Insert, Topical Prednisolone
Patrick R. Oellers, MD, Ocular Therapeutix, Inc.
Vitreo-Retinal Surgery
03/22
03/22
PERSIST, NCT04351737: Dextenza for Post-operative Treatment of Pterygium

Completed
4
20
US
Intracanalicular Dexamethasone, (0.4 mg) Insert, Dextenza, Prednisolone Acetate
Brandon Eye Associates, PA
Pterygium of Both Eyes
07/22
05/23
NCT05023304: In Clinic Optometrist Insertion of Dextenza Prior to Cataract Surgery

Not yet recruiting
4
30
NA
Dextenza 0.4Mg Ophthalmic Insert, Topical Prednisolone
Mitchel Ibach, Ocular Therapeutix, Inc.
Cataract
07/22
10/22
NCT04168112: Intracanalicular Dexamethasone Insert for Post-Corneal Cross-Linking Inflammation and Pain- The LINK Study

Completed
4
20
US
Dextenza, Intracanalicular dexamethasone insert, Prednisolone Acetate
Sight Medical Doctors PLLC, Ocular Therapeutix, Inc.
Keratoconus, Unstable, Collagen Crosslinking, Postoperative Pain
10/22
04/23
NCT04839549: Efficacy and Safety of Dextenza Compared to Topical Fluorometholone in Patients With Ocular Rosacea

Withdrawn
4
50
NA
Dextenza 0.4Mg Ophthalmic Insert, Fluoromethalone .01%
Eye Associates of Central Texas
Ocular Rosacea
11/22
11/22
NCT04479748: DEXTENZA Compared to Topical Steroid Therapy Prior to Cataract Surgery in Patients Who Receive Premium Intraocular Lenses

Completed
4
13
US
Dexamethasone, Prednisolone Acetate 1% Oph Susp
Prism Vision Group
Cataract
12/22
12/22
NCT04521140: Assessing eFficacy and Safety of DEXTENZA 0.4 mg inseRt, Following Corneal Transplant Surgery

Completed
4
36
US
Dextenza 0.4Mg Ophthalmic Insert, Dexamethasone Ophthalmic Insert, Prednisolone Acetate 1% Oph Susp, Omnipred, Pred Forte
Nicole Fram M.D.
Corneal Edema, Corneal Defect, Corneal Transplant, Penetrating KeratoPlasty, Anterior Chamber Inflammation, Ocular Pain, Intraocular Pressure
01/23
01/23
FINNEN, NCT04464629: Assessing the Efficacy and Safety of DEXTENZA in Pseudo Phakic Patients Undergoing Gas Bubble Repair and Laser Following Retinal Detachment

Terminated
4
7
US
Dextenza, Prednisolone Acetate
Midwest Eye Institute, Ocular Therapeutix, Inc.
Retinal Detachment
01/23
01/23
NCT05143281: The SITE Study - Dexamethasone Ophthalmic Insert In OR on Day of Surgery Versus In-office Post-Op Day 1

Completed
4
23
US
Dexamethasone 0.4 MG [Dextenza], Dextenza
Grene Vision Group, Ocular Therapeutix, Inc.
Cataract
02/23
02/23
DETeR, NCT04563299: Effect on Pain and Inflammation With DEXTENZA Treatment in Patients Undergoing Intravitreal Anti-VEGF Injections

Terminated
4
10
US
Dextenza 0.4Mg Ophthalmic Insert, Prednisolone Acetate
Retina Vitreous Associates of Florida, Ocular Therapeutix, Inc.
Neovascular Age-related Macular Degeneration, Diabetic Macular Edema, Retinal Vein Occlusion
02/23
02/23
NCT04498468: Safety and Efficacy of Dexamethasone Ophthalmic Insert (Dextenza®) in the Management of Clinically Significant Dry Eye

Terminated
4
77
US
Sustained Release Dexamethasone, 0.4 mg, Dextenza, E-Caprolactone-L-Lactide copolymer (PCL) punctal plug, EXTENDED WEAR SYNTHETIC ABSORBABLE PUNCTAL PLUG
Johns Hopkins University
Dry Eye
03/23
03/23
SUSTAIN, NCT04200651: Prospective Study on DEXTENZA® Safety And Efficacy Following Concomitant MIGS and Cataract Surgery

