GRIN Therap 
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9 Trials

   

Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
radiprodil (RGH-896) / AbbVie, GRIN Therap
2005-001201-25: Phase II placebo-controlled study to evaluate the efficacy, safety and tolerability of RGH-896 in patients with pain due to diabetic sensorimotor peripheral neuropathy

Ongoing
2
45
Europe
RGH-896,
Gedeon Richter Ltd
Neuropathic pain in patients with diabetic peripheral neuropathy
 
 
RAD-GRIN-201, NCT06392009: Astroscape: A Study of Radiprodil on Safety, Tolerability, Pharmacokinetics, and Effect on Seizures and Behavioral Symptoms in Patients With TSC or FCD Type II

Recruiting
1/2
30
Europe, Canada, RoW
Radiprodil
GRIN Therapeutics, Inc.
Tuberous Sclerosis Complex, Focal Cortical Dysplasia
07/25
07/26
NCT05818943 / 2022-000317-14: Honeycomb: Evaluation of Radiprodil in Children with GRIN-related Disorder

Active, not recruiting
1
24
Europe, Canada, US, RoW
Radiprodil
GRIN Therapeutics, Inc., GRIN Therapeutics, Inc.
GRIN-related Disorders
11/26
11/26
ACTRN12624000102572: An Open-label, Randomised, Crossover Study to Assess Fasted Versus Fed Bioavailability of Radiprodil in Healthy Adults

Completed
1
18
 
GRIN Therapeutics, Inc., GRIN Therapeutics, Inc.
glutamate receptor ionotropic N-methyl-D-aspartate (GRIN) related disorder - neurodevelopmental syndromes
 
 
ACTRN12624000878572: A Phase 1 Study to Evaluate the Effect of Multiple Doses of Rabeprazole on the Pharmacokinetics of a Single Dose of Radiprodil in Healthy Adult Participants

Completed
1
18
 
GRIN Therapeutics, Inc., GRIN Therapeutics, Inc.
Malformations of Cortical Development
 
 
ACTRN12624001366549: An Open-label, 2 Part, Study to Assess the Pharmacokinetics of a Spray Dried Dispersion Formulation of Radiprodil Under Fasted and Fed Conditions in Healthy Adult Subjects: Part A

Completed
1
18
 
GRIN Therapeutics, Inc., GRIN Therapeutics, Inc.
Glutamate receptor ionotropic N-methyl-D-aspartate (GRIN) related disorder - neurodevelopmental syndromes
 
 
ACTRN12624001440516: An Open-label, 2 Part, Study to Assess the Pharmacokinetics of a Spray Dried Dispersion Formulation of Radiprodil Under Fasted and Fed Conditions in Healthy Adult Subjects: Part B

Completed
1
18
 
GRIN Therapeutics, Inc., GRIN Therapeutics, Inc.
Glutamate receptor ionotropic N-methyl-D-aspartate (GRIN) related disorder - neurodevelopmental syndromes
 
 
NCT06965881: Study to Evaluate the Pharmacokinetics and Safety Effects Following Coadministration of Carbamazepine or Itraconazole With Radiprodil in Healthy Adults

Recruiting
1
36
RoW
Radiprodil with Carbamazepine, Radiprodil with Itraconazole
GRIN Therapeutics, Inc., Avance Clinical Pty Ltd.
Tuberous Sclerosis Complex (TSC), Focal Cortical Dysplasia, Other Neurological Disorders
08/25
09/25
NCT06975605: Phase 1, Open-label, Drug-drug Interaction Study to Assess Effect Between Radiprodil and the Co-administered Drugs.

Active, not recruiting
1
18
RoW
Radiprodil + co-administered drugs
GRIN Therapeutics, Inc., Avance Clinical Pty Ltd.
Tuberous Sclerosis Complex (TSC), Focal Cortical Dysplasia, Other Neurological Disorders
07/25
08/25
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
radiprodil (RGH-896) / AbbVie, GRIN Therap
2005-001201-25: Phase II placebo-controlled study to evaluate the efficacy, safety and tolerability of RGH-896 in patients with pain due to diabetic sensorimotor peripheral neuropathy

Ongoing
2
45
Europe
RGH-896,
Gedeon Richter Ltd
Neuropathic pain in patients with diabetic peripheral neuropathy
 
 
RAD-GRIN-201, NCT06392009: Astroscape: A Study of Radiprodil on Safety, Tolerability, Pharmacokinetics, and Effect on Seizures and Behavioral Symptoms in Patients With TSC or FCD Type II

Recruiting
1/2
30
Europe, Canada, RoW
Radiprodil
GRIN Therapeutics, Inc.
Tuberous Sclerosis Complex, Focal Cortical Dysplasia
07/25
07/26
NCT05818943 / 2022-000317-14: Honeycomb: Evaluation of Radiprodil in Children with GRIN-related Disorder

Active, not recruiting
1
24
Europe, Canada, US, RoW
Radiprodil
GRIN Therapeutics, Inc., GRIN Therapeutics, Inc.
GRIN-related Disorders
11/26
11/26
ACTRN12624000102572: An Open-label, Randomised, Crossover Study to Assess Fasted Versus Fed Bioavailability of Radiprodil in Healthy Adults

Completed
1
18
 
GRIN Therapeutics, Inc., GRIN Therapeutics, Inc.
glutamate receptor ionotropic N-methyl-D-aspartate (GRIN) related disorder - neurodevelopmental syndromes
 
 
ACTRN12624000878572: A Phase 1 Study to Evaluate the Effect of Multiple Doses of Rabeprazole on the Pharmacokinetics of a Single Dose of Radiprodil in Healthy Adult Participants

Completed
1
18
 
GRIN Therapeutics, Inc., GRIN Therapeutics, Inc.
Malformations of Cortical Development
 
 
ACTRN12624001366549: An Open-label, 2 Part, Study to Assess the Pharmacokinetics of a Spray Dried Dispersion Formulation of Radiprodil Under Fasted and Fed Conditions in Healthy Adult Subjects: Part A

Completed
1
18
 
GRIN Therapeutics, Inc., GRIN Therapeutics, Inc.
Glutamate receptor ionotropic N-methyl-D-aspartate (GRIN) related disorder - neurodevelopmental syndromes
 
 
ACTRN12624001440516: An Open-label, 2 Part, Study to Assess the Pharmacokinetics of a Spray Dried Dispersion Formulation of Radiprodil Under Fasted and Fed Conditions in Healthy Adult Subjects: Part B

Completed
1
18
 
GRIN Therapeutics, Inc., GRIN Therapeutics, Inc.
Glutamate receptor ionotropic N-methyl-D-aspartate (GRIN) related disorder - neurodevelopmental syndromes
 
 
NCT06965881: Study to Evaluate the Pharmacokinetics and Safety Effects Following Coadministration of Carbamazepine or Itraconazole With Radiprodil in Healthy Adults

Recruiting
1
36
RoW
Radiprodil with Carbamazepine, Radiprodil with Itraconazole
GRIN Therapeutics, Inc., Avance Clinical Pty Ltd.
Tuberous Sclerosis Complex (TSC), Focal Cortical Dysplasia, Other Neurological Disorders
08/25
09/25
NCT06975605: Phase 1, Open-label, Drug-drug Interaction Study to Assess Effect Between Radiprodil and the Co-administered Drugs.

Active, not recruiting
1
18
RoW
Radiprodil + co-administered drugs
GRIN Therapeutics, Inc., Avance Clinical Pty Ltd.
Tuberous Sclerosis Complex (TSC), Focal Cortical Dysplasia, Other Neurological Disorders
07/25
08/25

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