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- gp130 modulator / CarthroniX, CX-011 / CarthroniX
Novel Small Molecule Modulator of the gp130 Receptor Shows Dose-dependent Therapeutic Efficacy in a Canine Model of Osteoarthritis (Virtual Poster Hall) - Sep 17, 2022 - Abstract #ACRConvergence2022ACR_CONVERGENCE_2264;
We have shown that the high 10 μg and medium 1 μg dose groups prevent some of the most important pathophysiological changes promoting osteoarthritis progression. Notably, bone remodeling and shape change is prevented.