Terminated
4
25
US
Dexamethasone Ophthalmic Insert, DEXTENZA®, Prednisolone Acetate 1% Oph Susp, PRED FORTE®, OMNIPRED®
The New York Eye Surgery Center, Ocular Therapeutix, Inc.
Glaucoma, Cataract
07/23
07/23
NCT05665270: A Study for Post op Inflammation After Cataract Surgery

Enrolling by invitation
4
40
US
Dextenza 0.4Mg Ophthalmic Insert, Prednisolone Acetate 1%
Wyse Eyecare
Cataract
10/23
12/23
DEXTenSiVe, NCT05116345: DEXTENZA for the Treatment of Pain and Inflammation Following Surgical Trabeculectomy and Ahmed Valve Procedures

Not yet recruiting
4
30
US
DEXTENZA, Dexamethasone (0.4mg) Insert, Topical Dexamethasone
Brian Jerkins, MD, Ocular Therapeutix, Inc.
Glaucoma Following Surgery
11/23
11/23
NCT04371445: Dextenza in the Post-op Management of Vitreoretinal Surgeries

Recruiting
4
30
US
Dexamethasone Ophthalmic Insert, DEXTENZA®, Prednisolone Acetate 1% Oph Susp, PRED FORTE®, OMNIPRED®
The Cleveland Clinic, Ocular Therapeutix, Inc.
Vitreoretinal Surgery, Ocular Inflammation, Post-operative Pain, Post-Operative Inflammation
12/25
12/25
DEcIDED, NCT04527887: Intracanalicular Dexamethasone Insert for the Treatment of Inflammation and Discomfort in Dry Eye Disease

Terminated
4
54
US
Dextenza (IDI) (Sustained Release Dexamethasone), (0.4 mg), ProLong™ collagen plugs
Tufts Medical Center, Ocular Therapeutix, Inc.
Dry Eye
11/23
12/24
NCT05626478: Assessing eFficacy and Safety of DEXTENZA 0.4 mg inseRt, Following Cataract Surgery

Active, not recruiting
4
50
US
Dextenza 0.4Mg Ophthalmic Insert, Dexamethasone 0.4mg, Prednisolone Acetate 1% Oph Susp, Prolensa 0.07% Ophthalmic Solution
Nicole Fram M.D.
Corneal Edema, Corneal Defect, Anterior Chamber Inflammation, Ocular Pain, Corneal Staining, Visual Outcome, CME - Cystoid Macular Edema
04/25
04/25
NCT05587231: Comparison of the Postoperative Use of Dextenza vs a Standard Regimen After PRK

Not yet recruiting
4
60
NA
Dextenza 0.4Mg Ophthalmic Insert, Topical Fluorometholone
Navy Medical Center San Diego
Steroid Ophthalmic Insert
10/24
10/24
NCT04501367: Assessing the Efficacy and Safety fo DEXTENZA, Sustained Release Dexamethasone 0.4 mg Insert(s) for the Treatment of Pain, Inflammation, and Cystoid Macular Edema Following 27 Gauge Vitrectomy With Internal Limiting Membrane Peel for the Treatment of Retinal Edema Associated With Macular Pucker.

Recruiting
4
60
US
Dexamethasone Intracanalicular Insert, 0.4 mg, Prednisone acetate 1%
Kovach Eye Institute
Vitrectomy, Macular Pucker, Retinal Edema
12/24
12/24
NCT04539548: A Study Assessing the Safety and Efficacy of Dextenza® for the Treatment of Ocular Pain and Inflammation Following Surgery for Pediatric Cataract

Completed
3
65
US
Dextenza Ophthalmic Insert, DEXTENZA, Prednisolone acetate ophthalmic suspension USP 1%
Ocular Therapeutix, Inc.
Cataract
12/23
12/23
NCT04661137: A Study of Selinexor, in Combination With Carfilzomib, Daratumumab or Pomalidomide in Patients With Multiple Myeloma

Suspended
2
96
US
Selinexor 60 MG, KPT-330, Selinexor 80 MG, Selinexor 100 MG, Carfilzomib, Kyprolis, Pomalidomide, Pomalyst, Daratumumab, Darzalex, Dexamethasone, Dextenza, Ozurdex, Neofordex, others
Hackensack Meridian Health, Karyopharm Therapeutics Inc
Multiple Myeloma
01/26
01/26
NCT06235567: Dextenza Versus Topical Steroid Eye Drops for Postoperative Management Following Corneal Crosslinking

