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  • ||||||||||  tacrolimus / Generic mfg., meropenem / Generic mfg., Daewon Pharmaceutical
    [VIRTUAL] Case Study: Kidney Transplant Patient with COVID-19: Impact of Viral Infection on Background Cell-Free DNA in a Donor-Derived Cell-Free DNA Rejection Assay (On-Demand) -  Oct 11, 2020 - Abstract #KIDNEYWEEK2020KIDNEY_WEEK_1470;    
    Tacrolimus was discontinued on hospital d10 and she continued prednisone at 5 mg/d...Discussion In this case, infection with the SARS-CoV-2 virus was associated with a very elevated background cfDNA level, likely due to cellular apoptosis due to the immune process and/or tissue ischemia due to sepsis-associated hypoperfusion. Although this patient was not known to have active rejection of her allograft, the very high background levels complicate the interpretation of results, especially when donor fraction were reported.
  • ||||||||||  Actemra IV (tocilizumab) / Roche, JW Pharma
    [VIRTUAL] COVID-19 and Kidney Transplant Outcomes (On-Demand) -  Oct 11, 2020 - Abstract #KIDNEYWEEK2020KIDNEY_WEEK_1395;    
    Differing outcomes may be related to small number of cases, potentially varying acuities of illness and follow up periods. Given that cytokine storm occurs late in the course of COVID-19, it is plausible that mortality may increase in studies with short follow up.
  • ||||||||||  Vyrologix (leronlimab) / CytoDyn, Vyera Pharma
    #leronlimab $cydy (Twitter) -  Sep 21, 2020