- |||||||||| ByFavo (remimazolam) / PAION, Cosmo Pharma, Mundipharma, Pharmascience, Eagle Pharma
Journal: Intubated or rigid bronchoscopy under high-flow oxygenation and deep sedation without ventilator or anesthesiologist: A report on a new technique. (Pubmed Central) - Sep 10, 2024
Finally, either an uncuffed endotracheal tube (Case 1) or a rigid bronchoscope (Case 2) was inserted, and advanced bronchoscopic procedures, such as cryobiopsy and stent insertion, were successfully performed without a ventilator or an anesthesiologist. Our novel technique is expected to facilitate the easier and adequate performance of advanced high-level bronchoscopic procedures by pulmonologists, even in resource-limited settings.
- |||||||||| ByFavo (remimazolam) / PAION, Cosmo Pharma, Mundipharma, Pharmascience, Eagle Pharma
Review, Journal: Remimazolam in intensive care unit: Potential applications and considerations. (Pubmed Central) - Sep 10, 2024
Its cost is comparable to that of current medications. Further research on its long-term safety in the ICU and its broader application and incorporation into routine use is necessary.
- |||||||||| ByFavo (remimazolam) / PAION, Cosmo Pharma, Mundipharma, Pharmascience, Eagle Pharma
Journal: Hiccups during general anesthesia with remimazolam. (Pubmed Central) - Sep 4, 2024
Further research on its long-term safety in the ICU and its broader application and incorporation into routine use is necessary. No abstract available
- |||||||||| ByFavo (remimazolam) / PAION, Cosmo Pharma, Mundipharma, Pharmascience, Eagle Pharma
Trial completion date, Trial primary completion date: Esketamine vs Remimazolam for Postoperative Sleep Disturbance and Anxiety (clinicaltrials.gov) - Sep 4, 2024
P=N/A, N=300, Recruiting,
No abstract available Trial completion date: Jul 2024 --> Dec 2024 | Trial primary completion date: Jun 2024 --> Nov 2024
- |||||||||| ByFavo (remimazolam) / PAION, Cosmo Pharma, Mundipharma, Pharmascience, Eagle Pharma
Trial completion date, Trial primary completion date: Esketamine Combined With Remimazolam on Postoperative Sleep Disturbance and Anxiety in Patients (clinicaltrials.gov) - Sep 4, 2024
P=N/A, N=400, Recruiting,
Trial completion date: Jul 2024 --> Dec 2024 | Trial primary completion date: Jun 2024 --> Nov 2024 Trial completion date: Jun 2024 --> Dec 2024 | Trial primary completion date: May 2024 --> Nov 2024
- |||||||||| ByFavo (remimazolam) / PAION, Cosmo Pharma, Mundipharma, Pharmascience, Eagle Pharma
Review, Journal: Remimazolam Use in Cardiac Anesthesia: A Narrative Review. (Pubmed Central) - Sep 2, 2024
This narrative review aims to summarize and analyze the available literature on the effects of remimazolam use in cardiac surgical patients, including its effects on hemodynamics, safety in patients with baseline myocardial dysfunction, and impact on postoperative management including time to emergence and extubation. Finally, there is discussion regarding potential drawbacks of adopting remimazolam as a routine anesthetic for cardiac surgery.
- |||||||||| ByFavo (remimazolam) / PAION, Cosmo Pharma, Mundipharma, Pharmascience, Eagle Pharma
Clinical, Retrospective data, Review, Journal: Comparison of the recovery quality between remimazolam and propofol after general anesthesia: systematic review and a meta-analysis of randomized controlled trials. (Pubmed Central) - Sep 1, 2024
Our analysis showed that the recovery quality of the remimazolam group after general anaesthesia was similar to propofol group, while the incidence of adverse events was low in remimazolam group. As a potential anesthetic, remimazolam can be used in place of propofol for surgical general anesthesia.
- |||||||||| ByFavo (remimazolam) / PAION, Cosmo Pharma, Mundipharma, Pharmascience, Eagle Pharma
Retrospective data, Journal, Surgery: Retrospective comparison of the effects of remimazolam and dexmedetomidine on postoperative delirium in elderly patients undergoing orthopedic surgery of the lower extremities under spinal anesthesia. (Pubmed Central) - Aug 26, 2024
Importantly, the concomitant use of 1 ?g/kg of fentanyl does not increase the risk of adverse effects such as hypotension, respiratory depression. Compared with dexmedetomidine, remimazolam infusion may be associated with a higher risk of POD in elderly patients undergoing orthopedic surgery of the lower extremities under spinal anesthesia.