Enrolling by invitation
1/2
20
US
Dextenza 0.4Mg Ophthalmic Insert, topical prednisolone acetate 1% (PredForte) eye drops
Maanasa Indaram, MD
Keratoconus
12/25
06/26
NCT05620901: DEXTENZA in Pediatric Patients Following Retinal Surgery or Laser Treatment Under Anesthesia

Recruiting
1
30
US
Dextenza 0.4Mg Ophthalmic Insert, Pred Forte
Lejla Vajzovic, MD, FASRS
Vitreoretinopathy, Coats' Disease, Exudative Retinopathy, Lattice Degeneration, Retinal Hole, Sickler's Syndrome, Retinal Detachment Rhegmatogenous, Retinal Detachment Exudative, Retinal Detachment Traction
04/25
04/25
ChiCTR2400079737: A Real-world Study of DEXTENZA® for the Treatment of Ocular Inflammation and Pain after Cataract Surgery

Completed
N/A
120
 
Dexamethasone Ophthalmic Insert
Boao Super Hospital; Shanghai AffaMed Therapeutics Co., Ltd., self-funding
Ocular inflammation and pain following ophthalmic surgery
 
 
Paxtrava (travoprost intracameral implant) / Ocular Therap
NCT05335122: A Study to Evaluate the Efficacy and Safety of OTX-TIC (Travoprost) Intracameral Implant for Patients With Open-angle Glaucoma (OAG) or Ocular Hypertension (OHT)

Completed
2
83
US
OTX-TIC low dose Travoprost Intracameral Implant, OTX-TIC high dose Travoprost Intracameral Implant, Durysta, Bimatoprost Intracameral Implant 10 µg
Ocular Therapeutix, Inc.
Open Angle Glaucoma, Ocular Hypertension
01/24
01/25
NCT04360174: CLN-0045: Safety, and Efficacy of OTX-TIC in Participants With Open Angle Glaucoma or Ocular Hypertension

Completed
1
19
US
OTX-TIC
Ocular Therapeutix, Inc.
Ocular Hypertension, Open Angle Glaucoma
05/21
05/21
The XU Study, NCT05835141: Rates and Risk Factors of Contact Between the OTX-TIC Intracameral Ocular Implant and Corneal Endothelium

Recruiting
N/A
100
US
OCT Imaging
University of Southern California
Corneal Endothelium
01/24
05/24
Axpaxli (intravitreal axitinib implant) / Ocular Therap
OTX-TKI-2023-AMD-301, NCT06223958: Study to Evaluate the Efficacy and Safety of Intravitreal OTX-TKI (Ocular Therapeutix) (Axitinib Implant) in Subjects With Neovascular Age-Related Macular Degeneration

Active, not recruiting
3
344
US, RoW
OTX-TKI (axitinib implant), Aflibercept
Ocular Therapeutix, Inc., Fortrea, Duke University
Neovascular Age-Related Macular Degeneration
04/26
09/27
OTX-TKI-2023-AMD-303, NCT06495918: Study to Evaluate the Efficacy and Safety of Intravitreal OTX-TKI (Axitinib Implant) in Subjects With Neovascular Age- Related Macular Degeneration

Active, not recruiting
3
825
US, RoW
OTX-TKI, Aflibercept
Ocular Therapeutix, Inc., Fortrea, Duke University
Neovascular Age-related Macular Degeneration
01/27
01/27
NCT03630315: CLN-0046: Treatment of AMD Subjects With OTX-TKI

Completed
1
29
RoW
OTX-TKI, Anti-VEGF, aflibercept, bevacizumab, ranibizumab
Ocular Therapeutix, Inc.
Neovascular Age-related Macular Degeneration
01/24
01/24
NCT04989699: Study Evaluating the Treatment of OTX-TKI for Subjects With Neovascular Age-related Macular Degeneration

Completed
1
21
US
OTX-TKI/Sham, Aflibercept/Sham, Eylea
Ocular Therapeutix, Inc.
Neovascular Age-Related Macular Degeneration
02/23
12/23
OTX-TKI-2022-101, NCT05695417: Study to Evaluate the Safety, Tolerability, and Efficacy of OTX-TKI in Subjects With Moderately Severe to Severe Non-proliferative Diabetic Retinopathy

Active, not recruiting
1
21
US
OTX-TKI, Sham
Ocular Therapeutix, Inc.
Non-proliferative Diabetic Retinopathy
01/24
12/24
dexamethasone intracanalicular insert (OTX-DED) / Ocular Therap
NCT05814757: OTX-DED for the Short-term Treatment of the Symptoms of Dry Eye Disease (DED)

