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2 Products |  |
3 Diseases | | 2 Products |
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0 Trials |  |
40 News |  |
- || promethazine / hydrocodone / acetaminophen (CL-108) / Daiichi Sankyo, Charleston Labs
Clinical, Journal: Prevention of Opioid-Induced Nausea and Vomiting During Treatment of Moderate to Severe Acute Pain: A Randomized Placebo-Controlled Trial Comparing CL-108 (Hydrocodone 7.5 mg/Acetaminophen 325 mg/Rapid-Release, Low-Dose Promethazine 12.5 mg) with Conventional Hydrocodone 7.5 mg/Acetaminophen 325 mg. (Pubmed Central) - Sep 17, 2020
There were no unexpected or serious adverse events. CL-108 is a safe and effective combination analgesic/antiemetic for the prevention of OINV during treatment of moderate to severe acute pain.
- || promethazine/sumatriptan (CL-H1T) / Charleston Labs
Looking forward to publishing the full data. @Dr_BDSmith https://t.co/OClh1TPyM1 (Twitter) - Jul 29, 2020
- |||| promethazine/sumatriptan (CL-H1T) / Charleston Labs
Trial completion: A Study to Assess the Efficacy and Safety of Oral CL-H1T in the Treatment of Acute Migraine Pain (clinicaltrials.gov) - Nov 11, 2019
P2, N=475, Completed, Sponsor: Charleston Laboratories, Inc
CL-108 is a safe and effective combination analgesic/antiemetic for the prevention of OINV during treatment of moderate to severe acute pain. Recruiting --> Completed
- promethazine / hydrocodone / acetaminophen (CL-108) / Daiichi Sankyo, Charleston Laboratories
A Rare Case of Gastric Sarcoidosis (Exhibit Halls 3 and 4 (Street Level)) - Aug 8, 2019 - Abstract #ACG2019ACG_2261;
Labs showed hemoglobin 8.9, MCV 57, iron level 11, Na 138, Cl 108, and CO2 20...The patient was initially started on prednisone 40 mg daily tapering dose and had near immediate resolution of symptoms with increase in weight...For recurrence of symptoms, surveillance endoscopy is warranted to examine extent of disease. As in our patient, there is excellent response to glucocorticoid treatment and patients should be monitored clinically with tapering doses.
- ||||| promethazine/sumatriptan (CL-H1T) / Charleston Labs
New P2 trial: A Study to Assess the Efficacy and Safety of Oral CL-H1T in the Treatment of Acute Migraine Pain (clinicaltrials.gov) - Mar 18, 2019
P2, N=400, Recruiting, Sponsor: Charleston Laboratories, Inc
- ||||||| Hydexor (promethazine/hydrocodone/acetaminophen) / Daiichi Sankyo, Charleston Labs
Trial completion, Surgery: A Controlled Study to Determine the Efficacy and Safety of CL-108 5 mg for Acute Pain and the Prevention of OINV (clinicaltrials.gov) - Jan 3, 2019
P3, N=349, Completed, Sponsor: Charleston Laboratories, Inc
As in our patient, there is excellent response to glucocorticoid treatment and patients should be monitored clinically with tapering doses. Active, not recruiting --> Completed
- ||||||| Hydexor (promethazine/hydrocodone/acetaminophen) / Daiichi Sankyo, Charleston Labs
Trial completion, Enrollment change: Phase III Study of the Safety and Efficacy of Cl-108 in the Treatment of Moderate to Severe Pain (clinicaltrials.gov) - Nov 3, 2016
P3, N=460, Completed, Sponsor: Charleston Laboratories, Inc
Active, not recruiting --> Completed Recruiting --> Completed | N=810 --> 460
- | Hydexor (promethazine/hydrocodone/acetaminophen) / Daiichi Sankyo, Charleston Labs
New P1 trial: A Study in Opioid-Experienced, Non-Dependent Recreational Drug Users to Determine the Abuse Potential and Safety of CL-108 Tablets Administered Via the Oral Route (clinicaltrials.gov) - Mar 18, 2016