- |||||||||| ByFavo (remimazolam) / PAION, Cosmo Pharma, Mundipharma, Pharmascience, Eagle Pharma
Clinical, Journal, Combination therapy, Surgery: The effects of remimazolam in combination with estazolam on postoperative hemodynamics and pain intensity in patients undergoing laparoscopic gastrointestinal surgery. (Pubmed Central) - Aug 26, 2024
The combination of remimazolam and estazolam effectively stabilized hemodynamics, reduced anxiety levels, and alleviated pain intensity after laparoscopic gastrointestinal surgery. These findings suggest that this combination therapy has the potential to improve surgical outcomes and patient comfort.
- |||||||||| ByFavo (remimazolam) / PAION, Cosmo Pharma, Mundipharma, Pharmascience, Eagle Pharma
Journal: Remimazolam: A New Drug Looking For a Niche. (Pubmed Central) - Aug 22, 2024
In conclusion, our study revealed that the neuronal HIPK2-HDAC3 axis in the ischemic focus regulates mitochondrial fragmentation to balance inflammation stress reservoir to participate in anxiety susceptibility after stroke. No abstract available
- |||||||||| ByFavo (remimazolam) / PAION, Cosmo Pharma, Mundipharma, Pharmascience, Eagle Pharma
Review, Journal: Remimazolam-Update on basic pharmacologic principles and clinical potential (Pubmed Central) - Aug 19, 2024
Remimazolam is also now approved in the EU and the market launch in Germany is expected in the not too distant future. This is therefore a good point in time to summarize the current evidence for various areas of application, including general anesthesia, sedation and intensive care medicine as well as different dosing schemes.
- |||||||||| ByFavo (remimazolam) / PAION, Cosmo Pharma, Mundipharma, Pharmascience, Eagle Pharma
Journal: Unveiling the impact of airways: A comparative analysis of oropharyngeal and nasopharyngeal airways in painless fiberoptic bronchoscopy. (Pubmed Central) - Aug 19, 2024
This is therefore a good point in time to summarize the current evidence for various areas of application, including general anesthesia, sedation and intensive care medicine as well as different dosing schemes. This study compared the efficacy of oropharyngeal airways (OA) and nasopharyngeal airways (NA) in maintaining oxygenation during painless fiberoptic bronchoscopy (PFB) in patients sedated with remimazolam besylate...Following flumazenil anesthesia reversal, nearly 97
- |||||||||| ByFavo (remimazolam) / PAION, Cosmo Pharma, Mundipharma, Pharmascience, Eagle Pharma
Review, Journal: The Role of Intravenous Anesthetics for Neuro: Protection or Toxicity? (Pubmed Central) - Aug 17, 2024
The role of intravenous anesthetics for neuro on both sides of protection or toxicity has been rarely summarized. Considering the mentioned above, this work aims to offer a comprehensive understanding of the underlying mechanisms involved both in the central nerve system (CNS) and the peripheral nerve system (PNS) and provide valuable insights into the potential safety and risk associated with the clinical use of intravenous anesthetics.
- |||||||||| ByFavo (remimazolam) / PAION, Cosmo Pharma, Mundipharma, Pharmascience, Eagle Pharma
Observational data, Retrospective data, Journal: Remimazolam anesthesia in pediatric patients undergoing cardiac catheterization for congenital heart disease: a retrospective observational study. (Pubmed Central) - Aug 17, 2024
Considering the mentioned above, this work aims to offer a comprehensive understanding of the underlying mechanisms involved both in the central nerve system (CNS) and the peripheral nerve system (PNS) and provide valuable insights into the potential safety and risk associated with the clinical use of intravenous anesthetics. Remimazolam is a good alternative anesthetic agent for pediatric patients undergoing cardiac catheterization for CHD.
