- |||||||||| Sputnik-V (Gam-COVID-Vac Lyo) / Gamaleya Research Institute
Approve Sputnik V now (Twitter) - Sep 3, 2021
- |||||||||| Vaxzevria (ChAdOx1-S recombinant) / Oxford Biomedica, Emergent Biosolutions, Jenner Institute, Vaccitech, AstraZeneca, University of Oxford, Sputnik-V (Gam-COVID-Vac Lyo) / Gamaleya Research Institute
Clinical, Real-world evidence: Massive real world study in Bahrain on effect of 4 vaccines: SinoPharm, Sputnik V, Covishield (Astra Zeneca), Pfizer— before & during delta variant, by @DrSidMukherjee & colleagues. 1 million residents of 1.5 million vaccinated. All 4 vaccines showed high efficacy. #VaccinesWork (Twitter) - Aug 26, 2021
- |||||||||| Vaxzevria (ChAdOx1-S recombinant) / Oxford Biomedica, Emergent Biosolutions, Jenner Institute, Vaccitech, AstraZeneca, University of Oxford
Journal: Locally harvested Covid-19 convalescent plasma could probably help combat the geographically determined SARS-CoV-2 viral variants. (Pubmed Central) - Aug 22, 2021 However, there is a rising need for the efficacy of the vaccines to be proven against the "SARS-CoV-2 viral variants." Also, human plasma is polyclonal in nature with an inherent propensity to identify multiple epitopes of either an antigen or pathogen. With this context in mind, the researchers hypothesize that using COVID-19 convalescent plasma [CCP] harvested from the locally recovered individuals [i.e. potential CCP donors] may be particularly beneficial in combating not only the founder SARS-CoV-2 virus but also the geographically confined SARS-CoV-2 variants among the regionally affected COVID-19 patients.
- |||||||||| Covilo (BBIBP-CorV) / Wuhan Institute of Virology, Sinopharm, Vaxzevria (ChAdOx1-S recombinant) / University of Oxford, Emergent Biosolutions, Jenner Institute, Vaccitech, AstraZeneca
Trial completion: Study to Evaluate the Immunogenicity and Safety of Heterologous SARS-CoV-2 Vaccine Schemes (clinicaltrials.gov) - Aug 20, 2021 P2, N=192, Completed, With this context in mind, the researchers hypothesize that using COVID-19 convalescent plasma [CCP] harvested from the locally recovered individuals [i.e. potential CCP donors] may be particularly beneficial in combating not only the founder SARS-CoV-2 virus but also the geographically confined SARS-CoV-2 variants among the regionally affected COVID-19 patients. Recruiting --> Completed
- |||||||||| Sputnik-V (Gam-COVID-Vac Lyo) / Gamaleya Research Institute
Journal: Neutralizing activity of Sputnik V vaccine sera against SARS-CoV-2 variants. (Pubmed Central) - Aug 11, 2021 The same set of sera efficiently neutralize S from B.1.1.7 and exhibit only moderately reduced activity against S carrying the E484K substitution alone. Taken together, our data suggest that control of some emergent SARS-CoV-2 variants may benefit from updated vaccines.
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