P1, N=34, Completed, Sponsor: Charleston Laboratories, Inc
- ||||||| Hydexor (promethazine/hydrocodone/acetaminophen) / Daiichi Sankyo, Charleston Labs
Trial completion, Trial primary completion date: A Multi-Center Actual-Use Study on the Safety of CL 108 for the Treatment of Moderate to Severe Acute Pain Associated With Osteoarthritis of the Knee or Hip (clinicaltrials.gov) - Feb 9, 2016
P3, N=178, Completed, Sponsor: Charleston Laboratories, Inc
Recruiting --> Completed | N=810 --> 460 Active, not recruiting --> Completed | Trial primary completion date: Aug 2015 --> Jan 2015
- | Hydexor (promethazine/hydrocodone/acetaminophen) / Daiichi Sankyo, Charleston Labs
Trial completion, Trial primary completion date: A Double-Blind, Randomized, Active- and Placebo-Controlled, Multiple-Dose Multi-Center Phase 3 Study of the Safety and Efficacy of CL-108 in the Treatment of Moderate to Severe Acute Pain and Opioid-Induced Nausea and Vomiting (OINV) (clinicaltrials.gov) - Jan 29, 2016
P3, N=552, Completed, Sponsor: John Ameling
Active, not recruiting --> Completed | Trial primary completion date: Aug 2015 --> Jan 2015 Recruiting --> Completed | Trial primary completion date: Dec 2015 --> Jul 2015
- | Hydexor (promethazine/hydrocodone/acetaminophen) / Daiichi Sankyo, Charleston Labs
New P1 trial: A Four-Period, Four-Treatment, Four-Way Relative Bioavailability Study of CL-108 Under Fed and Fasted Conditions (clinicaltrials.gov) - Jun 9, 2015
P1, N=19, Completed, Sponsor: Charleston Laboratories, Inc
- |||||||||| Hydexor (promethazine/hydrocodone/acetaminophen) / Daiichi Sankyo, Charleston Labs
New P3 trial: A Multi-Center Actual-Use Study on the Safety of CL 108 for the Treatment of Moderate to Severe Acute Pain Associated With Osteoarthritis of the Knee or Hip (clinicaltrials.gov) - Jun 4, 2015
P3, N=150, Active, not recruiting, Sponsor: Charleston Laboratories, Inc
- || Hydexor (promethazine/hydrocodone/acetaminophen) / Daiichi Sankyo, Charleston Labs
New P3 trial: A Double-Blind, Randomized, Active- and Placebo-Controlled, Multiple-Dose Multi-Center Phase 3 Study of the Safety and Efficacy of CL-108 in the Treatment of Moderate to Severe Acute Pain and Opioid-Induced Nausea and Vomiting (OINV) (clinicaltrials.gov) - Jun 4, 2015
P3, N=550, Recruiting, Sponsor: John Ameling
- | sumatriptan succinate / Generic mfg.
Enrollment change: Efficacy and Safety of Oral Sumatriptan Plus Oral Promethazine in Migraine Treatment (clinicaltrials.gov) - Apr 18, 2013
P3, N=350, Completed, Sponsor: Shaheed Beheshti Medical University
Recruiting --> Completed | Trial primary completion date: Dec 2015 --> Jul 2015 N=250 --> 350
- | sumatriptan succinate / Generic mfg.
Trial completion: Efficacy and Safety of Oral Sumatriptan Plus Oral Promethazine in Migraine Treatment (clinicaltrials.gov) - Apr 18, 2013
P3, N=350, Completed, Sponsor: Shaheed Beheshti Medical University
N=250 --> 350 Recruiting --> Completed
- || sumatriptan succinate / Generic mfg.
New P3 trial: Efficacy and Safety of Oral Sumatriptan Plus Oral Promethazine in Migraine Treatment (clinicaltrials.gov) - Mar 17, 2013
P3, N=350, Completed, Sponsor: Shaheed Beheshti Medical University
- |||||||||| Hydexor (promethazine/hydrocodone/acetaminophen) / Daiichi Sankyo, Charleston Labs
New P3 trial: Phase III Study of the Safety and Efficacy of Cl-108 in the Treatment of Moderate to Severe Pain (clinicaltrials.gov) - Jan 29, 2013
P3, N=810, Recruiting, Sponsor: Charleston Laboratories, Inc