Completed
2
100
US
OTX-DED, Controlled Insertion, Collagen Punctal Plug
Ocular Therapeutix, Inc.
Dry Eye Syndromes, Eye Diseases
05/24
05/24
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Dextenza (dexamethasone ophthalmic insert) / Ocular Therap
NCT04396990: The RESTORE Study, A Randomized, Controlled, Masked (Reading Center) Prospective Study

Completed
4
20
US
Dextenza 0.4Mg Ophthalmic Insert, Topical Prednisolone
Vance Thompson Vision, Ocular Therapeutix, Inc.
Refractive Surgery
09/20
09/20
NCT04530864: Pre-Surgical Ocular Surface Treatment With Intracanalicular Dexamethasone Insert And Effect On Intraocular Lens Measurement Accuracy

Not yet recruiting
4
35
NA
Dextenza 0.4Mg Ophthalmic Insert
Prism Vision Group, Ocular Therapeutix, Inc.
Dry Eye Disease, Cataract Surgery, Ocular Surface Disease
01/21
07/21
NCT04592081: Dextenza Within Upper Lid Canaliculus Compared With Lower Lid Canaliculus Following Bilateral Cataract Extraction Surgery With PCIOL.

Recruiting
4
20
US
Dextenza 0.4Mg Ophthalmic Insert
Kerry Assil, MD
Post-Surgical Ocular Pain, Post-Surgical Ocular Inflammation
02/21
03/21
INDEX, NCT04529512: INtravitreal and Aqueous Dexamethasone Levels After DEXtenza

Not yet recruiting
4
40
US
DEXTENZA®, dexamethasone ophthalmic insert 0.4mg
Nathan Steinle, Ocular Therapeutix, Inc.
Ocular Disease Requiring Surgery
03/21
03/21
ENHANCE, NCT04863742: Evaluation Of Vision Recovery And Comfort Index In Patients With Borderline/Mild Dry Eyes Undergoing FLACS With Premium IOL

Recruiting
4
30
US
Dextenza 0.4Mg Ophthalmic Insert, Prednisolone Acetate
Sight Medical Doctors PLLC, Ocular Therapeutix, Inc.
Dry Eye Syndromes
07/21
09/21
NCT04549935: The PRIME Study: A Randomized, Controlled, Prospective Study

Recruiting
4
20
US
Dextenza, Topical Prednisolone
Vance Thompson Vision - MT
Patient Preference, Patient Outcomes, Post-Operative Inflammation, Grade of Post-Operative Cystoid Macular Edema, Rate of Post-Operative Cystoid Macular Edema
08/21
08/21
NCT05100186: The SITE Study - Dexamethasone Ophthalmic Insert In OR on Day of Surgery Versus In-office Post-Op Day 1

Not yet recruiting
4
50
NA
Dexamethasone 0.4 MG [Dextenza]
Joseph Kavanagh, MD
Cataract
12/21
02/22
NCT04977427: Dextenza vs Prednisolone Acetate After Cataract Surgery for Patients With Diabetes

Not yet recruiting
4
200
NA
Dextenza 0.4Mg Ophthalmic Insert, Prednisolone Acetate 1% Oph Susp
Baylor Research Institute
Cataract Diabetic, Macula Edema
01/22
03/22
NCT04362241: DEXTENZA VS. PREDNISOLONE ACETATE 1% Macular Edema With Diabetic Retinopathy After Cataract Surgery

Recruiting
4
30
US
Prednisolone Acetate 1% Ophthalmic Suspension [PRED FORTE], Prednisolone Acetate 1%
Ophthalmic Consultants of the Capital Region
Retinopathy, Diabetic
02/22
03/22
NCT04462523: DEXTENZA for the Treatment of Postoperative Pain and Inflammation Following Vitreo-retinal Surgery

Completed
4
40
US
Dextenza 0.4Mg Ophthalmic Insert, Topical Prednisolone
Patrick R. Oellers, MD, Ocular Therapeutix, Inc.
Vitreo-Retinal Surgery
03/22
03/22
PERSIST, NCT04351737: Dextenza for Post-operative Treatment of Pterygium