- |||||||||| ByFavo (remimazolam) / PAION, Cosmo Pharma, Mundipharma, Pharmascience, Eagle Pharma
Journal: Promise of Remimazolam in Pediatric Emergence Delirium. (Pubmed Central) - Aug 13, 2024
Our findings suggest that remimazolam, an ultra-short-acting benzodiazepine, is feasible for the transcarotid TAVR procedure due to its minimal circulatory impact and ability to facilitate rapid and reliable arousal. No abstract available
- |||||||||| ByFavo (remimazolam) / PAION, Cosmo Pharma, Mundipharma, Pharmascience, Eagle Pharma
Trial completion date, Trial primary completion date, Surgery: Comparison of Hemodynamic Stability During Anesthesia Using Remimazolam and Sevoflurane in Minimally Invasive AVR (clinicaltrials.gov) - Aug 11, 2024
P=N/A, N=52, Recruiting,
Initiation date: Jul 2024 --> Jan 2025 Trial completion date: Jun 2024 --> Jun 2025 | Trial primary completion date: Jun 2024 --> Jun 2025
- |||||||||| ByFavo (remimazolam) / PAION, Cosmo Pharma, Mundipharma, Pharmascience, Eagle Pharma
Enrollment open: Binaural Sound for Remimazolam Maintenance (clinicaltrials.gov) - Aug 9, 2024
P=N/A, N=72, Recruiting,
Trial primary completion date: Jun 2024 --> Sep 2024 Not yet recruiting --> Recruiting
- |||||||||| ByFavo (remimazolam) / PAION, Cosmo Pharma, Mundipharma, Pharmascience, Eagle Pharma
Clinical, Journal: Effect of remimazolam and propofol anesthesia on autonomic nerve activities during Le Fort I osteotomy under general anesthesia: blinded randomized clinical trial. (Pubmed Central) - Aug 9, 2024
Evaluation of autonomic nerve activity in comparison with baseline during down-fracture showed a significant increase in BPV LF (P < 0.001), an increasing trend in HRV LF/HF in Group P, and an increasing trend in HRV HF in Group R. There were no significant differences in HR or SBP between the two groups. During down-fracture of Le Fort I osteotomy, sympathetic nerve activity was predominant with propofol anesthesia, and parasympathetic nerve activity was predominant with remimazolam anesthesia.
- |||||||||| ByFavo (remimazolam) / PAION, Cosmo Pharma, Mundipharma, Pharmascience, Eagle Pharma
Remimazolam for Anesthetic of a Medically Complex Female with Rett Syndrome (Exhibit Hall) - Aug 6, 2024 - Abstract #ASA2024ASA_5823;
She tolerated the procedure well and was discharged to home following the procedure.This is presented to demonstrate the efficacy of remimazolam in Rett Syndrome. Remimazolam's pharmacokinetics are ideal for these patients with frequent post-operative respiratory complications after anesthesia.
- |||||||||| ByFavo (remimazolam) / PAION, Cosmo Pharma, Mundipharma, Pharmascience, Eagle Pharma
Remimazolam infusion for sedation in peripheral nerve blocks (Exhibit Hall) - Aug 6, 2024 - Abstract #ASA2024ASA_5495;
He wanted to be able to discuss his treatment course with his surgical team on afternoon rounds and therefore did not want to be heavily sedated for the procedure which was required for nerve blocks in the past. Utilizing a remimazolam infusion, we were able to effectively sedate this patient for the procedure, while allowing him to have important discussions with his care team coherently.
- |||||||||| ByFavo (remimazolam) / PAION, Cosmo Pharma, Mundipharma, Pharmascience, Eagle Pharma
Unexpected therapeutic effects of esketamine in patients with Yang-deficiency constitution of TCM:a Case report (Exhibit Hall) - Aug 6, 2024 - Abstract #ASA2024ASA_4675;
An 81-year-old man with Yang-deficiency constitution underwent radical resection of rectal cancer under general anesthesia with remimazolam and esketamine...The patient's mood was stable until discharge. This report provides a new perspective and possible application of esketamine in the field of traditional Chinese medicine (TCM) constitution treatment through the emotional venting and psychological symptoms improvement of patients after receiving esketamine anesthesia.
- |||||||||| ByFavo (remimazolam) / PAION, Cosmo Pharma, Mundipharma, Pharmascience, Eagle Pharma
The Path to Recanalization: Anesthetic Management of Severe SVC Syndrome (Exhibit Hall) - Aug 6, 2024 - Abstract #ASA2024ASA_4580;
Left thoracentesis yielded 1.3 liters prior to induction with remimazolam and intubation at 45-degrees. This case highlights strategies used to manage patients with complex cardiorespiratory physiology secondary to SVC syndrome.
- |||||||||| ByFavo (remimazolam) / PAION, Cosmo Pharma, Mundipharma, Pharmascience, Eagle Pharma
Remimazolam sedation during MRI in a toddler with COVID, high fever, and seizures (Exhibit Hall) - Aug 6, 2024 - Abstract #ASA2024ASA_4411;
Remimazolam is an ester metabolized benzodiazepine with pharmacokinetic properties similar to those of remifentanil.1 A remimazolam infusion was used as the primary agent for sedation in a 9-month-old, 11.2 kg child with a COVID-19 infection with respiratory involvement, fever (106oC), and seizures during MR imaging. Following two boluses of dexmedetomidine (0.5
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