St. Jude Children's Research Hospital 
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 6 Products   21 Diseases  6 Products   7 Trials   117 News 
6 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
humanised dinutuximab (Hu14.18K322A) / Essential Pharma
NCT01857934: Therapy for Children With Advanced Stage Neuroblastoma

Active, not recruiting
2
153
US
cyclophosphamide, Cytoxan(R), topotecan, Hycamtin(R), hu14.18K322A, humanized anti-GD2 antibody, monoclonal antibody, dinutuximab, peripheral blood stem cell harvest, PBSCH, surgical resection, cisplatin, Platinol-AQ(R), etoposide, VP16, Vepesid(R), Etopophos(R), doxorubicin, Adriamycin(R), vincristine, Oncovin(R), busulfan, Busulfex(R), melphalan, L-phenylalanine mustard, Phenylalanine mustard, L-PAM, L-sarcolysin, Alkeran(R), peripheral blood stem cell transplantation, PBSCT, natural killer cell infusion, NK cell infusion, radiation therapy, GM-CSF, sargramostim, Leukine(R), granulocyte macrophage colony stimulating factor, G-CSF, Granulocyte colony stimulating factor, Neupogen(R), Filgrastim, mesna, Mesnex(R), levetiracetam, Keppra, interleukin-2, IL-2, aldesleukin, Proleukin(R), Isotretinoin, 13-cis retinoic acid, CliniMACS, Cell Selection System
St. Jude Children's Research Hospital, Cookies for Kids' Cancer, CURE Childhood Cancer, Inc.
Neuroblastoma
10/21
12/24
CD123-CAR T cell therapy / St. Jude Children's Research Hospital
CATCHAML, NCT04318678: CD123-Directed Autologous T-Cell Therapy for Acute Myelogenous Leukemia

Recruiting
1
32
US
CD123-CAR T, CD123-CAR T cells, Cyclophosphamide, Cytoxan, Fludarabine, Fludara, Mesna, Rituximab, Rituxan
St. Jude Children's Research Hospital
AML/MDS, B-ALL, T-ALL, BPDCN
05/25
05/26
CD19-CAR.CD45RA- negative T-cells / St. Jude Children's Research Hospital
NCT04881240: Study of CD19-directed Allogeneic Memory T-cell Therapy for Relapsed/Refractory CD19+ Leukemia

Recruiting
1
60
US
CD19-CAR(Mem) T-cells, Cyclophosphamide, Cytoxan, Fludarabine, Fludara, Mesna, Mesnex, CliniMACS, Leukapheresis
St. Jude Children's Research Hospital
Acute Lymphoblastic Leukemia, in Relapse, Acute Lymphoblastic Leukemia, Refractory, Pediatric ALL
06/26
06/27
B7-H3 CAR-T / St. Jude Children's Research Hospital
NCT04897321: B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

Recruiting
1
32
US
Fludarabine, Fludara, Cyclophosphamide, Cytoxan, MESNA, Mesnex, B7-H3 CAR T cells, CAR T- cell infusion
St. Jude Children's Research Hospital
Pediatric Solid Tumor, Osteosarcoma, Rhabdomyosarcoma, Neuroblastoma, Ewing Sarcoma, Wilms Tumor, Adrenocortical Cancer, Desmoplastic Small Round Cell Tumor, Germ Cell Cancer, Rhabdoid Tumor, Clear Cell Sarcoma, Hepatoblastoma, Melanoma, Carcinoma, Malignant Peripheral Nerve Sheath Tumors, Soft Tissue Sarcoma
03/26
03/27
NCT05835687: Loc3CAR: Locoregional Delivery of B7-H3-CAR T Cells for Pediatric Patients With Primary CNS Tumors

Recruiting
1
36
US
B7-H3-CAR T cells
St. Jude Children's Research Hospital
Central Nervous System Neoplasms, Atypical Teratoid/Rhabdoid Tumor, Diffuse Midline Glioma, H3 K27M-Mutant, Ependymoma, High Grade Glioma, Glioblastoma, Medulloblastoma
03/28
03/28
SJCAR19 / St. Jude Children's Research Hospital
NCT03573700: Evaluation of CD19-Specific CAR Engineered Autologous T-Cells for Treatment of Relapsed/Refractory CD19+ Acute Lymphoblastic Leukemia

Active, not recruiting
1/2
24
US
Cyclophosphamide, Cytoxan, Fludarabine, Fludara, Mesna, Mesnex, CliniMACS, CD19- specific CAR engineered autologous T-cells (SJCAR19 product)
St. Jude Children's Research Hospital
Acute Lymphoblastic Leukemia, in Relapse, Acute Lymphoblastic Leukemia, Refractory
07/23
07/25

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