Completed
4
20
US
Intracanalicular Dexamethasone, (0.4 mg) Insert, Dextenza, Prednisolone Acetate
Brandon Eye Associates, PA
Pterygium of Both Eyes
07/22
05/23
NCT05023304: In Clinic Optometrist Insertion of Dextenza Prior to Cataract Surgery

Not yet recruiting
4
30
NA
Dextenza 0.4Mg Ophthalmic Insert, Topical Prednisolone
Mitchel Ibach, Ocular Therapeutix, Inc.
Cataract
07/22
10/22
NCT04168112: Intracanalicular Dexamethasone Insert for Post-Corneal Cross-Linking Inflammation and Pain- The LINK Study

Completed
4
20
US
Dextenza, Intracanalicular dexamethasone insert, Prednisolone Acetate
Sight Medical Doctors PLLC, Ocular Therapeutix, Inc.
Keratoconus, Unstable, Collagen Crosslinking, Postoperative Pain
10/22
04/23
NCT04839549: Efficacy and Safety of Dextenza Compared to Topical Fluorometholone in Patients With Ocular Rosacea

Withdrawn
4
50
NA
Dextenza 0.4Mg Ophthalmic Insert, Fluoromethalone .01%
Eye Associates of Central Texas
Ocular Rosacea
11/22
11/22
NCT04479748: DEXTENZA Compared to Topical Steroid Therapy Prior to Cataract Surgery in Patients Who Receive Premium Intraocular Lenses

Completed
4
13
US
Dexamethasone, Prednisolone Acetate 1% Oph Susp
Prism Vision Group
Cataract
12/22
12/22
NCT04521140: Assessing eFficacy and Safety of DEXTENZA 0.4 mg inseRt, Following Corneal Transplant Surgery

Completed
4
36
US
Dextenza 0.4Mg Ophthalmic Insert, Dexamethasone Ophthalmic Insert, Prednisolone Acetate 1% Oph Susp, Omnipred, Pred Forte
Nicole Fram M.D.
Corneal Edema, Corneal Defect, Corneal Transplant, Penetrating KeratoPlasty, Anterior Chamber Inflammation, Ocular Pain, Intraocular Pressure
01/23
01/23
FINNEN, NCT04464629: Assessing the Efficacy and Safety of DEXTENZA in Pseudo Phakic Patients Undergoing Gas Bubble Repair and Laser Following Retinal Detachment

Terminated
4
7
US
Dextenza, Prednisolone Acetate
Midwest Eye Institute, Ocular Therapeutix, Inc.
Retinal Detachment
01/23
01/23
NCT05143281: The SITE Study - Dexamethasone Ophthalmic Insert In OR on Day of Surgery Versus In-office Post-Op Day 1

Completed
4
23
US
Dexamethasone 0.4 MG [Dextenza], Dextenza
Grene Vision Group, Ocular Therapeutix, Inc.
Cataract
02/23
02/23
DETeR, NCT04563299: Effect on Pain and Inflammation With DEXTENZA Treatment in Patients Undergoing Intravitreal Anti-VEGF Injections

Terminated
4
10
US
Dextenza 0.4Mg Ophthalmic Insert, Prednisolone Acetate
Retina Vitreous Associates of Florida, Ocular Therapeutix, Inc.
Neovascular Age-related Macular Degeneration, Diabetic Macular Edema, Retinal Vein Occlusion
02/23
02/23
NCT04498468: Safety and Efficacy of Dexamethasone Ophthalmic Insert (Dextenza®) in the Management of Clinically Significant Dry Eye

Terminated
4
77
US
Sustained Release Dexamethasone, 0.4 mg, Dextenza, E-Caprolactone-L-Lactide copolymer (PCL) punctal plug, EXTENDED WEAR SYNTHETIC ABSORBABLE PUNCTAL PLUG
Johns Hopkins University
Dry Eye
03/23
03/23
SUSTAIN, NCT04200651: Prospective Study on DEXTENZA® Safety And Efficacy Following Concomitant MIGS and Cataract Surgery

Terminated
4
25
US
Dexamethasone Ophthalmic Insert, DEXTENZA®, Prednisolone Acetate 1% Oph Susp, PRED FORTE®, OMNIPRED®
The New York Eye Surgery Center, Ocular Therapeutix, Inc.
Glaucoma, Cataract
07/23
07/23
NCT05665270: A Study for Post op Inflammation After Cataract Surgery

