Jiangsu Hengrui Pharma 
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 196 Products   52 Diseases   196 Products   3529 Trials   15381 News 


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  • ||||||||||  Irene (pyrotinib) / Jiangsu Hengrui Pharma, Enhertu (fam-trastuzumab deruxtecan-nxki) / Daiichi Sankyo, AstraZeneca
    Review, Journal:  Advances and Future Perspectives of HER2 Mutations in Non-Small Lung Cancer (NSCLC), Especially in China. (Pubmed Central) -  Jun 5, 2025   
    In general, the incidence of HER2-mutated NSCLC in the Chinese population seems to be higher than the world average, and there is a large number of missed HER2-mutated NSCLC patients in China. In this field, ADCs and novel TKIs are being developed and researched in spurts, and new drugs are moving from back-line therapy to front-line therapy, and from single-drug regimens to combination regimens.
  • ||||||||||  Kailimei (satricabtagene autoleucel) / CARsgen
    Enrollment closed, Trial primary completion date:  CT041-ST-01: Study to Evaluate the Efficacy, Safety and Pharmacokinetics of CT041 Autologous CAR T-cell Injection (clinicaltrials.gov) -  Jun 5, 2025   
    P1/2,  N=192, Active, not recruiting, 
    The combination of blinatumomab, olverembatinib, and concurrent intrathecal chemotherapy may be an effective treatment strategy for CML progression, particularly in cases with CNS involvement. Recruiting --> Active, not recruiting | Trial primary completion date: Jun 2024 --> Oct 2024
  • ||||||||||  HS-10502 / Jiangsu Hansoh Pharma
    Enrollment open:  HS-10502 Combination Treatment in Patients With Advanced Solid Tumors (clinicaltrials.gov) -  Jun 4, 2025   
    P1,  N=157, Recruiting, 
    Recruiting --> Active, not recruiting | Trial primary completion date: Jun 2024 --> Oct 2024 Not yet recruiting --> Recruiting
  • ||||||||||  AiTan (rivoceranib) / HLB Bio Group, Lysodren (mitotane) / Perrigo Company
    Trial completion date:  Phase II Study of PD-1 Inhibitor Combined With Apatinib and Mitotane in the Treatment of Advanced Adrenal Cortical Carcinoma (clinicaltrials.gov) -  Jun 3, 2025   
    P2,  N=28, Recruiting, 
    The combination of remimazolam tosilate and esketamine effectively reduces postoperative psychiatric symptoms, enhances hemodynamic stability, and improves recovery quality, making it a viable anesthetic strategy for ambulatory surgery. Trial completion date: Dec 2030 --> Dec 2031
  • ||||||||||  vunakizumab (SHR-1314) / Jiangsu Hengrui Pharma
    Journal:  First successful treatment of epidermolytic Ichthyosis with Vunakizumab: A Case Report. (Pubmed Central) -  Jun 2, 2025   
    After a three-month treatment with Vunakizumab, symptoms alleviated significantly and inflammatory factor levels normalized. This not only shows the great potential of Vunakizumab in treating ichthyosis but also paves the way for further research on anti-IL-17A therapies for skin cornification disorders, offering treatment options for ichthyosis patients.
  • ||||||||||  ivarmacitinib (SHR0302) / Jiangsu Hengrui Pharma, Arcutis
    EFFICACY OF IVARMACITINIB IN BIOLOGICAL DMARDS-NA () -  May 28, 2025 - Abstract #EULAR2025EULAR_3953;    
    P3
    These findings highlight the potential of vunakizumab as an effective treatment option for AS patients, regardless of gender. Ivarmacitinib effectively reduces disease activity and improves health-related quality of life in bDMARDs-na
  • ||||||||||  Erbitux (cetuximab) / Eli Lilly, AiRuiKa (camrelizumab) / HLB Bio Group
    Trial completion date, Trial primary completion date:  Camrelizumab in Combination With Cetuximab and Chemotherapy for Relapsed/Metastatic HNSCC Patients (clinicaltrials.gov) -  May 27, 2025   
    P2,  N=40, Recruiting, 
    Active, not recruiting --> Completed | Trial primary completion date: Dec 2023 --> Sep 2024 Trial completion date: Mar 2025 --> Aug 2025 | Trial primary completion date: Dec 2024 --> Jun 2025
  • ||||||||||  Review, Journal:  The Importance of Timing in Immunotherapy: A Systematic Review. (Pubmed Central) -  May 26, 2025   
    These results suggest that the timing of immunotherapy administration may significantly impact treatment efficacy, potentially due to interactions with circadian rhythms. Further research is needed to establish standardized guidelines for optimizing infusion timing to enhance patient outcomes.
  • ||||||||||  trastuzumab rezetecan (SHR-A1811) / Jiangsu Hengrui Pharma, AiRuiEn (rezvilutamide) / Jiangsu Hengrui Pharma, tizetatug rezetecan (SHR-A1921) / Jiangsu Hengrui Pharma
    Trial completion date, Trial primary completion date:  A Phase II Study of Advanced Salivary Gland Carcinoma Based on Molecular Typing (clinicaltrials.gov) -  May 23, 2025   
    P2,  N=88, Recruiting, 
    We also suggest that pyrotinib combined with vinorelbine has a therapeutic potential. Trial completion date: Sep 2026 --> Dec 2026 | Trial primary completion date: Sep 2025 --> Dec 2025
  • ||||||||||  ribupatide oral (HRS9531 tablet) / Kailera Therapeutics
    Trial completion:  A Study of Single and Multiple Doses HRS9531 Tablets in Healthy Subjects (clinicaltrials.gov) -  May 21, 2025   
    P1,  N=72, Completed, 
    These findings suggest that the peptide-based radiotracer [68Ga]Ga-DOTA-WC8 represents a promising tool for accurately monitoring of HER2 expression after treatment with HER2-targeting drugs. Recruiting --> Completed