Enrolling by invitation
4
40
US
Dextenza 0.4Mg Ophthalmic Insert, Prednisolone Acetate 1%
Wyse Eyecare
Cataract
10/23
12/23
DEXTenSiVe, NCT05116345: DEXTENZA for the Treatment of Pain and Inflammation Following Surgical Trabeculectomy and Ahmed Valve Procedures

Not yet recruiting
4
30
US
DEXTENZA, Dexamethasone (0.4mg) Insert, Topical Dexamethasone
Brian Jerkins, MD, Ocular Therapeutix, Inc.
Glaucoma Following Surgery
11/23
11/23
NCT04371445: Dextenza in the Post-op Management of Vitreoretinal Surgeries

Recruiting
4
30
US
Dexamethasone Ophthalmic Insert, DEXTENZA®, Prednisolone Acetate 1% Oph Susp, PRED FORTE®, OMNIPRED®
The Cleveland Clinic, Ocular Therapeutix, Inc.
Vitreoretinal Surgery, Ocular Inflammation, Post-operative Pain, Post-Operative Inflammation
12/25
12/25
DEcIDED, NCT04527887: Intracanalicular Dexamethasone Insert for the Treatment of Inflammation and Discomfort in Dry Eye Disease

Terminated
4
54
US
Dextenza (IDI) (Sustained Release Dexamethasone), (0.4 mg), ProLong™ collagen plugs
Tufts Medical Center, Ocular Therapeutix, Inc.
Dry Eye
11/23
12/24
NCT05626478: Assessing eFficacy and Safety of DEXTENZA 0.4 mg inseRt, Following Cataract Surgery

Active, not recruiting
4
50
US
Dextenza 0.4Mg Ophthalmic Insert, Dexamethasone 0.4mg, Prednisolone Acetate 1% Oph Susp, Prolensa 0.07% Ophthalmic Solution
Nicole Fram M.D.
Corneal Edema, Corneal Defect, Anterior Chamber Inflammation, Ocular Pain, Corneal Staining, Visual Outcome, CME - Cystoid Macular Edema
04/25
04/25
NCT05587231: Comparison of the Postoperative Use of Dextenza vs a Standard Regimen After PRK

Not yet recruiting
4
60
NA
Dextenza 0.4Mg Ophthalmic Insert, Topical Fluorometholone
Navy Medical Center San Diego
Steroid Ophthalmic Insert
10/24
10/24
NCT04501367: Assessing the Efficacy and Safety fo DEXTENZA, Sustained Release Dexamethasone 0.4 mg Insert(s) for the Treatment of Pain, Inflammation, and Cystoid Macular Edema Following 27 Gauge Vitrectomy With Internal Limiting Membrane Peel for the Treatment of Retinal Edema Associated With Macular Pucker.

Recruiting
4
60
US
Dexamethasone Intracanalicular Insert, 0.4 mg, Prednisone acetate 1%
Kovach Eye Institute
Vitrectomy, Macular Pucker, Retinal Edema
12/24
12/24
NCT04539548: A Study Assessing the Safety and Efficacy of Dextenza® for the Treatment of Ocular Pain and Inflammation Following Surgery for Pediatric Cataract

Completed
3
65
US
Dextenza Ophthalmic Insert, DEXTENZA, Prednisolone acetate ophthalmic suspension USP 1%
Ocular Therapeutix, Inc.
Cataract
12/23
12/23
NCT04661137: A Study of Selinexor, in Combination With Carfilzomib, Daratumumab or Pomalidomide in Patients With Multiple Myeloma

Suspended
2
96
US
Selinexor 60 MG, KPT-330, Selinexor 80 MG, Selinexor 100 MG, Carfilzomib, Kyprolis, Pomalidomide, Pomalyst, Daratumumab, Darzalex, Dexamethasone, Dextenza, Ozurdex, Neofordex, others
Hackensack Meridian Health, Karyopharm Therapeutics Inc
Multiple Myeloma
01/26
01/26
NCT06235567: Dextenza Versus Topical Steroid Eye Drops for Postoperative Management Following Corneal Crosslinking

Enrolling by invitation
1/2
20
US
Dextenza 0.4Mg Ophthalmic Insert, topical prednisolone acetate 1% (PredForte) eye drops
Maanasa Indaram, MD
Keratoconus
12/25
06/26
NCT05620901: DEXTENZA in Pediatric Patients Following Retinal Surgery or Laser Treatment Under Anesthesia

Recruiting
1
30
US
Dextenza 0.4Mg Ophthalmic Insert, Pred Forte
Lejla Vajzovic, MD, FASRS
Vitreoretinopathy, Coats' Disease, Exudative Retinopathy, Lattice Degeneration, Retinal Hole, Sickler's Syndrome, Retinal Detachment Rhegmatogenous, Retinal Detachment Exudative, Retinal Detachment Traction
04/25
04/25
ChiCTR2400079737: A Real-world Study of DEXTENZA® for the Treatment of Ocular Inflammation and Pain after Cataract Surgery

Completed
N/A
120
 
Dexamethasone Ophthalmic Insert
Boao Super Hospital; Shanghai AffaMed Therapeutics Co., Ltd., self-funding
Ocular inflammation and pain following ophthalmic surgery
 
 
Paxtrava (travoprost intracameral implant) / Ocular Therap
NCT05335122: A Study to Evaluate the Efficacy and Safety of OTX-TIC (Travoprost) Intracameral Implant for Patients With Open-angle Glaucoma (OAG) or Ocular Hypertension (OHT)

Completed
2
83
US
OTX-TIC low dose Travoprost Intracameral Implant, OTX-TIC high dose Travoprost Intracameral Implant, Durysta, Bimatoprost Intracameral Implant 10 µg
Ocular Therapeutix, Inc.
Open Angle Glaucoma, Ocular Hypertension
01/24
01/25
NCT04360174: CLN-0045: Safety, and Efficacy of OTX-TIC in Participants With Open Angle Glaucoma or Ocular Hypertension

Completed
1
19
US
OTX-TIC
Ocular Therapeutix, Inc.
Ocular Hypertension, Open Angle Glaucoma
05/21
05/21
The XU Study, NCT05835141: Rates and Risk Factors of Contact Between the OTX-TIC Intracameral Ocular Implant and Corneal Endothelium

Recruiting
N/A
100
US
OCT Imaging
University of Southern California
Corneal Endothelium
01/24
05/24
Axpaxli (intravitreal axitinib implant) / Ocular Therap
OTX-TKI-2023-AMD-301, NCT06223958: Study to Evaluate the Efficacy and Safety of Intravitreal OTX-TKI (Ocular Therapeutix) (Axitinib Implant) in Subjects With Neovascular Age-Related Macular Degeneration

Active, not recruiting
3
344
US, RoW
OTX-TKI (axitinib implant), Aflibercept
Ocular Therapeutix, Inc., Fortrea, Duke University
Neovascular Age-Related Macular Degeneration
04/26
09/27
OTX-TKI-2023-AMD-303, NCT06495918: Study to Evaluate the Efficacy and Safety of Intravitreal OTX-TKI (Axitinib Implant) in Subjects With Neovascular Age- Related Macular Degeneration

Active, not recruiting
3
825
US, RoW
OTX-TKI, Aflibercept
Ocular Therapeutix, Inc., Fortrea, Duke University
Neovascular Age-related Macular Degeneration
01/27
01/27
NCT03630315: CLN-0046: Treatment of AMD Subjects With OTX-TKI

Completed
1
29
RoW
OTX-TKI, Anti-VEGF, aflibercept, bevacizumab, ranibizumab
Ocular Therapeutix, Inc.
Neovascular Age-related Macular Degeneration
01/24
01/24
NCT04989699: Study Evaluating the Treatment of OTX-TKI for Subjects With Neovascular Age-related Macular Degeneration

Completed
1
21
US
OTX-TKI/Sham, Aflibercept/Sham, Eylea
Ocular Therapeutix, Inc.
Neovascular Age-Related Macular Degeneration
02/23
12/23
OTX-TKI-2022-101, NCT05695417: Study to Evaluate the Safety, Tolerability, and Efficacy of OTX-TKI in Subjects With Moderately Severe to Severe Non-proliferative Diabetic Retinopathy

Active, not recruiting
1
21
US
OTX-TKI, Sham
Ocular Therapeutix, Inc.
Non-proliferative Diabetic Retinopathy
01/24
12/24
dexamethasone intracanalicular insert (OTX-DED) / Ocular Therap
NCT05814757: OTX-DED for the Short-term Treatment of the Symptoms of Dry Eye Disease (DED)

Completed
2
100
US
OTX-DED, Controlled Insertion, Collagen Punctal Plug
Ocular Therapeutix, Inc.
Dry Eye Syndromes, Eye Diseases
05/24
05/24

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